ライフサイエンスコーパス: Env glycoprotein

1 IV-2 isolates, where it is controlled by the Env glycoprotein.

2 with protein and glycan features of the HIV Env glycoprotein.

3 levels as well as fusogenic activity of the Env glycoprotein.

4 lls mediated by cell surface-expressed HIV-1 Env glycoprotein.

5 ions exhibiting unique patterns of processed Env glycoprotein.

6 inactivation of sensitive but not resistant Env glycoproteins.

7 bodies reactive with xenotropic or MCF virus env glycoproteins.

8 ASBP-M(4070A) forms particles containing MLV Env glycoproteins.

9 r stomatitis virus, or murine leukemia virus Env glycoproteins.

10 or immune recognition of the HIV-1 envelope (Env) glycoprotein.

11 unodeficiency virus type 1 (HIV-1) envelope (Env) glycoprotein.

12 iciency virus type 1 (HIV-1) gp120 envelope (Env) glycoprotein.

13 ency virus it is a property of the envelope (Env) glycoprotein.

14 ytoplasmic domains of the relevant envelope (Env) glycoproteins.

15 y and phenotypically diverse SIVsm envelope (Env) glycoproteins.

16 udding even in the presence of the envelope (Env) glycoproteins.

17 ent preparations of oligomeric SIV envelope (Env) glycoproteins.

18 PIV1 from a chimpanzee for the pol, gag, and env glycoprotein 120 (gp120) regions, indicating greater

19 d the binding of ADCC-mediating mAb to HIV-1 Env glycoprotein 120 (gp120).

20 The HIV-1 envelope (Env) glycoprotein, a trimer of gp120-gp41 heterodimers,

21 Structural features of the Env glycoprotein and its enormous variability have frust

22 e the human immunodeficiency virus envelope (Env) glycoprotein and intracellular fusion machines, are

23 in the incorporation of the viral envelope (Env) glycoproteins and can influence particle infectivit

24 ld-type levels of the Gag cleavage products, Env glycoproteins, and reverse transcriptase activity wh

25 c antibody responses against HIV-1 envelope (Env) glycoproteins, and little is known about how the ra

26 luble oligomeric form of an avian retroviral Env glycoprotein (API) and soluble forms of its receptor

27 The Env glycoproteins are synthesized as a polyprotein precu

28 Compact, glycan-restricted envelope (Env) glycoproteins are selected during heterosexual tran

29 The HIV-1 envelope (Env) glycoprotein binds to host cell receptors to mediat

30 ector priming followed by purified envelope (Env) glycoprotein boosting.

31 tance genes Fv4 and Rmcf in that it produces Env glycoprotein but fails to produce infectious virus;

32 ring of soluble mimetics of the trimeric HIV Env glycoprotein (commonly termed gp140 immunogens).

33 However, the mechanism by which the Env glycoprotein complex is incorporated into virus part

34 s immunized with recombinant HIV-1 envelope (Env) glycoprotein constructs.

35 osting with a recombinant trimeric envelope (Env) glycoprotein delivered in MF59 adjuvant.

36 IV-1 and simian immunodeficiency virus (SIV) Env glycoproteins, despite no HIV/SIV-related proteins b

37 biased lambda light chain use during the HIV Env glycoprotein (Env) response in HIV infection and vac

38 The V3 loop of the ENV glycoprotein exerts a dominant influence on the inte

39 se in mice that is largely mediated by viral Env glycoprotein expression within central nervous syste

40 and the filovirus Ebola use their envelope (Env) glycoproteins for this purpose.

