ライフサイエンスコーパス: DSE

1 DSE are common among older adults, especially those with

2 DSE can be used to predict adverse outcomes after AMI.

3 DSE in autaptic cultures is both more robust and elicite

4 DSE is a feasible, safe and accurate screening method fo

5 DSE is less important for aggregates (reduced dipoles or

6 DSE may provide a way for cells to use their firing rate

7 DSE may represent one pathway through which spirituality

8 DSE was performed in 5-min stages with infusion of intra

9 DSE was performed with incremental doses with and withou

10 per 100 patients tested [95% CI, 0.11-0.29], DSE 24 [95% CI, 0.10-0.38], and coronary angiography 20

11 Analysis of Nank4-7* DSE structural energetics at room temperature as a funct

12 RRR: MPS, 1.09; 95% CI, 0.64-1.86; P = 0.74; DSE, 1.56; 95% CI, 0.71-3.45; P = 0.25).

13 RRR, MPS, 0.89; 95% CI, 0.38-2.10; P = 0.78; DSE, 1.09; 95% CI, 0.12-10.05; P = 0.93), and MACE (RRR:

14 Twenty-two patients had 91 DSE studies and 45 coronary angiograms.

15 aracterization of the Hrp1/Nab4 protein as a DSE-binding factor that activates NMD.

16 oup, Bigot et al. proposed the presence of a DSE motif in hAT transposases.

17 ex is active for searching and recognizing a DSE for approximately 200 nt 3' of the stop codon.

18 Hrp1p binds specifically to a DSE-containing RNA and interacts with Upf1p, a component

19 cted cardiac events after normal or abnormal DSE.

20 After DSE, subjects were monitored for TxCAD-related cardiac e

21 nts that occurred during the 12 months after DSE were tabulated: myocardial infarction (MI), cardiac

22 get HR is not uncommon despite an aggressive DSE regimen.

23 ficant changes in the body composition among DSE subjects, they experienced a decline in the Si and A

24 (RRR, 0.69; 95% CI, 0.49-0.96; P = 0.03) and DSE (RRR, 0.72; 95% CI, 0.50-1.02; P = 0.06), noninvasiv

25 ing guides secondary structure accretion and DSE contraction as solvent quality is decreased.

26 iate analysis of clinical, angiographic, and DSE variables revealed that the only independent predict

27 endocannabinoid release involved in DSI and DSE is likely to evoke endocannabinoid release in respon

28 DSI in the hippocampus, subthreshold MSE and DSE act synergistically.

29 corded from cultured hippocampal neurons and DSE evoked by a 15 s depolarization to 0 mV and MSE evok

30 Six months later, the PET and DSE studies were repeated, and the animals were euthaniz

31 00% of age-predicted maximum heart rate) and DSE (5 to 40 microg/kg/min at 3-min stages with or witho

32 during dobutamine infusion between RTCE and DSE.

33 acceptance scores were similar for TAPSE and DSE.

34 ApoAI DSE-4 is a multi-factor complex that includes an Sp/H4TF

35 complexes with the DSE (referred to as apoAI DSE-1, -2, -3, and -4).

36 Because apoAI DSE mutations revealed transcription defects in transien

37 The highest apoAI DSE-3 levels were observed with retinoic acid treated He

38 omoters and the hepatic-specific human apoAI DSE at Sp1 and H4TF2 binding sites.

39 an Sp/H4TF1 factor and either H4TF2 or apoAI DSE-3.

40 The apoAI DSE-1 and -2 complexes showed similar binding specificit

41 The apoAI DSE-1 complex was predominantly recognized by anti-Sp1 a

42 The apoAI DSE-2 complex was identified as H4TF1 and formed in the

43 The apoAI DSE-3 complex bound to a consensus GATA element within t

44 The apoAI DSE-3 complex was completely disrupted by a GATA-4 antib

45 the Sp/H4TF1 consensus site within the apoAI DSE.

46 annabinol, which has been shown to attenuate DSE, antagonizes MSE.

47 An additional requirement for autaptic DSE is filled internal calcium stores.

48 role in determining the duration of autaptic DSE.

