ライフサイエンスコーパス: F1 hybrid

1 nbred lines B73 and Mo17 produce a heterotic F1 hybrid.

2 s in D. melanogaster, D. simulans, and their F1 hybrid.

3 crease in genome-wide DNA methylation in the F1 hybrid.

4 abundance of species-specific transcripts in F1 hybrids.

5 ross between C3H/HeJ(+/wan) and CAST/Ei(+/+) F1 hybrids.

6 synaptonemal complexes of annual x biennial F1 hybrids.

7 Only a subset of these would act in F1 hybrids.

8 and aggressive behaviour of their reciprocal F1 hybrids.

9 is variable in synthetic Arabidopsis suecica F1 hybrids.

10 C57BL/6 phenotype is dominant in reciprocal F1 hybrids.

11 ility of both male and female gametes in the F1 hybrids.

12 tely 3.6% within inbred strains and isogenic F1 hybrids.

13 as Marker-1' ('TM-1'), 'Pima 3-79' and their F1 hybrids.

14 us with different Prdm9 alleles and in their F1 hybrids.

15 ting immediate suppression of p-homeologs in F1 hybrids.

16 is and Nasonia giraulti and their reciprocal F1 hybrids.

17 -parental segregating populations instead of F1 hybrids.

18 ed vegetative and reproductive yields of the F1 hybrids.

19 o natural selection than if they were frozen F1 hybrids.

20 ng female rats of six inbred strains and six F1 hybrids.

21 gger for the meiotic arrest of interspecific F1 hybrids.

22 and their segregation in (C57BL/6JxC3H/HeJ) F1 hybrids.

23 sophila melanogaster, D. simulans, and their F1 hybrids.

24 have generated a uniform genetically stable F1 hybrid (129SvEv/C57BL/6) mouse line harboring the CRE

25 metamorphic-failure species) and metamorphic F1 hybrids (A. mexicanum x A. tigrinum tigrinum).

26 mbinant inbred strains (AXB/BXA), reciprocal F1 hybrids, a chromosome (Chr) 7 consomic line, and thre

27 A mixed source of parasites (containing F1 hybrids) also showed no difference in infection betwe

28 tic regulation of PIA was investigated using F1 hybrid and congenic strain analysis to determine the

29 in the C. maxima x C. moschata interspecific F1 hybrid and their two parents indicates the predominan

30 omoting leaf growth were up-regulated in the F1 hybrids and hybrid mimics, suggesting that increased

31 mpatibility, leading to increased fitness of F1 hybrids and recovery in the F2 generation.

32 homoeologous gene pairs in the allopolyploid F1 hybrids and suggest that high-parental expression-lev

33 frequency of disrupted mtDNA transmission in F1 hybrids and suggest that two separate mechanisms, one

34 7BL/6J females with 129/SvJ males to make an F1 hybrid, and crossing F1 males to F1 females to produc

35 cumulative disease frequencies in parental, F1 hybrid, and F2 mice, derived from the EAE-susceptible

36 re we show, by using inbred strains of mice, F1 hybrids, and segregating populations, that, unlike Bp

37 an interspecies (M.musculus x M.m.castaneus) F1 hybrid animal, expression of Ipw is limited to the pa

38 mimics, in which the characteristics of the F1 hybrid are stabilized.

39 introgression is relatively common, whereas F1 hybrids are correspondingly scarce.

40 F1 hybrids are viable but sterile: the gametes they prod

41 s of Brassica napus parental lines and their F1 hybrids at three stages of early flower development.

42 In this study, autoimmune female NZB x NZW F1 hybrid (B/W) mice were tested in shock-motivated disc

43 l-described C57Bl/6 (B6)-->(C57Bl/6 x DBA/2) F1 hybrid (B6D2F1) murine model of acute allogeneic graf

44 ression was also monitored in the reciprocal F1 hybrids B73xMo17 and Mo17xB73.

45 Tumors arising in an (I/LnJ x PyMT) F1 hybrid background appeared earlier than in the FVB/N-

46 o determine whether Fmr1 knockout mice on an F1 hybrid background are normal in their response to foo

47 ve phenotype; however, deficient mice on the F1 hybrid background were resistant to cold.

48 igh frequency on C57BL/6 X FVB and C3H x FVB F1 hybrid backgrounds.

49 RIXs are generated by producing F1 hybrids between all or a subset of parental RI lines.

50 F1 hybrids between C57BL/6 and FVB/N strains ((B6FVB)F1)

51 F1 hybrids between each of these inbred strains and the

52 w report that MR is relatively suppressed in F1 hybrids between inbred strains C57BL/6 and 129S2.

