ライフサイエンスコーパス: FDP

1 FDP + CsA prolongs cardiac survival and FDP inhibits T-c

2 FDP completely inhibited interleukin-2 expression at 5,0

3 FDP did not stimulate transcription inhibition by CcpA n

4 FDP induction of PAI-1 suggests a matrix-cell feedback p

5 FDP maximally inhibits T-cell proliferation and concomit

6 FDPs are more potent than fibrinogen, inducing a concent

7 FDPs contain a dinuclear iron active site similar to tha

8 FDPs contain a distinctive non-heme diiron/flavin mononu

9 FDPs serve as the terminal components for reductive scav

10 s with enantiomerically pure [1-(2)H(1)](1R)-FDP revealed that the putative bisabolyl-derived 1,6-pat

11 Levels of PTF1+2, FDP, and D-dimer decreased as symptoms improved.

12 nt species from a wide phylogenetic range (3 FDPs in tropics, 5 in subtropics and 5 in temperate zone

13 4, FDP 350 mg/kg perioperatively 13.5+/-1.4, FDP 350 mg/kg twice daily 11.4+/-0.75, CsA 2.5 mg/kg dai

14 n survival in days were: saline 7.12+/-0.64, FDP 350 mg/kg perioperatively 13.5+/-1.4, FDP 350 mg/kg

15 on incubation of MtTPS5 with natural (2E,6E)-FDP.

16 to study the promiscuity of MtTPS5, (2Z,6E)-FDP, an analogue of presumptive reaction intermediates f

17 from incubations of DCS with 6F-FPP, (2Z,6E)-FDP, neryl diphosphate, 6,7-dihydro-FDP, and NDP seem to

18 rticular, the strong inhibition of DCS by 6F-FDP, coupled to the exclusive bisabolyl- and terpinyl-de

19 nit were as follows: SAP, 2.177; SWAP, 1.96; FDP, 1.277; and GRP, 1.04.

20 Fermented dairy product A (FDP-A), but neither the supernatant from FDP-A nor beta-

21 gly, the binding of the allosteric activator FDP does not directly influence the binding of the subst

22 -like and flavodoxin domains typical for all FDPs, an extra NAD(P)H:flavin oxidoreductase module and

23 As an FDP synthase, PcIDS1 could be associated with the format

24 HR: 1.61; HSP70 >0.625 ng/ml, HR; 2.26; and FDP >/=1.0 mug/ml, HR: 1.62 (p < 0.0001 for all).

25 DIC diagnostic test panel, with D-dimer and FDP providing a rapid and specific diagnosis, antithromb

26 The D-dimer and FDP tests offered the best test panel in the diagnosis o

27 ive PAI-1 is demonstrated in fibrinogen- and FDP-stimulated conditioned media.

28 These results indicate that, in Hr(NO) and FDP(NO), the coordinated NO is exceptionally electron ri

29 allosteric communication between the PEP and FDP sites in an allosteric relay mechanism.

30 Thus, communication between the PEP and FDP sites occurs structurally through the metal by an al

31 that simultaneous binding of Mn2+, PEP, and FDP is considerably favored over the sum of their indepe

32 g insight to the severity and prognosis, and FDP (rapid and less expensive than D-dimer) to follow-up

33 tivity 100%, and specificity 67%; PT/PTT and FDP combination (n = 71), efficiency 86%, sensitivity 91

34 videnced by reduced contrast sensitivity and FDP performance, accompanied by alterations in inner and

35 FDP + CsA prolongs cardiac survival and FDP inhibits T-cell proliferation.

36 This is followed by FDP (n = 71), efficiency 87%, sensitivity 100%, and spec

37 Incubation of [(14)C]FDP with recombinant human squalene synthase led to [(14

38 ereas it yields only 18% C10 GDP but 82% C15 FDP in the presence of Mg(2+).

39 binations, CcpA/NADP/HPr-P (Ser-46) and CcpA/FDP/HPr-P (Ser-46) synergistically stimulated DNA-bindin

40 Conversely, FDP-A prevented a decrease in Ruminococcus and increased

41 ggregate score based on serum levels of CRP, FDP, and HSP70 is a predictor of future risk of death an

42 Serum levels of CRP, FDP, and HSP70 were measured in 3,415 consecutive patien

43 Cyanobacterial FDPs constitute a specific protein group that evolved to

44 Evolution of unique cyanobacterial FDPs is discussed as a prerequisite for the development

45 ere as follows: SAP, 4.85 dB; SWAP, 9.03 dB; FDP, 4.29 dB; and GRP, 1.36 dB.

