ライフサイエンスコーパス: Descemet

1 Descemet membrane detachment (DMD) is a significant comp

2 Descemet membrane detachment involved the visual axis in

3 Descemet membrane endothelial keratoplasty (DMEK) is a c

4 Descemet membrane endothelial keratoplasty may be furthe

5 Descemet membrane endothelial keratoplasty.

6 Descemet membrane endothelial keratoplasty.

7 Descemet membrane perforation was observed in 8 eyes (72

8 Descemet membrane rolling behavior showed significant in

9 Descemet membrane ruptures from blast exposure were desc

10 Descemet Stripping Automated Endothelial Keratoplasty (D

11 Descemet stripping automated endothelial keratoplasty (D

12 Descemet stripping automated endothelial keratoplasty af

13 Descemet stripping automated endothelial keratoplasty wi

14 Descemet stripping endothelial keratoplasty.

15 Descemet's membrane (DM) helps maintain phenotype and fu

16 Descemet's membrane detachment has been reported after n

17 Descemet's membrane is markedly thinned.

18 Descemet's membrane supports corneal endothelial cell re

19 Descemet's membrane was formed by a normal anterior band

20 Descemet's membrane was isolated from pig corneas and wa

21 Descemet's membrane with intact endothelium was dissecte

22 Descemet's stripping automated endothelial keratoplasty

23 Descemet's stripping automated endothelial keratoplasty

24 Descemet's stripping endothelial keratoplasty (DSEK) is

25 Descemet's stripping endothelial keratoplasty (DSEK) is

26 Descemet's stripping with automated endothelial keratopl

27 oidal effusion (1), vitreous hemorrhage (3), Descemet detachment (1), and persistent hyphema (2).

28 ould be completed using (a combination of) 4 Descemet graft unfolding techniques: (1) standardized no

29 In Group I, 93 Descemet stripping endothelial keratoplasty (DSEK) (51%)

30 nical feasibility and clinical outcomes of a Descemet membrane endothelial keratoplasty (DMEK) techni

31 of Fuchs endothelial dystrophy (primarily a Descemet membrane disorder), but not in bullous keratopa

32 terface, which may limit visual acuity after Descemet stripping automated endothelial keratoplasty.

33 Best-corrected visual acuity after Descemet's stripping endothelial keratoplasty (DSEK) ran

34 strategies that improve graft adhesion after Descemet membrane endothelial keratoplasty (DMEK) to red

35 nical outcome of 500 consecutive cases after Descemet membrane endothelial keratoplasty (DMEK), we ex

36 cal course of graft rejection episodes after Descemet membrane endothelial keratoplasty (DMEK).

37 igher-order aberrations (HOAs) in eyes after Descemet's membrane endothelial keratoplasty (DMEK), Des

38 fications of intraocular lenses (IOLs) after Descemet membrane endothelial keratoplasty (DMEK).

39 Endothelial migration after Descemet's stripping alone in the left eye, with probabl

40 Endothelial cell migration after Descemet's stripping procedure without insertion of endo

41 orneoscleral buttons (n = 10) obtained after Descemet's membrane endothelial keratoplasty.

42 may assist optimizing visual outcomes after Descemet stripping automated endothelial keratoplasty (D

43 lamellar keratoplasty (DALK) performed after Descemet stripping automated endothelial keratoplasty (D

44 much less frequent than those reported after Descemet's membrane endothelial keratoplasty.

45 lial cell (EC) loss and graft survival after Descemet's stripping automated endothelial keratoplasty

46 Although ECL 3 years after Descemet stripping automated endothelial keratoplasty is

47 All Descemet membrane endothelial keratoplasty surgical proc

48 Loosening of sutures occurred in 20%, and Descemet detachment in 16%.

49 1992-2013), ALK (date range, 2002-2013), and Descemet's stripping automated EK (date range, 2006-2013

50 ft infiltrate (3), graft dehiscence (3), and Descemet membrane detachment (2).

51 amber, and correlation between donor age and Descemet rolling behavior.

52 ing anterior lamellar keratoplasty (ALK) and Descemet's stripping endothelial keratoplasty (DSEK).

