ライフサイエンスコーパス: Diels

1 Diels-Alder cycloadditions of 3-oxobut-1-enyl substitute

2 Diels-Alder reactions employing 1,2-azaborine heterocycl

3 ing advantage of the decarbonylative [4 + 2] Diels-Alder cycloaddition reaction between ethynyl and t

4 The utility of this monomer in the [4 + 2] Diels-Alder cycloaddition to produce well-defined, sulfo

5 tone, which may proceed as a concerted [4+2] Diels-Alder reaction or a stepwise [6+4] cycloaddition f

6 Cycloadditions, such as the [4+2] Diels-Alder reaction to form six-membered rings, are amo

7 molecular versions of this tridehydro (-3H2) Diels-Alder reaction support a concerted mechanism for t

8 hat undergoes a wide range of reactions as a Diels-Alder diene, dienophile, and [2 + 2] addend.

9 lallene exhibits exceptional reactivity as a Diels-Alder reaction partner and engages in [4 + 2] cycl

10 ggests that the enzyme SpnF does behave as a Diels-Alderase.

11 ce of a natural enzyme evolved to catalyze a Diels-Alder reaction and shows how catalysis is achieved

12 fully closed complex are able to catalyze a Diels-Alder reaction between cyclopentadiene and methyl

13 tions quantitatively reproduce the KIEs in a Diels-Alder reaction and a catalytic glycosylation.

14 he presence of light with suitable enes in a Diels-Alder reaction and undergoes a transformation into

15 ab initio calculations, which suggest that a Diels-Alder-type reaction may be involved with an allyl

16 e 1 forms a unique covalent adduct through a Diels-Alder cycloaddition of three of its anthracene lig

17 lene were successfully synthesized through a Diels-Alder/oxidative cyclodehydrogenation approach.

18 e C70 derivative were synthesized by using a Diels-Alder cycloaddition followed by an addition-elimin

19 nthesis of 2,2'-bis(naphthoquinones) using a Diels-Alder reaction of conjugated ketene silyl acetals

20 Using a Diels-Alder reaction, an anthracene unit with four funct

21 rgoes post-assembly modification (PAM) via a Diels-Alder cycloaddition of the anthracene panels of th

22 This reaction sequence proceeds via a Diels-Alder cycloaddition reaction catalyzed by dimethyl

23 en participate in a second stage acylnitroso Diels-Alder cycloaddition.

24 via a Lewis acid catalyzed retro-Diels-Alder/Diels-Alder sequence, rather than bond rotation in an in

25 process sometimes dominates over the allowed Diels-Alder reaction.

26 as achieved via an intramolecular amidofuran Diels-Alder cycloaddition/rearrangement followed by an i

27 eimides are used, maleimide deprotection and Diels-Alder cycloaddition can be simultaneously carried

28 he competition between self-dimerization and Diels-Alder cycloaddition with an external dienophile us

29 and stereoselective domino Pauson-Khand and Diels-Alder cycloaddition catalyzed by [RhCl(CO)2]2 unde

30 een the recently proposed bis-pericyclic and Diels-Alder routes is blurred, and favorable transition

31 ch as Langmuir-Hinshelwood, Eley-Rideal, and Diels-Alder might be operating during the formation of P

32 strate new observations on catalytic aqueous Diels-Alder and Michael reactions in heterogeneous fashi

33 ]anthracene (4) that involves a tandem aryne Diels-Alder cycloaddition-deoxygenation strategy.

34 cycloalkylidenecarbenes, were intercepted as Diels-Alder adducts.

35 ioselectivity of different reactions such as Diels-Alder cycloadditions or Bingel-Hirsch reactions.

36 anocatalyst for iminium-ion based asymmetric Diels-Alder (DA) reactions has been rationally designed.

37 the polyol chain, a Ti-catalyzed asymmetric Diels-Alder reaction to generate the cis-decalin skeleto

38 citric acid delivers the products of an aza-Diels-Alder (Povarov) reaction with high endo-selectivit

39 Thermal asymmetric aza-Diels-Alder reactions also proceeded in good yields and

40 ne catalysis, asymmetric three-component aza-Diels-Alder reactions of 5-, 6-, and 7-membered cyclic k

41 atalytic enantioselective intramolecular aza-Diels-Alder reactions.

