ライフサイエンスコーパス: EPC

1 EPC counts (CD34/KDR) after 24 months were defined as pr

2 EPC cultures issued from embryos that expressed only wil

3 EPC may indeed provide significant clinical protection a

4 EPC measurements in a small sample size were suggestive

5 EPC stimulates transcription factors such as Nrf-1 and h

6 EPC's showed significant reduction in WT hyperoxic group

7 EPCs (CD45(dim)/CD34(+)/kinase domain receptor(+)) from

8 EPCs and CTCE represent important potential therapeutic

9 EPCs decreased significantly at 1 year in the placebo gr

10 EPCs from Lewis rats exhibited a strong capacity to form

11 EPCs regulate the angiogenic switch via paracrine secret

12 EPCs were independently enumerated using ARCA and FACS w

13 EPCs were injected intravenously into Lewis rats with ar

14 EPCs were isolated from the long bones of Wistar rat bon

15 forming cells (ECFCs) were the most abundant EPC subtype in kidneys, but were not detected in blood o

16 GSK3beta activity contributes to accelerated EPC cellular senescence, an effect reversed by small mol

17 Mice were subjected to CLP and administered EPCs at varying doses, CTCE, or a combination of the two

18 e hypothesized that exogenously administered EPCs are also beneficial in CLP sepsis and that CTCE pro

19 , suppression of miR-10A* and miR-21 in aged EPCs increased Hmga2 expression, rejuvenated EPCs, resul

20 .0001), neovascularization (P = 0.0028), and EPC recruitment (P = 0.0059).

21 /-) mice developed acellular capillaries and EPC dysfunction similar to the DBA/STZ/WD mice.

22 n the BM, and rescued defective LKS cell and EPC mobilization.

23 27, 0.76 and 3.7mA/M/cm(2), while CA, EC and EPC electrode with BQ showed 25, 25, and 60mA/M/cm(2) of

24 41, 47 and 53microW/cm(2), while CA, EC and EPC electrodes with BQ showed 260, 330 and 500microW/cm(

25 densities of biofuel cells using CA, EC and EPC electrodes without BQ were 41, 47 and 53microW/cm(2)

26 CA, EC and EPC of POx on CNTs were used to fabricate enzymatic elec

27 sensor, the sensitivities of the CA, EC, and EPC electrodes without BQ were measured to be 0.27, 0.76

28 e electrodes were prepared using CA, EC, and EPC samples.

29 vitro effect of CTCE on miRNA expression and EPC function were determined.

30 d concentrations, impaired EPC migration and EPC/BM-HC proliferation through a PPARgamma-mediated STA

31 ently recover the known amount of EC-MVs and EPC-MVs from particle-depleted plasma, and to detect the

32 T5 content is crucial for gene targeting and EPC fate.

33 analysis and biomarker discovery of ECs- and EPCs- derived MVs.

34 HMVECs and EPCs from human cord blood were also examined for CXCR6

35 Additionally, HMVECs and EPCs responded to CXCL16 stimulation, but exhibited uniq

36 y activity (toward both isolated kinases and EPCs) remained almost untouched and comparable to the ac

37 r, co-culture of BMP2 gene-modified MSCs and EPCs dramatically increased osteoblast differentiation o

38 and that BMP2 gene modification for MSCs and EPCs dramatically promotes bone regeneration.

39 ne) and BMP2 genetically-engineered MSCs and EPCs in a rat critical-sized (8 mm) caviarial bone defec

40 combination of BMP2 gene -modified MSCs and EPCs in nCS/A dramatically increased the new bone and va

41 sults demonstrated that delivery of MSCs and EPCs with the injectable nCS/A scaffold did not affect c

42 the large nonstructural protein NS1 arrested EPCs at a cell cycle status with a 4 N DNA content, whic

43 row-derived endothelial progenitor cells (BM-EPCs).

44 (TNFR) signaling in RBR was evaluated in BM-EPCs from WT, TNFR1/p55KO, and TNFR2/p75KO mice, in vitr

45 post-IR, indicating a significant RBR in BM-EPCs in vivo.