49 of DAGLalpha substantially reduces autaptic DSE, shifting the "depolarization-response curve" from a

50 GRS) as an auxiliary downstream element (AUX DSE) which influences the processing efficiency of the S

51 This suggests that AUX DSE binding proteins may play an active role in stimulat

52 AUX DSEs, therefore, serve as a integral part of the polyade

53 First, AUX DSEs can promote processing efficiency by maintaining th

54 These novel AUX DSEs all influenced the efficiency of 3'-end processing

55 Second, AUX DSEs can enhance processing by forming a stable structur

56 Three possible mechanisms by which AUX DSEs mediate efficient in vitro 3'-end processing have b

57 Both DSE and synaptically evoked suppression of excitation (S

58 to inhibit EPSCs, yet readily occludes both DSE and EPSC inhibition by a synthetic CB1 agonist, WIN

59 cant change in rest or stress wall motion by DSE six months postoperatively in either group.

60 urgery over a three-year period, preceded by DSE, were included.

61 L123 had no significant effect on cerebellar DSE in MAGL(+/+) and (-/-) mice.

62 tes support and education control condition (DSE) among 4503 US adults with body mass index of 25 or

63 We report here that CB1-dependent DSE can be elicited from autaptic cultures of excitatory

64 We have recently reported that CB1-dependent DSE can be elicited in autaptic cultures of excitatory h

65 ) will result; we demonstrate fork-dependent DSEs proximal to Mu.

66 nto the study, 72 (92%) underwent diagnostic DSE by means of a standard protocol, 4.6 +/- 1.9 years a

67 Surprisingly, DAGLbeta knockdown diminishes DSE as much or more (ED(50) 6.4 seconds), suggesting tha

68 ith low to moderate risk of cardiac disease, DSE performed as part of an evaluation for liver transpl

69 without improvement in function at low dose DSE, who demonstrated worsening of function at a high do

70 e improvement of wall thickening at low-dose DSE may be limited in hibernating myocardium by severe h

71 (CB1R)--a possible mechanism underlying DSI/DSE.

72 4 women had wall motion abnormalities during DSE.

73 0.75 vs. 1.35 +/- 0.54, p < 0.05) and during DSE (2.11 +/- 0.67 vs. 1.21 +/- 0.41, p < 0.05) late aft

74 MCE and WMA for the detection of CAD during DSE have not been studied in a large number of patients.

75 Ventricular function during DSE was similar early and late after revascularization.

76 function also have improved function during DSE, particularly when there is evidence of ischemia bef

77 Patients with sustained improvement during DSE before revascularization had no significant change i

78 ities (WMAs) consistent with ischemia during DSE.

79 if >/=2 of 16 segments were ischemic during DSE.

80 no significant change in wall motion during DSE after angioplasty.

81 gnificant augmentation in wall motion during DSE after revascularization (WMSI 2.16 +/- 0.50 vs. 1.60

82 ost marked improvement in wall motion during DSE, those without recovery of rest function also have i

83 n of EDWT and any contractile reserve during DSE for recovery of regional function improved the speci

84 Patients with hypertensive response during DSE are more likely to have stress-induced myocardial is

85 he frequency of abnormal BP responses during DSE and their impact on accuracy of test results.

86 test or a dobutamine stress echocardiogram (DSE).

87 sfunction underwent rest 2D echocardiograms, DSE and rest-redistribution T1-201 tomography before rev

88 ities of dobutamine stress echocardiography (DSE) and rest-redistribution thallium-201 (T1-201) scint

89 s during dobutamine stress echocardiography (DSE) are associated with abnormal test results, nor if s

90 ied with dobutamine stress echocardiography (DSE) before TMLR.

91 value of dobutamine stress echocardiography (DSE) for assessment of cardiac risk before nonvascular s

92 uracy of dobutamine stress echocardiography (DSE) for evaluating posttransplant coronary artery disea

93 ility of dobutamine stress echocardiography (DSE) for evaluation of women with suspected ischemic hea

94 value of dobutamine stress echocardiography (DSE) for predicting long-term outcomes in a large cohort

95 and peak dobutamine stress echocardiography (DSE) for the diagnosis of coronary artery disease (CAD).