42 photoredox catalysis of radical cation based Diels-Alder cycloadditions mediated by the first-row tra

43 These reactions lead to bicyclic Diels-Alder adducts that spontaneously lose N2.

44 A key biomimetic Diels-Alder dimerization was found to occur at ambient t

45 with terminal alkynes yield products of both Diels-Alder and [2 + 2] cycloaddition.

46 with two ester substituents were prepared by Diels-Alder cycloadditions of cyclopentadiene with dimet

47 luable for the fusion of additional rings by Diels-Alder reactions.

48 events successive reactions of the silole by Diels-Alder dimerization, thus enabling the clean gas-ph

49 te that cucurbit[7]uril (CB[7]) can catalyse Diels-Alder reactions for a number of substituted and un

50 cture a perfect molecular vessel to catalyze Diels-Alder reactions of 9-hydroxymethylanthracene with

51 used for an asymmetric Lewis acid catalyzed Diels-Alder reaction.

52 ms of recently reported Lewis acid-catalyzed Diels-Alder reactions of arylallenes and acrylates were

53 at for models proposed for related catalyzed Diels-Alder reactions.

54 btained by the intermolecular radical cation Diels-Alder (RCDA) reaction.

55 on pathway suggest that a stepwise, cationic Diels-Alder cycloaddition is operative.

56 In the classic Diels-Alder [4 + 2] cycloaddition reaction, the overall

57 For example, in the classic Diels-Alder reaction, butadiene and ethylene combine to

58 15COC identical withCR) for use in classical Diels-Alder (DA) reactions (with 1,3-cyclopentadiene).

59 reaction flow in water, while the classical Diels-Alder mechanism contributes only approximately 17%

60 revealed two competing pathways, a concerted Diels-Alder reaction and a stepwise Michael addition, fo

61 rgy barrier of 22 kcal/mol for the concerted Diels-Alder process and provide no evidence of a competi

62 In both cases the corresponding Diels-Alder adducts between these reagents and the edge

63 imethylbutadiene to afford the corresponding Diels-Alder products.

64 o synthetic gain in a cascade cross-coupling/Diels-Alder reaction, delivering borylated or non-boryla

65 reactions as 2pi or 4pi components (covering Diels-Alder and 1,3-dipolar cycloadditions).

66 oligonucleotides were either cycloadditions (Diels-Alder, Cu(I)-catalyzed azide-alkyne) or the same M

67 precursors via an oxidative dearomatization/Diels-Alder cascade that may have biogenetic relevance.

68 f hydromorphone by oxidative dearomatization/Diels-Alder cycloaddition was investigated.

69 Although intramolecular dehydro-Diels-Alder (IMDDA) reactions have previously been emplo

70 eory (M06-2X) studies of a series of dehydro-Diels-Alder (DDA) reactions.

71 essfully prepared by using the photo-dehydro-Diels-Alder (DDA) reaction, access to (1,7)naphthalenoph

72 ia the bioorthogonal inverse electron demand Diels-Alder (IEDDA) cycloaddition, was developed.

73 The emerging inverse electron demand Diels-Alder (IEDDA) reaction stands out from other bioor

74 addition (SPAAC) and inverse electron demand Diels-Alder (iEDDA) reactions, have become increasingly

75 sent work reports an inverse electron demand Diels-Alder (iEDDA)-type reaction to synthesize 1,3,5-tr

76 clopropene-tetrazine inverse electron demand Diels-Alder cycloaddition reactions.

77 gy predicated on the inverse electron demand Diels-Alder reaction as well as the use of this approach

78 ond formations (e.g. inverse electron demand Diels-Alder reaction) between the tumour bound antibody

79 to catalysis of the inverse electron demand Diels-Alder reactions of heterocyclic azadienes has been

80 on by exploiting the inverse electron demand Diels-Alder reactivity of the tetrazine.

81 However, the inverse electron-demand Diels-Alder (DAinv) reaction between tetrazine (Tz) and

82 and efficient PAM by inverse electron-demand Diels-Alder (IEDDA) reactions.