46 NFR2 signaling may prevent delayed RBR in BM-EPCs, conceivably, in bone marrow milieu in general.

47 F-TNFR2 signaling may induce RBR in naive BM-EPCs and that blocking TNF-TNFR2 signaling may prevent d

48 IR conditioned media (CM) of WT and p55KO BM-EPCs largely abolished RBR in both cell types.

49 Full body gamma-IR WT BM-EPCs showed a biphasic response: slow decay of p-H2AX fo

50 essed on ischemic tissue endothelium and BMD-EPC act as double-locks to secure targeted EPC- endothel

51 o induce ischemic tissue endothelium and BMD-EPC to express both E-selectin and its ligands.

52 n and homing of bone marrow-derived EPC (BMD-EPC).

53 findings describe a novel mechanism for BMD-EPC homing and indicate that dual E-selectin/ligand pair

54 Indeed, both EPCs and ECs treated with high glucose (25 mmol/L) in th

55 n a randomized trial, early palliative care (EPC) in patients with metastatic non-small-cell lung can

56 n adheres to epithelioma papillosum of carp (EPC) cells 3 to 5 times more extensively than the wild-t

57 ung EPCs suppressed Hmga2 expression, caused EPC senescence, as evidenced by senescence-associated be

58 METHOD AND RESULTS: Mouse Lin-Sca1(+)CD31(+) EPCs and human CD34(+) cells were treated with inhibitor

59 hat 1) anti-CD105 (EC marker) and anti-CD34 (EPC marker) conjugated-microbeads had the highest sensit

60 ations affected endothelial progenitor cell (EPC) and bone marrow-derived hematopoietic cell (BM-HC)

61 Endothelial progenitor cell (EPC) counts are proposed surrogate markers for vascular

62 We used enteric progenitor cell (EPC) cultures and mice to study the roles of these prote

63 MVEC) and human endothelial progenitor cell (EPC) recruitment into engrafted human synovium that was

64 larization, and endothelial progenitor cell (EPC) recruitment.

65 ) that promotes endothelial progenitor cell (EPC)-mediated neurovascular remodeling during stroke rec

66 (LKS) cell and endothelial progenitor cell (EPC; CD34(+)Flk1(+)) mobilization, and vascular recovery

67 Endothelial progenitor cells (EPC) are able to migrate to tumor vasculature.

68 marrow-derived endothelial progenitor cells (EPC) contribute to the angiogenesis-dependent growth of

69 ic efficacy of endothelial progenitor cells (EPC) from patients with DM.

70 Homing of endothelial progenitor cells (EPC) to the ischemic tissues is a key event in neovascul

71 Endothelial progenitor cells (EPC) were successfully cultured on L-AME functionalized

72 ted protein in endothelial progenitor cells (EPC).

73 marrow-derived endothelial progenitor cells (EPC).

74 blood-derived endothelial progenitor cells (EPCs) and bone marrow-derived mesenchymal stem cells (MS

75 bservations on endothelial progenitor cells (EPCs) and endothelial cells (ECs).

76 of circulating endothelial progenitor cells (EPCs) and plasma levels of proangiogenic vascular endoth

77 Cs), including endothelial progenitor cells (EPCs) are biologically related to many aspects of cardio

78 d functions of endothelial progenitor cells (EPCs) are increased in patients with acute myocardial in

79 Endothelial progenitor cells (EPCs) are present in the systemic circulation and home t

80 rse subsets of endothelial progenitor cells (EPCs) are used for the treatment of ischemic diseases in

81 ells (ECs) and endothelial progenitor cells (EPCs) by combining microbeads with fluorescence quantum

82 ld seeded with endothelial progenitor cells (EPCs) can overcome these limitations using an environmen

83 Endothelial progenitor cells (EPCs) contribute to postnatal endothelial repair and reg

84 ified MSCs and endothelial progenitor cells (EPCs) could significantly enhance vascularized bone rege

85 Endothelial progenitor cells (EPCs) enter the systemic circulation in response to cues

86 recruitment of endothelial progenitor cells (EPCs) from the bone marrow to the regenerating vasculatu

87 Endothelial progenitor cells (EPCs) have been associated with human sepsis but their r

88 uced levels of endothelial progenitor cells (EPCs) have been associated with increased cardiovascular

89 tropism to human erythroid progenitor cells (EPCs) in human bone marrow and the fetal liver.

