ライフサイエンスコーパス: Dictyostelium

1 tion leading to multicellular development in Dictyostelium.

2 n-based motility in cell-free systems and in Dictyostelium.

3 sis of the subunits' individual functions in Dictyostelium.

4 nant dynein fragments from budding yeast and Dictyostelium.

5 ing pathways, chemotaxis, and development in Dictyostelium.

6 d the contractile vacuole (CV) of the amoeba Dictyostelium.

7 Drosophila to polarization and chemotaxis in Dictyostelium.

8 GSK3 signaling throughout the development of Dictyostelium.

9 expression and cell type-specific sorting in Dictyostelium.

10 r the rapid sporulation of the social amoeba Dictyostelium.

11 tes the RasC-mediated activation of TORC2 in Dictyostelium.

12 d is involved in developmental cell death in Dictyostelium.

13 16) identified in cells of the social amoeba Dictyostelium a G protein-coupled receptor (GPCR) that r

14 In Dictyostelium (a social amoeba), Toxoplasma gondii (the

15 In Dictyostelium, a basal chemotaxis pathway consisting of

16 mpared the properties of purified endogenous Dictyostelium actin and mutant constructs with Tyr-53 re

17 hat directly interact with the SH3 domain of Dictyostelium actin-binding protein 1 (dAbp1).

18 ue, unbiased phenotypic chemotaxis-dependent Dictyostelium aggregation assay for high-throughput scre

19 e examine cell shape and movement in starved Dictyostelium amoebae during migration toward a chemoatt

20 Wildtype Dictyostelium amoebae feed on bacteria, but for decades

21 actor-1 (DIF-1) is a polyketide that induces Dictyostelium amoebae to differentiate as prestalk cells

22 Starvation induces Dictyostelium amoebae to secrete cAMP, toward which othe

23 face levels of the SibA adhesion molecule in Dictyostelium amoebae.

24 Diverse soil amoebas including Dictyostelium and Acanthamoeba can host intracellular ba

25 ated in survival during starvation in yeast, Dictyostelium and animals.

26 by pro-inflammatory mediators, chemotaxis of Dictyostelium and cell growth in Drosophila.

27 ionship is conserved in the simple eukaryote Dictyostelium and exploit this organism to define mechan

28 e (AMPK) has been proposed to play a role in Dictyostelium and human cytopathology in mitochondrial d

29 ies of both compounds were confirmed in both Dictyostelium and in human neutrophils in a directed EZ-

30 e observed for different chemoattractants in Dictyostelium and in human neutrophils, suggesting an ev

31 nd extend the reach of classical genetics in Dictyostelium and likely other systems as well.

32 The genetic/molecular model Dictyostelium and mammalian phagocytes share mechanistic

33 yosin II localizes to the cleavage furrow in Dictyostelium and metazoan cells remains largely unknown

34 ression during development of wild-type (WT) Dictyostelium and mutant cells lacking ChdC, a Type III

35 In the social amoeba Dictyostelium and probably many other unicellular eukary

36 ivating tyrosine kinase for GSK3 function in Dictyostelium and we now identify ZAK2 as the other tyro

37 e identified a Gbetagamma effector, ElmoE in Dictyostelium, and demonstrated that it is required for

38 as orthologue-specific degradation system in Dictyostelium, and further identification of the respons

39 show here that the inositol phospholipids of Dictyostelium are different, being highly enriched in an

40 We show that macropinocytic cups in Dictyostelium are organised around coincident intense pa

41 vity of at least one other chemorepellant in Dictyostelium, are not necessary for recombinant AprA ch

42 resistance in HR-deficient cells and present Dictyostelium as a convenient genetic model to character

43 ment the phenotypes, which further validates Dictyostelium as a model of the disease.

44 Using Dictyostelium as a model, we observe that a compression

45 Together, these data identify Dictyostelium as a novel model organism with the capacit

46 by prioritizing bacterial response genes in Dictyostelium as a novel model system for prokaryote-euk

47 Cell death in the model organism Dictyostelium, as studied in monolayers in vitro, can be

48 Dictyostelium biologists now face the widespread challen

49 for multicellular development of animals and Dictyostelium but are absent in plants and yeast.

50 TSET is non-essential in Dictyostelium, but may act in plasma membrane turnover,

51 utionize the field of functional genomics in Dictyostelium by greatly expanding the mutation spectrum

52 s of the alpha-actinin/spectrin subfamily of Dictyostelium calponin homology proteins.