83 al thiylation and/or inverse electron-demand Diels-Alder addition to residual functional groups withi

84 philic thiol-yne and inverse electron-demand Diels-Alder additions to independently create two interp

85 the strain-promoted inverse electron-demand Diels-Alder cycloaddition, that is, tetrazine ligation,

86 h was employed in an inverse-electron-demand Diels-Alder reaction for heterobiaryl synthesis.

87 zines by means of an inverse-electron-demand Diels-Alder reaction.

88 tepwise mechanism of inverse electron-demand Diels-Alder reactions of 1,2,3-triazines, and that these

89 These inverse electron-demand Diels-Alder reactions of triazines have wide application

90 lopentadiene and the inverse electron-demand Diels-Alder reactions with 3,6-bis(trifluoromethyl)tetra

91 The normal electron-demand Diels-Alder reactions with cyclopentadiene and the inver

92 ners with alkenes in inverse-electron-demand Diels-Alder reactions.

93 a modestly active, computationally designed Diels-Alderase was converted into the most proficient bi

94 A is described employing diastereoselective Diels-Alder and selenocyclization reactions, starting fr

95 , biomimetic total synthesis of the dimeric, Diels-Alder natural product griffipavixanthone from a re

96 We further report that double Diels-Alder reactions under solvent-free condition provi

97 We demonstrate a C-F bond driven Diels-Alder reaction of a fluorinated dienophile and a b

98 nthetic sequence features a highly effective Diels-Alder reaction using a carbamate-substituted silox

99 lysts capable of unlocking new and efficient Diels-Alder reactions would have major impact.

100 s, iminium precursor 22a underwent efficient Diels-Alder cycloaddition with a range of simple and com

101 ugh a highly diastereo- and enantioselective Diels-Alder/lactonization organocascade that generates c

102 ough this study is a highly enantioselective Diels-Alder reaction of a versatile cyclic carbamate sil

103 Few examples of oximino ether Diels-Alder reactions have been reported previously, and

104 celerate disfavored enolate addition and exo Diels-Alder reactions enantioselectively.

105 ridge in one step, and a stereoselective exo-Diels-Alder reaction to form the 6-membered ring.

106 A first Diels-Alder condensation followed by a Stille cross-coup

107 Asymmetric syntheses of the flavonoid Diels-Alder natural products sanggenons C and O have bee

108 Yamamoto-type cyclization followed by 6-fold Diels-Alder cycloaddition, C216 was obtained by oxidativ

109 with a cyclopropene moiety were designed for Diels-Alder reactions with inverse electron demand, and

110 ous esters and amides are classic dienes for Diels-Alder reactions.

111 hat is trapped with 3 equiv of furan to form Diels-Alder tris-adduct 3.

112 ediates subsequently undergo either a formal Diels-Alder cycloaddition or a competitive Michael addit

113 ation-dimerization sequence to afford formal Diels-Alder adducts that undergo a smooth gold-catalyzed

114 erminus experimentally leads to three formal Diels-Alder (DA) cycloaddition products, two of which (i

115 ic, enantioselective prototropic shift/furan Diels-Alder (IMDAF) cascade to construct the ACD tricycl

116 oevenagel condensation/intramolecular hetero Diels-Alder reaction using O-(arylpropynyloxy)-salicylal

117 s likely arise from an intramolecular hetero Diels-Alder reaction.

118 f aziridines and alkenes, and [4 + 2] hetero-Diels-Alder cycloaddition of aldehydes with dienes.

119 ormed through a one-pot sequence of a hetero-Diels-Alder reaction, an oxidative carbon-hydrogen bond

120 The domino aldol/hetero-Diels-Alder synthesis of some new tricyclic pyrano[3,4-c

121 clization sequence over the alternate hetero-Diels-Alder cycloaddition reaction.

122 tions: intramolecular Diels-Alder and hetero-Diels-Alder reactions via a single ambimodal transition

123 azadiene in metal-free base-assisted hetero-Diels-Alder reaction is exploited to quickly assemble an

124 ntramolecular inverse electron-demand hetero-Diels-Alder reaction followed by air oxidation to furnis

125 ereoselective inverse electron demand hetero-Diels-Alder reaction of beta,gamma-unsaturated alpha-ket

126 ntioselective inverse-electron-demand hetero-Diels-Alder reaction of the remote olefin functionality

127 sing a tandem inverse-electron-demand hetero-Diels-Alder/oxa-Michael reaction catalyzed by modularly

128 for yne-enone cyclizations via formal hetero-Diels-Alder reactions.