96 n during dobutamine stress echocardiography (DSE) has been increasingly used for detection of hiberna

97 R during dobutamine stress echocardiography (DSE) identifies viable myocardium that may improve in fu

98 f serial dobutamine stress echocardiography (DSE) in new heart transplant recipients and to examine t

99 perative dobutamine stress echocardiography (DSE) in patients who fail to achieve target heart rate (

100 ility of dobutamine stress echocardiography (DSE) in predicting cardiac events in the year after test

101 role of dobutamine stress echocardiography (DSE) in these patients, DSE was included in the preopera

102 y (MPS), dobutamine stress echocardiography (DSE) or coronary angiography, performed during preoperat

103 standard dobutamine stress echocardiography (DSE) protocol.

104 Because dobutamine stress echocardiography (DSE) provides assessment of left ventricular function an

105 PET) and dobutamine stress echocardiography (DSE) were performed to quantitate regional myocardial bl

106 entional dobutamine stress echocardiography (DSE) without contrast.

107 n during dobutamine stress echocardiography (DSE), particularly a biphasic response, predicts recover

108 ion (ILI) or diabetes support and education (DSE) on whom 2 y of data were collected.

109 B surgery or diabetes support and education (DSE).

110 ) site and an additional downstream element (DSE) located at the region of termination.

111 don and searches for the downstream element (DSE), whose recognition by the complex identifies the tr

112 nse codon for a downstream sequence element (DSE) associated with RNA-binding proteins.

113 romoter elements: a distal sequence element (DSE) at around -220, a proximal sequence element (PSE) a

114 at around -55 and a distal sequence element (DSE) at around -220.

115 ignal (PAS) and downstream sequence element (DSE) motifs drive broad alterations in 3' UTR isoform ex

116 transcription and a distal sequence element (DSE) required for activated transcription.

117 lar enhancers, the distal sequence elements (DSEs), and similar basal promoter elements, the proximal

118 er as the relevant endocannabinoid to elicit DSE.

119 RecA4142 was loaded at a double-strand end (DSE) of DNA.

120 s into a Mu target gap, a double strand end (DSE) will result; we demonstrate fork-dependent DSEs pro

121 es both a site-specific double-stranded end (DSE) and a Holliday junction.

122 a delay of its ending dates (dry-season end, DSE), and is accompanied by a prolonged fire season.

123 s not the sole source of double-strand ends (DSEs) during TLD, as previously proposed; models are sug

124 BDNF treatment blocked MSE and enhanced DSE.

125 Expression of H1a enhanced DSE and inhibited MSE at the same synapse.

126 rotein AI (apoAI) 48-bp downstream enhancer (DSE) were identified and characterized by electrophoreti

127 not present in the denatured state ensemble (DSE) or in intrinsically disordered proteins.

128 The denatured state ensemble (DSE) represents the starting state for protein folding a

129 om an equilibrated denatured state ensemble (DSE), we also do not get agreement with the equilibrium

130 nteractions in the denatured state ensemble (DSE).

131 e descriptions of denatured state ensembles (DSEs) remain unresolved.

132 sfection assays, we conclude that the entire DSE sequence is required for full apoAI transcriptional

133 mechanism when starting from an equilibrated DSE, when the simulation time is long enough to sample t

134 ng pilus subunit by a donor-strand exchange (DSE) mechanism.

135 membrane usher where donor strand exchange (DSE) replaces PapD's donated beta strand with an amino-t

136 arization-induced suppression of excitation (DSE) and inhibition (DSI) are forms of short-term neuron

137 arization-induced suppression of excitation (DSE) and inhibition (DSI).

138 arization-induced suppression of excitation (DSE) and metabotropic glutamate receptor (mGluR1)-mediat

139 arization-induced suppression of excitation (DSE) and metabotropic suppression of excitation (MSE).

140 arization-induced suppression of excitation (DSE) and reduced agonist-mediated desensitization of DSE

141 arization-induced suppression of excitation (DSE) is a form of cannabinoid CB(1) receptor-mediated in

142 arization-induced suppression of excitation (DSE) is a major form of cannabinoid-mediated short-term

143 arization-induced suppression of excitation (DSE) is accompanied by altered paired-pulse plasticity,

144 arization-induced suppression of excitation (DSE) is present in both SCs and basket cells.

145 arization-induced suppression of excitation (DSE), a CB1 receptor-dependent form of synaptic plastici

146 ppression of inhibition (DSI) or excitation (DSE).

147 pression of inhibitory (DSI) and excitatory (DSE) synapses by a mechanism that does not involve mGluR

148 ished a neuronal subpopulation that exhibits DSE and a differential complement of MSE-mediating Gq-co

149 e prevalence of daily spiritual experiences (DSE) and how they may relate to physical and mental heal

150 re- and postsynaptic machinery necessary for DSE but also that for MSE.