53 tory subunit B56, encoded by psrA, modulates Dictyostelium cell differentiation through negatively af

54 P was not sufficient to induce cell death in Dictyostelium cell monolayers.

55 1evels of activated Rac in coronin-deficient Dictyostelium cells (corA(-)), which impacts myosin II a

56 Here we show that Dictyostelium cells accumulate extracellular polyphospha

57 When Dictyostelium cells are hyperosmotically stressed, STATc

58 Dictyostelium cells can move with both blebs and actin-d

59 Dictyostelium cells disrupted in exonuclease I, a critic

60 Dictyostelium cells exchange signals to position special

61 Dictyostelium cells exhibit kin discrimination--a potent

62 Dictyostelium cells have to judge when sufficient cell d

63 nd compared the traction stresses exerted by Dictyostelium cells lacking the SCAR/WAVE complex protei

64 Dictyostelium cells lacking the tumor suppressor PTEN sh

65 Consequently, Dictyostelium cells lacking WASH are unable to grow on m

66 ence that the actin machinery of chemotactic Dictyostelium cells operates close to an oscillatory ins

67 In addition, Dictyostelium cells polarize in response to extracellula

68 Previously, we found that chemotaxing Dictyostelium cells preferentially bleb from concave reg

69 Thus, heterologous expression system in Dictyostelium cells provides mechanistic and functional

70 regation of a whole developing population of Dictyostelium cells splits into two.

71 We show that Dictyostelium cells switch from using predominantly pseu

72 n multiple signaling pathways [6] can direct Dictyostelium cells to either cathode or anode.

73 Exposure of monolayer Dictyostelium cells to the signalling polyketide DIF-1 c

74 Dictyostelium cells were observed moving under agarose,

75 We analyzed the motility of Dictyostelium cells with bimodal analysis, a method that

76 AprA also causes chemorepulsion of Dictyostelium cells, and CnrN is required for this proce

77 ee-dimensional forces exerted by chemotaxing Dictyostelium cells, and examined wild-type cells as wel

78 stem in which human PTEN-GFP is expressed in Dictyostelium cells, we identified mutations in the memb

79 s proliferation and causes chemorepulsion of Dictyostelium cells, yet AprA has little sequence simila

80 and is essential for efficient chemotaxis of Dictyostelium cells.

81 ated human PTEN and expressed the library in Dictyostelium cells.

82 entally in both wild-type and myosin II null Dictyostelium cells.

83 transcriptional events in individual living Dictyostelium cells.

84 AprA acts as an autocrine chemorepellant for Dictyostelium cells.

85 In neutrophils and Dictyostelium, chemoattractant gradients generate direct

86 ic pathways for chemotaxis and phagocytosis; Dictyostelium chemotax toward bacteria and phagocytose t

87 We quantified Dictyostelium chemotaxis towards live gram positive and

88 for PKBA and PKBR1 and thus heavily affects Dictyostelium chemotaxis.

89 Strikingly, Dictyostelium chromatin may be organized in di-nucleosom

90 a2 binding partner that directly couples the Dictyostelium cyclic AMP GPCR to Rap1.

91 anisms, such as humans and the social amoeba Dictyostelium (Dd).

92 ation is important for oxygen-sensing during Dictyostelium development and is mediated by a HIF-alpha

93 PKA plays a critical role in Dictyostelium development but no CREB homologue has been

94 xylation of Skp1 contributes to O2-dependent Dictyostelium development, but full glycosylation at tha

95 that GskA is required during early stages of Dictyostelium development, in which it is necessary for

96 We have trapped the catalytic domain of Dictyostelium (Dicty) myosin II in a weak actin-binding

97 and AcgA, both essential for sporulation in Dictyostelium, did not affect Polysphondylium sporulatio

98 that transcript variability emerging during Dictyostelium differentiation is driven predominantly by

99 Here we show that the Dictyostelium diguanylate cyclase, DgcA, produces c-di-G

100 Here we use the Dictyostelium diploid system to replace the essential Ar

101 lysine-265 (K265) of the myosin-2 motor from Dictyostelium discoideum (Dd) is proposed to be a key re

102 Here we consider Dictyostelium discoideum (Dd), a member of the Amoebazoa

103 direction sensing based on experiments using Dictyostelium discoideum (Dicty).

