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1 etect both siRNAs and a novel miRNA from the DNA virus.
2 highly structurally complex double stranded DNA virus.
3 f Bean dwarf mosaic virus, a single-stranded DNA virus.
4 ted with vaccinia virus (VACV), a vertebrate DNA virus.
5 derstanding the life cycle of this oncogenic DNA virus.
6 vaccinia virus (VV), a large (200 kB genome) DNA virus.
7 gainst a large range of viruses, including a DNA virus.
8 subsequent immune evasion by this prominent DNA virus.
9 sequences from a widespread single-stranded DNA virus.
10 oductive infection of this large cytoplasmic DNA virus.
11 of both is needed to control infection by a DNA virus.
12 igation of the oncogenic mechanisms for this DNA virus.
13 o largely take over study of double-stranded DNA viruses.
14 STING to initiate the antiviral response to DNA viruses.
15 s antiviral activity against several RNA and DNA viruses.
16 ba species are infected by the largest known DNA viruses.
17 replication intermediates produced by other DNA viruses.
18 stant to geminiviruses, a damaging family of DNA viruses.
19 f the suitability of bone for exploration of DNA viruses.
20 cellular immune response to infections with DNA viruses.
21 ical functions in defending the cell against DNA viruses.
22 gs to the Hepadnaviridae family of enveloped DNA viruses.
23 hologies associated with nuclear replicating DNA viruses.
24 aging motors in many complex double-stranded DNA viruses.
25 ositive-sense RNA viruses, retroviruses, and DNA viruses.
26 tly belonging to the nucleocytoplasmic large DNA viruses.
27 cytosolic DNA, cyclic di-GMP (c-di-GMP), and DNA viruses.
28 has not been described previously for human DNA viruses.
29 ed from polymerase II transcripts encoded by DNA viruses.
30 h antiviral activity against several RNA and DNA viruses.
31 ew is to explore recombination strategies in DNA viruses.
32 DNA structures generated upon replication of DNA viruses.
33 ulator of infection by VSV and other RNA and DNA viruses.
34 erferon responses to intracellular dsDNA and DNA viruses.
35 exhaustively studied of the double-stranded DNA viruses.
36 tivity against CMV and other double-stranded DNA viruses.
37 equences within the genomes of certain large DNA viruses.
38 of non-enveloped, circular, single-stranded DNA viruses.
39 sid expansion in the complex double-stranded DNA viruses.
40 ent results from other small single-stranded DNA viruses.
41 ycodnaviruses, and nuclear-cytoplasmic large DNA viruses.
42 f antiviral activity against a wide range of DNA viruses.
43 ories induced by the nucleocytoplasmic large DNA viruses.
44 proach as a treatment for diseases caused by DNA viruses.
45 or RNA viruses whereas PVG PCR detected more DNA viruses.
46 innate immune response to exogenous DNA and DNA viruses.
47 uction by a panel of pathogenic bacteria and DNA viruses.
48 obustly induced upon infection with multiple DNA viruses.
49 in that can be found in many double-stranded DNA viruses.
50 sponses against RNA viruses, but not against DNA viruses.
51 ral drugs for the treatment of infections by DNA viruses.
52 s of the protein kinase R pathway with large DNA viruses.
53 o cytosolic DNA, c-di-GMP, cGAMP, HIV-1, and DNA viruses.
54 the host innate immune response to HIV-1 and DNA viruses.