46 ative mechanisms, we examined a deflavinated FDP (deflavo-FDP) from Thermotoga maritima.

47 Both deflavo-FDP(NO) and the mononitrosyl adduct of the flavinated FP

48 stable diiron-mononitrosyl complex (deflavo-FDP(NO)) that can react further with NO to form N(2)O.

49 ric oxide up to one NO per diferrous deflavo-FDP results in formation of a diiron-mononitrosyl comple

50 Reactions of the reduced (diferrous) deflavo-FDP with nitric oxide were examined by UV-vis absorption

51 sms, we examined a deflavinated FDP (deflavo-FDP) from Thermotoga maritima.

52 n addition of NO to the mononitrosyl deflavo-FDP supports the hyponitrite mechanism, but the concomit

53 ble diiron-dinitrosyl complex in the deflavo-FDP is consistent with a super-reduction pathway in the

54 The deflavo-FDP retains an intact diiron site but does not exhibit m

55 Both NO-treated and as-isolated deflavo-FDPs regain full NOR and O(2)R activities upon simple ad

56 ulted in N-(3-formyl-3,4-dehydropiperidino) (FDP)-lysine adducts at positions 5 and 25 and led to a c

57 Recently, we showed that FMN-free diferrous FDP from Thermotoga maritima exposed to 1 equiv NO forms

58 (2Z,6E)-FDP, neryl diphosphate, 6,7-dihydro-FDP, and NDP seem to be in better agreement with the pot

59 We propose the use of D-dimer, FDP, and antithrombin as the DIC diagnostic test panel,

60 l sulfoxide (DMSO)-fructose 1,6-diphosphate (FDP) i.p. for seven days and retested on the water maze.

61 Fructose-1,6-diphosphate (FDP) reduces postischemic reperfusion injury and is used

62 imulated 2-fold by fructose-1,6-diphosphate (FDP), 1.5-fold by oxidized or reduced forms of NADP, and

63 osteric activator, fructose 1,6-diphosphate (FDP), does not directly communicate with the substrate,

64 metabolism [e.g., fructose 1,6-diphosphate (FDP), phosphoenolpyruvate (PEP), and citrate] and by the

65 E,E)-farnesyl and dimethylallyl diphosphate (FDP and DMADP) to generate the semiochemicals (E)-beta-f

66 (GGDPS) that condenses farnesyl diphosphate (FDP) and isopentenyl pyrophosphate.

67 (GDP) and only 4% C15-farnesyl diphosphate (FDP) in the presence of Co(2+) or Mn(2+) as a cofactor,

68 potency at inhibiting farnesyl diphosphate (FDP) synthase (their intracellular target), the N-BPs ar

69 t cyclization of (E,E)-farnesyl diphosphate (FDP) to the cadinane sesquiterpene delta-cadinene, the p

70 yzes the conversion of farnesyl diphosphate (FDP) to the plant sesquiterpene (+)-germacrene A.

71 olyisoprenyl phosphate farnesyl diphosphate (FDP), PSDP was not a substrate for type 2 lipid phosphat

72 oprenoid intermediate, farnesyl diphosphate (FDP), to sesquiterpene phytoalexins in cotton (Gossypium

73 ural substrate (2E,6E)-farnesyl diphosphate (FDP).

74 rom the reaction of fluorescein diphosphate (FDP) and immuno-complex conjugated with ALP.

75 f concentrations of fluorescein diphosphate (FDP), a fluorogenic alkaline phosphatase substrate, with

76 DMSO-FDP treatment was discontinued and rats were retested on

77 The results indicate that a DMSO-FDP combination improves VSM secondary to chronic brain

78 After DMSO-FDP, a 54% improvement in their VSM was seen which nearl

79 ssypium arboreum cyclizes (1RS)-[1-2H](E, E)-FDP to >98% [5-2H]and [11-2H]CDN.

80 proposed for the formation of CDN from (E,E)-FDP and for the formation of CDN, (E)-beta-farnesene, an

81 ues demonstrate that the synthase uses (E,E)-FDP as effectively as (3R)-nerolidyl diphosphate in the

82 ults on the same deflavinated and flavinated FDP, which detected N2O as a product.

83 ng, among others, deuterated and fluorinated FDPs.

84 er training, either for natural teeth or for FDP (all P >0.05).