104 In this study, PKAR and PDE from Dictyostelium discoideum (RD and RegA, respectively) wer

105 On food depletion, Dictyostelium discoideum amoebas collect into aggregates

106 Dictyostelium discoideum amoebas coordinate aggregation

107 DIRS-1 is the most abundant retroelement in Dictyostelium discoideum and constitutes the pericentrom

108 seudopod-dominated migration of the amoeboid Dictyostelium discoideum and for the lamellipod-driven m

109 ms that control multicellular development in Dictyostelium discoideum and reconstruct how some of the

110 Dictyostelium discoideum belongs to a group of multicell

111 Free-living cells of the social amoebae Dictyostelium discoideum can aggregate and develop into

112 Farmer clones of the social amoeba Dictyostelium discoideum carry bacteria to seed out new

113 Chemotaxing Dictyostelium discoideum cells adapt their morphology an

114 ne signal AprA, which is produced by growing Dictyostelium discoideum cells and inhibits their prolif

115 intracellular transport are investigated in Dictyostelium discoideum cells by single particle tracki

116 Upon starvation, individual Dictyostelium discoideum cells enter a developmental pro

117 antify the directional biases in chemotactic Dictyostelium discoideum cells in a flow chamber with al

118 e early stages of cytokinesis, in rounded-up Dictyostelium discoideum cells, the small G-protein Rap1

119 elay on the collective behavior of migrating Dictyostelium discoideum cells.

120 Two TCs from Dictyostelium discoideum converted farnesyl diphosphate

121 The social amoebae Dictyostelium discoideum cooperate by forming multicellu

122 d for cell surface cAMP receptors throughout Dictyostelium discoideum development, controlling chemot

123 Dictyostelium discoideum DgcA synthesized c-di-GMP in a

124 The simple eukaryote Dictyostelium discoideum displays chemotactic locomotion

125 roscopy we directly observe the structure of Dictyostelium discoideum dynein dimers on microtubules a

126 Dictyostelium discoideum encodes one Thg1 and three TLPs

127 In the Dictyostelium discoideum farming symbiosis, certain amoe

128 The amoeba Dictyostelium discoideum feeds on, and is colonized by,

129 melanogaster, Schizosaccharomyces pombe and Dictyostelium discoideum for methylation of the Geobacte

130 We show that the non-metazoan Dictyostelium discoideum forms a polarized epithelium th

131 The Dictyostelium discoideum genome encodes five proteins th

132 Here we show that the social amoeba Dictyostelium discoideum has a primitive farming symbios

133 Here we show that the model organism Dictyostelium discoideum has evolved to normally encode

134 The model organism Dictyostelium discoideum has greatly facilitated our und

135 Using bioinformatics tools, we show that Dictyostelium discoideum has the highest content of prio

136 The life cycle of the social amoeba Dictyostelium discoideum includes a multicellular stage

137 The social amoeba Dictyostelium discoideum integrates into a multicellular

138 ion-induced aggregation of the social amoeba Dictyostelium discoideum into a multicellular slug is kn

139 The social amoeba Dictyostelium discoideum is a professional phagocyte tha

140 The social amoeba Dictyostelium discoideum is a widely used model organism

141 Dictyostelium discoideum is an amoebozoa that exists in

142 es were explored for cellular ion imaging in Dictyostelium discoideum live cells but spontaneous dye

143 min G (ForG) from the professional phagocyte Dictyostelium discoideum localizes to endocytic cups.

144 n this paper, we show that WASH coats mature Dictyostelium discoideum lysosomes and is essential for

145 Dictyostelium discoideum MyoB is a class I myosin involv

146 ulticellular slug stage of the social amoeba Dictyostelium discoideum produce ETs upon stimulation wi

147 ew research indicates that the social amoeba Dictyostelium discoideum recognizes distinctions between

148 Here we show that Dictyostelium discoideum Roco4 is a suitable model to st

149 We show that, unexpectedly, Dictyostelium discoideum SCAR knockouts could still spre

150 Experiments on the social amoeba Dictyostelium discoideum show that the origins of lineag

151 The excitable cells of Dictyostelium discoideum show traveling waves of signali

152 ost is a "farmer" clone of the social amoeba Dictyostelium discoideum that carries and disperses bact

153 ady present in mycetozoan eukaryotes such as Dictyostelium discoideum This social amoeba kills bacter

154 emical mutagenesis in the social soil amoeba Dictyostelium discoideum Through genome sequencing, we s