129 gy involving the hemiaminal formation/hetero-Diels-Alder reaction affords the bicyclic products in a

130 alpha-ketothioesters participating in hetero-Diels-Alder reaction has remained unexplored.

131 an oxa-6pi electrocyclic ring-opening/hetero-Diels-Alder pericyclic cascade.

132 an sp(2) boron substituent, a one-pot hetero-Diels-Alder/ring contraction cascade occurred to afford

133 ocyclic carbene (NHC)-catalyzed redox hetero-Diels-Alder reactions with azolium enolates generated fr

134 actions on-water, is a regioselective hetero-Diels-Alder cycloaddition reaction of enol ethers to 4-p

135 The reaction proceeds via a tandem hetero-Diels-Alder cycloaddition of N,N'-bis(benzenesulfonyl)su

136 ective Bronsted acid catalysts of the hetero-Diels-Alder reaction of a wide variety of aldehydes and

137 comprising three reactions: (1) hexadehydro-Diels-Alder (for aryne generation), (2) intramolecular a

138 mechanism of the intramolecular hexadehydro-Diels-Alder (HDDA) reaction, validated against prior and

139 ree steps by capitalizing on the hexadehydro-Diels-Alder (HDDA) cycloisomerization reaction in which

140 ere experiments showing that the hexadehydro-Diels-Alder (HDDA) cycloisomerization reaction proceeds

141 We demonstrate that the hexadehydro-Diels-Alder (HDDA) cycloisomerization reaction to produc

142 zynes thermally generated by the hexadehydro-Diels-Alder (HDDA) cycloisomerization.

143 d and stepwise mechanisms of the hexadehydro-Diels-Alder (HDDA) reaction are competitive with activat

144 Here we report the use of the hexadehydro-Diels-Alder (HDDA) reaction for the de novo construction

145 ow that benzynes produced by the hexadehydro-Diels-Alder (HDDA) reaction react with many secondary me

146 s with benzynes generated by the hexadehydro-Diels-Alder (HDDA) reaction.

147 s-Alder (TDDA) and by six in the hexadehydro-Diels-Alder (HDDA) reactions.

148 e, and their 1-aza- and 2-aza-derivatives in Diels-Alder reactions with ethylene and fumaronitrile we

149 urated N-acyl iminium ions as dienophiles in Diels-Alder reactions and electrophilic alkylating agent

150 The reactivity of macrocyclic bis-enones in Diels-Alder reactions was examined using quantum chemica

151 The replacement of CH with N increases Diels-Alder reactivity due not only to the more favorabl

152 nts engage diverse dienophiles in an initial Diels-Alder or metal-catalyzed [4 + 2] cycloaddition, tr

153 azaoctane structures using an intermolecular Diels-Alder cycloaddition between a pyrazinone and comme

154 A stereoselective intermolecular Diels-Alder cycloaddition of an intermediate pyrazinone

155 from (+)-citronellal using an intramolecular Diels-Alder reaction as the key step.

156 By taking advantage of an intramolecular Diels-Alder reaction, we have developed a prodrug strate

157 acylation step followed by an intramolecular Diels-Alder reaction.

158 ith those for bimolecular and intramolecular Diels-Alder reactions in order to investigate the contro

159 ohydrate-templated asymmetric intramolecular Diels-Alder reaction of a masked o-benzoquinone (MOB) 9

160 ding a chiral amine-catalyzed intramolecular Diels-Alder reaction to afford 22 in excellent diastereo

161 vergent course of the central intramolecular Diels-Alder reaction, which is dependent on the nature o

162 lective, susbtrate-controlled intramolecular Diels-Alder reaction, a transannular enolate alkylation,

163 d a highly diastereoselective intramolecular Diels-Alder reaction of the formed ene-diene to generate

164 a highly diastereoselective, intramolecular Diels-Alder reaction of a silicon-tethered acrylate; an

165 nd several Lewis acid induced intramolecular Diels-Alder reactions remained fruitless, dialkylaluminu

166 raints on the organocatalyzed intramolecular Diels-Alder reaction to form the isobenzofuran core of t

167 s established by a late-stage intramolecular Diels-Alder cyclization catalyzed by Me2AlCl or La(OTf)3

168 was completed by a late-stage intramolecular Diels-Alder furan (IMDAF) cycloaddition to install the i

169 (2) a highly stereoselective intramolecular Diels-Alder (IMDA) reaction of the camphanate-containing

170 dimerization cascade and the intramolecular Diels-Alder cascade.