53 D. sechellia's resistance is dominant in F1 hybrids between it and its sister species D. simulans

54 F1 hybrids between resistant and susceptible congenic st

55 male sterility and segregation distortion in F1 hybrids between the Bogota and U.S. subspecies of Dro

56 rvivors of matings between female reciprocal F1 hybrids (between the DDK and C57BL/6J inbred mouse st

57 be potentially useful for first-generation (F1) hybrid breeding.

58 parental species result in poor fertility of F1 hybrids, but through recombination, novel homozygous

59 To define its contribution, (NZB x NZW)F1 hybrids (BWF1) containing two, one, or no copies of t

60 vey of T-cytoplasm maize lines, inbreds, and F1 hybrids by mitochondrial RNA gel blot analyses reveal

61 (BALB/cByJ, DBA/2J, C57BL/6J, and SJL/J), an F1 hybrid (C57 x SJL), and 1 outbred strain (CD1) were t

62 the associated changes in sRNA levels in the F1 hybrid can be maintained in subsequent generations an

63 F1 hybrids can outperform their parents in yield and veg

64 Heterosis is the superior performance of F1 hybrids compared with their homozygous, genetically d

65 tissue-specific increase of active genes in F1-hybrids compared with their inbred parents.

66 Centromeres are also stable in multiple F1 hybrid contexts.

67 y 105 Bos taurus indicus x Bos taurus taurus F1 hybrid control and LOS fetuses using RNAseq.

68 nts at an intensely active mouse hot spot in F1 hybrids derived from inbred mouse strains.

69 lls by natural killer cells of mice that are F1 hybrids derived from two inbred parental strains.

70 (B6.NZMc1[Sle1] x NZW)F1 hybrids develop severe humoral autoimmunity and fatal

71 genes with aberrant transcript abundance in F1 hybrids (either over- or underexpressed compared to b

72 r in mouse embryonic stem cells derived from F1 hybrid embryos.

73 ic mice died before 5 mo, almost half of the F1 hybrid eNOS(-/-) and eNOS(+/-) diabetic mice lived un

74 terosis refers to the phenomenon in which an F1 hybrid exhibits enhanced growth or agronomic performa

75 In C57BL/6J (B6) and (BALB x B6) F1 hybrid (F1) mice, repopulating abilities increase wit

76 Backcrossing F1 hybrid females between these two species to parental

77 Oocytes of F1 hybrid females showed the same kind of synaptic probl

78 igestion method, the resulting AR/tfm, Nu/nu F1 hybrid females were identified and back-crossed to ho

79 s offset by low genetic isolation, and lower F1 hybrid fertility increased the evolutionary independe

80 F2 progeny derived from self-pollination of F1 hybrids from four crosses (B73 x OH43, Mo17 x A632, A

81 ined Allele Specific Expression (ASE) in six F1 hybrids from Saccharomyces cerevisiae derived from cr

82 BA/2J (D2) Fog2-/+ XY(AKR) mice and (B6 x D2)F1 hybrid Gata4(ki)/+ XY(AKR) mice develop testes.

83 e selected heterozygotes can be recreated as F1 hybrids, greatly increasing the number of hybrids tha

84 These hybrid mimic lines, like the F1 hybrid, have larger leaves than the parent plant, and

85 fish, and parasite size was intermediate in F1 hybrid hosts.

86 criptome analysis of a number of Arabidopsis F1 hybrids identified changes to defense and stress resp

87 hylation and a lower expression level in the F1 hybrid, implying that the non-additively expressed si

88 F1 hybrids in Arabidopsis and crop species are uniform a

89 minance; and 3) increasing the proportion of F1 hybrids in the population could significantly increas

90 suppression of mitotic recombination in some F1 hybrids in which meiotic recombination persists indic

91 earlier germination as did the seeds of the F1 hybrids, indicating cosegregation of the genes for ro

92 scendants of a single nonrecombining asexual F1 hybrid individual.

93 we analyzed Mecp2(+/-) mice of two different F1 hybrid isogenic backgrounds and at young and old ages

94 The reciprocal F1 hybrid lines did not display parental effects on gene

95 Experiments were conducted with three F1 hybrids made using three inbred strains of mice (DBA/

96 F1 hybrid males, heterozygous at all polymorphic autosom

97 ed in D. melanogaster, to cause lethality in F1 hybrid males.

98 Analysis of backcrossed progeny of the F1 hybrids mated to Sxv mice indicates that resistance i

99 verged chromosomes to form crossovers during F1 hybrid meiosis.

