ライフサイエンスコーパス: Fc receptor

1 as a previously unrecognized immunoglobulin Fc receptor.

2 ate or avoid effector cell functions through Fc receptors.

3 o the activated endothelium via cell surface Fc receptors.

4 of affinities for activatory and inhibitory Fc receptors.

5 nk between the innate pentraxins and humoral Fc receptors.

6 to antibodies binding to their low affinity Fc receptors.

7 gs and found FcRL4 and FcRL5 to be bona fide Fc receptors.

8 nction with structural homology to classical Fc receptors.

9 the in vivo function of the once mysterious Fc receptors.

10 lycosylation in the interaction of IgG1 with Fc receptors.

11 RL3) is a cell surface protein homologous to Fc receptors.

12 ing intraspinal complement and cells bearing Fc receptors.

13 c anti-HLA antibodies triggering their CD16a Fc receptors.

14 ic response in vivo when engaging activating Fc receptors.

15 f full-length Tau fibrils into microglia via Fc receptors.

16 nia (HIT) from cellular activation involving Fc receptors.

17 Indeed, Fc receptor activation is accompanied by increased expre

18 comprised an integrated pathway of TLR2 and Fc receptor activation, neutrophil migration, and inflam

19 Upon Fc receptor activation, Src-family kinase signaling lead

20 R binding assay sensitively detected greater Fc receptor activity to pandemic H1N1 hemagglutinin afte

21 e MHC fold has also been modified to perform Fc-receptor activity (e.g., FcRn) and for roles in host

22 sion on murine neutrophils, and by different Fc-receptor affinities for IgG across species.

23 ll molecule conjugate Fc-CGS retained potent Fc receptor and A(2A)R interactions and showed superior

24 xplained the ability of its two ligands, the Fc receptor and complement C1q, to bind to the top of it

25 Thus, thiolated EphA5-Fc receptor and ephrinA5-Fc ligand were conjugated into

26 ation and opsonization of pathogen result in Fc receptor and macrophage activation.

27 dritic cells (DC), which was mediated by the Fc receptor and was specific to trastuzumab.

28 Fc glycans influence the binding of IgG to Fc receptors and C1q, and are therefore important for Ig

29 at Asn-297 is critical for interactions with Fc receptors and complement and that glycosylation at As

30 Signal integration between activating Fc receptors and inhibitory signal regulatory protein al

31 grin (CD11b), and activated conformations of Fc receptors and integrins, have been proposed to report

32 Cell-cell signaling via both Fc receptors and NK-activating receptors led to measurab

33 one hand not engage conventional activating Fc receptors and on the other hand interact normally wit

34 ing between full-length IgG/Fc fragments and Fc receptors and the effect of chemical modifications on

35 n of the expression of complement receptors, Fc receptors, and F-actin formation after ANE treatment.

36 Expression of complement receptors, Fc receptors, and F-actin in ANE-treated neutrophils is

37 Fc receptors are crucial for innate immune activation.

38 Fc receptors are the cellular mediators of antibody func

39 ns and in particular, their interaction with Fc receptors as effectiveness of antibodies often depend

40 ound to a recombinant soluble human neonatal Fc receptor at pH 6.0 more strongly than CH2.

41 ng a primary infection facilitate entry into Fc receptor bearing cells during secondary infection, re

42 tibody-dependent enhancement of infection in Fc receptor-bearing cells at subneutralizing concentrati

43 rimary infection facilitate virus entry into Fc receptor-bearing cells during a subsequent secondary

44 nd EpCAM and a constant domain that recruits Fc receptor-bearing cells, notably monocytes, dendritic

45 nt (ADE) leading to increased replication in Fc receptor-bearing cells.

46 s capable of enhancing the DENV infection of Fc receptor-bearing cells.

47 t the antibody-mediated antiviral effects of Fc receptor-bearing leukocytes.

48 reduction of viral replication and enhanced Fc receptor binding and were consistent with transcripti

49 fully human anti-CD73, we demonstrated that Fc receptor binding augmented the production of proinfla

50 Removal of complement and/or Fc receptor binding did not affect h2G7 efficacy.

51 clonal antibodies that are mutated to reduce Fc receptor binding preserve beta-cell function and decr

52 ities, the ADCs have been engineered to lack Fc-receptor binding.

