ライフサイエンスコーパス: DNA-binding activity

1 decreased, and there was a loss of NF-kappaB DNA binding activity.

2 nuclear localization of Sp1 and affects its DNA binding activity.

3 s in the hinge, also loses its site-specific DNA binding activity.

4 chromosome via an ATP-dependent nonspecific DNA binding activity.

5 phosphorylation, nuclear translocation, and DNA binding activity.

6 osphorylation of CREB in vitro inhibited its DNA binding activity.

7 avirus E1 and E2 proteins by modifying their DNA binding activity.

8 ragment compounds to find inhibitors of AgrA DNA binding activity.

9 reduced NF-kappaB nuclear translocation and DNA binding activity.

10 lfenic acid results in a ~4-fold increase in DNA binding activity.

11 nstructured aggregates with severely reduced DNA binding activity.

12 s nuclear localization and sequence-specific DNA binding activity.

13 tTR domain, a site known to be important for DNA binding activity.

14 tores p53 wild type conformation and rescues DNA binding activity.

15 at the polyomaviruses share this nonspecific DNA binding activity.

16 onse in osteoblasts by suppressing C/EBPbeta DNA binding activity.

17 DKN1A in a manner that is independent of its DNA binding activity.

18 lar endothelial growth factor, and NF-kappaB DNA binding activity.

19 a critical residue that negatively regulates DNA binding activity.

20 e-exposed cysteines without compromising its DNA binding activity.

21 ts and find that the ExsD.ExsA complex lacks DNA binding activity.

22 2Rbeta, JAK3, and STAT5, and abolished STAT5 DNA binding activity.

23 or NF erythroid-2-related factor 2 level and DNA binding activity.

24 regulation via a mechanism independent of IE DNA binding activity.

25 , which in Ets-1 allosterically inhibits the DNA binding activity.

26 ative function is known to inhibit C/EBPbeta DNA binding activity.

27 f the p50/p65 heterodimer inhibits NF-kappaB DNA binding activity.

28 also impairs both BAF's dimerization and its DNA binding activity.

29 rsed the inhibiting effect of H2S on the p65 DNA binding activity.

30 ing these contacts dramatically affects MepR-DNA binding activity.

31 T3-dependent gene expression by blocking its DNA-binding activity.

32 sential for homodimer formation and enhanced DNA-binding activity.

33 nts with transient neonatal diabetes abolish DNA-binding activity.

34 lei of irradiated cells and attenuated their DNA-binding activity.

35 also find that both BRG1 and hBRM BRDs have DNA-binding activity.

36 stream target genes reflects increased E2F-1 DNA-binding activity.

37 cal zinc finger motif with sequence-specific DNA-binding activity.

38 lation at lysine 310, thereby inhibiting its DNA-binding activity.

39 e a conformational change that gives rise to DNA-binding activity.

40 sed HIF-1alpha protein expression as well as DNA-binding activity.

41 domain destabilize the structure and reduce DNA-binding activity.

42 nding surface, consistent with their reduced DNA-binding activity.

43 depends on a subunit, Teb1, with autonomous DNA-binding activity.

44 highly conserved residues in NAD-responsive DNA-binding activity.

45 ed structure, but it does not have ATPase or DNA-binding activity.

46 MIP-2, and demonstrating enhanced NF-kappaB DNA-binding activity.

47 no effect on nuclear factor-kappaB and AP-2 DNA-binding activity.

48 ceptor and nuclear factor-kappaB (NF-kappaB) DNA-binding activity.

49 ols their translocation into the nucleus and DNA-binding activity.

50 scriptional repressor with sequence-specific DNA-binding activity.

51 53 via phosphorylation and activation of p53 DNA-binding activity.

52 haracterization of the SsOGT biochemical and DNA binding activities.

53 d DNA (ssDNA)-dependent ATPase, primase, and DNA binding activities.

54 naA, is highly conserved and has two crucial DNA binding activities.

