ライフサイエンスコーパス: DNA repair enzyme

1 dsDNA, implicating it as a flavin-dependent DNA repair enzyme.

2 Escherichia coli exonuclease III (ExoIII), a DNA repair enzyme.

3 ctions in alkylated base recognition by this DNA repair enzyme.

4 ts resembles the ATP-bound form of the Rad50 DNA repair enzyme.

5 ocated upstream of recG, encoding a putative DNA repair enzyme.

6 Thus, it may be a versatile DNA repair enzyme.

7 steps involved in damage recognition by this DNA repair enzyme.

8 ic endonuclease 1 (Ape1), the major oxidized DNA repair enzyme.

9 ified reaction mechanism for this intriguing DNA repair enzyme.

10 eveals that PE exemplifies a unique class of DNA repair enzyme.

11 may function as a general 3'-end-processing DNA repair enzyme.

12 inhibition of poly(ADP-ribose) polymerase, a DNA repair enzyme.

13 mising after possible down-regulation of the DNA repair enzymes.

14 ation and excision of damaged nucleobases by DNA repair enzymes.

15 about the impact of higher order folding on DNA repair enzymes.

16 y which Chk2 protein regulates expression of DNA repair enzymes.

17 hrough the relation between nitric oxide and DNA repair enzymes.

18 cDNA, and thereby prime it for processing by DNA repair enzymes.

19 ating intermediates may be a common theme in DNA repair enzymes.

20 A backbone distortion and may be targeted by DNA repair enzymes.

21 homologous to the helix-hairpin-helix (HhH) DNA repair enzymes.

22 belonging to the endonuclease III family of DNA repair enzymes.

23 he base excision repair (BER) superfamily of DNA repair enzymes.

24 . maritima UDG is a member of a new class of DNA repair enzymes.

25 s a member of the endonuclease III family of DNA repair enzymes.

26 ntially trigger reversion of the mutation by DNA repair enzymes.

27 ing helicases, polymerases, recombinases and DNA repair enzymes.

28 e cells to cope with DNA damage by utilizing DNA repair enzymes.

29 apurinic/apyrimidinic endonuclease family of DNA repair enzymes.

30 from photolyases, bacterial light-activated DNA repair enzymes.

31 A that may serve as a recognition signal for DNA repair enzymes.

32 nto a variety of proteins, including several DNA repair enzymes.

33 mage repair via interaction with a number of DNA repair enzymes.

34 and demonstrate this method using the human DNA repair enzyme 3-methyladenine DNA glycosylase (AAG).

35 nks inflammation in UC with increases in the DNA repair enzymes 3-methyladenine DNA glycosylase and a

36 n and identification of VPg unlinkase as the DNA repair enzyme, 5'-tyrosyl-DNA phosphodiesterase-2 (T

37 Unlike the homologous DNA repair enzyme 6-4 PHOTOLYASE, CRYs have extended car

38 sine (oxo8dG) levels and the activity of the DNA repair enzyme 8-oxoguanine DNA glycosylase (Ogg1) in

39 breast cancer by genetically modulating the DNA repair enzyme 8-oxoguanine DNA glycosylase (OGG1) in

40 lated to genes in bacteria and yeast for the DNA repair enzyme 8-oxoguanine DNA glycosylase.

41 Using histone demethylase JMJD1A and DNA repair enzyme ABH2 as examples, we show that this fa

42 ed aptamer selection to a medically relevant DNA repair enzyme, ABH2.

43 al mechanism to coordinate the activities of DNA repair enzymes across the genome.

44 action of a DNA recombinase and, once bound, DNA repair enzymes act to excise the nucleotide, replace

45 molysin protein nanopore was used to monitor DNA repair enzyme activity based on base-specific intera

46 The Escherichia coli DNA repair enzyme AlkB is a 2-oxoglutarate (2OG)-depende

47 umans express nine paralogs of the bacterial DNA repair enzyme AlkB, an iron/2-oxoglutarate-dependent

48 op a quantitative mechanistic scheme for the DNA repair enzyme AlkB.