53 trial robustly boosted HIV-1 gp120-specific Fc receptor-binding antibodies and ADCC against HIV-1-in

54 ontact hypersensitivity, we found that a non-Fc receptor-binding isoform of Gal-1hFc, Gal-1hFc2, alle

55 amilies or can be induced indirectly through Fc receptors by antibodies mediating antibody-dependent

56 mokine, IL, TNF, MHC, immunoglobulin-binding Fc receptor, calcium-binding S100, matrix metalloprotein

57 have generated a mouse strain in which this Fc receptor can be conditionally deleted.

58 zation of different ligands such as mannose, Fc receptor, CD11c/CD 18, DEC-205 and DC-SIGN on DC for

59 agocytosis of IgG-opsonized bioparticles and Fc receptor CD16 and CD32 surface levels, a function, to

60 The Fc receptor CD16 is present on essentially all CD56(dim)

61 Presence of the immunoglobulin Fc receptor CD32 enhanced cellular responses, suggesting

62 (MoAb) is specific for the low-affinity IgG Fc receptor CD32B and effective in a human CD32B+ B-cell

63 oved in knockout mice lacking the inhibitory Fc receptor CD32b, nor against a Deltasmac P. berghei pa

64 cells modified to express the high-affinity Fc receptor (CD64) and CD86, the natural ligand of CD28

65 By binding to its specific Fc receptor CD89, IgA plays additional and poorly unders

66 intaining biological activity of the ActRIIB.Fc receptor chimera.

67 Apart from CHIR-AB, which functions as an Fc receptor, CHIR ligands are unknown.

68 ine-based activation motifs (ITAMs), such as Fc receptor common gamma (FcRgamma) and DNAX-activating

69 were higher in patients with a high affinity Fc-receptor compared to those with a lower affinity Fcga

70 Serum ADCC activity was analyzed using Fc receptor cross-linking, NK cell activation, and influ

71 e associative hypothesis, which posited that Fc receptor crosslinking produced the increased affinity

72 o the lung in naive mice in a mast cell- and Fc receptor-dependent manner.

73 ed breadth but may effect protection through Fc receptor-dependent processes, such as antibody-depend

74 antibodies induced death of AML cells in an Fc receptor-dependent way in the absence of cytotoxic le

75 The ablation of activating IgG Fc receptors did not ameliorate injury, implicating sube

76 Fc receptors endocytose modified nucleic acids bound to

77 stituents and produced interferon-gamma upon Fc-receptor engagement but not following combined interl

78 lation alters the affinity of antibodies for Fc receptors, evidence suggests that glycosylation is a

79 A label free immunosensor for detection of Fc receptors expressed on cell surface was developed and

80 ssed Kupffer cell phagocytosis by decreasing Fc receptor expression and Akt activation; however, it i

81 ration and this occurs due to maintenance of Fc receptor expression and cellular ATP content via the

82 ficantly higher than expression of all other Fc receptor family members.

83 ng the binding affinity of the Fc to diverse Fc receptor family members.

84 Blocking the IgA Fc receptor FcalphaRI abrogated phagocytosis and NET for

85 onstrated previously that triggering the IgA Fc receptor (FcalphaRI) on neutrophils results in neutro

86 essed, and the role of the high-affinity IgE Fc receptor (FcepsilonRI) in allergic sensitization was

87 IgE antibodies bind the high-affinity IgE Fc receptor (FcepsilonRI), found primarily on mast cells

88 tibodies interact with the high affinity IgE Fc receptor, FcepsilonRI, and activate inflammatory path

89 ations of which are mediated through its two Fc receptors, FcepsilonRI and CD23 (FcepsilonRII).

90 cell-to-cell spread and functions as an IgG Fc receptor (FcgammaR) that blocks the Fc domain of anti

91 variable, affecting binding to phagocyte IgG-Fc receptors (FcgammaR).