55 ied TFs with methylated CpG (mCpG)-dependent DNA-binding activities.

56 2 oncogenicity relied on its demethylase and DNA-binding activities.

57 E1 results in the loss of sequence-specific DNA binding activity, a feature that is also conserved i

58 inactivated Cic by selectively disabling its DNA-binding activity, a mutation that causes derepressio

59 nding microarrays to assay sequence-specific DNA binding activity across 41 reference and 117 variant

60 erexpression reduces the amount of NF-kappaB DNA binding activity, activity of the upstream kinase IK

61 gnificant impact of the Pro76Leu mutation on DNA-binding activities, alterations in transactivating f

62 ed mutations in the B3 domain that disrupted DNA binding activity and characterized gene regulation b

63 ter inhibited CREB-mediated gene expression, DNA binding activity and chromatin occupancy proportiona

64 of the NF-kappaB p65 protein, as well as the DNA binding activity and DNA binding level of NF-kappaB

65 at the short Blimp-1Deltaexon7 isoform lacks DNA binding activity and fails to bind G9a or HDAC1/2 bu

66 helix transcription factor family that lacks DNA binding activity and has tumor suppressor function.

67 , and this was associated with enhanced CREB DNA binding activity and induction of IL-10.

68 showed that IR persistently induced NFkappaB DNA binding activity and NFkappaB-dependent TNFalpha tra

69 Importantly, nuclear localization, C/EBPbeta DNA binding activity and occupancy of the Rcan1-4 promot

70 ciated with increased in vitro p65 NF-kappaB DNA binding activity and p65 recruitment to the endogeno

71 uently, CS exposure resulted in enhanced Sp1-DNA binding activity and Sp1 trans-activation.

72 he C-terminal cleavage fragment retains both DNA binding activity and the ability to interact with AP

73 to evaluate TF variants for their impact on DNA binding activity and used universal protein-binding

74 has been well studied for over a decade, the DNA-binding activities and the biological functions of t

75 A corresponding decrease in Nrf2-DNA-binding activity and a general decrease in Nrf2-targ

76 e use of a Cas9 nuclease mutant that retains DNA-binding activity and can be engineered as a programm

77 B proteins, and resulted in decreased STAT-1 DNA-binding activity and formation of NF-kappaB p65/p50

78 e in cAMP responsive element binding protein DNA-binding activity and induction of Yes-associated pro

79 HIF1 recovered from exosomes retains DNA-binding activity and is transcriptionally active in

80 oprecipitation assays showed inhibited Stat3 DNA-binding activity and recruitment at CyclinD1 and c-M

81 MP-2 treatments, resulting in elevated Stat3 DNA-binding activity and recruitment on CyclinD1 and c-M

82 ral approach for the laboratory evolution of DNA-binding activity and specificity.

83 ) dioxygenase Ofd protein regulates both the DNA-binding activity and the degradation of the hypoxia

84 (C/EBP) beta was activated by LPS (increased DNA binding activity), and played a key role in LPS-indu

85 with LPS or TNF led to the phosphorylation, DNA binding activity, and chemokine promoter association

86 in Nrf2 protein, transcript expression, Nrf2-DNA binding activity, and expression of its transcriptio

87 Tetrameric BlcR(F147A) retained DNA binding activity, and importantly, this activity was

88 m in vitro resulted in a defect in Mlh1-Pms1 DNA binding activity, and in vivo proteolytic cleavage r

89 p65 phosphorylation, nuclear translocation, DNA binding activity, and recruitment to the MCP-1 promo

90 p65 phosphorylation, nuclear translocation, DNA binding activity, and recruitment to the MCP-1 promo

91 The L1 protein has DNA binding activity, and the L2 protein has multiple do

92 y blocks constitutive Stat3 phosphorylation, DNA binding activity, and transcriptional function in ma

93 had increased HIF-1alpha mRNA, protein, and DNA-binding activity, and alcohol feeding in HIF1dPA mic