151 p = 0.0001) were shorter for TAPSE than for DSE.

152 gp46, but not EndoVII, regressed origin fork DSEs are processed by degradation of the DSE and a pathw

153 Frequent DSE were significantly associated with a higher number o

154 SE and white men reported the least frequent DSE (mean+/-SD 35.9+/-13.6 versus 52.2+/-19.1).

155 pain, and comorbid conditions, more frequent DSE were associated with increased energy (P<0.009) and

156 SE scores than men (reflecting more frequent DSE, mean+/-SD 37.3+/-15.0 versus 45.8+/-17.5; P=0.012).

157 an American women reported the most frequent DSE and white men reported the least frequent DSE (mean+

158 A graded DSE in 5-minute stages was performed in 214 patients (ag

159 However, DSE is usually negative in women with single-vessel sten

160 he study of cannabinoid signaling, including DSE.

161 Increased DSE may be associated with more energy and less depressi

162 Increasingly, DSE has been applied to risk stratification of patients.

163 ng-range contacts; however, the urea-induced DSE deviates from a random coil.

164 In contrast, the urea-induced DSE has significantly less residual secondary structure

165 d in buffer was compared to the urea-induced DSE.

166 ed suppression of excitation and inhibition (DSE and DSI) appear to be important forms of short-term

167 he incoming Nte is able to dock and initiate DSE due to inherent dynamic fluctuations within the chap

168 Women had significantly lower DSE scores than men (reflecting more frequent DSE, mean+

169 ent with the role of bona fide eCB mediating DSE.

170 dy of the roles of each isoform in mediating DSE.

171 s with arthritis reported significantly more DSE than those without arthritis (mean+/-SD 35.2+/-12.1

172 Negative DSE predicts short-term freedom from such events.

173 A negative DSE without resting WMAs has excellent NPV regardless of

174 urred in 2 of 50 children (4%) with negative DSE, versus 6 of 22 children (27%) with positive DSE (p

175 Of 397 negative DSEs, peak HR was <85% maximum predicted in 62 (16%).

176 t patients, all with normal or nondiagnostic DSE studies (negative predictive value 86%).

177 s DSE, and the agonist WIN 55,212-2 occludes DSE.

178 ignalling machinery: MSE mimics and occludes DSE and is itself occluded by the endocannabinoid 2-arac

179 respectively, compared with less than 2% of DSE participants (1.7% [95% CI, 1.2%-2.3%] for at least

180 wall thickening and improves the accuracy of DSE for detecting viable myocardium.

181 atergic neurons prolonged the time course of DSE in the amygdala, and impaired fear extinction in aud

182 reduced agonist-mediated desensitization of DSE.

183 The efficacy of DSE for detecting atherosclerotic coronary artery diseas

184 ansporter is necessary for the expression of DSE.

185 The transient nature of DSE--tens of seconds--is probably determined by the regu

186 r, the study provides an in-depth picture of DSE, including the first atomistic insights into the mol

187 core using clinical variables and results of DSE stratified patients into three risk groups for morta

188 ndertook this study to determine the role of DSE in risk stratification after AMI.

189 The sensitivity and specificity of DSE were 72% and 80%, respectively, when compared with c

190 al and astrocytic MAGL to the termination of DSE and DSI in Purkinje cells (PCs) in cerebellar slices

191 nificantly contributes to the termination of DSE at parallel fiber (PF) to PC synapses and DSI at put

192 isk scores nor long-term prognostic value of DSE has been described in a large diabetic population.

193 The positive predictive value of DSE was calculated for each BP group.

194 Positive predictive value of DSE was similar for patients who had hypertensive and no

195 hobic clusters might be a generic feature of DSEs that play a gatekeeping role to protect against agg

196 bese patients with diabetes who were offered DSE, a progressive decline in the glucose homeostasis an

197 of these patients had inducible ischemia on DSE (sensitivity 100%, specificity 63%).

198 us were assigned to RYGB surgery (n = 30) or DSE (n = 31).

199 ss echocardiography (DSE) in these patients, DSE was included in the preoperative evaluation.

200 ion scores were similar at baseline and peak DSE using both techniques.

