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1 ccompanied by abundant expression of the HPV E4 protein.
2 hat this activity is specific to full-length E4 protein.
3 protein colocalized in the nucleus with the E4 protein.
4 division induced by coexpression of the two E4 proteins.
5 ion in infected cells requires viral E1B and E4 proteins.
6 by abundant expression of the full-length E1;E4 protein (17-kDa) and smaller E4 polypeptides (16-, 11
8 r cysteine protease calpain cleaves the 16E1^E4 protein after amino acid 17 to generate species that
9 er, coexpression of the full-length E1(wedge)E4 protein and the truncated E4-16K protein inhibited no
14 thesize that differential expression of HPV1 E4 proteins during the viral life cycle determines the h
15 e progressively cleaved from the full-length E4 protein (E1(wedge)E4) of 17 kDa to produce a series o
16 eplacement of arginine 45 in the full-length E4 protein (E1;E4), implying that these two HPV1 E4 func
17 tions in E4 indicated that the E1(circumflex)E4 protein-encoding requirements for these various proce
18 n primate and baby hamster kidney cells, the E4 protein failed to direct the E1B protein to the nucle
19 udy, we further analyzed the interactions of E4 proteins from different adenovirus serotypes with the
20 identified, but we had previously shown that E4 proteins from diverse papillomaviruses interact with
22 ntify the role(s) of the viral E1(circumflex)E4 protein in the HPV life cycle, we characterized the p
25 man papillomavirus (HPV) type 16 E1^E4 (16E1^E4) protein is expressed in the middle to upper layers o
28 c cleavage-of the human papillomavirus (HPV) E4 protein occurs as the infected keratinocytes migrate
34 rotein synthesis inhibited, a portion of the E4 protein present in the REF-52 nuclei migrated to the
36 ild-type Ad type 5 (Ad5) infections, E1b and E4 proteins target the cellular DNA repair protein Mre11
39 ser scanning microscopy, indicated that this E4 protein was located predominantly within the cytoplas
40 t HPV protein expressed in this phase is the E4 protein, we do not fully understand the role of this
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