49 erted into a substrate (ZP1BG) for the human DNA repair enzyme alkylguaninetransferase (AGT or SNAP-T

50 lonC), are released from DNA in vitro by the DNA repair enzyme alkylpurine-DNA-N-glycosylase (APNG).

51 The use of an inhibitor of a DNA repair enzyme alone to selectively kill a tumour, in

52 incorporation of HIF-1 and the bi-functional DNA repair enzyme and transcriptional coactivator, Ref-1

53 shed light on the interplay between central DNA repair enzymes and an essential molecular chaperone.

54 ion Factor for DNA (DNA-SPF), using specific DNA repair enzymes and antibodies, and Sun Protection Fa

55 ules, alone and in complexes with a suite of DNA repair enzymes and antibodies, to directly quantify

56 l terminus) domains are found in a number of DNA repair enzymes and cell cycle regulators and are bel

57 hat HhH motifs have been identified in other DNA repair enzymes and DNA polymerases, the HhH-DNA inte

58 ural insights into metal inhibition of other DNA repair enzymes and glycosylases.

59 ustard-DNA adduct is shielded by the ER from DNA repair enzymes and hence cells possessing an abundan

60 vergent interactions of HIV-1 and HIV-2 with DNA repair enzymes and SAMHD1 imply that these viruses u

61 ) for repairing molecular damage by means of DNA-repair enzymes and protein-repair enzymes such as me

62 he first such example of the regulation of a DNA repair enzyme, and identify a novel function of hnRN

63 activation-induced cytidine deaminase (AID), DNA repair enzymes, and post-class-switch expression of

64 zinc deficiency on DNA damage, expression of DNA-repair enzymes, and downstream signaling events in a

65 lation of the dual function reducing protein/DNA repair enzyme APE/redox factor-1(ref-1).

66 of the abasic site in the recognition by the DNA repair enzyme Ape1 is discussed.

67 Besides its prominent role as a DNA repair enzyme, APE1 was separately identified as a p

68 ges, there were progressive increases in the DNA repair enzyme APEX1, the cell cycle control proteins

69 ed expression of the essential base excision DNA repair enzyme apurinic endonuclease 1 (Ape1) in resp

70 glyceraldehyde-3-phosphate dehydrogenase and DNA repair enzyme apurinic/apyrimidinic endonuclease I p

71 w here that crocidolite asbestos induces the DNA repair enzyme, apurinic/apyrimidinic (AP)-endonuclea

72 Two other DNA repair enzymes are known to repair epsilon-base lesi

73 ts of this lesion and the various adducts on DNA repair enzymes are unknown, but their facile generat

74 (transposases, recombinases, integrases and DNA repair enzymes) are being harnessed or modified for

75 olymerase mu (pol mu) is a novel error-prone DNA repair enzyme bearing significant structural homolog

76 mu2 does not code for a DNA repair enzyme because mu2 mutants are not hypersensi

77 t are highly homologous to photoreactivating DNA repair enzymes but that function as blue light photo

78 n-sulfur cluster in DinG and likely in other DNA repair enzymes by NO may contribute to NO-mediated g

79 We investigated whether two human DNA repair enzymes can mediate OAS excision in vitro: Ap

80 c phenotype, such that animals lacking all 3 DNA repair enzymes cannot survive even a single bout of

81 tranded lesions affects their recognition by DNA repair enzymes, clustered damages are more difficult

82 It has been widely assumed that host DNA repair enzymes complete attachment of the remaining

83 Surprisingly, deficiency in all 3 DNA repair enzymes confers a massively synergistic pheno

84 An array of DNA-repair enzymes constitutes an essential part of the

85 An 8-OG:G mispair, if not corrected by DNA repair enzymes, could lead to G:C to C:G transversio

86 Cleavage assays with lesion-specific DNA repair enzymes coupled to ligation-mediated PCR show

87 e protein TP53I3, transcription factor ATF3, DNA repair enzyme DDB2, and the beta-adrenergic receptor

88 cent structures of the R283K mutant of human DNA repair enzyme DNA polymerase beta (pol beta) differi

