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1 FTA loaded HNPs were prepared, characterized and evaluat
8 umor efficacy of farnesylthiosalicylic acid (FTA) loaded (lipid-cationic) lipid-PEG-PLGA hybrid nanop
9 encing protocols for poliovirus isolates and FTA cards using next-generation sequencing (NGS), aiming
10 other discrepant sample (CAPTIA negative and FTA-ABS positive [at an intensity of 3+], unblinded) was
11 icated that one patient (CAPTIA negative and FTA-ABS positive [minimally reactive], blinded) had poss
13 s (1) with active syphilis (reactive RPR and FTA-ABS) and (2) without current syphilis (nonreactive R
15 cules, CA], fluorescent treponemal antibody [FTA] assay [Zeus Scientific, Raritan, NJ], Treponema pal
16 ssay [TPHA]/fluorescent treponemal antibody [FTA] positive) and low-titer (n=249; RPR titer <1:8 and
17 fter a treatment period of 5days, IN applied FTA loaded HNPs achieved a significant decrease of 55.7%
19 ort of PFASs at a former fire training area (FTA) on Cape Cod, Massachusetts, where PFAS-containing a
20 15) but lower than for sera reactive on both FTA Abs and TPPA assays (12.37; P < .001) or for sera re
22 %) converted from nonreactive to reactive by FTA-ABS test; 4 (3.6%) were reactive by FTA-ABS tests bu
24 ent treponemal antibody absorption test (CSF-FTA-ABS) and a reactive CSF-TPPA did not differ signific
25 A sera and sera that were reactive on either FTA Abs or TPPA assays (2.19 vs 2.32; P = .15) but lower
26 eement ranged from 86.1% (83.7 to 88.2%) for FTA-ABS to 99.7% (99.0 to 99.9%) for Advia-Centaur CIA;
27 , the ability to obtain full PV genomes from FTA cards will aid in facilitating global poliovirus sur
30 d the potential utility of IN application of FTA loaded HNPs as a non-invasive approach in glioblasto
32 5 repeated doses of 500muM freshly prepared FTA loaded HNPs via IN or intravenous (IV) application.
33 es between results were resolved by repeated FTA-ABS testing (technologists were blinded to previous
37 sults indicate that unsaturated zones at the FTA and at hydraulically downgradient former domestic wa
39 ted (unblinded) as minimally reactive by the FTA method were subsequently interpreted (blinded) as no
45 nd low-titer (n=249; RPR titer <1:8 and TPHA/FTA positive) active syphilis and 950 uninfected women.
47 coveries than the procedure used for Whatman FTA DMPK-A, but the time needed for sample preparation w
51 commercial cards was also performed (Whatman FTA DMPK and Agilent Bond Elut DMS) using elution proced
52 pyrosequencing was combined with the Whatman FTA paper technology for the rapid extraction of fungal
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