ライフサイエンスコーパス: DNB

1 DNB caused abrupt depolarization of mitochondria in both

2 electrochemistry of 1,2-dinitrobenzene (1,2-DNB), 1,3-dinitrobenzene (1,3-DNB), and 1,4-dinitrobenze

3 esponse profiles for 1,3-dinitrobenzene (1,3-DNB) are independent of analyte concentration, analyte e

4 robenzene (1,2-DNB), 1,3-dinitrobenzene (1,3-DNB), and 1,4-dinitrobenzene (1,4-DNB) is strongly affec

5 With 1,2- and 1,3-DNB, the hydrogen bonding leads to irreversible chemistr

6 nzene (1,3-DNB), and 1,4-dinitrobenzene (1,4-DNB) is strongly affected by the presence of 1,3-dipheny

7 h irreversible behavior is observed with 1,4-DNB.

8 ves-like NACs such as 2,4-dinitrotoluene and DNB are detected at low part-per-billion levels in secon

9 tra, the concentrations of DNB, DNB(-*), and DNB(2-) were calculated, and from these concentrations,

10 At 30 days, group PRP presented NB and DNB significantly greater than group C.

11 Thus, dinitrobenzenide anion (DNB(-)) can be prepared in the two basic ion-paired form

12 ium salts of p-dinitrobenzene radical anion (DNB(-)).

13 Here we show that the Day/Night Band (DNB) low-light visible sensor on the recently launched S

14 unanticipated ability of the Day/Night Band (DNB) on the NOAA/NASA Suomi National Polar-orbiting Part

15 receptors a photolabile NMDA precursor (beta-DNB NMDA) was synthesized.

16 In rat hippocampal neurons the beta-DNB NMDA (250 microM) neither activated endogenously exp

17 DNB(2-), most likely by an ion pair between DNB(2-) and BMIm(+), which has been proposed by Minami a

18 ghput data, the dynamical network biomarker (DNB) can identify the pre-disease state, but this requir

19 new bone (NB), density of newly formed bone (DNB), new cementum (NC), and extension of remaining defe

20 lesions of the dorsal noradrenergic bundle (DNB) were assessed in animals trained in a task designed

21 rated" ion-pair salt isolated as K(L(C))(+)//DNB(-) is crystallographically differentiated from the "

22 " inner-sphere complex (IS(SIP)) of cofacial DNB(-)/DNB dyads.

23 Exposure to 1,3-dinitrobenzene (DNB) is associated with neuropathologic changes in speci

24 ction of sensitivity to 1, 3-dinitrobenzene (DNB)-induced mitochondrial permeability transition (MPT)

25 als of compounds such as 1,4-dinitrobenzene (DNB), which can be reduced in two one-electron steps.

26 r response to the toxicant m-dinitrobenzene (DNB).

27 The location of the dinitrobenzene (DNB) ring in the GSDNB-GSTM2-2 complex was modeled using

28 TNB), trinitrotoluene (TNT), dinitrobenzene (DNB), tetryl, and 2,4-dinitrotoluene (2,4-DNT) could be

29 lectron acceptors including dinitrobenzenes (DNBs) and naphthalenediimide (NI), which have been used

30 -sphere complex (IS(SIP)) of cofacial DNB(-)/DNB dyads.

31 ng these spectra, the concentrations of DNB, DNB(-*), and DNB(2-) were calculated, and from these con

32 contact" ion-pair salt isolated as K(L(E))(+)DNB(-) by their distinctive interionic separations.

33 ncreased in both SY5Y and C6 cells following DNB exposure by 4.6- and 6.0-fold above control, respect

34 The IC(50) values for DNB-related inhibition of MTT reduction were 107+/-25 mi

35 d with 1-glutathionyl-2,4-dinitrobenzene (GS-DNB) formed by a reaction in the crystal between GSH and

36 Three principal types of ion pairs, K(L)(+)DNB(-), are designated as Classes S, M, and C via the sp

37 tions between the expressions of DNB and non-DNB molecules, which can detect the pre-disease state re

38 d when the GST substrate o-dinitrobenzene (o-DNB) is added to the culture.

39 library was screened for loci that elevate o-DNB tolerance.

40 To recover genes that influence o-DNB resistance in S. cerevisiae, a high copy plasmid lib

41 n of Rod1p leads to resistance to not only o-DNB but also zinc and calcium.

42 T occurred at 10-fold lower concentration of DNB in SY5Y cells than in C6 cells.

43 Using these spectra, the concentrations of DNB, DNB(-*), and DNB(2-) were calculated, and from thes

44 pothesized to be sensitive to the effects of DNB lesions.

45 ial distributions between the expressions of DNB and non-DNB molecules, which can detect the pre-dise

46 underlie the cell-specific neurotoxicity of DNB.

47 ults were consistent with the protonation of DNB(2-), most likely by an ion pair between DNB(2-) and

48 ion, leading to an irreversible reduction of DNB in BMImNTf2.

49 and alpha-tocopherol, effectively prevented DNB-induced MPT in C6 and SY5Y cells, suggesting involve

50 The DNB ring makes a number of contacts with hydrophobic res

51 a novel computational approach based on the DNB theory and differential distributions between the ex

52 the second reduction potential of all three DNBs shifts substantially positive in the presence of th

53 pm (1 microg of analyte/1 g of soil) of TNB, DNB, TNT, tetryl, 2,4-DNT, 2,6-DNT, 2-NH2-4,6-DNT, and 4

54 10-fold more sensitive than glioma cells to DNB-induced decreases in mitochondrial reducing potentia

55 Exposure to DNB resulted in decreased cellular ATP content in SY5Y c

56 er than Bcl-2, correlates with resistance to DNB-induced MPT in SY5Y and C6 cells and that differenti

57 a and C6 glioma to respond to challenge with DNB.