94 Balpha), the translocation of p65, NF-kappaB DNA-binding activity, and its transcription activity.

95 uscle cells upon TLR4 stimulation, NF-kappaB DNA-binding activity, and subsequent inducible NO syntha

96 In Aiptasia, NF-kappaB protein levels, DNA-binding activity, and tissue expression increase whe

97 fective inhibitors of STAT3 phosphorylation, DNA-binding activity, and transactivation in vitro, lead

98 ge numbers of common target genes, but their DNA-binding activities are blocked by the gibberellin-in

99 .8-fold; both, p < 0.05) and increased GATA4 DNA binding activity as indicated by ELISA and by chroma

100 everse the IkappaB reduction and inhibit the DNA binding activity as well as nuclear translocation of

101 dependently of each other by virtue of their DNA binding activities, as a (sub)complex like other loa

102 Trim28 depletion increased E2F3 and E2F4 DNA binding activity, as measured by chromatin-immunopre

103 quinolinone inhibitor 1 (FQI1), inhibits LSF DNA-binding activity both in vitro, as determined by ele

104 p65 nuclear translocation and attenuates its DNA binding activity but has no effect on upstream prote

105 These proteins lack intrinsic DNA-binding activity but are recruited to specific genom

106 the heterotypic Brh2-Dss1 complex attenuates DNA binding activity, but not by direct competition for

107 apsilosis Est3 alone exhibits no appreciable DNA-binding activity, but can be crosslinked to telomeri

108 were found to have human IgG Fcgamma- and/or DNA-binding activity, but only TspB derivatives containi

109 ric form binds to NF-kappaB and enhances its DNA binding activity by directly reducing the cysteines

110 els were measured by immunoblot, STAT3-TGFB1 DNA-binding activity by chromatin immunoprecipitation, a

111 equired neither promoter vacancy nor loss of DNA-binding activity by Irr.

112 RORalpha inhibited E2F1 acetylation and its DNA-binding activity by recruiting histone deacetylase 1

113 Loss of Ikaros DNA-binding activity caused a local increase in chromati

114 of IkappaBalpha and inhibition of NF-kappaB DNA binding activity, caused by the nuclear IkappaBalpha

115 xamined the structural biochemistry of RPA's DNA-binding activity, combining small-angle X-ray and ne

116 estingly, mutations in FANCI that impair its DNA binding activity compromise DNA-stimulated FANCD2 mo

117 egulates Rgt1 function not by modulating its DNA-binding activity directly but by functionally antago

118 e resulting fusion proteins, while retaining DNA binding activity, display loss of subnuclear targeti

119 ding terminal inverted repeat (TIR) specific DNA-binding activity, DNA cleavage activity, albeit unco

120 which were attributed to impaired PPARalpha DNA binding activity due to reduced FABP1 protein levels

121 ithin the Runt domain of RUNX3 disrupts RUNX DNA binding activity during mitotic entry to facilitate

122 Although it does not have direct DNA-binding activity, EBNA3C plays a central role in the

123 that phosphorylation-dependent regulation of DNA binding activity evolved as a tunable mechanism to c

124 les, showed a 1.6-fold increase in NF-kappaB DNA binding activity following ECs.

125 2+)-dependent G protein, XLG2, promotes RTV1 DNA binding activity for a subset of floral integrator g

126 DNA-binding activity from a single domain is sufficient

127 ns are not the major single-strand telomeric DNA binding activities in A. thaliana and its close rela

128 ugh we detected four single-strand telomeric DNA binding activities in nuclear extracts from B. olera

129 ified human Mre11-W243R retains nuclease and DNA binding activities in vitro.

130 sary for redox regulation and enhancement of DNA binding activity in all three proteins.

131 NF-kappaB reporter, and increased NF-kappaB DNA binding activity in cultured neonatal rat ventricula

132 ranscription factor HSF1 mRNA expression and DNA binding activity in primary human monocytes and muri

133 er, how QslA binds to LasR and regulates its DNA binding activity in QS remains elusive.