55 otinia sclerotiorum hypovirulence-associated DNA virus 1 and aNCV as within the insect-infecting Crip
56 leave us with a lesser understanding of how DNA viruses adapt to hosts and how the host responds to
57 dynamics and identify genes that are key to DNA virus adaptation, improving our understanding of how
61 ssential for innate immune responses against DNA viruses and bacteria such as Francisella and Listeri
63 ontaining proteins are encoded by many large DNA viruses and found in all domains of life, studies of
64 ity of RNA-Seq in detecting tumor-associated DNA viruses and identifying viral integration sites that
70 a gene conserved in nucleo-cytoplasmic large DNA viruses) and Organic Lake virophage OLV2 (conserved
72 sing mechanism of hepatitis B virus (HBV), a DNA virus, and the subsequent downstream signaling event
73 requirement in the antiviral response to two DNA viruses, and an unappreciated contribution to the in
74 e limited encoding capacity compared to many DNA viruses, and as a likely consequence, most open read
75 RV) and human Herpes simplex virus (HSV) are DNA viruses, and their pathogenesis and immunobiology ar
77 umber of sequences (P = 0.047) of persistent DNA viruses (anelloviruses, herpesviruses, papillomaviru
83 hich have the largest genome of nonenveloped DNA viruses, are being extensively explored for use in g
84 ge dsDNA viruses.IMPORTANCE Unlike all other DNA viruses, ascoviruses code for an executioner caspase
87 viruses 1 and 2 (HSV-1 and HSV-2) are large DNA viruses associated with recurring oral or genital er
89 e novo assembly of a novel, highly divergent DNA virus at the interface between the Parvoviridae and
91 nfection by a rapidly evolving single-strand DNA virus, beak and feather diseases virus (BFDV), which
92 less dependent on host functions than other DNA viruses because of their cytoplasmic site of replica
94 s (STING) is known be involved in control of DNA viruses but has an unexplored role in control of RNA
96 lyzing motor, formed in many double-stranded DNA viruses by a complex of a small terminase (S-termina
98 litis in susceptible mice.IMPORTANCE RNA and DNA viruses can cause encephalitis; in some cases, this
100 Human papillomaviruses (HPVs) are small DNA viruses causally associated with benign warts and mu
101 Hepatitis B virus (HBV), a small enveloped DNA virus, chronically infects more than 350 million peo
102 nt a global map of abundant, double-stranded DNA viruses complete with genomic and ecological context
104 ophages and certain nucleo-cytoplasmic large DNA viruses contain an unexpectedly diverse range of DNA
105 ral activity against a wide range of RNA and DNA viruses despite specifically targeting different pro
110 merous viral microRNAs (miRNAs) expressed by DNA viruses, especially herpesvirus family members, have
111 Accordingly, Nlrx1(-/-) mice infected with DNA viruses exhibit enhanced innate immunity and reduced
112 human cytomegalovirus (HCMV), a large human DNA virus, exploits IFITMs to facilitate the formation o
115 he ubiquitous human circular single-stranded DNA virus family Anelloviridae, there is still no convin
120 de editing through assembly methods in large DNA virus genomes raises dual-use concerns, we believe t
122 chanisms that a small RNA virus and a larger DNA virus have evolved to drive the fusion of viral and
125 In contrast to RNA viruses, double-stranded DNA viruses have low mutation rates yet must still adapt
130 ctional transcription factors of other large DNA viruses, IE1 is an essential, site-specific DNA-bind
131 ovides the first evidence of an encephalitic DNA virus in its natural host causing increased MMP acti
135 ase, is activated by single stranded RNA and DNA viruses in endocytic compartments resulting in endos
138 It is suitable for sequencing either RNA or DNA viruses in the field during outbreaks or as an inexp
139 ls were highly susceptible to infection with DNA viruses including HSV1, a variant of which is being
141 well-studied inhibitor of a range of RNA and DNA viruses, including influenza A virus (FLUAV) and hep
142 ic effector that restricts enveloped RNA and DNA viruses, including influenza A, Zika, Ebola, Sindbis
143 ice enhances infectivity by multiple RNA and DNA viruses, including orthomyxoviruses (influenza A), p
144 gly conserved in the complex double-stranded DNA viruses, including the herpesviruses and many bacter
145 zed as a broadly acting inhibitor of RNA and DNA viruses, including the orthomyxovirus influenza A vi
146 ism illustrates another novel means by which DNA viruses incorporate host death regulators that are m
147 dsDNA or infection of dendritic cells with a DNA virus induced the formation of dsDNA-Rad50-CARD9 sig
149 for recruitment to ALRs, as an inhibitor of DNA virus-induced activation of ALR inflammasomes in viv
152 The curiosity-driven discovery of giant DNA viruses infecting amoebas has triggered an intense d
153 alpha-helical TM proteins in double-stranded DNA viruses infecting bacteria and archaea reveals large
154 uses are a group of single-stranded circular DNA viruses infecting humans and other animal species.