89 We identified two promising genes in the DNA repair enzyme DNA polymerase beta and in the neuroen

90 valuated for inhibitory activity against the DNA repair enzyme DNA-dependent protein kinase (DNA-PK),

91 The DNA repair enzyme, DNA polymerase beta (Pol beta), is am

92 Only two DNA repair enzymes, DNA polymerase beta and O6-methylgua

93 ered Fe-S incorporation into MMS19-dependent DNA repair enzymes, DNA repair capacity, sensitivity to

94 mations of macromolecular substrates such as DNA repair enzyme/DNA transformations are commonly inter

95 onucleases (e.g., T7 gene 6 exonuclease) and DNA repair enzymes (e.g., uracil-DNA glycosylase).

96 purified a homologue of the Escherichia coli DNA repair enzyme endo nuclease III 5000-fold from calf

97 solated and probed with the Escherichia coli DNA repair enzyme endonuclease IV (endo IV), which recog

98 ology with the [4Fe-4S]2+ cluster-containing DNA repair enzyme, endonuclease III.

99 lished; these adducts are readily excised by DNA repair enzymes engaged in nucleotide excision repair

100 y of intramolecular electron transfer in the DNA-repair enzyme, Escherichia coli photolyase, a protei

101 l binding protein-interacting protein (CtIP) DNA repair enzyme, establishing a role for CtIP in regul

102 This DNA repair enzyme excises uracil residues in DNA that re

103 such as temozolomide lose their efficacy if DNA repair enzyme expression is upregulated.

104 unctionally significant differences exist in DNA repair enzyme extrahelical nucleotide binding and ca

105 Oligonucleotide purity is assayed using the DNA repair enzyme formamidopyrimidine DNA glycosylase an

106 uplex DNA substrates by the Escherichia coli DNA repair enzyme Fpg.

107 The Escherichia coli DNA repair enzymes Fpg and MutY are involved in the prev

108 on of DNA with histones in chromatin impedes DNA repair enzymes from accessing DNA lesions.

109 showed additional functional similarities to DNA repair enzymes from other organisms.

110 A DNA repair enzyme has recently been isolated from the io

111 steps, thought to be carried out by cellular DNA repair enzymes, have not been fully characterized.

112 Targeting the DNA repair enzyme human 8-oxoguanine DNA glycosylase (hO

113 xpression vector containing the gene for the DNA repair enzyme human 8-oxoguanine DNA glycosylase/apu

114 The DNA repair enzyme human uracil DNA glycosylase (UNG) sca

115 hemotherapeutics as inhibitors of a critical DNA repair enzyme, human AP endonuclease.

116 lymerase lambda (pol lambda), a low-fidelity DNA repair enzyme in the X-family that fills short nucle

117 The presence of multiple versions of DNA repair enzymes in a single organism is usually thoug

118 of chromatin, which presents a challenge to DNA repair enzymes in that recognition, incision, and re

119 ed a track that allows long-range sliding of DNA repair enzymes in their search for rare damage sites

120 Analysis of the involvement of DNA repair enzymes in trimethoprim-induced cytotoxicity

121 mal looping in CSR, and the roles of certain DNA-repair enzymes in CSR.

122 of tyrosyl-DNA-phosphodiesterase 1 (TDP1), a DNA repair enzyme, in ATL cells.

123 Maladaptive processing of the DNA damage by DNA repair enzymes, in particular by MutM and MutY DNA g

124 lesions are further processed by downstream DNA "repair" enzymes including error-prone translesion p

125 racteristic of the endonuclease IV family of DNA repair enzymes, including apurinic/apyrimidinic endo

126 Because many DNA methyltransferases and DNA repair enzymes induce similar DNA distortions, these

127 Therefore, targeting DNA repair enzymes into beta-cell mitochondria could be

128 an apurinic/apyrimidinic endonuclease 1 is a DNA repair enzyme involved in genome stability and expre

129 The promiscuity of DNA repair enzymes is particularly important, because it

130 a homologous family of endonuclease III-like DNA repair enzymes is present throughout phylogeny.