134 mmunoprecipitation, and reduced TonEBP/NFAT5 DNA binding activity in the renal inner medulla.

135 erial RecO protein displays a zinc-dependent DNA binding activity in vitro and accelerates the anneal

136 horylation of YY1 at this site abolishes its DNA binding activity in vitro and in vivo.

137 Here we show that MDM2 inhibits p53 DNA binding activity in vitro and in vivo.

138 is Rex, we purified EF2638 and evaluated its DNA binding activity in vitro.

139 en oxidized and reduced cluster controls its DNA binding activity in vitro.

140 Altogether, we define novel DNA-binding activity in a conserved family of transcript

141 IF-1alpha messenger RNA (mRNA), protein, and DNA-binding activity in alcohol-fed mice compared with c

142 lpha and block p65 nuclear translocation and DNA-binding activity in lung tissues from OVA-challenged

143 transcriptional repressor that modulates its DNA-binding activity in response to NADH/NAD(+) ratio, h

144 Both inhibitors blocked STAT3 DNA-binding activity in vitro and in human glioma, breas

145 YqjI binding to nickel or iron reduces YqjI DNA-binding activity in vitro.

146 nscription factor, whose transcriptional and DNA-binding activities increased in MDDCs upon exposure

147 Cohesin's DNA binding activity is also promoted by the Eco1 acetyl

148 A non-sequence-specific DNA binding activity is also required for formation of t

149 in response to proteotoxic stress, and HSF1 DNA binding activity is elevated in cycling cells as com

150 tes, diphosphates and triphosphates, and its DNA binding activity is inhibited by triphosphates and d

151 The DNA binding activity is inhibited in vitro by Cu(II) or

152 hat in homologous proteins suggests that its DNA binding activity is regulated via a conformational c

153 This DNA binding activity is very poorly understood.

154 This bHLH DNA-binding activity is abolished if the C-terminal ACT

155 Bacteria possess transcription factors whose DNA-binding activity is altered upon binding to specific

156 Induction of AP1 in vitro DNA-binding activity is apparent within 1 h of PMA stimu

157 ng frequencies, indicating that the telomere DNA-binding activity is critical for TbTRF's role in VSG

158 e sensitive to redox conditions, since their DNA-binding activity is inhibited after incubation with

159 mechanism of cell cycle regulation, in which DNA-binding activity is intimately linked to the action

160 nits and demonstrate that high-affinity Teb1 DNA-binding activity is necessary and sufficient for cel

161 DNA-binding activity is required for both activation and

162 d knockin approaches show that enhanced JunD DNA-binding activity is required for increased expressio

163 1 acts as a transcription repressor, and its DNA-binding activity is strongly regulated in macrophage

164 Finally, we show that CIITA, which lacks DNA binding activity, is recruited to muscle-specific pr

165 In addition to DNA binding activity, it was critical that specific CpG

166 on the lagging strand daughter DNA, but its DNA binding activity mediated loading of Exo1 onto ssDNA

167 ocalized in the nucleus and showed increased DNA-binding activity, no change in the expression levels

168 anslated regions neither interfered with p53 DNA binding activity nor p53-mediated promoter transacti

169 ion in the N terminus of BRCA2 that exhibits DNA binding activity (NTD) and provide evidence for NTD

170 hibitor curcumin reverses the increased JunD DNA-binding activity observed in the absence of Nfe2.

171 acids are promising leads for suppression of DNA binding activities of B-ZIP and B-HLH-ZIP transcript

172 ular evidence that the cell cycle arrest and DNA binding activities of IE2 appear to be responsible f

173 The amounts and DNA binding activities of NFI proteins were similar in i

174 However, NaBu did not alter the DNA binding activities of Sp proteins or their expressio

175 r mechanism by which the 5mC hydroxylase and DNA binding activities of Tet3 cooperate to control targ

176 duced by inactivation of the translocase and DNA binding activities of the FANCM/MHF complex.