92 s dependent on the high-affinity IgG-binding Fc receptor (FcgammaRI) and the low-affinity IgG-binding

93 s effect was broadly recapitulated for other Fc receptors (FcgammaRI, FcgammaRIIA, FcgammaRIIB, and F

94 complement receptors (CR1, CR3, and CR4) and Fc receptors (FcgammaRII and FcgammaRIII) in a concentra

95 The uniquely human activating Fc receptor FcgammaRIIA promotes glomerular neutrophil a

96 Genetic variants of the inhibitory Fc receptor FcgammaRIIb have been associated with system

97 omote increased expression of the inhibitory Fc receptor FcgammaRIIB on effector macrophages.

98 ignaling is suppressed by the inhibitory IgG Fc receptor FcgammaRIIb; therefore, we reasoned that a t

99 The inhibitory low-affinity IgG Fc-receptor FcgammaRIIB is co-expressed on allergic effe

100 as long been known that the ITIM-bearing IgG Fc receptor (FcgammaRIIb, RIIb) is expressed on liver si

101 Genetic deficiency of the inhibitory Fc receptor, FcgammaRIIB (CD32b), has been shown to augm

102 ineate the effects of IgG and its inhibitory Fc receptor, FcgammaRIIb, on both de novo allergen sensi

103 Gs with enhanced affinity for the activating Fc receptor FcgammaRIIIA due to afucosylated Fc glycans

104 h is mediated in part through the activatory Fc receptor, FcgammaRIIIA.

105 (FcgammaRI) and the low-affinity IgG-binding Fc receptor (FcgammaRIV).

106 y to systemic anaphylaxis that relies on IgG Fc receptors (FcgammaRs).

107 The IgM Fc receptor (FcmuR) is the newest FcR, and coligation of

108 The association of an IgM-Fc receptor (FcmuR) with chronic lymphocytic leukemia (C

109 We identified the immunoglobulin M Fc receptor (FcmuR), also known as the Fas apoptotic inh

110 CH2 domain with corresponding modulation of Fc receptor (FcR) binding specificity from type I to typ

111 earance after vaccination was dependent upon Fc receptor (FcR) expression.

112 This implicates Fc-Fc receptor (FcR) interactions in affinity maturation, w

113 has accumulated supporting the importance of Fc receptor (FcR) ligation in antibody-mediated patholog

114 Little is known of the impact of Fc receptor (FcR) polymorphism in macaques on the bindin

115 rtion of immunoglobulin and the cell surface Fc receptor (FcR), an important area of the immune syste

116 ptor 3 (CR3), used by promastigotes, and the Fc receptor (FcR), used by amastigotes.

117 ies synergized through a mechanism combining Fc receptor (FcR)-dependent and FcR-independent stimulat

118 Accumulating evidence indicates a role for Fc receptor (FcR)-mediated effector functions of antibod

119 Here, the role of PLA(2)IValpha in Fc receptor (FcR)-mediated phagocytosis was investigated

120 Targeting an antigen to Fc receptors (FcR) can enhance the immune response to th

121 udies have demonstrated that targeting Ag to Fc receptors (FcR) on APCs can enhance humoral and cellu

122 s lacking the signaling chain of stimulatory Fc receptors (FcRgamma(-/-)) were unable to elicit arthr

123 ved, although it has been suggested that the Fc receptor FcRn may be involved in active antibody tran

124 The neonatal Fc receptor FcRn plays a critical role in the traffickin

125 The Fc receptor FcRn traffics immunoglobulin G (IgG) in both

126 f immunoglobulin G (IgG) binding to neonatal Fc receptor (FcRn) and Fcgamma receptor (FcgammaR) is im

127 gments lack the ability to bind the neonatal Fc receptor (FcRn) and have reduced half-lives.