131 A hallmark of these and other DNA repair enzymes is their use of base flipping to sequ

132 Poly(ADP-ribose) polymerase-1 (PARP-1), a DNA repair enzyme, is involved in the induction of necro

133 ylpurine-DNA glycosylase (MPG), a ubiquitous DNA repair enzyme, is responsible for the removal of a w

134 proteolytic processing of PARP (the nuclear DNA repair enzyme known to be cleaved in association wit

135 lyase is unique in being the first and only DNA repair enzyme known to function via this novel enzym

136 nes induce iNOS and sufficient NO to inhibit DNA repair enzymes leading to the development and progre

137 phosphoesterase (PE) domain of the bacterial DNA repair enzyme LigD possesses distinctive manganese-d

138 We also found evidence that a DNA repair enzyme may play a role in modifying the seque

139 Thus, induction of DNA repair enzymes may be a unique strategy for neuropro

140 l extracts and COX activity, suggesting that DNA repair enzymes may be regulated by a mechanism diffe

141 NO inactivation of DNA repair enzymes may provide a link between inflammati

142 Mutant forms of the DNA repair-enzyme methylguanine methyltransferase in par

143 chemoprotection mediated by a mutant of the DNA-repair enzyme methylguanine methyltransferase could

144 Eukaryotic DNA repair enzymes must interact with the architectural

145 leases as well as lambda-exonuclease and the DNA repair enzymes MutH and Vsr, implying a common evolu

146 ne kinases with class II topoisomerases, the DNA repair enzyme MutL and the molecular chaperone Hsp90

147 and structurally elucidated a base-excision DNA repair enzyme, MutM, at the stage of initial encount

148 The DNA repair enzyme MutY plays an important role in the pr

149 The Escherichia coli DNA repair enzyme MutY plays an important role in the pr

150 The DNA repair enzyme MutY plays an important role in the pr

151 The Escherichia coli DNA repair enzyme MutY plays an important role in the re

152 The Escherichia coli DNA repair enzyme MutY plays an important role in the re

153 The Escherichia coli DNA repair enzyme MutY plays an important role in the re

154 Control of the N-glycosylase reaction by the DNA repair enzyme, MutY, entails the organization of sol

155 Editing of the pre-mRNA for the DNA repair enzyme NEIL1 causes a lysine to arginine chan

156 The DNA repair enzyme NEIL1 is a DNA glycosylase that is inv

157 The DNA repair enzyme O(6)-alkylguanine DNA alkyltransferase

158 ified using a lentiviral vector encoding the DNA repair enzyme O(6)-alkylguanine DNA alkyltransferase

159 emozolomide; however, gliomas expressing the DNA repair enzyme O(6)-methylguanine-DNA methyltransfera

160 lesion is removed in the normal cell by the DNA repair enzyme O(6)-methylguanine-DNA methyltransfera

161 Expression of the DNA repair enzyme O(6)-methylguanine-DNA methyltransfera

162 The DNA repair enzyme O6-methylguanine-DNA methyltransferase

163 stance gene, such as the P140K mutant of the DNA repair enzyme O6-methylguanine-DNA methyltransferase

164 The DNA-repair enzyme O6-methylguanine-DNA methyltransferase

165 let damage endonuclease (UVDE) is a 68.7 kDa DNA repair enzyme of Schizosaccharomyces pombe that reco

166 ic/apyrimidinic endonuclease (APE) family of DNA-repair enzymes of the DNase-I superfamily.

167 e product 8-oxoG and increased levels of the DNA repair enzyme OGG-1.

168 of uracil DNA glycosylase (UNG2), a cellular DNA repair enzyme, on the virus mutation rate and on rep

169 How DNA repair enzymes or complexes gain access to chromatin

170 osomes over DNA, the ionic dependence of the DNA repair enzyme PARP1 in DNA binding, and the interact

171 The DNA repair enzyme photolyase provides a natural system t

172 f sequence identity with the light-activated DNA repair enzyme photolyase.

173 ly conserved and structurally related to the DNA repair enzyme photolyase.