177 ubtilis, a model Gram-positive organism, the DNA binding activity of CtsR is regulated by McsAB-media

178 , disrupting TGFbeta signaling decreased the DNA binding activity of DNA methyltransferase DNMT1, sug

179 cleotide exchange predominantly regulate the DNA binding activity of DnaA and that those with low rat

180 Id2 inhibits the DNA binding activity of E proteins, whereas ankyrin-repe

181 MED25 also stimulates the in vitro DNA binding activity of ETV4 by relieving autoinhibition

182 The DNA binding activity of full-length Brh2 appears to corr

183 The DNA binding activity of full-length SaeR could be restor

184 Here, we characterize the DNA binding activity of Hox transcription factor complex

185 In aging cells, the DNA binding activity of HSF1 deteriorates correlating wi

186 housands of rare alleles likely to alter the DNA binding activity of human sequence-specific TFs.

187 A(98-239) is a suitable model to examine the DNA binding activity of human XPA.

188 phorylation, of p38 MAPK phosphorylation, of DNA binding activity of NF-kappaB and ATP content of Kup

189 Furthermore, IL-1alpha depletion reduced the DNA binding activity of NF-kappaB and C/EBPbeta, which s

190 uced apoptotic cell death and suppressed the DNA binding activity of NF-kappaB in a concentration dep

191 on by silencing SOD and catalase reduced the DNA binding activity of NF-kappaB in the transformed cel

192 The DNA binding activity of NF-kappaB is critical for VCAM-1

193 n of p-Akt, VEGF, Ang-1, Bcl-2, survivin and DNA binding activity of NF-kappaB were observed in the G

194 Trx is also known to activate the DNA binding activity of NF-kappaB, an important transcri

195 ity shift assay revealed that PMA stimulated DNA binding activity of NF-kappaB.

196 vation, NF-kappaB nuclear translocation, and DNA binding activity of NF-kappaB.

197 DNA binding activity of nuclear factor kappa B (NF-kappa

198 the combination gene therapy stimulated the DNA binding activity of nuclear factor-kappaB in the dia

199 The DNA binding activity of PrgX has additional indirect reg

200 n seed formation is tightly regulated by the DNA binding activity of protagonist basic leucine zipper

201 The DNA binding activity of RbkR was stimulated by CTP and s

202 ly expressed had the general single-stranded DNA binding activity of RPA complexes, unlike the telome

203 manner and that GTP-bound XLG2 promotes the DNA binding activity of RTV1.

204 ector factor 1, which is able to enhance the DNA binding activity of several transcription factors th

205 ort, we have developed assays to measure the DNA binding activity of Shelterin complexes in human cel

206 tion, low oxygen increases the stability and DNA binding activity of Sre1N.

207 We show that IgG IC-induced DNA binding activity of Stat3 in the lung was significan

208 It is generally accepted that global DNA binding activity of the NF-kappaB avian reticuloendo

209 We show that the DNA binding activity of the Soj dimer is required both f

210 s(203) disulfide bond appears to disrupt the DNA binding activity of the transcription factor.

211 vation, telomeres deploy the single-stranded DNA binding activity of TPP1/POT1a.

212 Taken together, inhibition of the DNA binding activity of transcriptional repressor OCT-1

213 the C-terminal WRKY domain and stimulate the DNA binding activity of WRKY33.

214 inc deprivation significantly suppressed the DNA-binding activities of HNF-4alpha and PPAR-alpha, and

215 Here, we reveal how distinct DNA-binding activities of Hop2-Mnd1 mediate the stabiliz

216 enylephrine stimulated the Ca(2+) -dependent DNA-binding activities of NFAT2, NFAT4, and Sp1 (but not

217 n of partition complexes requires ATPase and DNA-binding activities of ParA.

