ライフサイエンスコーパス: FTMS

1 Thus, in an FTMS ion cell with added electron trapping electrodes, c

2 ry and secondary alkoxides occurs under both FTMS and FA conditions.

3 ible obstacle to high-resolution analysis by FTMS.

4 m/z values below 1000 have been observed by FTMS of whole cells, this represents the first report of

5 cidated using HPLC ESI capillary-skimmer CID FTMS by correlating their fragmentation patterns with th

6 tial of MALDI-collision-induced dissociation-FTMS.

7 ially increases the capabilities of top down FTMS for the detailed structural characterization of lar

8 transform mass spectrometer (Orbitrap Elite FTMS).

9 Here we demonstrate an entirely FTMS-based analysis method with a 2.5-3.0-fold greater t

10 ESI-FTMS provides a universal method to achieve a direct and

11 igonucleotide products is mass mapped by ESI-FTMS analysis, which enables the unambiguous identificat

12 eated with ribonucleases and analyzed by ESI-FTMS to obtain the correct position of chemically modifi

13 on cross-linking strategies and top-down ESI-FTMS.

14 In particular, ESI-FTMS can be directly employed to monitor the conditions

15 High resolution ESI-FTMS analysis of the inactivated enzyme demonstrated tha

16 ion-Fourier transform mass spectrometry (ESI-FTMS) is employed in place of polyacrylamide gel electro

17 ion Fourier transform mass spectrometry (ESI-FTMS).

18 ion-Fourier transform mass spectrometry (ESI-FTMS).

19 ion-Fourier transform mass spectrometry (ESI-FTMS).

20 ion-Fourier transform mass spectrometry (ESI-FTMS).

21 oteins have been detected directly using ESI-FTMS (or MALDI-TOF), and the fractionation showed a peak

22 The application of an online FAIMS-FTMS coupling after photoionization for the analysis of

23 haracteristic is particularly beneficial for FTMS applications in which a sharp reduction of metastab

24 ight species presents a unique challenge for FTMS, as a result not only of the high cyclotron frequen

25 desorption/ionization (HP-MALDI) source for FTMS has recently been described.

26 s a control, accurate mass measurements from FTMS and collision-induced dissociation spectra, 11 nove

27 resolution precursor ion data obtained from FTMS mass spectra.

28 mprehensive analysis approach based on HILIC-FTMS was developed to concurrently examine polar metabol

29 e MeOH/ACN/Acetone extraction with the HILIC-FTMS method for metabolite profiling and smoking-related

30 The HILIC-FTMS method was developed using mixed standards of polar

31 HPLC-FTMS(n) analysis led to the annotation of 138 urinary me

32 d, namely, accurate mass fragmentation (HPLC-FTMS(n)) and mass-guided SPE-trapping of selected compou

33 The combination of the HPLC-FTMS(n) and HPLC-TOFMS-SPE-NMR platforms results in the

34 Hybrid FTMS instruments, such as the LTQ-FT and LTQ-Orbitrap, a

35 oughput proteomics measurements using hybrid FTMS instruments.

36 gnal detection periods typically employed in FTMS, viz., shorter than 6 s.

37 Selected method applications include FTMS analysis of crude oil fractions as well as tandem M

38 btained by analogous electrospray ionization-FTMS experiments, with no evidence of either metastable

39 clotron resonance mass spectrometry (nano-LC-FTMS).

40 tion of thousands of peptides in a single LC-FTMS analysis by comparing accurate molecular mass and L

41 rap-Fourier transform mass spectrometry (LTQ-FTMS).

42 rap-Fourier transform mass spectrometer (LTQ/FTMS).

43 ddition, the performance of the new HP-MALDI FTMS configuration and its potential application for hig

44 on is the evaluation of the current HP-MALDI FTMS configuration.

45 n Fourier transform mass spectrometry (MALDI FTMS) for neuropeptide analysis of complex tissue sample

46 MALDI-FTMS also provided information regarding E. coli lipids

47 MALDI-FTMS can clearly separate the molecular ion peaks from a

48 Finally, the potential of AP MALDI-FTMS for the high-resolution screening of complex mixtur

49 In our hands, AP MALDI-FTMS has enabled the analysis of complex peptide mixture

50 with minimal cleanup and monitored by MALDI-FTMS to elucidate the oligosaccharide sequence.

51 ons in the 5000 to 10,000 m/z range by MALDI-FTMS using whole cells.

