ライフサイエンスコーパス: FLICE-inhibitory protein

1 l molecule c-FLIP (cellular homolog of viral FLICE inhibitory protein).

2 ellular inhibitor of apoptosis protein-2 and FLICE inhibitory protein.

3 were attenuated by the forced expression of FLICE-inhibitory protein.

4 , inhibitor of apoptosis proteins, and viral FLICE-inhibitory proteins.

5 lly downregulates expression of the cellular FLICE inhibitory protein, a negative regulator of death

6 002 decreases expression of c-FLIP (cellular FLICE inhibitory protein), an inhibitor of caspase-8 act

7 pression of the antiapoptotic genes cellular FLICE-inhibitory protein and Bcl-2.

8 rotein that is homologous to cellular FLIPs (FLICE-inhibitory proteins) and is proposed to inhibit Fa

9 riety of anti-apoptotic molecules, including FLICE inhibitory protein, Bcl-2, and Mcl-1, which protec

10 ntly attenuated, but the expression level of FLICE inhibitory protein c-FLIP(L), which had been shown

11 FLICE inhibitory protein (c-FLIP) is an important regula

12 The Fas apoptosis inhibitor molecule and FLICE inhibitory protein (c-FLIP) proteins are up-regula

13 d T cells led to down-regulation of cellular FLICE inhibitory protein (c-FLIP), an inhibitor of apopt

14 Fas-ligand interleukin-1-converting enzyme (FLICE)-inhibitory protein (c-FLIP), an endogenous antago

15 Cellular FLICE-inhibitory protein (c-FLIP(L)) is a key regulator

16 receptor, and reduces the levels of cellular FLICE-inhibitory protein (c-FLIP) (both the long and sho

17 ib down-regulated the expression of cellular FLICE-inhibitory protein (c-FLIP), a major negative regu

18 oxib action based on degradation of cellular FLICE-inhibitory protein (c-FLIP), a major regulator of

19 Cellular FLICE-inhibitory protein (c-FLIP), an antioxidant and an

20 MRIT, also known as c-FLICE-inhibitory protein (c-FLIP), is an enzymatically i

21 uced the mRNA and protein levels of cellular FLICE-inhibitory protein (c-FLIP).

22 s was associated with a decrease in cellular FLICE-inhibitory protein (c-FLIP).

23 companied by the down-regulation of cellular FLICE-inhibitory protein (c-FLIP, I-FLICE) without evide

24 aminin, but not collagen, expressed cellular FLICE inhibitory protein (cFLIP) and TNFalpha stimulatio

25 ated death domain (FADD) protein or cellular FLICE inhibitory protein (cFLIP), other proteins associa

26 oarray uncovered down-regulation of cellular FLICE inhibitory protein (cFLIP).

27 ssion of the antiapoptotic molecule cellular FLICE inhibitory protein (cFLIP).

28 ible or permanent) with deletion of cellular FLICE-inhibitory protein (cFlip) or caspase-8 in the int

29 coy receptors and the antiapoptotic cellular FLICE-inhibitory protein (cFLIP) was inconsistent across

30 ell leukemia-1 (Mcl-1) and caspase 8 homolog FLICE-inhibitory protein (cFLIP), and induced G2M cell-c

31 ll death and caspase activation by promoting FLICE-inhibitory protein degradation and mitochondrial r

32 Significantly, the viral flice inhibitory protein E8 protects from p75(NTR)-induc

33 short isoform of the caspase-8 inhibitor, c-FLICE inhibitory protein (FLIP(S)), and that FLIP(S) exp

34 ersely related to the intracellular level of FLICE inhibitory protein (FLIP) but not that of death re

35 P, an inhibitor of apoptosis, and disrupting FLICE inhibitory protein (FLIP) expression through the A

36 n of NO and concomitant decrease in cellular FLICE inhibitory protein (FLIP) expression without signi

37 ine, was associated with increased levels of FLICE inhibitory protein (FLIP), and was overcome by cyc

38 ncoding the inhibitor of caspase activation, FLICE inhibitory protein (FLIP), appears to be a direct

39 cies (ROS) generation and down-regulation of FLICE inhibitory protein (FLIP); however, the relationsh

40 D)-like interleukin-1beta-converting enzyme (FLICE) inhibitory protein (FLIP), leading to apoptosis.

41 rleukin 1 beta (IL-1beta)-converting enzyme (FLICE)-inhibitory protein (FLIP) has been reported to in