41 xpressing clade B Gag-Pol fusion protein and Env glycoproteins from clades A, B, and C) was administe

42 brane-spanning domain (MSD) of the envelope (Env) glycoprotein from human (HIV) and simian immunodefi

43 Envelope (Env) glycoproteins from different HIV-1 isolates exhibit

44 ities of 48 donor and 25 recipient envelope (Env) glycoproteins from five subtype C heterosexual tran

45 deficiency viruses (SHIVs) bearing envelope (Env) glycoproteins from primary HIV-1 strains fail to in

46 attachment and entry properties of envelope (Env) glycoproteins from T/F and chronic control (CC) vir

47 Biologically functional clade C envelope (Env) glycoproteins from the chronically (donor) and newl

48 and highlight the ability of MA to influence Env glycoprotein function.

49 referentially bind the HIV (HIV-1) envelope (Env) glycoprotein (gp) trimer and broadly neutralize the

50 d many recognize novel epitopes on envelope (Env) glycoprotein gp120, illuminating new targets for va

51 tibodies (bNAbs) against the viral envelope (Env) glycoproteins gp120 and gp41, but no immunogen has

52 an immunodeficiency type 1 (HIV-1) envelope (Env) glycoprotein (gp120) to CD4 triggers the induction

53 0.002) in the V1 to V4 region of the surface Env glycoprotein, gp120, compared to the B cohort.

54 Because HIV-1 Env glycoprotein has been implicated in bystander apopto

55 We recently reported that an Env glycoprotein immunogen (o-gp140SF162DeltaV2) contain

56 smid-based and recombinant protein envelope (Env) glycoprotein immunogens were derived from a primary

57 activities against conserved epitopes of the env glycoprotein in cultures induced with the AV3 mutant

58 sulted in the stable secretion of a trimeric Env glycoprotein in mammalian cell cultures.

59 tail of gp41 and the matrix domain of Gag in Env glycoprotein incorporation.

60 For murine leukemia virus envelope (MLV Env) glycoprotein, incorporation into foreign viral part

61 For murine leukemia virus envelope (MLV Env) glycoprotein, incorporation into foreign viral part

62 late immune responses to the HIV-1 envelope (Env) glycoprotein induced by DNA vaccination.

63 in this domain disrupt the incorporation of Env glycoproteins into virions and markedly impair virus

64 The incorporation of viral envelope (Env) glycoproteins into nascent particles is an essentia

65 eting of Gag, the incorporation of envelope (Env) glycoproteins into nascent particles, and the nucle

66 The incorporation of envelope (Env) glycoproteins into virions is an essential step in

67 n of the human immunodeficiency virus type 1 Env glycoprotein is important for endocytosis from the p

68 The gp120 subunit of the HIV Env glycoprotein is responsible for receptor interaction

69 Although processing of the Env glycoproteins is not changed, proteasome inhibitors

70 Incorporation of the viral envelope (Env) glycoprotein is a critical requirement for the prod

71 unodeficiency virus type 1 (HIV-1) envelope (Env) glycoprotein is oligomeric, with the major points o

72 unodeficiency virus type 1 (HIV-1) envelope (Env) glycoprotein is oligomeric.

73 he high-mannose patch on the HIV-1 envelope (Env) glycoprotein is the epicenter for binding of the po

74 n immunodeficiency virus type 1 (HIV-1) gp41 Env glycoprotein, is a potent inhibitor of virus infecti

75 Wild-type Env glycoproteins lack detectable affinity for supersite

76 mation by selectively inactivating sensitive Env glycoproteins, likely through altering their conform

77 e env segments, that distinct regions of the Env glycoprotein may be important for utilization of dif

78 Consequently, the Env glycoprotein-mediated fusion function constitutes an

79 HIV-1 Env glycoprotein-mediated fusion is initiated upon seque

80 lymphotropic virus type 1 (HTLV-1) envelope (Env) glycoprotein mediates binding of the virus to its r

81 The HIV-1 envelope (Env) glycoprotein mediates viral entry during both cell-

82 has been associated with expression of viral Env glycoprotein; Northern blotting with specific hybrid

83 ane subunit (TM), the fusion subunit, of the Env glycoprotein of the subtype A avian sarcoma and leuk

84 lizable strategy for constructing SHIVs with Env glycoproteins of interest, including those that in h

