ライフサイエンスコーパス: EAR

1 EAR increases expression of exopolysaccharide genes and

2 EAR prioritization identified multiple sites, biological

3 EAR was significantly reduced after 4 weeks (DeltaFEV1 2

4 person-years; SIR, 1.97 [95% CI, 1.86-2.08]; EAR, 85.3 [95% CI, 76.2-94.8] per 100,000 person-years),

5 SK2190915 vs. placebo for the minimum FEV(1) EAR was 0.408 L (0.205, 0.611).

6 binds strongly, in addition to HNF-4, ARP-1, EAR-2, and EAR-3, heterodimers of RXRalpha with RARalpha

7 t four orphan/nuclear receptors, ERRalpha-1, EAR-2, COUP-TFI (EAR-3), and RARgamma, bind to the silen

8 person-years (SIR, 2.10 [95% CI, 2.06-2.14]; EAR, 719.3 [95% CI, 693.3-745.6] per 100,000 person-year

9 -1, and other positive clones include EAR-2, EAR-3 (COUP-TF1), RAR gamma, and p120E4F.

10 son-years; SIR, 11.56 [95% CI, 10.83-12.33]; EAR, 109.6 [95% CI, 102.0-117.6] per 100,000 person-year

11 nhancer of aerial rosette (on chromosome 4): EAR has been tentatively identified as a new allele of t

12 as highest for hypopharyngeal SCC (SIR, 3.5; EAR, 307.1 per 10,000 PYR) and lowest for laryngeal SCC

13 PYR) and lowest for laryngeal SCC (SIR, 1.9; EAR, 147.8 per 10,000 PYR).

14 person-years; SIR, 7.54 [95% CI, 7.17-7.93]; EAR, 168.3 [95% CI, 158.6-178.4] per 100,000 person-year

15 person-years; SIR, 4.65 [95% CI, 4.32-4.99]; EAR, 76.1 [95% CI, 69.3-83.3] per 100,000 person-years).

16 axin-1 (CCL11) secreted enzymatically active EARs (EC(50) 5 nM) by piecemeal degranulation.

17 ved in the secretion of enzymatically active EARs following chemokine stimulation.

18 4, and the secretion of enzymatically active EARs was detected using an RNase activity assay.

19 he other containing LAZY1, which contains an EAR motif, and promotes vertical shoot growth in Oryza s

20 dations for dietary reference values, ie, an EAR (median) and RDA (97.5th percentile) for healthy adu

21 Based on an EAR of 100 mg/d of vitamin C, the RDA is proposed to be

22 of thyroidal iodine stores would produce an EAR of 72 mug and a recommended dietary allowance of 80

23 omen [725 nmol (320 microg)/d] to provide an EAR of 1178 nmol (520 microg)/d.

24 which was shown previously to bind ARP-1 and EAR-3 but not HNF-4, binds strongly heterodimers of RXRa

25 to bind HNF-4, also binds strongly ARP-1 and EAR-3, as well as RXRalpha/RARalpha heterodimers and les

26 gly, in addition to HNF-4, ARP-1, EAR-2, and EAR-3, heterodimers of RXRalpha with RARalpha, and less

27 T, aerial rosette gene (on chromosome 5) and EAR, enhancer of aerial rosette (on chromosome 4): EAR h

28 mineral intake, but contributions to AI and EAR for iron, zinc and calcium were very low (5-20%, 10-

29 rifies that the F(L) estimation equation and EAR to EAR(c) conversion methods are appropriate.

30 which is required for nuclear retention, and EAR-like domain, which participates in nuclear export, a

31 s at the 3-5 mm bud stages, with the SAD and EAR gene products detected in 4-7 mm buds.

32 and the corresponding gene products SAD and EAR were detected by Western blotting in 3-4 mm buds, co

33 mechanisms of mouse eosinophil secretion and EAR release, we combined an RNase assay of mouse EARs wi

34 e element since ERRalpha-1 is expressed, but EAR-2 and RARgamma are only present in a small number of

35 novel Bacillus subtilis riboregulator called EAR that shares structural complexity with riboswitches

36 rical EAR can be transformed into a circular EAR(c) that is convenient to use in two-dimensional enco

37 d by a novel cis-acting RNA element, coined 'EAR', located between the second and third gene of the e

38 o 1 of 3 dietary vitamin D targets (control; EAR: 400 IU/d; or RDA: 600 IU/d) for 12 wk (January to A

39 octogenarian women suggest that the current EAR and RDA for elderly women may be underestimated.

