ライフサイエンスコーパス: DNA transposon

1 econd is the transposase encoded by the Pogo DNA transposon .

2 e (retroelements) or via a DNA intermediate (DNA transposons).

3 strand breaks, or the expression of MIRAGE1 DNA transposons.

4 ivatives of the piggyBac and Sleeping Beauty DNA transposons.

5 hile 5'CAG...CTG3' occurs most frequently in DNA transposons.

6 ired inverted repeats more characteristic of DNA transposons.

7 repeats, a feature common to some classes of DNA transposons.

8 ralogs in a previously unidentified class of DNA transposons.

9 arry DNA fragments >10 kb is limited in most DNA transposons.

10 nsposable elements, with unusually prevalent DNA transposons.

11 Hsmar1 is a member of the mariner family of DNA transposons.

12 red to silence Tc3, but not other Tc/mariner DNA transposons.

13 es belong to two types: retrotransposons and DNA transposons.

14 Non-LTR retrotransposons represent 0.75%, DNA transposons 0.99%, whereas small RNA, simple repeats

15 We reported previously that the DNA transposon 1360 can enhance silencing of a reporter

16 t transposable elements (MITEs), remnants of DNA transposons, 4 simple sequence repeats, and low-copy

17 a) and spawned some of the largest bursts of DNA transposon activity ever recorded in any species lin

18 However, it is widely believed that DNA transposon activity has ceased in mammalian genomes

19 smissions of retroviruses and the absence of DNA transposon activity in the Old World monkey lineage.

20 Thus, these findings suggest that DNA transposon activity is a major evolutionary force in

21 integration that is afforded by this intact DNA transposon, activity that is mediated by the corresp

22 ressors are deficient in the repression of a DNA transposon and a retrotransposon-like element.

23 the integration capabilities of a eukaryotic DNA transposon and should prove useful in the treatment

24 between gene densities and the abundance of DNA transposons and a weak correlation between GR rates

25 ore often derived from retrotransposons than DNA transposons and as retrotransposon copy number in bo

26 Like bdelloid DNA transposons and Athena, these elements are found pre

27 Long Terminal Repeat retrotransposons, MuDR DNA transposons and intergenic sequences that contribute

28 2) The distribution of SCOP classes in DNA transposons and LINEs indicates that the proteins of

29 y, and highlight potential conflicts between DNA transposons and retrotransposons, major transposable

30 DNA transposons and retroviruses are versatile tools in

31 Activity of selected DNA transposons and the possibly related chromosomal bre

32 ibution of simple repeats, retrotransposons, DNA transposons, and nucleotide substitutions, but also

33 DNA transposons are defined segments of DNA that are abl

34 Strikingly, young X. tropicalis DNA transposons are derepressed and recruit p300 in hybr

35 xperiments to study the process by which Tn5 DNA transposons are identified and processed by their tr

36 DNA transposons are known in almost all well-studied org

37 ons and LINEs indicates that the proteins of DNA transposons are more ancient, containing folds that

38 right ends of many naturally active mariner DNA transposons are non-identical and have different aff

39 Our study suggests that some DNA transposons are still actively shaping some mammalia

40 g terminal repeat (LTR) retrotransposons and DNA transposons are transposable elements (TEs) that per

41 ts, one of the most diverse superfamilies of DNA transposons, are found in all eukaryotic kingdoms, b

42 contrast, LINE2 and other elements, such as DNA transposons, are more uniformly distributed in the g

43 e assessed the presence/absence of 794 human DNA transposons at orthologous positions in 10 mammalian

44 In general, the DNA transposons at the sun locus are older than the RNA

45 JMJ24 results in increased silencing of the DNA transposon AtMu1c, while overexpression of JMJ24 red

46 ctal cancer (CRC) in several Sleeping Beauty DNA transposon-based forward genetic screens in mice.

47 ceptibility gene in multiple Sleeping Beauty DNA transposon-based forward genetic screens in mice.

48 ds will increase applicability and safety of DNA transposon-based vector technologies.