100 AS F1 hybrid mice (C57BL/6J x 129) showed milder behavioral

101 ancer induction in two strains of reciprocal F1 hybrid mice CB6F1 males with high susceptibility to U

102 We used F1 hybrid mice derived from A/J and C57BL/6 matings to i

103 In contrast, infected SJL and B6xSJL F1 hybrid mice exhibit essentially complete hippocampal

104 ted the outcome of hybrid resistance whereby F1 hybrid mice reject parental BMCs.

105 However, C57BL/6J and B6C3 F1 hybrid mice responded with a greater number of infilt

106 scriptome analysis of Kras(G12D) tumors from F1 hybrid mice revealed features specific to tumor sampl

107 e frequency of MR in fibroblasts is lower in F1 hybrid mice than in either of the two parental strain

108 und the functional activity of CREB in these F1 hybrid mice to be dramatically reduced compared with

109 ptor is responsible for the ability of H2b/d F1 hybrid mice to reject H2d/d parental BMC (hybrid resi

110 Post-natal day 10 129T2xC57Bl/6 F1 hybrid mice were subjected to 0, 45, 60 or 75 min of

111 C57BL/6JxCast/EiJ F1 hybrid mice were weaned onto (1) a standard natural i

112 , X chromosome inactivation can be skewed in F1 hybrid mice, as determined by alleles at the X chromo

113 F1 hybrid mice, as well as parental A/J and C57BL/6 mice

114 he intertrial interval (ITI) using C57 x SJL F1 hybrid mice.

115 6J, C3H/HeJ, and (C57BL/6J x C3H/HeJ) (B6C3) F1 hybrid mice.

116 in the epidermis of K5Hras-transgenic (B6FVB)F1 hybrid mice.

117 lopment of invasive tumors, as are RT2 C3HB6(F1) hybrid mice.

118 or T cells in a well-established parent-into-F1 hybrid model (C57BL/6J-->C3FeB6F1/J).

119 F1 hybrid mouse embryos were subjected to three experime

120 basis of heterosis, here we used a subset of F1 hybrids, named a partial North Carolina II design, to

121 ins of mice, such as A/J and (C57BL/6J x A/J)F1 hybrids, neonatal thymectomy-induced autoimmune ovari

122 on of polymorphisms in 129 F2 progeny of one F1 hybrid obtained by crossing two genetically divergent

123 uences for heterozygous samples including an F1 hybrid of Arabidopsis thaliana, the widely cultivated

124 An F1 hybrid of F344 and BN exhibited significant pituitary

125 ly germline-competent ES cell lines from the F1 hybrid of NOD and 129 for use in NOD gene targeting.

126 y admixed individuals, but sour orange is an F1 hybrid of pure C. maxima and C. reticulata parents, t

127 F1 hybrids of A x B have intermediate floral characters

128 F1 hybrids of both sexes mate frequently with both pure

129 m all of the other commonly used strains and F1 hybrids of C57BL/6 and BALB/c mice.

130 NA pathway function and TE regulation in the F1 hybrids of interspecific crosses between D. melanogas

131 Unlike other F1 hybrids of M. castaneus, these F1 mice were resistant

132 The F1 hybrids of New Zealand Black (NZB) and New Zealand Wh

133 F1 hybrids of New Zealand Black (NZB) and New Zealand Wh

134 F1 hybrids of New Zealand black (NZB) and New Zealand wh

135 to the development of autoimmune disease in F1 hybrids of New Zealand black (NZB) and white (NZW) mi

136 2 and CYP6A8 RNA levels were measured in the F1 hybrids of overproducer (91-R and MHIII-D23) and unde

137 In a separate experiment, F1 hybrids of SHRxBN strains and parental BN and SHR und

138 evelopment or progression of HIVAN by making F1 hybrids of TgFVB with five other inbred strains (CBA,

139 F1 hybrid offspring from 2 major PIA-susceptible strains

140 Analysis of (BALB/c x C57BL/6) F1 hybrid offspring indicates that PIR molecules bearing

141 tially methylated between the two alleles in F1 hybrid offspring, recapitulating the parental methyla

142 First filial (F1) hybrid offspring, which were gestated by B6 or cJ da

143 erential chromosome pairing at meiosis in an F1 hybrid population, which indicates the importance of

144 their five matched controls and a set of 10 F1 hybrid populations derived from reciprocal crosses be

145 was also performed on similar tissues of the F1 hybrids produced by crossing B73 and each of the thre

146 bred lines B73 and Mo17 and their reciprocal F1 hybrid progeny in primary roots under control and wat

147 he maize inbred lines B73 and Mo17 and their F1 hybrid progeny is reflected in differential, nonaddit

148 tion is now complete because of sterility of F1 hybrid progeny, prezygotic isolation is still incipie

149 four different primary root tissues of their F1-hybrid progeny.