155 show that PIP(3) is not only unnecessary for Dictyostelium discoideum to migrate toward folate, but a

156 In this paper, we exploit Dictyostelium discoideum to uncover a novel role for PAR

157 Dictyostelium discoideum transformed with mutant PfCRT e

158 The social amoeba Dictyostelium discoideum was selected for functional stu

159 mediated signaling network for chemotaxis in Dictyostelium discoideum We identified a negative regula

160 o used for communication in the social ameba Dictyostelium discoideum when the solitary cells aggrega

161 Our findings identified the slime mold Dictyostelium discoideum's CISD proteins as the closest

162 Using the amoeba Dictyostelium discoideum, a model system for the study o

163 Dictyostelium discoideum, a soil-dwelling social amoeba,

164 n phytate-loaded Acanthamoeba castellanii or Dictyostelium discoideum, and the intracellular growth d

165 In Dictyostelium discoideum, AprA and CfaD are secreted pro

166 In Dictyostelium discoideum, AprA is a secreted protein tha

167 ular slime molds, including the well-studied Dictyostelium discoideum, are amoebae whose life cycle i

168 from Schizosaccharomyces pombe and DnmA from Dictyostelium discoideum, are strongly stimulated by pri

169 n model organisms: Saccharomyces cerevisiae, Dictyostelium discoideum, Caenorhabditis elegans, Drosop

170 In many systems, including the social amoeba Dictyostelium discoideum, development is often marked by

171 some eukaryotes, including the social amoeba Dictyostelium discoideum, encode both a class I and a cl

172 In the social amoeba Dictyostelium discoideum, four signaling pathways act sy

173 T ortholog in the model developmental system Dictyostelium discoideum, in which Ca(2+) plays a role i

174 fied multiple PtdInsP(3)-binding proteins in Dictyostelium discoideum, including five pleckstrin homo

175 In Dictyostelium discoideum, loss of SCAR is compensated by

176 We show that in the nonmetazoan Dictyostelium discoideum, myosin II localizes apically i

177 ins from Homo sapiens, Arabidopsis thaliana, Dictyostelium discoideum, Saccharomyces cerevisiae, Esch

178 In an unrelated protist, Dictyostelium discoideum, Skp1 hydroxyproline is modifie

179 In the social amoeba Dictyostelium discoideum, starvation-triggered multicell

180 d in cheating behaviors in the social amoeba Dictyostelium discoideum, testing whether these genes ex

181 ate spore encapsulation in the social amoeba Dictyostelium discoideum, the metabolic profile and othe

182 Here we employ a simple eukaryote, Dictyostelium discoideum, to demonstrate distinct effect

183 Using a forward genetic screen in Dictyostelium discoideum, we identified the Ste20 kinase

184 Using the social amoeba Dictyostelium discoideum, we provide a possible explanat

185 tion can be manipulated in the social amoeba Dictyostelium discoideum, which allows us to test and co

186 ine repeats from the single-celled eukaryote Dictyostelium discoideum, which also has a multicellular

187 We test this evolutionary hypothesis in Dictyostelium discoideum, which forms multicellular frui

188 gets of the inhibitor (EC(50) >/= 50 muM) in Dictyostelium discoideum, while the strongest interactan

189 measured in chemotaxing unicellular amoeba, Dictyostelium discoideum.

190 h system is represented by the social amoeba Dictyostelium discoideum.

191 eukaryotic microbe (protist), the slime mold Dictyostelium discoideum.

192 on experiments on single cells of the amoeba Dictyostelium discoideum.

193 7C mutant of non-muscle myosin II motor from Dictyostelium discoideum.

194 three CHD orthologs (ChdA, ChdB and ChdC) in Dictyostelium discoideum.

195 odel organism database for the social amoeba Dictyostelium discoideum.

196 rward genetic approach in the model organism Dictyostelium discoideum.

197 diverse species including most metazoans and Dictyostelium discoideum.

198 he ampA gene has a role in cell migration in Dictyostelium discoideum.

199 y conserved between humans and the protozoan Dictyostelium discoideum.

200 red for normal chemotaxis and cytokinesis in Dictyostelium discoideum.

201 densis to predation by the phagocytic amoeba Dictyostelium discoideum.

202 through the social stage of an amoeba host, Dictyostelium discoideum.

203 ate via the complex life cycle of the amoeba Dictyostelium discoideum.

204 fflux or uptake systems in the social amoeba Dictyostelium discoideum.