128 gG antibodies on the binding to the neonatal Fc receptor (FcRn) as well as on FcRn-dependent pharmaco

129 G, through its Fc part, bind to the neonatal Fc receptor (FcRn) at low pH in the endosome after endoc

130 methionine residues and the loss of neonatal Fc receptor (FcRn) binding and complement-dependent cyto

131 onal studies by antigen binding and neonatal Fc receptor (FcRn) binding correlated very well with the

132 hree-dimensional structure of human neonatal Fc receptor (FcRn) bound concurrently to its two known l

133 The widely distributed neonatal Fc receptor (FcRn) contributes to maintaining serum leve

134 The neonatal Fc receptor (FcRn) directs the transfer of maternal immu

135 across the placenta by binding the neonatal Fc receptor (FcRn) expressed within the endosomes of the

136 The neonatal Fc receptor (FcRn) has been known to modulate IgG transp

137 The endothelial cellular neonatal Fc receptor (FcRn) has been suggested to play a central

138 maintained the binding affinity for neonatal Fc receptor (FcRn) in a pH-dependent manner.

139 involvement of immune complexes and neonatal Fc receptor (FcRn) in the emergence of ADAs in the case

140 Given the role of neonatal Fc receptor (FcRn) in transferring IgG across polarized

141 In light of the fact that the neonatal Fc receptor (FcRn) is a key regulator of albumin homeost

142 The neonatal Fc receptor (FcRn) is a major histocompatibility complex

143 The neonatal Fc receptor (FcRn) is a major regulator of IgG and album

144 Improved affinity for the neonatal Fc receptor (FcRn) is known to extend antibody half-life

145 Neonatal Fc receptor (FcRn) is the homeostatic receptor responsib

146 We also identify that the neonatal Fc receptor (FcRn) is upregulated in the cornea followin

147 eins for lysosomal degradation, the neonatal Fc receptor (FcRn) located at the brush border of the ap

148 Increasing affinity to neonatal Fc receptor (FcRn) may extend the pharmacokinetic half-l

149 The neonatal Fc receptor (FcRn) mediates the transport of IgG across

150 e found that PVIgGs associated with neonatal Fc receptor (FcRn) on the cell membrane, and the PVIgG-F

151 is delivered to fetuses through the neonatal Fc receptor (FcRn) pathway, which physiologically transf

152 interaction of the IgG1 Fc with the neonatal Fc receptor (FcRn) plays a critical role in maintaining

153 t affinity of IgG molecules for the neonatal Fc receptor (FcRn) receptor primarily arises from salt b

154 lf-life of IgG is controlled by the neonatal Fc receptor (FcRn) that interacts with the IgG Fc region

155 The neonatal Fc receptor (FcRn) transports maternal immunoglobulin (I

156 In contrast, in mice in which the neonatal Fc receptor (FcRn) was deleted, the half-life of rFIXFc

157 enhance interactions with the human neonatal Fc receptor (FcRn) without loss of the oligomeric struct

158 ent interaction between IgG and the neonatal Fc receptor (FcRn), as FcRn is the main homeostatic regu

159 on of the relevant receptor, namely neonatal Fc receptor (FcRn), by Calu-3 cell layers simulating the

160 tated by interaction with the human neonatal Fc receptor (FcRn), that promotes it as a highly attract

161 Genetic deletion of the neonatal Fc receptor (FcRn), which rescues albumin and IgG from l

162 at these sites is influenced by the neonatal Fc receptor (FcRn), whose role in protecting against inf

163 by instructing T reg formation via neonatal Fc receptor (FcRn)-mediated transfer and uptake of aller

164 ributed to its interaction with the neonatal Fc receptor (FcRn).

165 requires interaction of Fc with the neonatal Fc receptor (FcRn).

166 on proteins interact with the human neonatal Fc receptor (FcRn).

167 s pH-dependent interaction with the neonatal Fc receptor (FcRn).

168 o determine the contribution of the neonatal Fc-receptor (FcRn) in rat brain efflux employing two dif

169 We demonstrate here that the neonatal Fc receptor, FcRn, is expressed in female genital tract

170 The neonatal Fc receptor, FcRn, is responsible for the long half-life

171 The neonatal Fc receptor, FcRn, regulates the half-life of IgG in viv

172 Because SAP binds to Fc receptors (FcRs) expressed on monocytes, we investiga

173 Although Fc receptors (FcRs) for switched immunoglobulin (Ig) iso

174 ing downstream of the B-cell receptor (BCR), Fc receptors (FcRs), and toll-like receptors.