156 r that is essential for host defense against DNA virus infection and appears important in defense aga
157 radigm of the role of Rb inactivation during DNA virus infection and uncovers the existence of an alt
158 he biology of these SINE ncRNAs, explore how DNA virus infection may lead to their induction, and des
172 nate immunity, leading to the persistence of DNA virus infections.Proteins of the TRIM family have re
173 oma-associated herpesvirus (KSHV), a nuclear DNA virus, inhibits mRNA export in a transcript-selectiv
176 viral particle stability for double-stranded DNA viruses is the energetically unfavorable state of th
177 roviruses (family Phycodnaviridae) are large DNA viruses known to infect certain eukaryotic green alg
178 -36 to regulate infection of closely related DNA viruses: KSHV, Epstein-Barr virus (EBV), and herpes
179 nderstanding of the evolution of other large DNA viruses, like poxviruses, that are reported to share
181 f baculoviruses, a group of insect-infecting DNA viruses, many of which have been used in biocontrol.
183 observation that the genomes of other large DNA viruses might bear SLAM family homologs further unde
184 omes make evolution in these double-stranded DNA viruses more efficient than that in smaller RNA viru
185 tibility to infection by the double-stranded DNA viruses mouse cytomegalovirus (MCMV) and human adeno
189 ey on giant viruses (nucleocytoplasmic large DNA viruses; NCLDVs), which are themselves parasites of
190 , is nearly identical by sequence to another DNA virus, NIH-CQV, previously detected in Chinese patie
195 h histones are found in the capsids of small DNA viruses (papovaviruses), none are found in the capsi
196 to have a role in the antiviral response to DNA viruses, physiological RNA species recognized by RIG
197 cribed to occur in 3 other families of large DNA viruses, poxviruses, baculoviruses, and mimiviruses,
198 egin to study natural variation, we analyzed DNA viruses present in the lower gastrointestinal tract
199 The recombinant baculoviruses produced viral DNA, virus progeny, and some viral proteins earlier duri
200 ion of a wide variety of analytes, including DNA, viruses, proteins, chemical vapors, and pesticides.
201 Poxviruses, a family of large cytoplasmic DNA viruses, rely on the intracellular membranes to deve
203 ruses, unlike many well-characterized animal DNA viruses, replicate entirely within the cytoplasm of
208 w that TRIM29 is induced upon infection with DNA viruses, resulting in degradation of STING, decrease
209 ahedral, membrane-containing double-stranded DNA virus--Salisaeta icosahedral phage 1 (SSIP-1) and it
210 ages are recently discovered double-stranded DNA virus satellites that prey on giant viruses (nucleoc
211 clic GMP-AMP synthase (cGAS) is an essential DNA virus sensor that triggers type I interferon (IFN) s
215 which IFNs, particularly IFN-gamma, inhibit DNA viruses such as cytomegalovirus (CMV) is still not f
220 h suppresses infection by a range of RNA and DNA viruses (such as influenza A virus [FluAV]), is inef
221 latively recent emergence of single-stranded DNA viruses, such as chicken anemia virus (CAV) and porc
223 cator of the possible presence of pathogenic DNA viruses, suggests that the thawing of permafrost eit
224 Most vertebrate and plant RNA and small DNA viruses suppress genomic CpG and UpA dinucleotide fr
225 mplex modifications of HSV-1 and other large DNA viruses than previous technologies, facilitating man
226 ia virus (CAV) is a single-stranded circular DNA virus that carries 3 genes, the most studied of whic
228 virus (HCMV) is an enveloped double-stranded DNA virus that causes severe disease in newborns and imm
229 galovirus (HCMV) is a large, double-stranded DNA virus that causes significant human disease, particu
230 bursaria chlorella virus 1 (PBCV-1), a large DNA virus that infects green algae, encodes a histone H3
232 African swine fever virus, a double-stranded DNA virus that infects pigs, is the only known member of
233 g multiple viral proteins encoded by a human DNA virus that inhibit the cGAS-STING DNA sensing pathwa
234 s sarcoma-associated herpesvirus (KSHV) is a DNA virus that is linked to several human malignancies.