201 at baseline (84%: Kappa = 0.59) and at peak DSE (88.9%: Kappa = 0.72).

202 agreements for detection of ischemia at peak DSE were superior for RT-3D, 92.7% compared with 84.6% f

203 n 30 s of each other at baseline and at peak DSE.

204 We performed DSE in 80 patients with CAD and LV dysfunction (ejection

205 Positive DSE identifies patients at increased risk of TxCAD-relat

206 ry angiography within 30 days after positive DSE.

207 t are not more likely to have false-positive DSE results.

208 =1905; 9%) were more likely to have positive DSE than those with normal (n=19 770; 90%) or hypotensiv

209 versus 6 of 22 children (27%) with positive DSE (p < 0.01).

210 In patients undergoing preoperative DSE, failure to achieve target HR is not uncommon despit

211 inoid CB1 receptor antagonist AM251 prevents DSE, and the agonist WIN 55,212-2 occludes DSE.

212 l)piperidine-1-carboxylate (JZL184)] prolong DSE in autaptic hippocampal neurons, whereas inhibition

213 show that genetic deletion of MAGL prolonged DSE at parallel fibre (PF) or climbing fibre (CF) to Pur

214 Hermes transposase differs from the proposed DSE motif.

215 l and anatomical evidence that MGL regulates DSE in autaptic hippocampal neurons and, taken together

216 Of 99 patients, 80% reported DSE most days and many times per day.

217 autaptic hippocampal neurons exhibit robust DSE.

218 t recipients were selected to undergo serial DSE at the time of their regularly scheduled endomyocard

219 nd processing but small changes in the short DSE severely reduced cleavage efficiency.

220 on each lithium and "dielectric solvation" (DSE, dielectric solvation energies), immersion of each m

221 t ischemia during dobutamine-induced stress (DSE) and compares the results with conventional two-dime

222 s Ischemia Syndrome Evaluation (WISE) study, DSE was assessed in women participating at the Universit

223 he prognostic value of a negative-submaximal DSE study before noncardiac surgery is unknown.

224 isease evaluated before nonvascular surgery, DSE had incremental value over clinical, electrocardiogr

225 These downstream regulatory elements, termed DSE, can bind c-Fos and JunD and transmit protein kinase

226 MAGL plays a predominant role in terminating DSE at climbing fiber (CF) to PC synapses, while both ne

227 More TAPSE than DSE studies were called "ischemic" (37% vs. 14%; p = 0.0

228 icipants lost significantly more weight than DSE participants at year 1 (net difference, -7.9%; 95% C

229 icipants lost significantly more weight than DSE participants at year 1 (net difference, -7.9%; 95% C

230 The DSE also bind related proteins of the CREB/ATF family.

231 The DSE populated in buffer was compared to the urea-induced

232 The DSE that is most relevant for folding is the ensemble po

233 The DSE, which contains an octamer motif, binds broadly expr

234 An interaction between the complex and the DSE-binding protein(s) triggers NMD.

235 sitioned nucleosome that resides between the DSE and the PSE.

236 suggests that a nucleosome lies between the DSE and the PSE.

237 RuvAB catalyzes RFR, RecJ and XonA blunt the DSE (created by the RFR), and then RecBCD loads RecA4142

238 Both the DSE and the PSE are protected from digestion, and the pa

239 NMD pathway, as a consequence of either the DSE being too far from a stop codon or the presence of t

240 taining mRNAs abolishes its affinity for the DSE and fails to interact with Upf1p.

241 -8.4%) at year 4, compared with 2.0% for the DSE group at both time points (95% CIs, 1.4%-2.6% at yea

242 ions, thus serving as useful proxies for the DSE of NTL9 in 8.3 M urea.

243 d low-likelihood long-range contacts for the DSE of NTL9.

244 traying hierarchical folding observed in the DSE at 55 degrees C are also often seen at room temperat

245 kg, respectively) but were unchanged in the DSE group (0.00 +/- 0.02 and 0.004 +/- 0.003 kg, respect

246 reveals residual secondary structure in the DSE in buffer, which is stabilized by both local and lon

247 ere are transient long-range contacts in the DSE in buffer.

248 Residual structure in the DSE influences the kinetics of protein folding, the prop

249 ficant, coupled interactions can form in the DSE of globular proteins, and can involve residues that

250 been used to infer residual structure in the DSE under nondenaturing conditions, but direct character

251 ing from higher energy subpopulations in the DSE.