40 ue, although the 95% CI includes the current EAR.

41 [median (IQR): control, 227 (184-305) IU/d; EAR, 410 (363-516) IU/d; and RDA, 554 (493-653) IU/d; P

42 This receptor, HaPiT2 (formerly designated EAR), in contrast to the human form of the A-MuLV recept

43 osely related to JAZ8 and includes divergent EAR, TIFY/ZIM, and Jas motifs.

44 The discovery of a large number of divergent EARs suggests the intriguing possibility that these prot

45 s to determine the time course of the early (EAR) and late allergic reaction (LAR).

46 O1 target genes, DAZ1 and DAZ2, which encode EAR motif-containing C2H2-type zinc finger proteins.

47 By contrast, expression of ERF6-EAR, in which ERF6 was fused to the ERF-associated amphi

48 , leading to hypersusceptibility of the ERF6-EAR transgenic plants to B. cinerea.

49 Following EAR, imaging studies are used to identify leaks since pa

50 are identified as late as 7 years following EAR.

51 beta2 integrins were found to be crucial for EAR secretion, and we suggest a mechanism in which sprea

52 chanism in which spreading is obligatory for EAR secretion.

53 t model, single i.p. injections of g-E and g-EAR delayed bioluminescence from metastasizing ES-2-luc

54 espectively, despite fast drug release for g-EAR in vivo versus in vitro.

55 After i.p. injection in mice, g-EAR showed gelation in the peritoneum and sustained, loc

56 ng of 17-AAG (Hsp90) and rapamycin (mTOR) (g-EAR).

57 ation results of hearing function from the G-EAR consortium and TwinsUK were used for meta-analysis.

58 in transgenic plants by different Cys2/His2 EAR-containing proteins, is mediated by the EAR-domain.

59 opharyngeal SCC (annual percentage change in EAR, -4.6%; P = .03).

60 In EARs, FEV1 and Feno value decreases reached 36.8% and 22

61 R alpha-1, and other positive clones include EAR-2, EAR-3 (COUP-TF1), RAR gamma, and p120E4F.

62 d secreted their granule proteins, including EAR and eosinophil peroxidase in response to CCL11.

63 ncentrations (control: 55.8 +/- 12.3 nmol/L; EAR: 64.1 +/- 10.0 nmol/L; and RDA: 63.7 +/- 12.4 nmol/L

64 The median EAR was estimated as the median of this distribution, 10

65 We found that secretion of mouse EARs in response to CCL11 and CCL24 was Galphai -depende

66 release, we combined an RNase assay of mouse EARs with ultrastructural studies.

67 te that Arabidopsis CDF proteins contain non-EAR motif-like conserved domains required for interactio

68 at a time, very low calcium intake (<60% of EAR), very low 25(OH)D (<12 ng/mL), and elevated PTH (>6

69 emales, receive more than the 70% and 90% of EAR value of vitamin C, respectively.

70 Endoleak is a common complication of EAR that can lead to aneurysm enlargement and even ruptu

71 In this study, the interaction of EAR-2, COUP-TFI, and RARgamma with S1 was confirmed by D

72 cation, terminal phenotype, and reduction of EAR protein levels.

73 demonstrate chemokine-dependent secretion of EARs from both intact mouse eosinophils and their cell-f

74 cationic protein, and their murine ortholog EARs, which have been shown to be involved in host defen

75 promoted rapid diversification of paralogous EAR genes in both primates and rodents.

76 at the antipathogen functions of the primate EARs are conserved after they are established and that t

77 The effective attraction radius (EAR) of an attractive pheromone-baited trap was defined

78 used to calculate exposure-activity ratios (EARs) as a prioritization tool.

79 ever, the signal transduction that regulates EARs secretion in response to physiological stimuli, suc

80 ifferent areas (endemics-area relationships, EARs) should be used instead of SARs, and that SAR-based

81 dovascular abdominal aortic aneurysm repair (EAR) requires long-term surveillance for endoleak or inc

82 erved ERF-associated amphiphilic repression (EAR) motif at the carboxy terminus abolishes BZR1's abil

83 o the ERF-associated amphiphilic repression (EAR) motif, strongly suppresses B. cinerea-induced defen

84 TOR (ERF)-associated amphiphilic repression (EAR) motif.

85 ns an ERF-associated amphiphilic repression (EAR) motif.

86 ng factor-associated amphiphilic repression (EAR-like) domain.