218 hibited form of B. subtilis GS regulates the DNA-binding activities of the TnrA and GlnR nitrogen tra

219 anism by which ligand binding attenuates the DNA-binding activities of these proteins.

220 The DNA-binding activity of AP-1 increased after stretch sti

221 CHOP10 by arsenic is associated with reduced DNA-binding activity of CCAAT/enhancer-binding protein b

222 e information about the domain structure and DNA-binding activity of D5, the poxvirus helicase-primas

223 creased the level of p53, independent of the DNA-binding activity of Dmp1.

224 ICL-induced RPA foci formation requires the DNA-binding activity of FAAP24 but not the DNA transloca

225 pression in CD4(+) T cells by regulating the DNA-binding activity of GATA-3 and limiting GATA-3 regul

226 Enhanced DNA-binding activity of heat shock transcription factor

227 by CBP has been implicated in inhibiting the DNA-binding activity of HSF.

228 To better understand the DNA-binding activity of human XPA in NER, we used NMR to

229 In functional assays, DNA-binding activity of I184M was reduced, resulting in

230 Correspondingly, P4 diminished the DNA-binding activity of NF-kappaB and the transcription

231 ls of p65 with corresponding increase in the DNA-binding activity of NF-kappaB as detected by electro

232 on of nuclear factor-kappaB (NF-kappaB), and DNA-binding activity of NF-kappaB compared with WT.

233 DNA-binding activity of NF-kappaB was higher in HSF-1(-/

234 AMF overexpression led to an increase in the DNA-binding activity of NF-kappaB, which, in turn, led t

235 f2 and its binding with Keap1, but decreased DNA-binding activity of Nrf2 and also its binding at the

236 45 prostate cancer cells, and suppressed the DNA-binding activity of nuclear factor-kappaB (NF-kappaB

237 tion domain in p53, which likely weakens the DNA-binding activity of p53 to the MIC-1 promoter.

238 the ParB/parS partition complex requires the DNA-binding activity of ParA, which transiently tethers

239 lignancy, using compounds that stimulate the DNA-binding activity of RAD51 to promote cancer cell dea

240 is regulate the phosphorylation level or the DNA-binding activity of response regulators such as Spo0

241 We conclude that DNA-binding activity of RPA2 is dispensable in yeast and

242 ging readouts allowed us to characterize the DNA-binding activity of SaCas9 and to optimize its sgRNA

243 TSA treatment did not alter the DNA-binding activity of Sp1 toward the P-Rex1 promoter;

244 However, DLX4 also bound and inhibited DNA-binding activity of Sp1.

245 y binds directly to the DBD and inhibits the DNA-binding activity of STAT3 both in vitro and in situ

246 hese tyrosine residues inhibits the promoter DNA-binding activity of T-bet.

247 These data demonstrate that the DNA-binding activity of Tal1 is not required to cooperat

248 dicating that the L1 loop contributes to the DNA-binding activity of TEAD.

249 Two block the DNA-binding activity of the CRISPR-Cas complex, yet do t

250 to physically interact with and modulate the DNA-binding activity of the major mitochondrial nucleoid

251 play complementary roles in determining the DNA-binding activity of the NF-kappaB proteins encoded b

252 We show that the DNA-binding activity of the S. globisporus orthologue of

253 al OB fold of STN1, but does not require the DNA-binding activity of this domain.

254 omain protein (PRH/Hhex) by CK2 inhibits the DNA-binding activity of this transcription factor.

255 A binding, had only a moderate effect on the DNA-binding activity of XPA.

256 lation of two of these sites can abolish the DNA-binding activity of YY1.

257 is there a metal preference for conferral of DNA-binding activity on the purified proteins.

258 subunits are required for sequence-specific DNA binding activity, only DmSNAP190 possesses a canonic

259 Disruption of E2F8's DNA binding activity phenocopied the effects of an E2f8

260 , or cAMP responsive element binding protein DNA-binding activity prevented the proliferative effects

261 een reported, the structural basis for XPA's DNA-binding activity remains unknown.