42 ysis showed higher transcript levels for the FLICE-inhibitory protein (FLIP(L)) in resistant cells an

43 ates the degradation of the long form of the FLICE-inhibitory protein (FLIP(L)), an inhibitor of deat

44 FLICE-inhibitory protein (FLIP) blocks death receptor-me

45 Levels of DcR1 and DcR2 or levels of the FLICE-inhibitory protein (FLIP) did not correlate with T

46 The caspase-8 homologue FLICE-inhibitory protein (FLIP) functions as a caspase-8

47 FLICE-inhibitory protein (FLIP) is a homolog of caspase-

48 FLICE-inhibitory protein (FLIP), an inhibitor of Fas act

49 ndent and correlated with down-regulation of FLICE-inhibitory protein (FLIP), an intracellular caspas

50 for various apoptosis inhibitors, including FLICE-inhibitory protein (FLIP), and lower procaspase-8

51 decoy recepter 2) or antiapoptotic proteins (FLICE-inhibitory protein (FLIP), inhibitor of apoptosis

52 proliferation when the caspase 8 inhibitor, FLICE-inhibitory protein (FLIP), is active.

53 Expression of one such inhibitor, FLICE-inhibitory protein (FLIP), was highest in the TRAI

54 ibited expression of the caspase-8 inhibitor FLICE-inhibitory protein (FLIP), which functions downstr

55 ity correlated with a progressive decline in Flice-inhibitory protein (FLIP), which was induced withi

56 Mature lymphocytes express FLICE inhibitory proteins (FLIPs) that block death recep

57 FLICE-inhibitory proteins (FLIPs) are a family of viral

58 apoptotic effectors such as Bcl-2, p53, and FLICE inhibitory protein in cancer cell anoikis is also

59 sociated herpesvirus (KSHV) K13/vFLIP (viral Flice-inhibitory protein) induces transcription of numer

60 c-FLIP (cellular FLICE inhibitory protein) is an enzymatically inactive r

61 -associated herpesvirus (KSHV)-encoded viral FLICE inhibitory protein K13 interacts with a cytosolic

62 ly with the expression of KSHV-encoded viral FLICE inhibitory protein K13.

63 infection or on ectopic expression of viral FLICE inhibitory protein K13.

64 own that the antiapoptotic molecule cellular-FLICE-inhibitory protein long isoform [c-FLIP(L)] is nec

65 wn to encode proteins with DEDs (also called FLICE inhibitory proteins or vFLIPs) which have the abil

66 Knockdown of cellular FLICE inhibitory protein potentiates the caspase-depende

67 R4/TRAIL R1, Fas-associated death domain and FLICE-inhibitory protein proteins.

68 (KSHV) genomes encode a homolog of cellular FLICE-inhibitory proteins (termed v-FLIP) that activates

69 ption is regulated by the KSHV-encoded viral FLICE inhibitory protein (vFLIP) and by viral IFN regula

70 -associated herpesvirus (KSHV)-encoded viral FLICE inhibitory protein (vFLIP) enhances IRF4-mediated

71 ines, we have investigated the role of viral FLICE inhibitory protein (vFLIP) in this process.

72 characterized the role of KSHV-encoded viral FLICE inhibitory protein (vFLIP) K13 in the modulation o

73 -associated herpesvirus (KSHV)-encoded viral FLICE inhibitory protein (vFLIP) K13 is a potent activat

74 sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 was originally beli

75 he human herpes virus 8 (HHV8)-encoded viral FLICE inhibitory protein (vFLIP), also known as K13, is

76 Human herpesvirus 8 (HHV-8) encodes a viral FLICE inhibitory protein (vFLIP), called K13, with homol

77 e interferon converting enzyme or caspase 8 (FLICE) inhibitory protein (vFLIP) that prevents death re

78 Here, we have revealed the role of viral FLICE-inhibitory protein (vFLIP) in the initiation of PE

79 HHV8 encodes for a viral FLICE-inhibitory protein (vFLIP), designated K13, which

80 ation of B lymphocytes by KSHV-encoded viral FLICE-inhibitory protein (vFLIP).

81 levels of cellular inhibitors of apoptosis (FLICE inhibitory protein, X chromosome-linked inhibitor