49 DNA transposon-based vectors have emerged as gene vehicl

50 Bdelloids do contain numerous DNA transposons, both intact and decayed, and domesticat

51 s, except that the flanking element is not a DNA transposon but instead is long terminal repeat retro

52 tities and a high diversity of cut-and-paste DNA transposons, but no active representative of this cl

53 Mobilization of DNA transposons by transposase enzymes can cause genomic

54 report a previously uncharacterized class of DNA transposons called Polintons that populate genomes o

55 report here a superfamily of "cut and paste" DNA transposons called Transib.

56 ue of their inherent capacity to insert into DNA, transposons can be developed into powerful tools fo

57 3b and mir-427/430/302, as well as Harbinger DNA transposons carrying the Myb-like proto-oncogene hav

58 The DNA transposons constituted 13% of the D-genome compared

59 tivity in the mouse using a naturally active DNA transposon derived from the medaka fish called Tol2,

60 scribe a previously uncharacterized group of DNA transposons designated Phantom identified in the gen

61 Yet, it appears that the transfer of DNA transposons did not occur randomly as the same genom

62 cessation in the transpositional activity of DNA transposons during the later phase of the primate ra

63 This data points to intense activity of DNA transposons during the mammalian radiation and early

64 nterspersed repeats that resemble fossils of DNA transposons, elements that move by excision and rein

65 distinction to the preferences of the Hermes DNA transposon engineered to jump in yeast and the Tf1 r

66 tator-like transposable elements, a class of DNA transposons, exist pervasively in both prokaryotic a

67 Here, we identified a set of DNA transposon families dubbed SPACE INVADERS (or SPIN)

68 confidently estimate that at least 40 human DNA transposon families, representing approximately 98,0

69 Here, we report the discovery of ProtoRAG, a DNA transposon family from lancelets, the most basal ext

70 data to calculate the substitution rates of DNA transposons for each category and refine the age of

71 ger proteins are related to products of five DNA transposons found in fungi and nematodes, and more d

72 Mariner-like elements (MLEs) are DNA transposons found throughout the plant and animal ki

73 tional approach to identify the first active DNA transposons from rice and the first active miniature

74 In summary, HT of DNA transposons has contributed significantly to shaping

75 t how the distinctive biological features of DNA transposons have contributed to shape genome archite

76 DNA transposons have emerged as flexible and efficient m

77 a previously unknown category of eukaryotic DNA transposons, Helitron, which transpose by rolling-ci

78 igger1 and -2, that closely resemble pogo, a DNA transposon in Drosophila, and probably were responsi

79 ole of viruses in the horizontal transfer of DNA transposons in animals.

80 taxonomic distribution of all major types of DNA transposons in eukaryotes, including Helitrons and M

81 The diverse and recent populations of DNA transposons in genus Myotis will provide an unpreced

82 ilar terminal sequences with MITEs and other DNA transposons in human and other organisms.

83 Thus, DNA transposons in plants appear to be regulated by chro

84 l organization, and patterns of evolution of DNA transposons in rotifers of the class Bdelloidea, a g

85 s been tremendous recent activity of various DNA transposons in the bat lineage that far exceeds thos

86 is indicates that the horizontal transfer of DNA transposons in vertebrates might be more common than

87 ing members of the Tc1 family which includes DNA transposons in vertebrates, insects, nematodes and f

88 nd Helitron elements, two distinct groups of DNA transposons, in the lineage of the vespertilionid ba

89 Here we show how short, non-autonomous DNA transposons independently generated hundreds to thou

90 the genetic variation including a Harbinger DNA transposon insertion in the upstream regulatory regi

91 ggered-cut palindromic target site model for DNA transposon insertion.

92 DNA transposons integrate into host chromosomes with lim

93 sequence divergence, allowed us to classify DNA transposons into three different categories: anthrop

94 x, to catalyse the movement of a sequence of DNA (transposon) into a target DNA.