90 corporation of endothelial progenitor cells (EPCs) into microvessels contributes to the vascularizati

91 corporation of endothelial progenitor cells (EPCs) into newly developing blood vessels contributes to

92 properties of endothelial progenitor cells (EPCs) is not known.

93 Endothelial progenitor cells (EPCs) may be relevant contributors to endothelial cell (

94 lls (CPCs) and endothelial progenitor cells (EPCs) PTH, and genetic parameters in RTRs.

95 s signals within erythroid progenitor cells (EPCs) that are essential for red blood cell production.

96 Endothelial progenitor cells (EPCs) was assayed by flow cytometer.

97 Endothelial progenitor cells (EPCs) were cultured on the V-RDDs-anchoring scaffold and

98 Circulating endothelial progenitor cells (EPCs) were quantified at baseline and 1 year.

99 ed to quantify endothelial progenitor cells (EPCs), circulating endothelial cells (CECs), and endothe

100 Endothelial progenitor cells (EPCs), defined as CD34(+)VEGR2(+) using traditional fluo

101 les (EMPs) and endothelial progenitor cells (EPCs), respectively.

102 of circulating endothelial progenitor cells (EPCs), which has been attributed to their defective mobi

103 lial cells and endothelial progenitor cells (EPCs).

104 ition to the generation of endothelial cells/EPCs from pluripotent stem cells, direct reprogramming o

105 gramming of fibroblasts to endothelial cells/EPCs is becoming an important source of regenerative vas

106 This extrapolated point charge (EPC) method assigns effective point charges in a consist

107 Circulating EPC and levels of VEGF, HIF-1alpha and EPO were signific

108 ature serve as docking sites for circulating EPC, which express counterpart E-selectin ligands.

109 Circulating EPCs (CD34(+)/KDR(+)), angiogenic T cells (CD3(+)/CD31(+

110 diseases in clinical trials, and circulating EPCs levels are considered as biomarkers for coronary an

111 Numbers of blood circulating EPCs were assessed by flow cytometry.

112 In parecoxib-treated mice, blood circulating EPCs were higher, but numbers of recruited EPCs in endom

113 ndicate that bone marrow-derived circulating EPCs do not engraft into blood vessels, but that such ci

114 S988A)-expressing mice have more circulating EPCs than their wild-type counterparts.

115 rtery tonometry), and numbers of circulating EPCs and EMPs (by using flow cytometry) were assessed.

116 bunit) that leads to deficits of circulating EPCs and impaired vascular repair, which could be revers

117 tensities on the mobilization of circulating EPCs over 24 hours in women.

118 In vivo, numbers of circulating EPCs were not affected by estrogen.

119 marrow, decreased the number of circulating EPCs, resulting in angiogenesis suppression and impaired

120 GFP(+)/Tie2(+) EPCs, numbers of circulating EPCs, vascularization, cell proliferation, apoptosis, an

121 Synechococcus clades, Eastern Pacific Clade (EPC) 1 and EPC2, were identified.

122 coating (EC) and enzyme precipitate coating (EPC).

123 coating (EC) and enzyme precipitate coating (EPC).

124 e efficient enhancer-promoter communication (EPC); however, the role of chromatin structure and dynam

125 on microscopy and confocal imaging confirmed EPC-matrix adhesion.

126 porting the association between baseline CPC/EPC levels, future cardiovascular events, and death.

127 Overall, reduced CPC/EPC levels were associated with a approximately 2-fold i

128 ies reporting the prognostic role of the CPC/EPC measure on cardiovascular outcomes and death.