262 opy, the structural basis for regulating the DNA-binding activity remains unknown.

263 A well-characterized sequence-specific DNA binding activity resides in the E1 DBD and is used t

264 Our investigations of the DNA-binding activity reveal that although the formation

265 Unlike TBP, TRF2 lacks sequence-specific DNA binding activity, so the mechanism by which TRF2 is

266 Furthermore, through regions involved in DNA-binding activity, Sox2 and TLX physically interact t

267 compound appreciably affected STAT1 or STAT5 DNA-binding activities, STAT3-independent gene transcrip

268 teracted and restored the pM-inhibited Stat3 DNA-binding activity, suggesting IL-6/Stat3 signaling su

269 The E1 protein encodes two DNA binding activities that are required for initiation

270 FANCI and its C-terminal fragment possess a DNA binding activity that prefers branched structures.

271 hich might then reduce significantly the TR4 DNA binding activity that resulted in the suppression of

272 se in the phosphorylation of YY1 and loss of DNA-binding activity that can be reversed by dephosphory

273 inactivation causes changes in CREB and p65 DNA-binding activity that favors decreased proinflammato

274 als of pUL34 overlap the domain required for DNA-binding activity, the two regions are separable by p

275 otides tested, only cAMP was able to restore DNA binding activity to apo-Vfr.

276 induces target-proximal regeneration of ParA DNA binding activity to enforce processive and pole-dire

277 interaction with p53 DBD, SCH529074 restores DNA binding activity to mutant p53 and inhibits HDM2-med

278 getative viral DNA replication, restores the DNA binding activity to phosphorylated E1.

279 hat inhibit AP-2alpha protein expression and DNA binding activity to the PPARbeta/delta gene promoter

280 Here we show that Nfe2 represses JunD DNA-binding activity to the Gcm1 promoter during syncyti

281 1 enhances nuclear factor kappaB (NF-kappaB) DNA binding activity together with mutant p53 and induce

282 -driven phosphorylation of CcpA inhibits its DNA binding activity toward its regulon in S. aureus, re

283 anscription factors, we abrogated its global DNA-binding activity using a dominant-negative FOS pepti

284 lity shift assays demonstrated that the CcpA DNA binding activity was completely abrogated for the ph

285 High-glucose-stimulated FOXO1 DNA binding activity was mediated through TNF-alpha and

286 of the C216S mutant, a moderate increase in DNA binding activity was observed.

287 onsequently, accessibility of CNS-1 to GATA3 DNA binding activity was reduced in response to IFN-alph

288 omain function of VP1 mutants that lacked B3 DNA binding activity was sufficient for complementation

289 mbryonic fibroblasts (MEFs), and overall Egr DNA-binding activity was suppressed in Arf-deficient but

290 Although these agents display DNA binding activity, we observed that these compounds d

291 osphorylation of CREB at serine 133 and CREB DNA binding activity were abrogated in cells treated wit

292 lytic processing p105 and p100 and NF-kappaB DNA binding activity were elevated in these cells.

293 ression of Pin1 increases endogenous ERalpha DNA binding activity when activated by estrogen but not

294 s are required for synergy and show enhanced DNA-binding activity when both receptors are activated.

295 st individuals have unique repertoires of TF DNA binding activities, which may contribute to phenotyp

296 phorylation, its transcription activity, and DNA binding activity, which suggests that TGR5 antagoniz

297 la mutation leads to a ~60-fold reduction of DNA binding activity while a Cys to Ser substitution at

298 mitate-induced inflammation and p65-NFkappaB DNA binding activity, while C/EBPbeta overexpression ind

299 Estrogen enhances STAT-1 DNA-binding activity without increasing the expression o

300 ization, nuclear accumulation, and increased DNA-binding activity without p53 Ser15 phosphorylation.