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1  all E2F family members tested (E2F1 through E2F5).
2 e 34 (Cdc34) and E2F transcription factor 5 (E2F5).
3  cyclin D1 and cdk4, pcna, cyclin G, Rb, and E2F5.
4 0 almost exclusively associate with E2F4 and E2F5.
5 TR sequences complementary to either E2F1 or E2F5.
6 ts by forming a ternary complex with E2f4 or E2f5 and Dp1 that binds and activates most of the genes
7 A crystal structure of the p107 CTD bound to E2F5 and its dimer partner DP1 reveals the molecular bas
8 o other kinases, transcription factors E2F4, E2F5, and p130, a DNA repair gene, a gene for the signal
9                               Thus, E2F4 and E2F5 are dispensable for cell cycle progression but nece
10 e growth factor (NGF), while E2F1, E2F3, and E2F5 are downregulated.
11    miRNA target databases predicted E2F1 and E2F5 as putative targets.
12 affects the binding of E2F2, E2F3, E2F4, and E2F5 but significantly inhibits the binding of E2F1.
13                                     E2F4 and E2F5 constitute a defined subset of the family.
14 at LMP1 also blocks the function of E2F4 and E2F5 (E2F4/5) transcription factors through promoting th
15 E2F2, and E2F3a) or repressors (E2F3b, E2F4, E2F5, E2F6, and E2F7).
16          Interaction between NS1 and E2F4 or E2F5 enhanced the nuclear import of these repressive E2F
17 her, this leads to the activation of E2F1 to E2F5, enhanced expression of E2F-responsive genes, and i
18 y viral factor responsible for altering E2F1-E2F5 expression, but not E2F6-E2F8 expression.
19 ts the control of expression of the E2F4 and E2F5 genes.
20 t that simultaneous inactivation of E2F4 and E2F5 in mice results in neonatal lethality, suggesting t
21  repressing a network of oncogenes including E2F5, LIN28B, MYC and NRAS.
22 get genes related to cell mitosis and cycle, E2f5, Npm1, Cenpb, Rbbp6, and Scyl1, expressed in the he
23 ng to p130 but had no effect on E2F4/p107 or E2F5/p130 complexes.
24 shift with the antibody against the E2F4 and E2F5 pocket protein, p107.
25 f miR-205 in melanoma cells reduced E2F1 and E2F5 protein levels.
26                     But, unlike the E2F4 and E2F5 proteins, which are also expressed in quiescent cel
27                              Downstream E2F4/E2F5 targets, which are potentially involved in the prog
28 a lesser extent E2F1, E2F3, and occasionally E2F5), was constitutively maintained at high levels inde
29            The expression levels of E2F1 and E2F5 were correlated inversely with that of miR-205 in m
30   Accordingly, E2F1 to E2F3 but not E2F4 and E2F5 were found to bind sp1 in vitro.
31 sent in E2F2 and E2F3 but absent in E2F4 and E2F5, were essential.
32 rminal activation domains of E2F1, E2F4, and E2F5, when fused to the Gal4 DNA binding domain, are suf
33                     In humans, Rb binds E2F1-E2F5, whereas p107 and p130 almost exclusively associate
34 reporter assays and the transcription factor E2f5, which regulates CSF production, was verified as a

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