171 The intramolecular Diels-Alder reaction has been used as a powerful method

172 An approach to the intramolecular Diels-Alder reaction has led to a cascade synthesis of c

173 carbohydrate template in the intramolecular Diels-Alder reaction of MOBs were revised.

174 sting enzymatic examples (the intramolecular Diels-Alder reaction, and the Cope and the Claisen rearr

175 rk can be constructed through intramolecular Diels-Alder reactions of propiolate-derived enynes follo

176 e pericyclic transformations: intramolecular Diels-Alder and hetero-Diels-Alder reactions via a singl

177 Nitrofurans undergo intramolecular Diels-Alder reactions with tethered electron-poor dienop

178 rough a common biomimetic strategy involving Diels-Alder reactions of unusual double diene containing

179 n-deficient dienophiles undergo irreversible Diels-Alder reactions, a reversible Diels-Alder reaction

180 the absence of enzymatic catalysis (that is, Diels-Alderase activity) in the cycloaddition and strong

181 is of wickerol A (1) that is based on a Jung Diels-Alder reaction, an intramolecular alkylation to co

182 NH4OAc mediated domino Knoevenagel/Diels-Alder cyclocondensation of beta-ketosulfones 1 and

183 nic species which can be used to effect many Diels-Alder reactions in >95% yield and >95% ee using ca

184 As a key-step, a chiral auxiliary-mediated Diels-Alder cycloaddition was developed, introducing the

185 dihydrocatechol in inter- or intra-molecular Diels-Alder reactions.

186 and synthetic procedures involving multiple Diels-Alder reactions under harsh extended reaction cond

187 lerate and control organic reactions, namely Diels-Alder reaction, Claisen rearrangement, and Cope-ty

188 by mimicking the mode of action of a natural Diels-Alderase.

189 enzyme shown here to be a bona fide natural Diels-Alderase.

190 on of product inhibition observed in natural Diels-Alderase enzymes, and pave the way toward the deve

191 compound, five of which used a thermal, net Diels-Alder [4+2] cycloaddition and dehydration at 110 d

192 The discovery of new Diels-Alder cycloaddition/dehydration routes and experim

193 phosphoric acid-catalyzed asymmetric nitroso-Diels-Alder reaction of nitrosoarenes with carbamate-die

194 ecies in situ, which were trapped in nitroso-Diels-Alder (NDA) reactions with various dienes to affor

195 regioselectivity of the noncatalyzed nitroso-Diels-Alder reaction.

196 lished through the one-pot oxidative nitroso-Diels-Alder reaction of N-arylhydroxylamines with diene

197 The previously observed Diels-Alder reactions of arynes with arene were not obse

198 odal and leads directly to both the observed Diels-Alder and an unobserved [6+4] cycloadduct.

199 ifying the complexity-increasing benefits of Diels-Alder and metal-catalyzed cycloadditions.

200 The activation energy of Diels-Alder reactions correlates very well with reaction

201 d nonstatistical effects on the lifetimes of Diels-Alder intermediates.

202 The mechanisms of Diels-Alder reactions between 1,2,3-triazines and enamin

203 astereoselective inverse electron demand oxa-Diels-Alder reactions of resorcinarene ortho-quinone met

204 are presumably formed through an initial oxa-Diels-Alder reaction, followed by an elimination of amin

205 r pericyclic reactions, including the parent Diels-Alder cycloaddition of butadiene with ethylene, el

206 ew cycloisomerization process a pentadehydro-Diels-Alder (PDDA) reaction-a nomenclature chosen for ch

207 rmed through an intramolecular photochemical Diels-Alder reaction.

208 rring the catalytic architecture of possible Diels-Alderases.