53 n) implantation within the capsular bag, and Descemet stripping automated endothelial keratoplasty us

54 amellar keratoplasty (ALK) in 165 cases, and Descemet stripping with endothelial keratoplasty in 64 c

55 Human corneal endothelial cells and Descemet's membrane (HCEC-DM) complex was dissected from

56 rneal epithelial basement membrane (EBM) and Descemet's membrane (DM) components exhibit heterogeneou

57 ody punctate staining in the endothelium and Descemet membrane; punctate staining was absent from bot

58 Analysis of the endothelium and Descemet's membrane (DM) was performed using transmissio

59 MEK consists merely of donor endothelium and Descemet's membrane, so DMEK does not create a stromal i

60 The epithelium and Descemet's membrane appeared normal.

61 ial keratoplasty (DSEK) in the right eye and Descemet's stripping only in the left eye.

62 pping automated endothelial keratoplasty and Descemet's membrane endothelial keratoplasty in their ma

63 riate number of fibroblastic cell layers and Descemet's membrane of appropriate thickness.

64 led a corneal ulcer with feathery margin and Descemet's membrane folding.

65 pithelium, epithelial basement membrane, and Descemet membrane.

66 scopy of the junction between the stroma and Descemet's membrane were performed.

67 Corneas were trephined, and Descemet's membrane with HCECs was stripped from the cen

68 nel have become comfortable and competent at Descemet's stripping automated endothelial keratoplasty

69 t 1 month, 12 of 13 patients had an attached Descemet membrane and improved mean logMAR BCVA (P = .00

70 A bare Descemet membrane was achieved in all cases.

71 The number of collagen lamellae between Descemet's membrane and most posterior keratocytes varie

72 e eye banks providing precut tissue for both Descemet stripping automated endothelial keratoplasty an

73 r treatment for endothelial dysfunction, but Descemet's membrane endothelial keratoplasty (DMEK) now

74 ndergoing cataract surgery alone followed by Descemet stripping endothelial keratoplasty (DSEK) or co

75 Human corneal endothelial cell-Descemet's membrane (HCEC-DM) complexes from normal and

76 While the literature on complex Descemet's membrane endothelial keratoplasty is limited,

77 ysis, the surgical videos of 100 consecutive Descemet membrane endothelial keratoplasty cases with at

78 Human corneal Descemet's membrane and corneal endothelial cells were d

79 showed the achieved big-bubble and detached Descemet membrane.

80 tionally, it revealed an associated detached Descemet membrane, a feature which has not been previous

81 's membrane endothelial keratoplasty (DMEK), Descemet's stripping automated endothelial keratoplasty

82 traoperative interface fluid dynamics during Descemet stripping automated endothelial keratoplasty (D

83 l surfaces in patients that underwent either Descemet-stripping-automated-endothelial-keratoplasty (D

84 To evaluate the utility of endothelial/Descemet membrane complex (En/DM) characteristics in dia

85 introduce and position the donor endothelium-Descemet membrane graft tissue.

86 basement membranes in wild-type eyes, except Descemet's membrane, showed immunogold labeling with ant

87 ss anterior stromal corneal scars (15 eyes), Descemet membrane ruptures (6 eyes), and conjunctival or

88 rring that may limit visual acuity following Descemet stripping endothelial keratoplasty (DSEK).

89 ear course of corneal densitometry following Descemet membrane endothelial keratoplasty (DMEK) for Fu

90 trating that endothelial cell loss following Descemet stripping automated endothelial keratoplasty (D

91 oplasty, along with the current evidence for Descemet's stripping automated endothelial keratoplasty

92 keratoplasty, may alter the indications for Descemet's stripping automated endothelial keratoplasty,

93 SAEK are comparable with those published for Descemet's membrane endothelial keratoplasty and better

94 bility of preloading endothelial tissues for Descemet membrane endothelial keratoplasty (DMEK).

95 best studied and the most widely used form; Descemet's stripping automated endothelial keratoplasty

96 tes were observed at variable distances from Descemet's membrane, increasing from 1.5 to 12 mum (mean

97 sterior polymorphous membrane dystrophy from Descemet's membrane specimens removed from each eye.