95 The Tc1/mariner family of DNA transposons is widespread across fungal, plant and a

96 Nearly all DNA transposons known previously in plants were present

97 ms might be intrinsically more vulnerable to DNA transposon lateral transfer, possibly because of a w

98 How do DNA transposons live in harmony with their hosts?

99 Class 2, or DNA transposons, make up approximately 3% of the human g

100 Unlike bdelloid DNA transposons, many of which are decayed, the newly de

101 proliferating elements illustrate a general DNA transposon mechanism that can plausibly account for

102 y we reported that in a few rice strains the DNA transposon mPing was increasing its copy number by a

103 we conducted an exhaustive search for human DNA transposons nested within L1 and Alu elements known

104 transposons, members of every superfamily of DNA transposons, numerous miniature elements, and novel

105 ave implicated the involvement of an ancient DNA transposon of the mariner family (Hsmar2) in the ini

106 parvovirus genome into a large virus-derived DNA transposon of the Polinton (polintovirus) family res

107 Cut-and-paste DNA transposons of the mariner/Tc1 family are useful too

108 DNA transposons offer an efficient nonviral method of pe

109 peat transposable elements are nonautonomous DNA transposons, often inserted in introns and untransla

110 thena, in large clusters composed of diverse DNA transposons, often inserted into each other, whereas

111 east two reactions during transposition of a DNA transposon or a retroviral cDNA.

112 DNA transposons, or class 2 transposable elements, have

113 prehensive analysis of the activity of human DNA transposons over the course of primate evolution usi

114 Here, we show that the DNA transposon piggyBac can mobilize 100-kb DNA fragment

115 The DNA transposon piggyBac is widely used as a tool in mamm

116 Since DNA transposons preferably insert near genes, this is co

117 ons are a recently discovered group of large DNA transposons present in diverse bacterial and archaea

118 3) DNA transposon proteins have lower contact order than ra

119 Transib is a superfamily of DNA transposons recently reconstructed in silico from de

120 of prokaryotes and eukaryotes indicates that DNA transposons recognize staggered-cut palindromic targ

121 All eukaryotic DNA transposons reported so far belong to a single categ

122 nt (TE) family in S. latifolia and the first DNA transposon residing on a plant Y chromosome.

123 Galileo is a DNA transposon responsible for the generation of several

124 tive DNA families were identified, including DNA transposons, retrotransposons and simple sequence re

125 Further investigation of non-LTR-RTs and DNA transposons revealed a negative correlation between

126 to the activities of mobile DNAs, including DNA transposons, RNA transposons, and endogenous retrovi

127 consisting of GC%, genes, retrotransposons, DNA transposons, simple repeats, and low complex repeats

128 ve elements (LINEs, endogenous retroviruses, DNA transposons, simple repeats, etc.) were significantl

129 ered into the genome via the Sleeping Beauty DNA transposon, suggesting that the observed methylation

130 However, the slow rate of proliferation of DNA transposons suggests that derivatives of the L1 retr

131 PIF-like elements belong to a new eukaryotic DNA transposon superfamily that is distantly related to

132 le, using the highly efficient piggyBac (PB) DNA transposon system.

133 Sleeping Beauty is an active DNA-transposon system from vertebrates for genetic trans

134 genesis system as an alternative to existing DNA transposon systems.

135 , we have focused on one particular group of DNA transposons that encode a transposase with a DD(E/D)

136 Both resemble bacterial composite DNA transposon Tn9, consisting of a core flanked by mobi

137 Pearl is the first putative nonautonomous DNA transposon to be identified in the phylum Mollusca.

138 Tdd-4 is the first DNA transposon to be isolated from Dictyostelium discoid

139 We show that DNA transposons transfer horizontally more often than re

140 little is known about how eukaryotic mariner DNA transposons trigger this step.

141 CDS by Sal-PIF, a 3100-bp PIF/Harbinger-like DNA transposon, whereas E(2) and E(3) originated from th

142 peat transposable elements (MITEs) are short DNA transposons with terminal inverted repeat (TIR) sign