129 neity among studies and according to the CPC/EPC phenotype was generally high.

130 In studies of cultured EPCs and mice, we found that control of differentiation

131 We found that culturing EPCs in high glucose media increased adhesion to bone ma

132 ro (using the epithelioma papulosum cyprini [EPC] fish cell line) and in vivo (using rainbow trout fr

133 w the most commonly used protocols to define EPCs by culture assays or by fluorescence-activated cell

134 Zeb2(Delta/+) EPCs had increased neuronal differentiation compared to

135 Overexpression of EDNRB in Zeb2(Delta/+) EPCs restored inhibition of neuronal differentiation, si

136 Incubation of Zeb2(Delta/+) EPCs with EDN3, on the other hand, resulted in only part

137 heterozygous for the mutation (Zeb2(Delta/+) EPCs) were exposed to EDN3; we analyzed the effects on c

138 bilization and homing of bone marrow-derived EPC (BMD-EPC).

139 ons of macroions interacting via the derived EPC effective potential.

140 Bone marrow-derived EPCs were isolated to monitor their in vivo and in vitro

141 Indeed, wild-type-derived EPCs' injection resulted in a significantly higher blood

142 potential, we investigated whether discrete EPC abnormalities were associated with early nonprolifer

143 DM EPCs also exhibited higher levels of GSK3beta activity r

144 and showed 40% less baseline activity in DM EPCs, an effect reversed by GSKi treatment.

145 Administration of DM EPCs reduced the intima-to-media ratio, an effect that w

146 Proteomic profiling of DM EPCs treated with GSKi identified 37 nonredundant, diffe

147 an effect that was further augmented when DM EPCs were pretreated with GSKi yet absent when cathB was

148 insights on how mechanistically d-PA drives EPC/BM-HC dysfunction in diabetes.

149 PC inhibited sCD146 angiogenic effects, i.e. EPC migration, proliferation, and capacity to form capil

150 A from 25 to 60 bp results in more efficient EPC.

151 ke, along with an accumulation of endogenous EPCs.

152 e demonstrated that CTCE recruits endogenous EPCs in septic mice.

153 therapy with an angiogenic tissue-engineered EPC construct.

154 termine if hyperglycemic conditions enhanced EPC adhesion.

155 In in vitro analysis, CTCE enhanced EPC proliferation, angiogenesis, and prosurvival signali

156 These mice also exhibited enhanced EPC migration and restoration of inflammatory and oxidat

157 tion of alcohol consumption, and the ensuing EPC dysfunction, may negatively compete with the benefic

158 ible rare cell identification, can enumerate EPCs in ARMD patients more reliably.

159 e endplate currents (mEPCs) and nerve-evoked EPCs (eEPCs) under voltage-clamp, which, unlike current-

160 othelium interactions by which to facilitate EPC homing and promote neovascularization and tissue rep

161 cell-derived factor (SDF)-1alpha facilitates EPC recruitment and is elevated in murine sepsis models.

162 Patients with DM had fewer EPCs and increased rates of apoptosis.

163 target gene Hmga2 as critical regulators for EPC senescence.

164 D34(+)VEGR2(+) may have predictive value for EPC enumeration in future ARCA studies.

165 Furthermore, EPCs from the transgenic mice exhibited augmented adhesi

166 TEBVs fabricated from HGPS iSMCs and hCB-EPCs show reduced vasoactivity, increased medial wall th

167 od-derived endothelial progenitor cells (hCB-EPCs) from a separate, healthy donor.

168 IH in vitro had similar effects on healthy EPC functions.

169 CXCR6 was prominently expressed on human EPCs and HMVECs, and its expression on HMVECs could be u

170 pothesized that reprogramming mouse or human EPCs, or both, using small molecules targeting key epige

171 In primary human EPCs, shRNA knockdown studies confirmed RHEX regulation

172 Estrogen- and vehicle-treated human EPCs were analyzed for migration and tube formation.

173 To identify EPC changes with biomarker potential, we investigated wh

174 ic and stearic acid concentrations, impaired EPC migration and EPC/BM-HC proliferation through a PPAR

175 19(Arf) expression, and resulted in impaired EPC angiogenesis in vitro and in vivo, resembling EPCs d

176 p16(Ink4a)/p19(Arf) expression, and improved EPC angiogenesis in vitro and in vivo.

