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1 ccompanied by abundant expression of the HPV E4 protein.
2 hat this activity is specific to full-length E4 protein.
3  protein colocalized in the nucleus with the E4 protein.
4  division induced by coexpression of the two E4 proteins.
5 ion in infected cells requires viral E1B and E4 proteins.
6 by abundant expression of the full-length E1;E4 protein (17-kDa) and smaller E4 polypeptides (16-, 11
7          When expressed by transfection, the E4 protein accumulated in the nucleus.
8 r cysteine protease calpain cleaves the 16E1^E4 protein after amino acid 17 to generate species that
9 er, coexpression of the full-length E1(wedge)E4 protein and the truncated E4-16K protein inhibited no
10                                Since E2a and E4 proteins are essential for efficient Ad DNA amplifica
11                           The cleavage of E1^E4 proteins by calpain may be a common strategy used by
12                               Apolipoprotein E4 protein colocalizes with oligomeric amyloid-beta and
13            Also, different forms of the HPV1 E4 protein cooperate to negatively influence keratinocyt
14 thesize that differential expression of HPV1 E4 proteins during the viral life cycle determines the h
15 e progressively cleaved from the full-length E4 protein (E1(wedge)E4) of 17 kDa to produce a series o
16 eplacement of arginine 45 in the full-length E4 protein (E1;E4), implying that these two HPV1 E4 func
17 tions in E4 indicated that the E1(circumflex)E4 protein-encoding requirements for these various proce
18 n primate and baby hamster kidney cells, the E4 protein failed to direct the E1B protein to the nucle
19 udy, we further analyzed the interactions of E4 proteins from different adenovirus serotypes with the
20 identified, but we had previously shown that E4 proteins from diverse papillomaviruses interact with
21 cytoplasmic E1B protein colocalized with the E4 protein in both human and rat cell nuclei.
22 ntify the role(s) of the viral E1(circumflex)E4 protein in the HPV life cycle, we characterized the p
23                 We report here that the HPV1 E4 protein, in the presence of a soluble form of the rep
24           Human papillomavirus type 1 (HPV1) E4 protein is associated with cytoplasmic and nuclear in
25 man papillomavirus (HPV) type 16 E1^E4 (16E1^E4) protein is expressed in the middle to upper layers o
26                      Here, we show that HPV1 E4 proteins mediate inhibition of cell division by more
27 is that proteolytic cleavage of the E1(wedge)E4 protein modifies its function.
28 c cleavage-of the human papillomavirus (HPV) E4 protein occurs as the infected keratinocytes migrate
29  SRPK1 is a common binding partner of the E1^E4 protein of diverse human papillomavirus types.
30 ys 42% identity to amino acids 85-115 of the E4 protein of type 75 human papilloma virus.
31 es the functional interaction of the E1B and E4 proteins of adenovirus.
32 RX-009 expresses E4ORF3, a representative Ad E4 protein, only in colon cancer cell lines.
33      Our results indicate that the HPV31 E1--E4 protein plays a significant role in promoting HPV gen
34 rotein synthesis inhibited, a portion of the E4 protein present in the REF-52 nuclei migrated to the
35 nantly a cytoplasmic variant GFP or a GFP-E1 E4 protein, respectively.
36 ild-type Ad type 5 (Ad5) infections, E1b and E4 proteins target the cellular DNA repair protein Mre11
37  cells, in which we also found E1(circumflex)E4 protein to be expressed at low levels.
38                          This failure of the E4 protein to direct the nuclear localization of the E1B
39 ser scanning microscopy, indicated that this E4 protein was located predominantly within the cytoplas
40 t HPV protein expressed in this phase is the E4 protein, we do not fully understand the role of this
41                       Apolipoproteins E3 and E4, proteins with a molecular mass of 34.15 kDa, differ

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