87 PL/TPR co-repressors, whereas the repressive EAR domain is dispensable and the acidic domain seems on

88 nd women, the Estimated Average Requirement (EAR) and Recommended Dietary Allowance (RDA) for protein

89 The Estimated Average Requirement (EAR) and Recommended Dietary Allowance (RDA) for vitamin

90 n the current Estimated Average Requirement (EAR) for adults of 0.66 g . kg(-)(1) . d(-)(1) based on

91 at least the Estimated Average Requirement (EAR) for folate from foods alone.

92 pment, but no estimated average requirement (EAR) is available for this age group.

93 The estimated average requirement (EAR) is the amount of nutrient estimated to meet the req

94 not meet the Estimated Average Requirement (EAR) of 400 IU/d.

95 The median estimated average requirement (EAR) of nitrogen from these data was 105 mg N x kg(-1) x

96 on to use the Estimated Average Requirement (EAR) rather than the Recommended Dietary Allowance (RDA)

97 y to meet the Estimated Average Requirement (EAR) than were nonusers.

98 ake below the Estimated Average Requirement (EAR), and only 21% had a vitamin D intake that met or ex

99 e values -the Estimated Average Requirement (EAR), RDA, Adequate Intake (AI), and a tolerable Upper L

100 women, or the estimated average requirement (EAR).

101 ly 30% of the estimated average requirement (EAR).

102 take (AI) and estimated average requirement (EAR).

103 [<60% of the Estimated Average Requirement (EAR)] or insufficient 25-hydroxyvitamin D [25(OH)D] (<20

104 from estimated average protein requirements (EAR) weighted by population age structure.

105 re below the Estimated Average Requirements (EARs) for 10-15% of the women.

106 w respective estimated average requirements (EARs) or exceeded 99th percentiles of usual intakes of t

107 ent inhibition of the early airway response (EAR) to antigen.

108 associated with the early allergic response (EAR).

109 attenuation of the early asthmatic response (EAR) by GSK2190915; treatment difference of GSK2190915 v

110 n the development of early airway responses (EAR), LAR and AHR in allergic sheep undergoing airway ch

111 (VI) on early and late asthmatic responses (EAR/LAR) and airway hyper-responsiveness (AHR).

112 were measured during early airway responses (EARs) and late airway responses after challenge with hou

113 mmalian eosinophil-associated ribonucleases (EARs), which are members of the ribonuclease A superfami

114 cidence ratios (SIRs), excess absolute risk (EAR) per 10,000 person-years at risk (PYR), and number n

115 nce ratios (SIRs) and excess absolute risks (EARs) assessing relative and absolute cancer risk in tra

116 udogenes of the eosinophil-associated RNase (EAR) family from 5 rodent species.

117 d secretion of eosinophil-associated RNases (EARs), such as the human eosinophilic cationic protein (

118 oteins are the eosinophil-associated RNases (EARs): the human eosinophil-derived neurotoxin and eosin

119 primary physiological function of the rodent EARs.

120 Since EAR-2, COUP-TFI, and RARgamma are expressed at high leve

121 e EAR and F(L) were used to obtain a smaller EAR(c) for use in a two-dimensional model that caught an

122 Under the same conditions, a spherical EAR was placed at the center of the 10-m layer and inter

123 The spherical EAR can be transformed into a circular EAR(c) that is co

124 presses transcription through its C-terminal EAR motif.

125 A conserved C-terminal EAR-like motif found in IGT genes was required for these

126 lear receptors, ERRalpha-1, EAR-2, COUP-TFI (EAR-3), and RARgamma, bind to the silencer (S1) region o

127 These findings show that EAR repression domains in a subgroup of JAZ proteins rep

128 The EAR and F(L) were used to obtain a smaller EAR(c) for us

129 The EAR for a particular attractant and insect species in na

130 The EAR motif in BZR1 mediates recruitment of TPL to BZR1-re

131 The EAR repression domain was required for MYBH-regulated le

132 The EAR was derived by adding the DFE of this quantity [454

133 The EAR(c) equation requires an estimate of the effective th

134 Eight hours after the EAR, FEV1 was still decreased (P < .001), whereas Feno v

135 tumor was 2.2 (95% CI, 2.1 to 2.2), and the EAR was 167.7 cancers per 10,000 PYR.

136 ntified putative interactors of Zat7 and the EAR-domain, including WRKY70 and HASTY, a protein involv

137 y blocked the LAR and AHR and attenuated the EAR phase.