85 MRI acquisition time for FDP was 17 minutes, versus 3 minutes for the AP.

86 There are four FDPs in Synechocystis sp. PCC 6803 (Flv1 to Flv4).

87 e mononitrosyl adduct of the flavinated FPD (FDP(NO)) show nu(NO) at 1681 cm(-1), which is also unusu

88 Different from FDP homodimers in anaerobic microbes, Synechocystis Flv2

89 A (FDP-A), but neither the supernatant from FDP-A nor beta-irradiated (IR) FDP-A, caused a significa

90 n oxidoreductase module and thus differ from FDPs in other Bacteria and Archaea.

91 ination generally depend on scales in global FDPs.

92 ivity with a substrate preference for PSDP > FDP > phosphatidic acid.

93 rium-labeling experiments with [12,13-(2)H6]-FDP support a germacrene-humulene rearrangement linking

94 his bioactivity of FDP is conserved in human FDP, is not limited to trophoblast cells, and is associa

95 results demonstrate that viable bacteria in FDP-A reduced CR-induced colonic crypt hyperplasia and p

96 tion of Jak2 and Stat5a and Stat5b occurs in FDP-C1 cells expressing either the entire GH receptor or

97 ron-mononitrosyl complex with NO, whereas in FDP(NO) the increased nucleophilicity of the nitrosyl gr

98 t of an unusually small FeNO angle, while in FDP(NO), the Fe(III)(NO(-)) structure may be due to a se

99 cterization of diiron redox intermediates in FDPs.

100 lation exists between potency for inhibiting FDP synthase and potency for inhibiting Dictyostelium di

101 d that, although high potency for inhibiting FDP synthase is favored when the nitrogen atom in a N-BP

102 ernatant from FDP-A nor beta-irradiated (IR) FDP-A, caused a significant reduction in colonic crypt h

103 rofiling the gut microbiota revealed that IR-FDP-A promoted higher levels of phylotypes belonging to

104 5.0 mg/kg daily 12.4+/-0.81, CsA 2.5 mg/kg + FDP 350 mg/kg twice daily 17.6+/-0.4, and CsA 5 mg/kg +

105 kg twice daily 17.6+/-0.4, and CsA 5 mg/kg + FDP 350 mg/kg twice daily 28.2+/-0.97.

106 We conclude that the macaque FDP consists of four neuromuscular compartments, each of

107 From baseline to month 24, mean FDP foveal sensitivity decreased in the placebo group (-

108 A higher mean FDP foveal sensitivity in the doxycycline group compared

109 ling free energies deltaG(Mn-PEP), deltaG(Mn-FDP), and deltaG(PEP-FDP) are -3.88, -1.09, and -0.22 kc

110 Here, we document that this bioactivity of FDP is conserved in human FDP, is not limited to trophob

111 studied the mechanism for the cyclization of FDP and the putative intermediate, nerolidyl diphosphate

112 ulene, which arises from 1,11-cyclization of FDP.

113 respond maximally, influenced the impact of FDP on perception, functional topography, and connectivi

114 In this study, the influence of FDP on the interactions of PEP and Mn2+ and the influenc

115 n of Mn2+ to YPK enhances the interaction of FDP by -1.6 kcal/mol and the interaction of PEP by -2.8

116 luence of PEP and Mn2+ on the interaction of FDP with YPK were measured, where possible, by direct bi

117 ant difference was observed in the levels of FDP, D-dimer, and MPV among the three groups of the pati

118 A significant reduction of FDP mean deviation (MD) was exhibited in PRP-treated pat

119 ion of the diferric and diferrous species of FDP.

120 ate indicated that the diferric structure of FDP prior to and immediately after turnover with NO are

121 n intermediate in the NOR catalytic cycle of FDPs.

122 hree-dimensional structures, particularly of FDPs with a clear preference toward either O2 or NO, two

123 iderably fewer plaque deposits were found on FDP (43%).

124 However, only FDP competently turns over NO to N2O.

125 T restored with fiber post and either SCs or FDPs was 69.2%.

126 te kinetic data for the interactions of PEP, FDP, and Mn2+ with yeast pyruvate kinase (YPK), we have

127 ct binding data for the interactions of PEP, FDP, and Mn2+ with YPK.

128 mol relative to the analogous YPK-Mn(2+)-PEP-FDP complex.

129 ltaG(Mn-PEP), deltaG(Mn-FDP), and deltaG(PEP-FDP) are -3.88, -1.09, and -0.22 kcal/mol, respectively.