177 ential therapeutic intervention in improving EPC-mediated angiogenesis and vascular repair.

178 Silencing angiomotin in EPC inhibited sCD146 angiogenic effects, i.e. EPC migrat

179 ant strain does not replicate efficiently in EPC cells and fails to replicate in J774A.1 macrophages.

180 d RA SF exhibited a significant reduction in EPC recruitment.

181 Reductions in EPC levels do not seem to explain the increased risk of

182 ting cathepsin-induced cleavage of SIRT 1 in EPCs and blunting SIPS and apoptotic cell death induced

183 The change in EPCs from baseline to 6 hours post-exercise was correlat

184 The change in EPCs from baseline was greatest in the 80% group (P < 0.

185 imilar molecular events could be detected in EPCs isolated from type 2 diabetic patients.

186 g tissues and lineages, RHEX was elevated in EPCs, occurred as a plasma membrane protein, was rapidly

187 ceptor for advanced glycation endproducts in EPCs prevents this effect.

188 e experiments using transgenes expression in EPCs from retroviral vectors.

189 miR-126, -125b, -34a, and -155 expression in EPCs.

190 tensities promoting the highest increases in EPCs and angiogenic factors.

191 Moreover, beta2AR stimulation results in EPCs proliferation, migration, and differentiation, enha

192 ived factor (SDF)-1alpha were upregulated in EPCs derived from the transgenic mice, whereas AMPK-medi

193 previously reported that SDF-1alpha-induced EPC homing is mediated by a panel of adhesion molecules

194 as potential mechanisms for exercise-induced EPCs mobilization.

195 , and prosurvival signaling while inhibiting EPC senescence.

196 Median (interquartile range [IQR]) EPC counts at baseline and month 24 were 6 (2-9) and 3 (

197 35a; 2) anti-CD144 (EC marker) and anti-KDR (EPC marker) conjugated-Q-dots exhibited the best sensiti

198 s as compared with not treated or beta2AR KO EPC-treated mice.

199 ion was observed when beta2AR knock out (KO) EPCs were injected.

200 Low EPC levels are associated with a higher risk of subseque

201 wed a similar pattern of significantly lower EPCs but a high percentage of coexpression of OCN.

202 We analyzed the major EPC subtypes in murine kidneys, blood, and spleens after

203 Bone marrow EPCs were analyzed for migratory function and gene expre

204 The mean EPC levels (+/- standard error of the mean) were 1.4 +/-

205 also provide in vivo data that d-PA-mediated EPC dysfunction could be rescued by PPARgamma blockade.

206 d 5 x 10(5) rat osteogenic transformed MSCs (EPC/otMSCs) were fixed to the exposed calvaria.

207 the groups of nCS/A, nCS/A+MSCs, nCS/A+MSCs+EPCs and nCS/A+BMP2 gene-modified MSCs, the combination

208 ro-CT demonstrated that cotransplantation of EPC/otMSCs significantly improved bone formation and min

209 can differentially affect the efficiency of EPC, suggesting that gene regulation over a distance cou

210 serum SDF-1alpha levels and improvements of EPC function and reendothelialization were all abrogated

211 Improved enzyme loading of EPC resulted in 6.5 and 4.5 times higher activity per we

212 h sAS showed significantly higher numbers of EPC-OCN (CD34+/KDR+/OCN+) than controls.

213 re/dynamics and, in turn, affect the rate of EPC in vitro and in silico.

