ライフサイエンスコーパス: E-box element

1 s, were found with germline deletions of the E-box element.

2 ocyte target promoter despite binding to its E-box element.

3 regulation of APEG-1 transcription via this E-box element.

4 pression of reporter plasmids containing the E-box element.

5 peat SRE-1 or to a palindromic high-affinity E-box element.

6 activation of specific target genes through E box elements.

7 rs directed to the PER and CRY promoters via E-box elements.

8 required the activation of neuronal promoter E-box elements.

9 oter; this reduction was dependent on intact E-box elements.

10 The Cugbp1 promoter contains three E-box elements.

11 anscriptional control of MuRF1 via conserved E-box elements.

12 sterol regulatory element (SRE), and double E-Box elements.

13 equences but not those with mutations in the E-box elements.

14 ell as relief of repression through distinct E-box elements.

15 cally, is capable of binding to both Inr and E-box elements.

16 x but contained a TATA box and AP1, AP2, and E-box elements.

17 xpression by binding to DNA at enhancer-box (E-box) elements 5-CACGTG-3.

18 L1 heterodimers activated transcription from E-box elements, a type of transcription factor-binding s

19 vate the hGH1 promoter, and mutation of this E-box element adversely affected basal activity after ge

20 Here, we show that a conserved E-box element also contributes to control in the islet a

21 uman BMAL1/MOP4 heterodimers bound the AANAT E box element and enhanced transcription.

22 differentiation and enhances its binding to E box elements and transcriptional activity.

23 r deletion analysis, we have mapped a distal E-box element and a proximal Ikaros site that are essent

24 nimal hTERT promoter contains Myc-responsive E-box elements and recent studies have suggested a role

25 It binds with high affinity to E-box elements and, through interaction with coactivator

26 ssion: 1) CpG methylation of the core of the E-box element, and 2) binding of a distinct protein comp

27 The enhancer contains two E-box elements, and one FTZ-F1 nuclear hormone receptor

28 ned TATA and CCAAT boxes; Sp1, AP1, AP2, and E-box elements; and erythrocyte-specific CACCC and Krupp

29 vates MTA1 transcription through a conserved E-box element at its promoter.

30 rect c-Myc target; it contains two consensus E-box elements, both of which bind c-Myc.Max heterodimer

31 her affinity than its interaction with other E-box elements (CANNTG).

32 rt the identification of a Ca(2+)-responsive E-box element, CaRE2, within BDNF promoter III that bind

33 romoter activity, while the proximal GAS and E box elements contribute to the IFN-gamma inducibility

34 olutionarily conserved and overlaps with the E-Box element critical for BMAL1/CLOCK binding and its t

35 ed hTERT promoter fragments, we show that an E-box element downstream of the transcription initiation

36 ABF-1 is capable of binding an E-box element either as a homodimer or as a heterodimer

37 oter, the mutations in either the SRE or the E-Box elements eliminated the response to FFAs.

38 in DNA of the FT gene that possesses various E-box elements except G box.

39 the mouse OSCAR gene contains two potential E-box elements for microphthalmia transcription factor (

40 emonstrated that the betaGK and insulin gene E-box elements formed the same cell-enriched (BETA2:E47)

41 The E-box elements had a minimal role in E-cadherin transcri

42 expression of cathepsin B by binding to the E box element in the cathepsin B promoter as a repressor

43 ion of the hTERT promoter was dependent upon E box elements in the core promoter.

44 al cells is controlled by two well-conserved E box elements in the large first intron.

45 wist transcriptional repressors that bind to E box elements in the TNF promoter and suppress NF-kappa

46 in a STAT3-independent manner, requiring an E-box element in the CCL2 promoter to mediate transcript

47 ecific transcription factor HNF-3beta and an E-box element in the distal enhancer adjacent to an NF-k

48 gulating HP1gamma by directly binding to the E-box element in the first intron of HP1gamma gene, and

49 Both c-Myc and NeuroD can bind the E-box element in the insulin promoter, but unlike NeuroD

50 Previously, we identified an E-box element in the mouse APEG-1 proximal promoter, whi

51 zed by measuring their ability to bind to an E-box element in the NEUROD1 promoter in vitro and to in

52 romised the ability of NEUROG3 to bind to an E-box element in the NEUROD1 promoter.

53 athway that augments binding of c-Myc to key E-box elements in the AEG-1 promoter, thereby regulating

54 aEF1 increased enhancer activity of upstream E-box elements in the Col1a2 gene.

55 crophthalmia transcription factor, acting at E-box elements in the Ctsk promoter.

56 E-box elements in the E-cadherin promoter were found to

57 gnaling induces Snail, which binds conserved E-box elements in the PGDH promoter to repress transcrip

58 Taken together, the data indicate the E-box elements in the proximal E-cadherin promoter are c

59 ial occupancy of c-Myc and Prx1 complexes at E-box elements in the prx5 gene proximal promoter.

60 is suggested that rUSF1s, which bind to two E-box elements in the SP-A gene 5'-flanking region, may

61 ptional activation by c-Myc through specific E box elements is thought to be essential for its biolog

62 The results clearly show that the E-box element is not the SREBP recognition site in this

63 This E-box element is required for maximum activity of the AT

64 ory factor(s) interaction with the canonical E-box element located within the alphaBC promotor.

65 c-Myc/Max heterodimers bind to canonical E-box elements located in the bax promoter region as dem

66 We now report that a distal E-box element, located between bp -309 and -314 upstream

67 This E-box element mediated repression of hTERT transcription

68 iR-210-Mnt pathways caused c-Myc to bind the E-box element of cyclin D1, instead of Mnt, resulting in

69 Nuclear binding activity of Myc to the E-box element of p53 and cyclin D1 increased, whereas th

70 te IA-1 gene expression through the proximal E-box element of the IA-1 promoter.

71 anscription in vivo through both Inr and the E-box elements of the adenovirus major late promoter.

72 Twist bound to E-box elements on AKT2 promoter and enhanced its transcr

73 moter analyses demonstrate that the proximal E box element serves as a myogenin binding site and is b

74 c-finger transcription factors known to bind E-box elements, SLUG and SNAIL, repressed E-cadherin-dri

75 ranscription factor binding sites, including E-box elements that are consensus Myc binding sites, as

76 ter regions of both genes, we identified two E-box elements that work in conjunction to activate tran

77 omoter sequences revealed an enhancer motif (E-box) element that binds the circadian transcriptional

78 tiple TATA and CCAAT boxes and Sp1, AP1, and E-box elements; the exon 1 promoter lacked a CCAAT box b

79 CLK-CYC directly bind E box elements to activate transcription, but the mechan

80 -like sequences cooperate with the canonical E-box element to promote high-amplitude transcription, w

81 bind the hGH1 promoter region containing the E-box element was confirmed in the hGH1 transgenic mouse

82 reporters containing non-glucose-responsive E box elements were not activated by ChREBP-Mlx expressi

83 carbohydrate response and sterol-responsive (E-box) elements were present in the Mstn promoter and we

84 Mist1 also is capable of binding to E-box elements when complexed as a heterodimer with the

85 In addition, a group of E-box elements, which are Myc binding sites, confer resp

86 We demonstrate that the E-box elements, which we show can function as Myc-respon

87 that bind to and activate expression from an E-box element within its enhancer.

88 e findings indicate that by interacting with E-box elements within the promoter, MYCN can upregulate