174 The same is also true for the DNA repair enzyme, photolyase.

175 ase caspase 3 and subsequent cleavage of the DNA repair enzyme poly (adenosine diphosphate [ADP]-ribo

176 nd subsequent cleavage of its substrate, the DNA repair enzyme poly (ADP-ribose) polymerase.

177 +/- 3.9%, p < or = .05), and activity of the DNA repair enzyme poly ADP-ribose synthetase (3.4 +/- 0.

178 reakage and the subsequent activation of the DNA repair enzyme poly(ADP ribose) synthetase (PARS).

179 thelial cells, which, in turn, activates the DNA repair enzyme poly(ADP)-ribose polymerase.

180 The DNA repair enzyme poly(ADP-ribose) polymerase (PARP) is

181 hanges were accompanied by activation of the DNA repair enzyme poly(ADP-ribose) polymerase (PARP), re

182 Inhibition of the DNA repair enzyme poly(ADP-ribose) polymerase 1 (PARP1)

183 appears to be mediated by activation of the DNA repair enzyme poly(ADP-ribose) polymerase and subseq

184 Activation of caspase-3 and the cleavage of DNA repair enzyme poly(ADP-ribose) polymerase were inhib

185 ting of DNA damage, excess activation of the DNA repair enzyme poly(ADP-ribose) polymerase, and deple

186 Inhibition of the DNA repair enzyme poly(ADP-ribose) polymerase-1 (PARP-1)

187 otinamide (1 mmol/L each), inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase.

188 cterized substrate of these proteases is the DNA repair enzyme poly(ADP-ribose) polymerase.

189 l models, possibly through inhibition of the DNA repair enzyme poly-ADP-ribose polymerase and prevent

190 and correlated with the inactivation of the DNA-repair enzyme poly(ADP-ribose) polymerase.

191 optotic enzyme caspase-3 and cleavage of the DNA-repairing enzyme poly-(ADP-ribose) polymerase.

192 Annexin V binding, the inactivation of the DNA repair enzyme, poly(ADP-ribose) polymerase, and the

193 the caspase inhibitors, an inhibitor of the DNA repair enzyme, poly(ADP-ribose) polymerase, conferre

194 This may be due to the activation of the DNA repair enzyme, poly(ADP-ribose) polymerase, in respo

195 -1(-/-) mice with targeted disruption of the DNA repair enzyme, poly(ADP-ribose) polymerase.

196 rting enzyme family-mediated cleavage of the DNA repair enzyme, poly(ADP-ribose) polymerase.

197 biquitinating activity regulate the cellular DNA repair enzyme polymerase eta and recruit it to poten

198 The DNA-repair enzyme, polymerase beta, was induced in the s

199 The dual function mammalian DNA repair enzyme, polynucleotide kinase (PNK), facilita

200 minase (AID) and is completed by error-prone DNA repair enzyme processing of AID-generated uracils.

201 ggest that Cry1 and Cry2, which evolved from DNA repair enzymes, protect genomic integrity via coordi

202 and two nonmembrane-bound ABC proteins, the DNA repair enzyme Rad50 and a structural maintenance of

203 X (a marker of double-strand breaks) and the DNA-repair enzyme RAD51.

204 lained by the impaired recruitment of a core DNA repair enzyme, RAD51, to replication-induced DNA dam

205 are strikingly reminiscent of one subset of DNA-repair enzymes, raising important mechanistic and dr

206 DNA repair enzymes recognize and remove damaged bases th

207 The process by which DNA repair enzymes recognize and selectively excise dama

208 The co-transcription factor and DNA repair enzyme, Redox effector factor-1/apurinic/apyr

209 radation enzymes, restriction endonucleases, DNA-repair enzymes, resolvases, intron splicing factors

210 transferase, thioredoxin, glutaredoxins, and DNA repair enzymes responded most strongly to cadmium an

211 roxynitrite, or that nitric oxide inhibits a DNA repair enzyme(s), leading to an increase in mutation

212 versed to two intact thymines in situ by the DNA repair enzyme SP lyase, an S-adenosylmethionine (S-A

213 versal of SP during spore germination by the DNA repair enzyme SP lyase.