214 positively or negatively affect the rate of EPC, depending upon the length and location of the DNA r

215 p the microRNA/gene expression signatures of EPC senescence, we performed microRNA profiling and micr

216 that precipitation and crosslinking steps of EPC have an important role in maintaining enzyme activit

217 Furthermore, ethanol-mediated suppression of EPC biology was endothelial nitric oxide synthase-depend

218 Suppression of EPC mobilization by PM(2.5) could induce deficits in vas

219 , proliferative and angiogenic capacities of EPCs, angiogenic T-cell numbers, and vascular endothelia

220 n of MSCs and endothelial differentiation of EPCs in vitro.

221 In vitro, exposure of EPCs to ethanol suppressed E2-induced proliferation, sur

222 ce results in reduced number and function of EPCs, potentially contributing to increased cardiac risk

223 educed E2-induced mobilization and homing of EPCs to injured myocardium compared with the E2-alone gr

224 e cell cycle arrest during B19V infection of EPCs, we analyzed the cell cycle change using 5-bromo-2'

225 rogressively decreased circulating levels of EPCs positive for both Flk-1 and Sca-1 (Flk-1(+)/Sca-1(+

226 copy demonstrated a significant migration of EPCs from the construct to the myocardium, suggesting a

227 nin stimulated transendothelial migration of EPCs in a concentration-dependent manner.

228 ontitis is associated with a mobilization of EPCs from the bone marrow, apparently in response to sys

229 trogen significantly increased the number of EPCs incorporated into the lesions' microvasculature, re

230 ish-oil supplementation increased numbers of EPCs and reduced numbers of EMPs relative to those with

231 When subthreshold numbers of EPCs were coadministered with CTCE in CLP mice they syne

232 ificantly suppressed synovial recruitment of EPCs and hyperproliferation of synovial cells.

233 KS activation in the synovial recruitment of EPCs in arthritis, acting via kallikrein activation and

234 study, we investigated the potential role of EPCs in renal EC repair.

235 (CV) risk, but limited data are available on EPC levels in the human immunodeficiency virus (HIV)-inf

236 velopment of therapeutic strategies based on EPC in the treatment of ischemic diseases.

237 conversion to TAC has no favorable effect on EPC.

238 rch avenues to move forward our knowledge on EPC biology.

239 The effect of tacrolimus (TAC) on EPC is unknown.

240 We aimed to evaluate the role of beta2AR on EPCs' function.

241 nalysis showing the expression of beta2AR on EPCs.

242 significant increase of Flk-1 expression on EPCs as assessed by fluorescence-activated cell sorter.

243 cells, tissue-resident endothelial cells or EPCs may primarily drive the restoration of vascular fun

244 ELISA protein profiling of WT and p55KO EPC gamma-IR-CM over 5 days showed significant increases

245 layed RBR (3-5 days) were amplified in p55KO EPCs, suggesting a possible role for TNFR2/p75 signaling

246 mation of p-H2AX foci in nonirradiated p55KO EPCs.

247 BR (1-5 h) were inhibited in p55KO and p75KO EPCs, whereas delayed RBR (3-5 days) were amplified in p

248 dent vasorelaxation, lipoprotein parameters, EPC numbers and function, and neoangiogenesis in lupus-p

249 both hormesis and exercise preconditioning (EPC).

250 ogenic potential was assessed by quantifying EPC cell migration and vascular differentiation.

251 [CNT]) or beta-TCP mixed with 5 x 10(5) rat EPCs and 5 x 10(5) rat osteogenic transformed MSCs (EPC/

252 1); among patients with MDS, those receiving EPC had greater rates of depression response at 12 weeks

253 g EPCs were higher, but numbers of recruited EPCs in endometriotic lesions were significantly lower w

254 ndothelial response, associated with reduced EPCs, and increased PTH in RTRs; the evaluation of endot

255 miR-10A* and miR-21 regulate EPC senescence via suppressing Hmga2 expression and modu

256 med to determine whether microRNAs regulated EPC senescence and, if so, what the underlying mechanism

257 EPCs increased Hmga2 expression, rejuvenated EPCs, resulting in decreased senescence-associated beta-

258 ate differentiation conditions, reprogrammed EPCs showed efficient differentiation into cardiomyocyte

259 lts suggest that epigenetically reprogrammed EPCs display a safe, more plastic phenotype and improve

260 ngiogenesis in vitro and in vivo, resembling EPCs derived from aged mice.