85 The envelope (Env) glycoprotein of HIV is an important determinant of

86 The envelope (Env) glycoprotein of HIV is expressed on the surface of

87 The envelope (Env) glycoprotein of HIV is the only intact viral protei

88 The envelope (Env) glycoprotein of human immunodeficiency virus (HIV)

89 The envelope (env) glycoprotein of human immunodeficiency virus type 1

90 The envelope (Env) glycoprotein of human immunodeficiency virus type 1

91 Interestingly, the envelope (Env) glycoprotein of this clade B virus had a rare GPEK

92 The envelope (Env) glycoproteins of both viruses can transform rodent

93 omains of the strikingly conserved envelope (Env) glycoproteins of bovine leukemia virus (BLV) and it

94 ic Env proteins do not resemble the trimeric Env glycoprotein on HIV-1 viruses, which has implication

95 The envelope (Env) glycoproteins on these HIV-1 variants expose a core

96 The role of virus replication, Env glycoprotein phenotype, and immune activation (IA) i

97 The HIV-1 envelope (Env) glycoproteins play an essential role in the virus r

98 unodeficiency virus type 1 (HIV-1) envelope (Env) glycoprotein poses a major challenge for the develo

99 bodies (nnAbs) specific to the HIV envelope (Env) glycoproteins present at the surface of virus sensi

100 ibody (NAb) response against viral envelope (Env) glycoproteins present during acute and early infect

101 The HIV-1 Env glycoprotein presents a dense patchwork of host cell

102 on SIVMAC but expressing the HIV-1 envelope (Env) glycoproteins (SHIVs) remains the most powerful mod

103 Most neutralizing antibodies target the Env glycoprotein spikes found on the virus surface.

104 abling a more complete representation of the Env glycoprotein structure.

105 uman immunodeficiency virus type 1 envelope (Env) glycoprotein structure and function is based on stu

106 tly visualize trilobed presumptive envelope (env) glycoprotein structures on the surface of negativel

107 tance genes control expression of xenotropic env glycoprotein that interferes with exogenous virus in

108 s have identified targets on HIV-1 envelope (Env) glycoprotein that are vulnerable to antibody neutra

109 onformational changes in the viral envelope (Env) glycoprotein that lead to membrane fusion.

110 Ps) bear nonnative "junk" forms of envelope (Env) glycoprotein that may undermine the development of

111 we review our current understanding of HIV-1 Env glycoprotein trafficking and incorporation into viri

112 Much is currently known about the HIV-1 Env glycoprotein trafficking pathway and the structure o

113 ration nickel-based liposomes captured HIV-1 Env glycoprotein trimers via a noncovalent linkage with

114 a recombinant vaccinia virus expressing 89.6 Env glycoprotein (vBD3) in a mouse challenge model, we o

115 Surprisingly, the +3L Env glycoprotein was able to produce infectious particle

116 owever, the stability of the cell-associated Env glycoprotein was decreased and Env incorporation int

117 Instead, the HIV-2 Env glycoprotein was found to antagonize BST-2 in some i

118 A retroviral vector that does not encode any Env glycoprotein was packaged into retroviral particles

119 In contrast, the RSV Env glycoprotein was robustly recruited only to the homo

120 Twenty HIV-1 Env glycoproteins were examined for their ability to bin

121 Interestingly, AIP of HIV-1 Env glycoproteins were found to correlate inversely with

122 aCFI(HXB2/89.6) vector expressing a modified Env glycoprotein with C-terminal mutations intended to m

123 s dispensable for the incorporation of HIV-1 Env glycoproteins with a shortened cytoplasmic domain.

124 mmunodeficiency virus type 1 (HIV-1), encode Env glycoproteins with unusually long cytoplasmic tails,

125 ncluding HIV-1, have transmembrane envelope (Env) glycoproteins with cytoplasmic tails that are quite

126 with murine leukemia virus (MuLV) envelope (Env) glycoproteins without affecting infectivity conferr