214 haromyces pombe was initially described as a DNA repair enzyme specific for the repair of UV light-in

215 DNA repair enzymes such as human uracil-DNA glycosylase

216 rple acid phosphatases, 5'-nucleotidase, and DNA repair enzymes such as Mre11.

217 threonine phosphatases, 5'-nucleotidase, and DNA repair enzymes such as Mre11.

218 in several ubiquitin pathway proteins and in DNA repair enzymes such as Rad23, and they may be involv

219 the "base flipping" phenomenon found in many DNA repair enzymes such as T4 endonuclease V and uracil

220 fth member of the endonuclease III family of DNA repair enzymes, suggesting that the endonuclease III

221 itroimidazole may not be quickly repaired by DNA repair enzyme systems.

222 The bacterial DNA repair enzyme, T4 endonuclease V, delivered intracel

223 The DNA repair enzyme telomerase maintains chromosome stabil

224 less stable and more easily excised by human DNA repair enzymes than those containing the 10R (-) add

225 Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a DNA repair enzyme that acts upon protein-DNA covalent co

226 MutY is an Escherichia coli DNA repair enzyme that binds to 8-oxo-G:A and G:A mismat

227 Tyrosyl-DNA phosphodiesterase (Tdp1) is a DNA repair enzyme that catalyzes the hydrolysis of a pho

228 imidine/8-oxoguanine DNA N-glycosylase) is a DNA repair enzyme that catalyzes the removal of oxidized

229 e of apurinic endonuclease 1 (Ape1), a human DNA repair enzyme that cleaves adjacent to abasic sites

230 ue and a DNA 3' phosphate and functions as a DNA repair enzyme that cleaves stalled topoisomerase I-D

231 3-methyladenine DNA glycosylase I (TAG) is a DNA repair enzyme that excises 3-methyladenine in DNA an

232 Uracil DNA glycosylase (UNG) is a powerful DNA repair enzyme that has been shown to stabilize a gly

233 n abasic endonuclease, Ape1, is an essential DNA repair enzyme that initiates the removal of apurinic

234 es to process poly(ADP-ribose) polymerase, a DNA repair enzyme that is cleaved within minutes of the

235 uracil DNA glycosylase (UNG2) is a cellular DNA repair enzyme that is essential for a number of dive

236 r cross-complementation group 1 (ERCC1) is a DNA repair enzyme that is frequently defective in non-sm

237 hylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme that protects cells from carcinogenic

238 Uracil DNA glycosylase (UNG) is an important DNA repair enzyme that recognizes and excises uracil bas

239 rate recognition by Escherichia coli AlkB, a DNA repair enzyme that removes methyl adducts and some l

240 Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that removes peptide fragments linked

241 DNA alkyltransferase (AGT) is a single-cycle DNA repair enzyme that removes pro-mutagenic O(6)-alkylg

242 DNA polymerase (pol) beta is a two-domain DNA repair enzyme that undergoes structural transitions

243 Y is representative of a unique subfamily of DNA repair enzymes that also contain a [4Fe-4S]2+ cluste

244 te significantly to the specificity of other DNA repair enzymes that bind to extrahelical bases.

245 Contrary to many DNA repair enzymes that can directly reject non-target s

246 d 8-oxoGua-37-mer, a result similar to other DNA repair enzymes that catalyze N-glycosylase/AP lyase-

247 a conserved substrate recognition domain in DNA repair enzymes that couples ATP-hydrolysis to remode

248 The Rh-PPO mechanism is reminiscent of DNA repair enzymes that displace mismatched bases, and i

249 ay play an important role in the activity of DNA repair enzymes that initiate base excision by distor

250 role for the ubiquitous [4Fe-4S] clusters in DNA repair enzymes that involves redox chemistry and pro

251 deaminated purine nucleobases are essential DNA repair enzymes that protect the genome, and at the s

252 Genes coding for DNA repair enzymes that recognize 8-oxoguanine have been

253 that recognize nucleobases, including other DNA repair enzymes that recognize other types of extrahe