150 The Brown Norway/Fischer 344 F1 hybrid rats (F344BNF1) is a newer rat model and is em

151 uscle fibers from Fischer 344 x Brown Norway F1 hybrid rats of ages 5, 18, and 38 months through 1000

152 scle of 34-month-old Fisher 344/Brown Norway F1 hybrid rats, a well accepted animal model for biologi

153 aged (>22 months) Fisher 344 x Brown Norway F1 hybrid rats, compared to young (4-6 month) and middle

154 by PhIP in Sprague-Dawley (SD)xWistar Furth F1 hybrid rats.

155 nd aged (30 months) Fischer 344/Brown Norway F1 hybrid rats.

156 diac transplants between parental donors and F1 hybrid recipients to provide evidence that NK cells,

157 ponse genes are significantly altered in the F1 hybrids relative to the parental lines.

158 The F1 hybrids resembled one parent or the other, without sh

159 e of inbred allelic expression levels in the F1 hybrid, resulting in additive expression patterns.

160 s of two isogenic lines and their reciprocal F1 hybrids revealed 5820 genes as significantly differen

161 In flowering plants, F1 hybrid seed lethality is a common outcome of crosses

162 We found that F1 hybrid seed lethality is an exceptionally strong isol

163 Male sterility plays an important role in F1 hybrid seed production.

164 Phenotypically, the F1 hybrids show remarkable heterosis in silique number a

165 ession assays of Bmp6 in developing teeth in F1 hybrids show that cis-regulatory changes have elevate

166 The F1 hybrids showed an average percentage of intima interm

167 the changes in gene expression level in the F1 hybrids showed that the majority of the small interfe

168 F1 hybrid sterility and "hybrid breakdown" of F2 and lat

169 y represent a universal mechanistic basis of F1 hybrid sterility manifested by pachytene arrest.

170 ent species' genomes is not a major cause of F1 hybrid sterility, although it may contribute to repro

171 The 100% cis-regulation in F1 hybrids suggests the methylation machinery is conserv

172 DNase I for chromatin fragmentation to mouse F1 hybrid systems.

173 lusters had a higher expression level in the F1 hybrids than in the parents, and that there was an in

174 aspecific Arabidopsis (Arabidopsis thaliana) F1 hybrids that show different levels of heterosis at ma

175 on on survival or reproductive characters in F1-hybrids, these results suggest that introgression sho

176 th either C57BL/6J or DBA/2J wild-type mice, F1 hybrid Tmc1Bth/+ progeny have increased hearing loss

177 mined allele-specific expression (ASE) in an F1 hybrid to study how alleles from two Arabidopsis thal

178 2 mice from a backcross of (C57BL/6JxDBA/2J) F1 hybrids to DBA/2J mice confirmed this linkage (LOD>50

179 a backcross of (B6.CAST-Cdh23 Ahl+ xDBA/2J) F1 hybrids to DBA/2J mice demonstrated a genetic interac

180 ila with a range of divergence times and use F1 hybrids to examine inheritance patterns and disentang

181 tion, we delete the core PRC2 protein EED in F1 hybrid trophoblast stem cells (TSCs), which undergo i

182 Surprisingly, the F1 hybrid tumors were not hemorrhagic and had hemoglobin

183 ly and were maintained when the fertility of F1 hybrids was high.

184 Lastly, by comparing reciprocal F1 hybrids, we identified evidence of imprinting in the

185 allele-specific transcript abundance in the F1 hybrids, we were able to measure the abundance of cis

186 To follow segregation of hearing loss, F1 hybrids were backcrossed to the parental strains with

187 al amounts of CYP6A2 and CYP6A8 mRNAs in the F1 hybrids were lower than half the amounts of these RNA

188 Cardiac allografts from Lewis x Brown Norway F1 hybrids were rejected in 7+/-1 days in Lewis rats.

189 ed strains, wild species and subspecies, and F1 hybrids were studied using an unbiased electron micro

190 Since both male and female F1 hybrids were used to produce backcross progeny, these

191 n the Arabidopsis C24/Landsberg erecta (Ler) F1 hybrids, which show patterns of inheritance dependent

192 of the differentially expressed genes in the F1 hybrid with those of eight hybrid mimic lines identif

193 ssecting cis and trans effects is to compare F1 hybrids with F0 homozygotes.

194 tty/Spontaneously hypertensive heart failure F1 hybrid (ZSF1) rats.