130 and coupling free energy term, deltaG(Mn-PEP-FDP), indicates that simultaneous binding of Mn2+, PEP,

131 t sensitivity, frequency doubling perimetry (FDP), Humphrey visual fields, photostress recovery, and

132 ional factors (frequency doubling perimetry [FDP], Humphrey photopic Swedish Interactive Thresholding

133 Frequency-dependent plasticity (FDP) describes adaptation at the synapse in response to

134 77)Lu, the fractional decrease in platelets (FDP) correlates well with both the radioactive dose admi

135 ue data sets from the forest dynamics plots (FDP) network, which shed light on the factors responsibl

136 ast region perform in forest dynamics plots (FDPs) from global CTFS-ForestGEO network, we analyzed DN

137 omodulin, fibrinolytic degradation products (FDP) of fibrin induce apoptotic cell death of a speciali

138 TT), fibrinogen/fibrin degradation products (FDP), and fibrinogen were used most frequently as DIC di

139 protein (CRP), fibrin degradation products (FDP), and heat shock protein 70 (HSP70) levels-would be

140 tective effects of fermented dairy products (FDPs) in an infection model, using the mouse pathogen Ci

141 Fibrin degradation products (FDPs) and interleukins 6 and 10 (IL-6 and IL-10) were un

142 ibrin generates fibrin degradation products (FDPs) with multiple biological activities in several cel

143 The macaque flexor digitorum profundus (FDP) consists of a muscle belly with four neuromuscular

144 ls in patients with fixed dental prostheses (FDP), and effectiveness of computer-based training (CBT)

145 2) 3- to 4-unit PFM fixed dental prostheses (FDPs), with 1 healthy and 1 endodontically treated and f

146 Flavo-diiron proteins (FDPs) are non-heme iron containing enzymes that are wide

147 unique active site of flavo-diiron proteins (FDPs) consists of a nonheme diiron-carboxylate site prox

148 Flavodiiron proteins (FDPs) are a family of enzymes endowed with bona fide oxy

149 Flavodiiron proteins (FDPs) catalyze reductive scavenging of dioxygen and nitr

150 Flavodiiron proteins (FDPs) play important roles in the microbial nitrosative

151 The role of flavodiiron proteins (FDPs), originally called A-type flavoproteins or Flvs, i

152 Cyanobacterial flavodiiron proteins (FDPs; A-type flavoprotein, Flv) comprise, besides the be

153 as four genes encoding flavodiiron proteins (FDPs; Flv1 to Flv4).

154 er was the regular full diagnostic protocol (FDP) analyzed.

155 PAI-1 mRNA, protein, and activity by soluble FDPs and fibrinogen in rat lung fibroblast monolayers.

156 lly sighted trained observers for SAP, SWAP, FDP, and GRP.

157 We show that FDP extends to the cortical level and is influenced by c

158 Furthermore, study results suggest that FDP, which primarily measures inner retinal function, is

159 The FDP and D-dimer combination (n = 39) had the highest dia

160 studies revealed that HN is preferred at the FDP site, that HG is preferred at the GGDP site, and tha

161 90)Y, there was poor correlation between the FDP and the radioactive dose administered (r = 0.20) or

162 ostic accuracy was equivalent to that of the FDP and resulted in an additional cancer yield of 18.2 p

163 terpretation of the complete AP, as with the FDP, allowed diagnosis of all cancers (11 [100%] of 11).

164 tis sp. PCC 6803 has four genes encoding the FDPs.

165 Unlike higher plants that lack the FDPs and use the Proton Gradient Regulation 5 to safegua

166 thholding FDP was found to be noninferior to FDP for the study population as a whole (95% CI for adju

167 Withholding FDP was noninferior to FDP in holes </=400 mum in diameter.

168 positive predictive value (PPV) of AP versus FDP were equivalent (94.3% v 93.9% and 24.4% v 23.4%, re

169 Treatment of mice with FDP formulas A, B, and C or a control product did not af

170 Ninety-three patients with FDP were randomly allocated to one of three training gro

171 aque removal skills are low in patients with FDP.

172 Withholding FDP was noninferior to FDP in holes </=400 mum in diamet

173 Although withholding FDP was found to be noninferior to FDP for the study pop

174 m in diameter, noninferiority of withholding FDP could not be concluded.

175 mine the extent to which compartments within FDP act on single versus multiple digits, we stimulated