52 It is shown that accurate mass MALDI-FTMS can be used to characterize specific ribosomal prot

53 Previous MALDI-FTMS studies of oligonucleotides had two limitations: (1

54 n-Fourier transform mass spectrometry (MALDI-FTMS).

55 n Fourier transform mass spectrometry (MALDI-FTMS).

56 With the anion dopants, the MALDI-FTMS signals are shown to have a linear relationship wit

57 tics of crustacean neuropeptides under MALDI-FTMS conditions and show how fragments formed by Asp-Xxx

58 nal structural information relative to MALDI/FTMS.

59 ionization (ESI) to a Fourier transform MS (FTMS).

60 sor ion scanning, higher resolution scans on FTMS instruments, and improved peptide quantitation.

61 ly can be realized using high-field Orbitrap FTMS and/or future generation of ultrahigh magnetic fiel

62 spite being initially developed for Orbitrap FTMS, the method is likewise applicable for ion cyclotro

63 acquired from 549 metabolites using Orbitrap FTMS(n).

64 analysis of petroleum samples with Orbitrap FTMS.

65 e I (42 kDa) yielded as many as 70 peptides, FTMS identification of the labeled peptide localized the

66 raw MS/MS data (obtained using a quadrupole-FTMS hybrid instrument) for one protein that differed fr

67 ewise applicable for ion cyclotron resonance FTMS.

68 a low-cost prototype for an external source FTMS instrument.

69 With the external ion source FTMS instrument, ions made by MALDI are injected at low

70 ch as a Fourier transform mass spectrometer (FTMS) allows accumulation of ions in the cell from m

71 source Fourier transform mass spectrometer (FTMS) equipped with matrix-assisted laser desorption/ion

72 n (ESI) Fourier transform mass spectrometer (FTMS) to characterize nucleic acid substrates modified b

73 eved by Fourier transform mass spectrometry (FTMS) allowed for the incorporation of substrates with s

74 solving Fourier Transform mass spectrometry (FTMS) allows to distinguish between most isobaric compou

75 ng both Fourier transform mass spectrometry (FTMS) and the flowing afterglow (FA) technique.

76 Fourier transform mass spectrometry (FTMS) enables comprehensive analysis of complex molecula

77 m ion cyclotron resonance mass spectrometry (FTMS) has been applied to the direct analysis of crustac

78 ed with Fourier transform mass spectrometry (FTMS) has proven to be a useful technique for the studie

79 ccuracy Fourier transform mass spectrometry (FTMS) is becoming increasingly attractive due to its spe

80 I) with Fourier transform mass spectrometry (FTMS) is described, and its significance for the high-re

81 tion of Fourier transform mass spectrometry (FTMS) to analysis of bacterial proteins directly from wh

82 n (ESI) Fourier transform mass spectrometry (FTMS) to assess the ability of a series of nucleic acid

83 olution Fourier transform mass spectrometry (FTMS), and fragmentation analysis.

84 (SPLC), Fourier transform mass spectrometry (FTMS), data-independent acquisition (DIA) with nozzle-sk

85 rved by Fourier transform mass spectrometry (FTMS).

86 n (ESI) Fourier transform mass spectrometry (FTMS).

87 n (ESI) Fourier transform mass spectrometry (FTMS).

88 (MALDI)-Fourier transform mass spectrometry (FTMS).

89 ly modified states from a single 90 min SPLC-FTMS run on approximately 0.5 mug of material.

90 Extension of such FTMS-based studies will allow the direct visualization o

91 However, the speed of tandem FTMS analysis severely limits the competitive advantage

92 inimized, and DNA ions can be trapped in the FTMS analyzer cell for greater than 50 s.

93 Use of dimethyl disulfide in the FTMS and evaluation of ion residence time in the FA lead

94 CAD or IRMPD of these ions collected in the FTMS cell.

95 pairs, vs 66 for CAD and 50 for IRMPD in the FTMS cell.

96 s are desorbed, ionized, and detected in the FTMS with >70 000 resolving power.

97 Furthermore, when the FTMS has a vibrationally cooled MALDI ion source, fragil

98 aneous detection of molecular hydrogen using FTMS and demonstrate the experimental conditions necessa

99 st intensely ionized serum metabolites using FTMS and tandem mass spectrometry was reported.

100 a 1.7 mm cryo-microprobe in combination with FTMS, exciton coupled CD, and stereochemical correlation

101 coupling of laser desorption techniques with FTMS was realized two decades ago, several different sol