98 HCECs were then isolated from Descemet's membrane and cultivated.

99 e time required for the DMEK procedure (from Descemet scoring until final air filling) never exceeded

100 a was easily and reproducibly separated from Descemet's membrane with a combination of intrastromal c

101 ient), the anterior banded layer of the host Descemet membrane (DM) was still in situ across the corn

102 However, Descemet's membrane endothelial keratoplasty may be more

103 Stripped human Descemet membranes were digested with collagenase A, and

104 In Descemet membrane endothelial keratoplasty (DMEK), lamel

105 by marked corneal edema caused by a break in Descemet membrane, allowing aqueous to enter the corneal

106 year visual acuity and refraction outcome in Descemet stripping automated endothelial keratoplasty (D

107 ar keratoplasty, donor tissue preparation in Descemet's stripping endothelial keratoplasty, and shape

108 Intact Descemet's membranes isolated from bovine corneas were m

109 Although the intact Descemet membrane protects against dehiscing traumas aft

110 in 40 pseudophakic eyes after keratoplasty (Descemet stripping with endothelial keratoplasty [DSEK],

111 al epithelium, epithelial basement membrane, Descemet's membrane, ciliary epithelium, lens capsule, r

112 In the L450W mutant, Descemet's membrane was several times thicker than norma

113 es depending upon the presence or absence of Descemet's membrane.

114 antation, including increasing acceptance of Descemet's membrane endothelial keratoplasty, may alter

115 The increasing adoption of Descemet's membrane endothelial keratoplast is changing

116 -stromal scarring with a remaining aspect of Descemet's membrane rupture.

117 To report two cases of Descemet Membrane Endothelial Keratoplasty (DMEK) in pat

118 It is a major component of Descemet's membrane, a thick basement membrane under the

119 nectin and collagen type IV, constituents of Descemet's membrane.

120 ed at high levels along the anterior edge of Descemet's, another abnormal feature also found in late-

121 development of guttae, focal excrescences of Descemet's membrane.

122 e endothelial transplantation in the form of Descemet's stripping endothelial keratoplasty (DSEK) is

123 COL8A2 was observed in the anterior half of Descemet's membrane.

124 rior stroma and the anterior banded layer of Descemet's membrane.

125 This study evaluates the longevity of Descemet membrane endothelial keratoplasty (DMEK) grafts

126 osterior stroma (P<0.0001), opacification of Descemet's membrane (P<0.0001), and corneal guttae (P<0.

127 hed literature on the safety and outcomes of Descemet membrane endothelial keratoplasty (DMEK) for th

128 plicated by an intraoperative perforation of Descemet membrane; no other intraoperative or postoperat

129 of endothelial guttae, small protrusions of Descemet's membrane that are characteristic of FCD.

130 e of keratoplasty changed due to the rise of Descemet Membrane Endothelial Keratoplasty (DMEK).

131 served to crystallize the essential role of Descemet's stripping automated endothelial keratoplasty

132 This technique facilitates the separation of Descemet's membrane from the stroma without affecting en

133 entian violet S-stamp to the stromal side of Descemet membrane.

134 At 1 month, final status of Descemet membrane, final best-corrected visual acuity (B

135 Mean ECC loss after stripping of Descemet membrane was 3.9% (range, 6.5% gain to 14.5% lo

136 Demonstrating that success of Descemet stripping automated endothelial keratoplasty is

137 in DMEK can equal and even surpass those of Descemet stripping automated endothelial cell keratoplas

138 lial keratoplasty is limited, the utility of Descemet's stripping automated endothelial keratoplasty

139 age 5 demonstrates hydrops; 5a, acute onset: Descemet's membrane rupture and dilaceration of collagen

140 neal grafts post penetrating keratoplasty or Descemet stripping automated endothelial keratoplasty: 4

141 proposed that trophozoites cannot penetrate Descemet's membrane and the corneal endothelium to enter

142 The amoebae penetrated Descemet's membrane within 24 hours of in vitro culture.

143 hat A. castellanii is capable of penetrating Descemet's membrane and entering the AC.

144 dle into the deep stroma without penetrating Descemet's membrane.

145 e also greatly increased in the of posterior Descemet's membrane, yet another general feature shared

146 the existence of a distinctive acellular pre-Descemet's stromal layer in the human cornea.

147 such as acute hydrops, Descematocele and pre-Descemet's dystrophies.

148 -defined, acellular, strong layer in the pre-Descemet's cornea.

149 s corneal graft taken either from a previous Descemet stripping endothelial keratoplasty procedure or

150 icient technique for the preparation of pure Descemet membrane grafts.