237 is B and prototypic hepadnavirus, is a small DNA virus that replicates by protein-primed reverse tran
238 simplex virus 1 (HSV-1) is a double-stranded DNA virus that replicates in the nucleus of the host cel
239 newly discovered icosahedral double-stranded DNA virus that was isolated from an environmental sample
240 omaviruses are nonenveloped, double-stranded DNA viruses that are associated with both benign and mal
241 Polydnaviruses are large, double-stranded DNA viruses that are beneficial symbionts of parasitoid
242 e a unique group of circular double-stranded DNA viruses that are considered parasites of giant DNA v
244 on of a family of proteins encoded by insect DNA viruses that are homologous to a 12-kDa circulating
245 irus are small, nonenveloped single-stranded DNA viruses that are nonpathogenic in humans but have po
246 lomaviruses (PVs) are small, double-stranded DNA viruses that are responsible for cervical, oropharyn
247 sses, but also as a natural barrier for most DNA viruses that assemble their nucleocapsids in the nuc
248 ted viruses (AAVs) are small single-stranded DNA viruses that can package and deliver nongenomic DNA
249 ruses (HAdVs) are ubiquitous double-stranded DNA viruses that cause a wide array of diseases in human
250 nother potential target for gene editing are DNA viruses that cause chronic pathogenic diseases that
251 (HSV-1) and HSV-2 are large, double-stranded DNA viruses that cause lifelong persistent infections ch
253 constitute a large family of single-stranded DNA viruses that cause serious losses in important crops
255 Papillomaviruses are small, double-stranded DNA viruses that encode the E2 protein, which controls t
256 s 1 and 2 (HSV-1 and HSV-2) are large-genome DNA viruses that establish a persistent infection in sen
257 Adenoviruses are linear double-stranded DNA viruses that infect human and rodent cell lines, occ
260 pe 2 (GHV-2) genomes, generating recombinant DNA viruses that now circulate in wild birds and poultry
261 t and heterogeneous group of double-stranded DNA viruses that preferentially infect the cutaneous and
262 eport 18 genome sequences of double-stranded DNA viruses that putatively infect widespread sulfur-oxi
266 h the previously described icosahedral large DNA viruses, the Pandoraviruses appear unrelated to them
267 In most icosahedral double-stranded (ds) DNA viruses, the viral genome enters and exits the capsi
268 uppressed replication of a broad spectrum of DNA viruses through inhibition of mRNA transcription.
269 y mechanism we report allows double-stranded DNA viruses to achieve rapid, high-density packing of th
270 r evidence of the ability of double-stranded DNA viruses to acquire drug resistance through gene dupl
271 gene duplications can enable double-stranded DNA viruses to adapt rapidly to environmental pressures
273 ribe the structure of faustovirus, the first DNA virus (to our knowledge) that has been found to use
275 merges during infection with a retrovirus or DNA virus triggers antiviral type I interferon responses
279 arr virus and possible other double-stranded DNA viruses use TRIM29 to suppress local innate immunity
280 estimated the relative abundances of RNA and DNA viruses using a mass ratio approach and conducted sh
281 hat the genetic diversity of double-stranded DNA viruses was generated over long periods of time, sim
283 viruses and host genomes or between RNA and DNA viruses, was previously thought to be practically no
284 h human cytomegalovirus (HCMV), an enveloped DNA virus, we performed a semiquantitative, temporal ana
286 rgence of previously unknown double-stranded DNA viruses which delineate and extend the diversity of
288 rdance in exit strategies among some RNA and DNA viruses, which exploit autophagy pathway for their r
289 ruses that are considered parasites of giant DNA viruses, which in turn are known to infect eukaryoti
291 cytoplasmic innate recognition molecule for DNA viruses whose function is lost in a variety of cance
292 Human cytomegalovirus (HCMV) is a complex DNA virus with a 230-kb genome encoding 170 and up to 75
293 SFV) is a highly pathogenic, double-stranded DNA virus with a marked tropism for cells of the monocyt
295 epatitis B virus is a partly double-stranded DNA virus with several serological markers: HBsAg and an
296 available database of 3908 isolate reference DNA viruses with 264 413 computationally identified vira
297 n may provide a way for poxviruses and other DNA viruses with high-fidelity DNA polymerases to adjust
298 H(2)O(2) rapidly inactivates both RNA and DNA viruses with minimal damage to antigenic structure o
299 pic, nonenveloped, circular, double-stranded DNA viruses within the family Papillomaviridae that are
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