209 xt]-cyclases have been reported as potential Diels-Alderases; however, whether their catalytic cycles

210 We intercepted a pre-Diels-Alder intermediate in lovastatin synthesis for the

211 An intramolecular strain-promoted Diels-Alder methylenecyclopropane (IMDAMC) reaction prov

212 degree of oxidation of naphthazarin quinone Diels-Alder adduct 10 is additionally demonstrated and e

213 ver-mediated [3,3]-sigmatropic rearrangement/Diels-Alder reaction of 1,9-dien-4-yne esters is describ

214 d, in which the key step is a regioselective Diels-Alder reaction between a pyranobenzoquinone dienop

215 te centered upon a late-stage regioselective Diels-Alder reaction.

216 retro-Diels-Alder reaction of its adduct with N-benzylpyrrole

217 imination of bromo-ethylmalonate and a retro-Diels-Alder cycloaddition reaction.

218 istry on the rate of force-accelerated retro-Diels-Alder reactions of furan/maleimide adducts.

219 e small-molecule cargo was achieved by retro-Diels-Alder cleavage of an oxanorbornadiene linkage, pre

220 ucts of which undergo fragmentation by retro-Diels-Alder reaction at rates that vary with the substit

221 tems occurs via a Lewis acid catalyzed retro-Diels-Alder/Diels-Alder sequence, rather than bond rotat

222 bicyclic gamma-butyrolactones via the retro-Diels-Alder reaction/intramolecular conjugate ene cascad

223 at generated by the NIR light induce reverse Diels-Alder reactions.

224 versible Diels-Alder reactions, a reversible Diels-Alder reaction with the less electron-deficient me

225 d thermodynamic parameters of the reversible Diels-Alder reaction between 1,2-azaborines and methyl a

226 o dienyl sulfoxides undergo highly selective Diels-Alder cycloadditions with N-phenylmaleimide with r

227 Sequential Diels-Alder reactions on a tautomerized naphthazarin cor

228 methylfuran in situ, and the obtained stable Diels-Alder adducts were subjected to the series of furt

229 Upon tandem Diels-Alder reactions with several symmetrical as well a

230 ed by, for example, four in the tetradehydro-Diels-Alder (TDDA) and by six in the hexadehydro-Diels-A

231 The Diels-Alder chemistry of these new dendralenes (as multi

232 The Diels-Alder dimer of cyclopentadiene carboxylate, Thiele

233 The Diels-Alder reaction between 1 and 6 occurs under the se

234 The Diels-Alder reaction between 2-methylfuran and 3-bromobe

235 The Diels-Alder reaction enables introduction of new functio

236 The Diels-Alder reaction is a cornerstone of modern organic

237 The Diels-Alder reaction is one of the most common methods t

238 The Diels-Alder reaction represents one of the most thorough

239 The Diels-Alder reaction, a [4 + 2] cycloaddition of a conju

240 The Diels-Alder reactions between 2 equiv of (E,E)-1,4-bis(4

241 The Diels-Alder reactions of cyclopentadiene, cyclohexadiene

242 The Diels-Alder reactivities of a series of cycloalkenes, fr

243 The Diels-Alder reactivity of C59NH azafullerene has been ex

244 The Diels-Alder step was studied by density functional theor

245 The Diels-Alder substrate is built up in an efficient manner

246 Although the Diels-Alder reaction has long been utilized for the prep

247 Both are produced by the Diels-Alder condensation of hexachlorocyclopentadiene wi

248 rbaldehyde motif that is inaccessible by the Diels-Alder cycloaddition.

249 ly remendable polymer was synthesized by the Diels-Alder reaction between dithienylfuran and maleimid

250 ver the furan is a key step facilitating the Diels-Alder and dehydration reactions in the acid sites

251 an-containing CPP precursor was used for the Diels-Alder reaction with the parent benzyne or 3,6-dime

252 The activation free energies for the Diels-Alder reactions of cyclic 1-azadienes are 10-14 kc

253 The physical factors governing the Diels-Alder reactivity of (2,7)pyrenophanes have been co

254 The origins of chirality transfer in the Diels-Alder reaction using chiral arylallenes are uncove

255 with the distortion of the reactants in the Diels-Alder reactions are nearly identical and that the

256 reactivities and stereoselectivities in the Diels-Alder reactions of substituted cyclopropenes with

257 vities of alkenes compared to alkynes in the Diels-Alder reactions with tetrazines arise from the dif

258 leads to smaller distortion energies in the Diels-Alder transition states.

