ライフサイエンスコーパス: EG-VEGF

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1 EG-VEGF also increased the phosphorylation of Akt in a p

2 EG-VEGF expression in normal ovaries is dynamic and gene

3 EG-VEGF is an example of a class of highly specific mito

4 EG-VEGF led to a time- and dose-dependent phosphorylatio

5 Therefore, Bv8 and EG-VEGF, along with other factors such as VEGF-A, may ma

6 duction in the PPFs angiopoietin-2, HGF, and EG-VEGF provides potential insight into the multifactori

7 Both EG-VEGF and VEGF resulted in extensive angiogenesis and

8 These findings indicate that both EG-VEGF and VEGF are expressed in PCOS ovaries, but in d

9 xide synthase in ACE cells was stimulated by EG-VEGF with a time course correlated to the Akt phospho

10 Consistent with such an effect, EG-VEGF was a potent survival factor for ACE cells.

11 -derived vascular endothelial growth factor (EG-VEGF) has been recently identified as a mitogen speci

12 -derived vascular endothelial growth factor (EG-VEGF), induced proliferation, migration and fenestrat

13 -derived vascular endothelial growth factor (EG-VEGF), with selective activity for endothelial cells

14 However, EG-VEGF had little or no effect on a variety of other en

15 Expression of human EG-VEGF messenger RNA is restricted to the steroidogenic

16 Like EG-VEGF, Bv8 is able to induce proliferation, survival a

17 lpha(i) plays an important role in mediating EG-VEGF-induced activation of MAPK signaling.

18 present study, we compared the expression of EG-VEGF and VEGF mRNA in a series of 13 human PCOS and 1

19 PCOS ovaries, we found strong expression of EG-VEGF mRNA in theca interna and stroma in most of the

20 A particularly high expression of EG-VEGF was detected in the Leydig-like hilus cells foun

21 aracterization of the signal transduction of EG-VEGF in a responsive cell type, bovine adrenal cortex

22 Systemic in vivo exposure to Bv8 or EG-VEGF resulted in significant increases in total leuko

23 Adenoviral delivery of Bv8 or EG-VEGF to the mouse testis resulted in a potent angioge

24 Bv8, or EG-VEGF that shares the same receptors, increased number

25 We have previously shown that the related EG-VEGF and Bv8 proteins, also known as prokineticin 1 (

26 Our data demonstrate that EG-VEGF, possibly through binding to a G-protein coupled

27 h proliferation and migration in response to EG-VEGF.

28 Unlike EG-VEGF, Bv8 is expressed in the bone marrow.

29 Bv8 and endocrine-gland-derived VEGF (EG-VEGF), or prokineticins, are two highly related, secr

30 = 0.31, P = .02), and endocrine gland-VEGF (EG-VEGF, r = 0.43, P < .001).

31 Similar to VEGF, EG-VEGF possesses a HIF-1 binding site, and its expressi

32 However, unlike VEGF, EG-VEGF failed to promote angiogenesis in the cornea or

33 shares 60% identity and 75% similarity with EG-VEGF.

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