138 y), and most had intakes that were below the EAR for vitamins E (82%) and D (74%).

139 ated for pulmonary functions during both the EAR and late allergic response, and airway hyperresponsi

140 EAR-containing proteins, is mediated by the EAR-domain.

141 type zinc finger proteins, which contain the EAR transcriptional repressor domain, are thought to pla

142 ent intake for individuals; in contrast, the EAR has only a 50% probability of adequacy.

143 In contrast, the EAR-motif appears not to be involved in suppressing the

144 Prioritized bioactivities from the EAR analysis were linked to discrete adverse outcome pat

145 FF/VI provides additive protection from the EAR relative to its components, significant protection o

146 We also identify the EAR element in other species within the order Bacillales

147 If the EAR cannot be determined, an adequate intake (AI) amount

148 Ninety-six percent of children in the EAR and RDA groups and 67% of the control group had 25(O

149 No changes were observed in the EAR, BAL fluid IL-4 levels, or serum total and Ag-specif

150 kes of most US children aged 1-13 y meet the EAR.

151 microg) DFE/d was derived by multiplying the EAR by 1.2 to account for an estimated 10% CV.

152 The presence of the EAR element within the eps operon is required for readth

153 nt discovery that the gene repertoire of the EAR family is much larger in rodents than in primates ha

154 ity between the evolutionary patterns of the EAR genes and those of the major histocompatibility comp

155 Our study demonstrates key roles of the EAR motif and TPL in BR regulation of gene expression an

156 with DU1-29 also reduced the severity of the EAR to antigen.

157 The inhibition of the EAR with one of the inhibitors, TBC-1269, was associated

158 A deletion or a mutation of the EAR-motif of Zat7 abolishes salinity tolerance without a

159 This study assessed the effect of age on the EAR and RDA for protein.

160 preference for using the RDA rather than the EAR for the DVs: 1) consumers are likely to expect that

161 tandard for nutrient intake, rather than the EAR, has a potential benefit (a higher prevalence of ade

162 40% of females has an intake higher than the EAR.

163 e of adults with usual intakes less than the EAR.

164 research studies available suggest that the EAR and RDA might be greater than the assumed 0.66 and 0

165 these observations, we hypothesize that the EAR element associates with RNA polymerase to promote pr

166 We also find that the EAR element promotes readthrough of heterologous termina

167 Our findings demonstrate that the EAR-domain of Cys2/His2-type zinc finger proteins plays

168 These results demonstrate that the EAR-motif of Zat7 is directly involved in enhancing the

169 r JAZ proteins, recruits TOPLESS through the EAR motif-containing adaptor protein NINJA.

170 The canola MYB80 was fused to the EAR (ERF-associated amphiphilic repression) repressor an

171 is quantity [454 nmol (200 microg)/d] to the EAR for nonpregnant women [725 nmol (320 microg)/d] to p

172 ese defects are rescued by TPL fusion to the EAR motif-mutated BZR1.

173 to provide a DNA-binding module fused to the EAR-repression domain (SRDX) to generate a chimeric repr

174 abiotic stress, it is not clear whether the EAR-motif of these proteins is involved in this function

175 hether vitamin D intakes consistent with the EAR or Recommended Dietary Allowance (RDA), through fort

176 At 12 wk, the EAR and RDA groups had significantly higher vitamin D in

177 y of the women had dietary intakes below the EARs for iron (97%), vitamin D (96%), and folate (70%).

178 contributed to the diversification of these EAR genes.

179 that the F(L) estimation equation and EAR to EAR(c) conversion methods are appropriate.

180 CR3-mediated signaling pathway that leads to EAR secretion in both mouse and human eosinophils.

181 ining nonspecific DNA-binding domain and two EAR motifs typically found in repressors of stress-induc

182 ent sequences of 2417 nucleotides at the two EAR loci, the eosinophil-derived neurotoxin (EDN, RNase

183 We demonstrate that the two EAR motifs in DAZ1/DAZ2 mediate their function in the ma

184 mediated repression depends on an LxLxL-type EAR (for ERF-associated amphiphilic repression) motif at

185 Data on 220 patients undergoing EAR were retrospectively reviewed.

186 A total of 52 patients (24%) who underwent EAR had endoleak detected during postoperative follow-up

187 While it is unclear whether EAR senses a biofilm-inducing signal, the results sugges

188 of eosinophil-associated diseases, in which EARs are key factors.

189 an equivalent number of insects as that with EAR in three dimensions.