259 currently proposed mechanisms (including the Diels-Alder one) for this reaction in water (as a first-

260 The key steps involve the Diels-Alder cycloaddition of cyclopent-2-en-1-one to the

261 ed with the gas phase, the enzyme lowers the Diels-Alder barrier significantly, consistent with exper

262 The use of the Diels-Alder adduct of alpha-terpinene and maleic anhydri

263 Manipulation of the Diels-Alder adducts provides the desired geometrically d

264 -catalyzed intramolecular cyclization of the Diels-Alder adducts was identified for the efficient for

265 he subsequent reductive deoxygenation of the Diels-Alder adducts with Fe2(CO)9 followed by oxidative

266 asymmetric Lewis-acid organocatalysis of the Diels-Alder cycloaddition of cyclopentadiene to cinnamat

267 A case study of the Diels-Alder cycloaddition of cyclopentadiene with ethyle

268 ificant decrease in selectivity/yield of the Diels-Alder dehydration product is observed.

269 ht (>435 nm) "gate" the reversibility of the Diels-Alder reaction and turn the self-healing propertie

270 Herein, we review the application of the Diels-Alder reaction of quinones in the total synthesis

271 The distortion energy of the Diels-Alder reaction transition states mostly arises fro

272 ibutes to the enhancement of the rate of the Diels-Alder reaction.

273 e reactivity and endo/exo selectivity of the Diels-Alder reactions involving 1,2-azaborines have been

274 ining framework tin (Sn-Beta) to produce the Diels-Alder dehydration product, 4-(hydroxymethyl)benzoi

275 Third, the superoxide species reduces the Diels-Alder cycloadduct radical cation to the final prod

276 anic chemist engaged in total synthesis, the Diels-Alder reaction is among the most powerful and well

277 d with free energy simulations show that the Diels-Alder pathway is favored in the enzyme environment

278 Thus, calculations predict that the Diels-Alder reaction is privileged in the case of ethyl

279 It is observed that the Diels-Alder reaction only displays high diastereoselecti

280 these products with a dienophile through the Diels-Alder reaction confirmed the formation of vitamin

281 ne, because they are predistorted toward the Diels-Alder transition structures.

282 acenes are attached to this module using the Diels-Alder reaction, which also forms one of the acene

283 ins uncertain if any of them proceed via the Diels-Alder mechanism.

284 dicate that the barriers associated with the Diels-Alder reactions of ethyl nitrosoacrylate are over

285 Thermal Diels-Alder reactions of alpha-amido acrylates with N-Cb

286 utational investigations revealed that these Diels-Alder reactions proceed via transition state struc

287 s were performed on a set of 13 transannular Diels-Alder (TADA) reactions with 10-18-membered rings.

288 esis of spinosyn A, catalyzes a transannular Diels-Alder reaction.

289 t molecule featured a novel bis-transannular Diels-Alder reaction that casted stereoselectively the d

290 equisite for a successful diene transmissive Diels-Alder (DTDA) reaction by employing two different d

291 SpnF enzyme, one of the most promising "true Diels-Alderase" candidates.

292 in a single synthetic step that includes two Diels-Alder additions, two decarbonylations, and two deh

293 d kidamycinone were achieved by means of two Diels-Alder reactions.

294 ry susceptibility of [5]radialene to undergo Diels-Alder dimerization/polymerization.

295 dravine, respectively, were found to undergo Diels-Alder reactions to afford mixtures of regioisomeri

296 mily of chiral dienophiles for the venerable Diels-Alder (DA) cycloaddition.

297 Aromatics are formed via Diels-Alder cycloaddition with ethylene, which is produc

298 g between phosphors and polymer matrices via Diels-Alder click chemistry is devised as a method.

299 ough an iterative reaction sequence, wherein Diels-Alder reactions and a subsequent aromatization aff

300 egiocontrolled "click-unclick" oxazole-ynone Diels-Alder cycloaddition/cycloreversion and ensuing 2-a