175 eutrophil activation through engagement with Fc receptors (FcRs).

176 -glycan in optimizing the interface with the Fc receptor for efficient binding.

177 egalovirus glycoprotein gp68 functions as an Fc receptor for host IgGs and can form antibody bipolar

178 FcalphaRI (CD89), the human Fc receptor for IgA, is highly expressed on neutrophil g

179 Immunoglobulin G (IgG) and the neonatal Fc receptor for IgG (FcRn) have an important function in

180 ived CD8(-)CD11b(+) DCs require the neonatal Fc receptor for IgG (FcRn) to conduct cross-presentation

181 ine kidney cells expressing the rat neonatal Fc receptor for IgG (FcRn), it significantly reduced vir

182 Fc receptor for IgG IIA (FcgammaRIIA)-mediated platelet

183 onal capacities of the TCR, the low-affinity Fc receptor for IgG, and the NKp30 and NKp46 natural cyt

184 Cell surface Fc receptor for IgM antibody (FcmuR) is the most recentl

185 However, the role of the putative Fc receptor for IgM, known as Toso/Faim3, has to this po

186 The neonatal Fc receptor for immunoglobulin (Ig)G (FcRn) protects mon

187 test this hypothesis, we targeted Hc to the Fc receptors for IgG (FcgammaRs) expressed by dendritic

188 red interactions between the antibody Fc and Fc receptors for IgG (FcgammaRs) to confer protection fr

189 ngs, and gene sets involved in phagocytosis, Fc receptor function, complement, and Ig regulation are

190 ridge the innate pentraxins and the adaptive Fc receptor functions.

191 The glycoprotein VI (GPVI)-Fc receptor gamma (FcRgamma) chain is the major platelet

192 s deficient in Mincle or its adapter protein Fc receptor gamma chain (FcRgamma) produced severely red

193 DCs from mice lacking the Fc receptor gamma chain exhibited an activated phenotype

194 ain the cytoplasmic region of the CD3zeta or Fc receptor gamma chain, effectively redirected T cell c

195 r tyrosine-based activation motif receptors: Fc receptor gamma chain, which is noncovalently associat

196 rane sequence that interacts with the common Fc receptor gamma subunit to initiate immune signaling.

197 The glycoprotein (GP) VI/Fc receptor gamma-chain complex is a central regulator o

198 n platelets, plays an important role in GPVI-Fc receptor gamma-chain complex-mediated platelet activa

199 In human platelets, Fc receptor gamma-chain IIa (FcgammaRIIa) has been ident

200 uced FcgammaRI effector functions, including Fc receptor gamma-chain signaling and intracellular calc

201 ased activation motif (ITAM) adaptor protein Fc receptor gamma-chain, even though the canonical ITAM

202 he immunoglobulin (Ig) receptor GPVI and the Fc receptor gamma-chain, which has an immunoreceptor tyr

203 ine phosphorylation events downstream of the Fc receptor gamma-chain-associated immunoreceptor tyrosi

204 ed T-cell receptor signaling, which utilizes Fc-receptor gamma-chain FcRgamma-Syk.

205 ivating Src family kinases (SFKs), DAP12 and Fc receptor-gamma (FcRgamma), spleen tyrosine kinase (Sy

206 e lectin 2, the receptor for podoplanin, and Fc receptor gammaII A, a low-affinity receptor for immun

207 unctional polymorphism in the inhibitory IgG-Fc receptor gene FcgammaRIIB influences intravenous immu

208 lactosylated IgA1 complexed with soluble IgA Fc receptor I (sCD89) and/or anti-hypogalactosylated-IgA

209 Polymorphisms in the immunoglobulin G Fc receptor II (FcGR) and tumor necrosis factor-alpha (T

210 expressing both hPF4+ and human platelet IgG Fc receptor IIA (FcgammaRIIA), infusion of the HIT-like

211 hisms within the gene encoding the human IgG Fc receptor IIA (hFcgammaRIIA) are associated with an in

212 s is based on the structures of low affinity Fc receptor in complex with Fc.