151 (range, 2%-16%), and the complication rate (Descemet's folds, epitheliopathy, loose sutures) was 18%

152 PURPOSE OF REVIEW: Descemet's stripping endothelial keratoplasty (DSEK) has

153 uded stroma between the graft and the host's Descemet membrane, and approximately 6 mm in group B (23

154 overlapping between the graft and the host's Descemet membrane.

155 patient with acute edema due to spontaneous Descemet s (basement) membrane rupture in keratoconus, m

156 or toxic injury of the endothelium, stripped Descemet's membrane, epithelial toxicity and disruption,

157 or toxic injury of the endothelium, stripped Descemet's membrane, epithelial toxicity and disruption,

158 lagenase A, but not Dispase, of the stripped Descemet's membrane generated HCEC aggregates, which pre

159 t in a reproducible separation of the stroma-Descemet's junction.

160 peat descemetopexy for post-cataract surgery Descemet membrane detachment gives good anatomic and vis

161 d initial procedure in post-cataract surgery Descemet membrane detachment.

162 Recent literature demonstrates that Descemet's membrane endothelial keratoplasty provides be

163 The Descemet graft unfolding methods were categorized into 4

164 The Descemet membrane was thickened to a variable extent in

165 ng zone of interwoven collagen fibers at the Descemet-stroma interface, the findings did not provide

166 llagen types III and VI, was observed at the Descemet-stroma interface.

167 nique using a 27 gauge cannula to detach the Descemet membrane (DM).

168 CE cells scraped from the Descemet's membrane were counted.

169 pressure into the posterior stroma or in the Descemet membrane-stroma interface to create the bubble.

170 oid regime, and avoiding decentration of the Descemet graft.

171 ratoplasty (DMEK), lamellar splitting of the Descemet membrane (DM) may occur during stripping of hos

172 The OCT helped to assess the location of the Descemet membrane and guided the manual dissection.

173 nce of guttae, which are excrescences of the Descemet membrane.

174 patients had successful reattachment of the Descemet's membrane (DM) after the intervention.

175 1) creation of BB followed by peeling of the Descemet's membrane (DM); (2) peeling off of the DM foll

176 However, limitations of the Descemet's membrane endothelial keratoplasty procedure h

177 Stripping of the Descemet's membrane was performed under air and the graf

178 e IV collagen on the endothelial face of the Descemet's membrane; and abnormal deposition of stromal

179 A new technique to unfold the Descemet membrane grafts using a single cannula was desc

180 sing controlled techniques for unfolding the Descemet graft inside the recipient anterior chamber, ei

181 Therefore, Descemet's stripping without endothelial replacement was

182 al stroma as well as immediately adjacent to Descemet's membrane.

183 decreased immunologic rejection compared to Descemet's stripping automated endothelial keratoplasty.

184 idually variable distances of keratocytes to Descemet's membrane.

185 rane was absent, whereas its localization to Descemet's membrane was unchanged.

186 tes at the lower portions of guttae, next to Descemet's membrane, whereas CLU localized mostly on top

187 As surgeons transit to Descemet's membrane endothelial keratoplasty (DMEK), eye

188 aoperative macroperforation of the trabeculo-Descemet membrane (5.3%), hyphema (21.1%) and bleb forma

189 The 3-year success rate in eyes undergoing Descemet stripping automated endothelial keratoplasty wa

190 , but there is no staining in the underlying Descemet's membrane.

191 corneal patch graft, and 2 (1.9%) underwent Descemet stripping automated endothelial keratoplasty (D

192 edema from endothelial dysfunction underwent Descemet's stripping endothelial keratoplasty (DSEK) in

193 1090 individuals (1330 study eyes) underwent Descemet stripping automated endothelial keratoplasty (1

194 One hundred seventeen patients who underwent Descemet membrane endothelial keratoplasty (DMEK).

195 patients with Fuchs' dystrophy who underwent Descemet stripping automated endothelial keratoplasty (D

196 mmon anterior segment surgical procedure was Descemet stripping automated endothelial keratoplasty (D

197 e error after cataract surgery combined with Descemet stripping automated endothelial keratoplasty.

198 intraocular lens (IOL) who was treated with Descemet stripping endothelial keratoplasty (DSAEK).

199 However, unlike with Descemet's membrane endothelial keratoplasty, preparatio

200 nd abnormal assembly of collagen VIII within Descemet's membrane, a process that is presumed to begin

201 In recent years, Descemet membrane endothelial keratoplasty (DMEK) has ga