205 were able to visualize polyP extracted from Dictyostelium discoideum.

206 sion of social cheating in the social amoeba Dictyostelium discoideum.

207 arity is mainly studied in the social amoeba Dictyostelium discoideum.

208 family of transcription factor subunits, the Dictyostelium enzyme (DdPhyA) contributes to O(2) regula

209 ress currently stores the data from over 800 Dictyostelium experiments and is embedded within a gener

210 ymes thus appear to mediate the synthesis of Dictyostelium extracellular polyphosphate, which is used

211 ostelids, including Dictyostelium purpureum, Dictyostelium fasciculatum and Polysphondylium pallidum.

212 e heterodimers complex in vivo with DGAP1, a Dictyostelium GAP protein.

213 We identify a Dictyostelium gene showing rapid transcriptional oscilla

214 ates the addition of the final two sugars in Dictyostelium, generating Galalpha1, 3Galalpha1,3Fucalph

215 We find that Dictyostelium genes are demarcated precisely at their 5'

216 ocytosis of bacteria induced upregulation of Dictyostelium genes encoding the copper uptake transport

217 rocal linking with dictyBase-a repository of Dictyostelium genomic data.

218 atorial regulation of GSK3 by ZAK kinases in Dictyostelium guides cell polarity, directional cell mig

219 in Dictyostelium, whereas human H-Ras and a Dictyostelium H-Ras homologue (RasC) are refractory to u

220 We also show that Dictyostelium has the capacity to suppress aggregation o

221 Dictyostelium histones are modified in response to DNA d

222 nability of c-di-GMP to induce cell death in Dictyostelium HMX44A cells and DH1 cells upon pharmacolo

223 ional myosin 7 (DdMyo7) in the social amoeba Dictyostelium However, the exact roles of these MyTH4-FE

224 Furthermore, similar to Dictyostelium htt(-) cells, siRNA-mediated knockdown of

225 e quiescence of organisms such as yeasts and Dictyostelium in response to nutritional starvation and

226 Studies in Dictyostelium indicate that TSET is a heterohexamer, wit

227 GbpC is a multidomain Roco protein in Dictyostelium, involved in transduction of intracellular

228 expulsion by the contractile vacuole (CV) in Dictyostelium is carried out by a giant kiss-and-run foc

229 Dictyostelium is the only non-metazoan with functionally

230 Dictyostelium is the only nonmetazoan with functionally

231 nism for interaction with the environment in Dictyostelium is unknown and thus, we explore different

232 mediated cytofission, originally observed in Dictyostelium, is relevant to human biology--where it se

233 Dictyostelium lacking P2XA receptors showed impaired reg

234 Dictyostelium lacks HIFalpha, and P4H1 modifies a differ

235 multiple unsuccessful attempts of generating Dictyostelium lkb1-null cells, an RNAi-based knockdown a

236 ACA produces the cAMP pulses that coordinate Dictyostelium morphogenetic cell movement and is highly

237 trate active nucleosome repositioning during Dictyostelium multicellular development, establish an in

238 By characterizing a Dictyostelium mutant defective in chemotactic responses,

239 This phenomenon was also observed in a Dictyostelium mutant lacking MidA (C2orf56/PRO1853/Ndufa

240 new perspective, we analyzed the motility of Dictyostelium mutants, and found four in which the coupl

241 The tail of Dictyostelium myosin IB (DMIB) also contains a BH site.

242 muscle myosin, beta-cardiac myosin (CMIIB), Dictyostelium myosin II (DdMII), and nonmuscle myosin II

243 We labeled a Cys-lite Dictyostelium myosin II motor domain with donor and acce

244 ns to resolve a structural transition in the Dictyostelium myosin II relay helix during the actin-act

245 spin label (BSL) bound stereospecifically to Dictyostelium myosin II, we determined with high resolut

246 The N-terminal MyTH/FERM region of Dictyostelium myosin VII (M7) has been isolated as a fir

247 two sequentially divergent IQ motifs of the Dictyostelium myosin-1C.

248 tic properties of the alpha-kinase domain of Dictyostelium myosin-II heavy chain kinase-A (termed A-C

249 Disruption of Dictyostelium Ndufaf5 leads to CI deficiency and defects

250 function is corroborated by localization of Dictyostelium NE81 at the nuclear envelope in human cell

251 ed that c-di-GMP could trigger cell death in Dictyostelium only in the presence of the DIF-1 polyketi

252 Here, we demonstrate RasG, the Dictyostelium orthologue of K-Ras, is targeted for degra

253 In Dictyostelium, oscillatory actin foci interact with sign

254 Dictyostelium p21-activated kinase B (PakB) phosphorylat

255 there is limited functional redundancy among Dictyostelium P2X receptors.