254 ses is a class of ubiquitous direct reversal DNA repair enzymes that remove alkyl adducts from nucleo

255 nstrate that the method, in conjunction with DNA repair enzymes that remove damaged bases to produce

256 ion by DNA polymerases work in parallel with DNA repair enzymes that remove lesions produced by modif

257 risons with other DNA methyltransferases and DNA repair enzymes that stabilize extrahelical nucleotid

258 GAA.TTC repeat during transcription attract DNA repair enzymes that then facilitate the expansion pr

259 Photolyases are DNA repair enzymes that use energy from blue light to re

260 ne methyltransferase (MGMT), which encodes a DNA-repair enzyme that confers resistance to the combina

261 rs have been observed previously in Nth/MutY DNA repair enzymes, this is the first observation of suc

262 s of proteins, e.g. molecular chaperones and DNA repair enzymes, thought to be ubiquitous and represe

263 acil and its derivatives in DNA are bound by DNA repair enzymes through hydrogen bonding and pi-pi st

264 FAN1 encodes a DNA repair enzyme, thus implicating abnormalities in DNA

265 Human (h) DNA repair enzyme thymine DNA glycosylase (hTDG) is a ke

266 er knockout or catalytic inactivation of the DNA repair enzyme thymine DNA glycosylase (TDG) leads to

267 ility of apoptosis by blocking the access of DNA repair enzymes to DNA strand breaks.

268 Therefore, targeting of DNA repair enzymes to mitochondria may be a viable appro

269 The topical application of DNA repair enzymes to sun-damaged skin of patients with

270 We tested the ability of three DNA-repair enzymes to remove lesions from the DNA strand

271 that interacts in a similar manner with the DNA repair enzyme UNG2 and repair factors XPA and RAD52,

272 We have investigated the inhibition of the DNA repair enzyme uracil DNA glycosylase (UDG) by an 11-

273 The DNA repair enzyme uracil DNA glycosylase (UDG) catalyzes

274 The DNA repair enzyme uracil DNA glycosylase (UDG) hydrolyze

275 The DNA repair enzyme uracil DNA glycosylase (UDG) is a powe

276 The DNA repair enzyme uracil DNA glycosylase (UDG) locates u

277 The DNA repair enzyme uracil DNA glycosylase (UDG) pinches t

278 The reaction catalyzed by the DNA repair enzyme uracil DNA glycosylase (UDG) proceeds

279 The DNA repair enzyme uracil DNA glycosylase (UDG) utilizes

280 A classic example is the DNA repair enzyme uracil DNA glycosylase (UDG) which rec

281 h complex along the catalytic pathway of the DNA repair enzyme uracil DNA glycosylase (UDG).

282 The DNA repair enzyme uracil DNA glycosylase catalyzes the f

283 The DNA repair enzyme uracil DNA glycosylase has been crysta

284 herein are for T4 polynucleotide kinase, the DNA repair enzymes uracil-DNA glycosylase (UDG) and form

285 Previous studies used the DNA repair enzyme UvrABC endonuclease in combination wit

286 21 years ago, the DNA Repair Enzyme was declared "Molecule of the Year".

287 nisms underlying cellular expression of this DNA repair enzyme, we focused on the role of a 59-bp enh

288 DNA-dependent PK (DNA-PK) is a DNA repair enzyme, which we previously found played an i

289 hways, mitochondrial proteins, histones, and DNA repair enzymes, which have not been associated with

290 g agents is limited because of the action of DNA repair enzymes, which mitigate the damage induced by

291 a Rrp1 (recombination repair protein 1) is a DNA repair enzyme whose nuclease activities include AP-e

292 Thus, Mug joins a very small coterie of DNA repair enzymes whose principal function is to avoid

293 tructurally homologous to exonuclease III, a DNA-repair enzyme with multiple activities.

294 in an increased nuclear localization of the DNA repair enzyme XPA.

295 he relationship between polymorphisms in the DNA repair enzyme, XRCC1 (codons 194, 280, and 399), and

296 Changes in gene expression for cytokines, DNA repair enzymes, zinc transporters, signaling molecul