252 nts from higher energy subpopulations in the DSE.

253 at residues are energetically coupled in the DSE.

254 ls, suggesting hydrophobic clustering in the DSE.

255 nsufficient to keep hydrophobes apart in the DSE.

256 ork DSEs are processed by degradation of the DSE and a pathway that includes recombination proteins.

257 icantly underestimate the variability of the DSE and DSL and their controlling processes.

258 h biases imply that the future change of the DSE and DSL may be underestimated by the climate project

259 Mutations that alter the energetics of the DSE can impact the analysis of cooperativity and folding

260 (June-August) seem to cause the delay of the DSE in austral spring (September-November).

261 study reveals the structural details of the DSE mechanism.

262 ion protection was also seen upstream of the DSE over a sequence corresponding to the binding site of

263 ortional to the inverse of the volume of the DSE, giving a compact species equivalent to a premolten

264 tion/termination cycle immediately 5' of the DSE.

265 The MC4R poly(A) site requires only the DSE and an A-rich upstream sequence to direct efficient

266 nd campaigns in years 2 to 4 (n=2241) or the DSE, which was an offer of 3 group sessions per year on

267 analysed the pattern of protection over the DSE and PSE of the U2 genes in mitotic cells.

268 transcribing polymerases accumulate over the DSE and that removal of this signal leads to transcripti

269 e pattern of methylation protection over the DSE is virtually identical to that obtained in vitro usi

270 mutant of NTL9, V3A/I4A-NTL9, populates the DSE in the absence of denaturant and is in slow exchange

271 mics simulations have been used to probe the DSE mechanism during formation of the Saf pilus from Sal

272 In this regard, the DSE behave as 12-0-tetradecanoylphorbol 13-acetate respo

273 cent pilus subunit was seen to stabilise the DSE product against unbinding, which also proceeded in t

274 Here we present data showing that the DSE of the N-terminal domain of the L9 (NTL9) ribosomal

275 era in gel shift assays, indicating that the DSE was recognized by multiple Sp family members.

276 eractions changes little on transferring the DSE from 6 M urea to water and then to 1 M TMAO, backbon

277 d 5.2 +/- 0.7 kg less after 2 y, whereas the DSE group did not change significantly (-0.4 +/- 0.6 and

278 s the multisubunit factor SNAPc, whereas the DSE recruits Oct-1.

279 sed to form four specific complexes with the DSE (referred to as apoAI DSE-1, -2, -3, and -4).

280 bound to a consensus GATA element within the DSE that was recognized by recombinant human GATA-6 as w

281 s seen in a primary care setting about their DSE, health perceptions, pain, energy, and depression.

282 r frequency of U and GU nucleotides in their DSE compared with canonical poly(A) signals.

283 two competing polyadenylation signals, this DSE increases the utilization of upstream poly(A) sites

284 Multivessel disease identified through DSE was more predictive of adverse outcome than was angi

285 Thus, DSE and DSI at different synapses is not uniformly affec

286 Of the 12 patients who underwent TMLR, DSE was repeated at 3 months postoperatively in 11 patie

287 ery of function and is a valuable adjunct to DSE in the assessment of myocardial viability.

288 been proposed as an efficient alternative to DSE.

289 In contrast to DSE, MSE undergoes heterologous desensitization over the

290 Patients who showed a biphasic response to DSE before revascularization (n = 12) had the most impro

291 icant improvement in wall motion response to DSE, particularly when ischemia was inducible before rev

292 atients who underwent liver transplantation, DSE was normal in 25, nondiagnostic in 34 because of ina

293 ional left ventricular dysfunction underwent DSE before, early (within 1 week) and late (>6 weeks) af

294 Enrolled subjects underwent DSE using a modified protocol.

295 AND We studied 21 949 patients who underwent DSE at Mayo Clinic, Rochester, MN, grouped by peak systo

296 patients (303 men, 227 women) who underwent DSE before nonvascular surgery and did not sustain an in

297 of 1,183 consecutive patients who underwent DSE were reviewed.

298 chest pain, or age > or = 60 years underwent DSE.

299 TMAO are reported on the thermally unfolded DSE of Nank4-7*, a truncated notch ankyrin protein.

300 performed in 70 patients were compared with DSE findings.