261 >C, 894G>T, and 4a/4b polymorphisms and RHI, EPC, and CPC number was found.

262 Seeded EPCs underwent ex vivo modification with stromal cell-de

263 In coculture studies, EPCs augmented LPS-induced macrophage IL-10 production.

264 D-EPC act as double-locks to secure targeted EPC- endothelium interactions by which to facilitate EPC

265 After 34 days at room temperature, EPC retained 65% of initial activity, while CA and EC ma

266 These results demonstrated that EPCs increase new vascular growth, and that BMP2 gene mo

267 esent study provides the first evidence that EPCs express a functional beta2AR.

268 The EPC number and function did not differ between CAV-negat

269 e cylinder, BV/TV and TMD were higher in the EPC/otMSC group compared with CNT (BV/TV: 22.9% +/- 4.4%

270 he three subregions, BV/TV was higher in the EPC/otMSC group compared with CNT (top: 20.25% +/- 2.4%

271 he effective pair potential and validate the EPC method by comparing molecular dynamics simulations o

272 POx immobilization and stabilization via the EPC approach can lead us to develop continuous glucose m

273 on and the virial pressure obtained with the EPC model.

274 he EPCs migratory activity, and enhanced the EPCs' ability to promote endothelial cell network format

275 increase of cell proliferation, improved the EPCs migratory activity, and enhanced the EPCs' ability

276 Thus, EPCs could become readily accessible informers of vascul

277 th, cyst formation, homing of GFP(+)/Tie2(+) EPCs, numbers of circulating EPCs, vascularization, cell

278 ming of green fluorescent protein(+)/Tie2(+) EPCs, vascularization, cell proliferation, and apoptosis

279 virulence by reducing bacterial adhesion to EPC cells and facilitating intracellular bacterial repli

280 EseJ inhibits bacterial adhesion to EPC cells from within bacterial cells.

281 Patients assigned to EPC had greater improvements in PHQ-9 scores at 12 weeks

282 In vitro, estrogen-treated EPCs exhibited a higher migratory and tube-forming capac

283 deep sequencing of small RNAs revealed tumor EPC-intrinsic miRNAs including miR-10b and miR-196b, whi

284 Two EPC subtypes with different functions have been characte

285 Stimulation of wild-type EPCs with beta-agonist isoproterenol induced a significa

286 The mechanisms underlying EPC senescence are unknown.

287 We measured levels of CD34(+)VEGFR2(+) EPCs suggestive of a trend with higher values in patient

288 Interestingly, CD34(+)VEGR2(+) EPC analysis using FACS did not produce similar results

289 versus 35.7% +/- 4.9%, P = 0.02; CNT versus EPC/otMSC, respectively).

290 60.78 +/- 5.8 mgHA/ccm, P = 0.03; CNT versus EPC/otMSC, respectively).

291 In vivo EPC administration in sepsis increased plasma IL-10, sup

292 onsistent with our in vitro results, in vivo EPCs' treatment resulted in an improvement of impaired a

293 eceptor pair that is closely associated with EPC recruitment and blood vessel formation in the RA joi

294 Survival was improved with EPC therapy at a threshold of 10(6) cells.

295 tors (P=0.04) and positively correlated with EPCs (P=0.04) but not with PTH (P=0.2).

296 Furthermore, this scaffold laden with EPCs promoted neovascularization in an animal model of h

297 erexpression of miR-10A* and miR-21 in young EPCs suppressed Hmga2 expression, caused EPC senescence,

298 When exposed to EDN3, Zeb2(+/+) EPCs continued expression of ZEB2 but did not undergo an

299 ntiation, similar to incubation of Zeb2(+/+) EPCs with EDN3.

300 hat expressed only wild-type Zeb2 (Zeb2(+/+) EPCs) or were heterozygous for the mutation (Zeb2(Delta/