213 nd mouse pentraxins recognize major forms of Fc receptors in solution and on cell surfaces with affin

214 nces of the engagement of type I and type II Fc receptors in the context of infectious, autoimmune, a

215 The role of Fc receptors in the induction and progression of Crgn is

216 Parallel characterization of cell surface Fc receptors in the same samples by ELISA was also perfo

217 rm that PRN694 prevents T-cell receptor- and Fc receptor-induced cellular and molecular activation, i

218 igand-1 (PSGL-1, CD162), cytokine receptors, Fc receptors, integrins including alphaM integrin (CD11b

219 w, we discuss the mechanisms that govern IgG-Fc receptor interactions, highlighting the diversity of

220 the Fab domain to signal transduction via Fc-Fc receptor interactions.

221 our understanding of antibody recognition by Fc receptors is based on the structures of low affinity

222 ced IgG signaling through type I and type II Fc receptors is required for the control of proinflammat

223 We isolated the function of one Fc receptor isoform, Fc gammaRI, using IgG2a-coated targ

224 d-type, but not Fcgamma-receptor or neonatal Fc-receptor knock-out mice.

225 Fc receptor-like (FCRL) 5 regulates B cell Ag receptor s

226 Fc receptor-like (FcRL) proteins are a family of cellula

227 In contrast, Syk and Fc receptor-like 1 were downregulated.

228 Fc receptor-like 3 (FCRL3) is a cell surface protein hom

229 n the FCRL3 gene led to higher expression of Fc receptor-like 3 (FcRL3) on Treg cells and that FcRL3+

230 Fc receptor-like 4 (FcRL4) is expressed on the surface o

231 sine-based dual regulatory potential termed "Fc receptor-like 5" (FCRL5) was investigated to explore

232 erved with the putative inhibitory receptors Fc receptor-like-4 (FCRL4) and sialic acid-binding Ig-li

233 ipartite motif (TRIM) 21 as an intracellular Fc receptor linking cytosolic antibody recognition to th

234 arked genetic variability that exists in the Fc receptor locus.

235 e dependent on the CD4 activation, which was Fc receptor mediated.

236 refore, we hypothesized that vaccine-induced Fc receptor-mediated (FcR-mediated) Ab function is indic

237 ed as a novel mechanism in the modulation of Fc receptor-mediated cell activation in autoimmune disea

238 interactions, highlighting the diversity of Fc receptor-mediated effector functions that regulate im

239 may not depend on complement activation and Fc receptor-mediated effector functions.

240 ng specificities determines the magnitude of Fc receptor-mediated effector functions.

241 Equally cross-reactive Fc receptor-mediated functional activities, including AD

242 macrophages, expression of Fcgr3-rs inhibits Fc receptor-mediated functions, because WKY bone marrow-

243 crescent formation, macrophage infiltration, Fc receptor-mediated macrophage activation and cytokine

244 lity, mediated partly through differences in Fc receptor-mediated macrophage activation.

245 associated with decreased apoptotic cell and Fc receptor-mediated macrophage clearance.

246 rgn1 BMDMs showed a significant reduction in Fc receptor-mediated oxidative burst, phagocytosis of op

247 acts with the common Fc-gamma chain but that Fc receptor-mediated phagocytosis and signaling are defe

248 The roles of Fc receptor-mediated protective antibody responses are g

249 ve roles in regulating TCR and high-affinity Fc receptor-mediated signaling and cellular function.

250 Fc-receptor-mediated endocytosis and the endosome/autoph

251 Dasatinib completely blocked integrin- and Fc-receptor-mediated neutrophil functions, with the lowe

252 o the related CD1a, CD1b, CD1c, and neonatal Fc receptor molecules were absent from the surfaces of b

253 uires binding of the antibody to a cytosolic Fc receptor named tripartite motif containing 21 (TRIM21

254 dications, while the newer therapies include Fc receptor-non-binding CD3-specific antibodies, IL-12/2

255 ermine whether two courses of teplizumab, an Fc receptor-nonbinding anti-CD3 monoclonal antibody, red

256 The expression of Fc receptors, of Akt phosphorylation, of p38 MAPK phosph

257 inding between Staphylococcus aureus and the Fc receptor on macrophage.