256 Loss of the Dictyostelium polyphosphate kinase DdPpk1 causes intrace

257 Pathological mutations were recreated in the Dictyostelium protein and expressed in the mutant backgr

258 gh basal and poststimulus phosphorylation of Dictyostelium protein kinase B (PKB) kinase family membe

259 We have previously shown that the Dictyostelium protein phosphatase 2A regulatory subunit

260 Dictyostelium provides an ideal system to examine the ex

261 For two of these taxa, the amoebozoan Dictyostelium purpureum and the jakobid Andalucia incarc

262 up to host multiple Dictyostelids, including Dictyostelium purpureum, Dictyostelium fasciculatum and

263 es of CP knockdown, overexpression of V-1 in Dictyostelium reduced the size of pseudopodia and the co

264 generation sequencing based inquiries by the Dictyostelium research community.

265 Here, we show that a Dictyostelium Rho GTPase, RacE, and a guanine nucleotide

266 ch inhibitors, we mutated the active site of Dictyostelium Roco4 kinase to resemble LRRK2.

267 Here we show that dephosphorylation of Dictyostelium SCAR controls normal pseudopod dynamics.

268 te that the C-terminal acidic domain of most Dictyostelium SCAR is basally phosphorylated at four ser

269 Under defined conditions, individual Dictyostelium secrete chemoattractants, migrate, and agg

270 By analogy to Dictyostelium Skp1, the mechanism may involve regulation

271 n can prolyl hydroxylate both Toxoplasma and Dictyostelium Skp1s.

272 The Dictyostelium stalk always forms at the organizing tip,

273 Studies in mammalian cells and Dictyostelium suggest that WASH functions primarily in a

274 lticellular development of the social amoeba Dictyostelium, suggesting it may serve as an important c

275 of SibA and the extracellular domain of the Dictyostelium surface protein csA also showed reduced st

276 In mammals and now in Dictyostelium, the hydrocarbon chains of inositol phosph

277 In Dictyostelium, the interaction of secreted cAMP with spe

278 In Dictyostelium, the mechanoenzyme myosin II and the actin

279 In the early chemotaxis studies in Dictyostelium, the rictor's ortholog has been identified

280 In Dictyostelium, this system tunes myosin II accumulation

281 y validated as necessary for the response of Dictyostelium to Gram-negative bacteria.

282 Here we exploit the model Dictyostelium to identify site-specific histone ADP-ribo

283 Here, we exploit the genetic versatility of Dictyostelium to investigate the effects of physiologica

284 In Dictyostelium, TORC2 functions at the front of migrating

285 e demonstrate that efficient polarization of Dictyostelium towards cAMP depends on ZAK1-mediated tyro

286 egulates multiple physiological processes as Dictyostelium transitions from a group of unicellular am

287 myosin 10 (Myo10) in mammalian cells and of Dictyostelium unconventional myosin 7 (DdMyo7) in the so

288 Here we show that Dictyostelium utilizes a CREB-like protein, BzpF, to int

289 Accumulated Cu(I) in Dictyostelium was monitored using a copper biosensor bac

290 We report that, in Dictyostelium, WASH is also required for the lysosomal d

291 Using Dictyostelium, we demonstrate that WASH drives protein s

292 -type PHDs is expressed in the social amoeba Dictyostelium where it also exhibits characteristics of

293 r modification is found in the social amoeba Dictyostelium, where it regulates SCF assembly and O2-de

294 ergoes polyubiquitin-mediated degradation in Dictyostelium, whereas human H-Ras and a Dictyostelium H

295 monstrate conservation of these phenomena in Dictyostelium which has three single-copy H3 variant gen

296 ogical significance of this CP antagonist in Dictyostelium, which expresses a V-1 homolog that we sho

297 We have identified protein NE81 in Dictyostelium, which has properties that justify its den

298 l resistance induces bleb-driven movement in Dictyostelium, which is chemotactic and controlled throu

299 A primary example is the social amoeba Dictyostelium, which migrates to the source of traveling

300 Global stimulation of Dictyostelium with different chemoattractants elicits mu