258 The Fc receptor on NK cells, FcgammaRIIIA (CD16), has been e

259 ne marrow chimeras, we found that activating Fc receptors on basophils were required for protective i

260 We investigated the role of Fc receptors on basophils, the antibody isotypes IgG1 an

261 nduce tissue injury via either engagement of Fc receptors on effector cells or via complement activat

262 tion between RA IgG immune complexes and IgG Fc receptors on immune cells.

263 ugh the interaction of the Fc glycan and the Fc receptors on immune cells.

264 Immune complex-mediated activation of Fc receptors on infiltrating blood-borne cells and tissu

265 cancer cell growth by engaging high-affinity Fc receptors on monocytes and macrophages; however, the

266 otein C-reactive protein (CRP), a ligand for Fc receptors on phagocytes, enhances antibody-mediated p

267 gG (IVIG) was administered to manipulate the Fc receptor or when (124)I-huA33 was given via hepatic a

268 were protective in mice lacking complement, Fc receptors, or both, suggesting that they operate inde

269 esponse of cells to growth factor receptor-, Fc receptor-, or TLR-mediated signaling.

270 Interestingly, the number of mouse Fc-receptor-positive cells was significantly increased i

271 Interestingly, the number of mouse Fc-receptor-positive cells was significantly increased i

272 d through cold ischemia via interaction with Fc-receptor-positive cells.

273 d that polymorphisms of two immunoglobulin G Fc receptors predict rituximab response, presumably beca

274 nomic and phenotypic analyses of FCGR3A/CD16 Fc-receptor profiles were compared in CAV-positive (n=52

275 Despite the diversity of the Fc receptor proteins, IgG ligands, and potential respond

276 vian yolk sac, and represents a new class of Fc receptor related to the mammalian mannose receptor fa

277 enhanced the levels of antibody binding and Fc receptor signaling mediated by HIV-positive-patient-d

278 duction that are likely related to inhibited Fc receptor signaling within macrophages in diseased glo

279 e (BTK) is important for B cell development, Fc receptor signaling, and macrophage polarization.

280 hogens by immune cells triggers both TLR and Fc receptor signaling.

281 hesion molecules intrinsic to the activating Fc-receptor signalling pathway, namely immune semaphorin

282 Absent neonatal Fc receptor surface expression led to low serum IgG and

283 ose IgG-opsonized bioparticles by decreasing Fc receptor surface levels, a mechanism previously thoug

284 le, and that of the fragment crystallizable (Fc) receptors that bind them, in driving local inflammat

285 al models at the level of both Abs and their Fc-receptors, that might provide some answers.

286 By engaging the neonatal Fc receptor the Fc domain extends the in vivo lifespan o

287 cytoplasmic domain, the platelet FcgammaRIIa Fc receptor, the protein-tyrosine kinase Syk, and phosph

288 man IgGs and attracted immune cells carrying Fc receptors to tumor cells that expressed p185(her2/neu

289 Fc receptors transport maternal antibodies across epithe

290 rom inside cells by activating the cytosolic Fc receptor TRIM21.

291 In contrast to other Fc receptors, TRIM21 shows remarkably broad isotype spec

292 tau-associated antibodies and the cytosolic Fc receptor tripartite motif protein 21 (TRIM21).

293 tivities by engaging two distinct classes of Fc receptors (type I and type II) on the basis of the tw

294 immune complexes, it is also plausible that Fc receptor usage patterns may regulate the immune respo

295 formed by IgE and its evolutionarily related Fc receptors, we conclude that this mechanism is general

296 n the expression of complement receptors and Fc receptors were examined using an immunofluorescence s

297 hat this effect is dependent on the neonatal Fc receptor, which rescues the dissociated antibody in t

298 x binding mechanism is distinct from that of Fc receptors, which bind through the Fc.

299 sequence (Fcgr3-rs) is a novel rat-specific Fc receptor with a cytoplasmic domain 6 amino acids long

300 ptor I (FcgammaRI or CD64) is the sole human Fc receptor with high affinity for monovalent IgG.