ライフサイエンスコーパス: Felis

1 ure (single monomer vs. tandemly repeated in Felis).

2 ainly CD4(+) for H. pylori and CD8(+) for H. felis.

3 similar (97 to 99%) to "H. heilmannii" or H. felis.

4 eukin-10-deficient (IL-10(-/-)) mice with H. felis.

5 and the mice were orally inoculated with H. felis.

6 type (WT) C57BL/6 mice were infected with H. felis.

7 ion with Helicobacter pylori or Helicobacter felis.

8 nisms and evaluate the immune response to H. felis.

9 cts mice against challenge with Helicobacter felis.

10 e to be designated a new species, Rickettsia felis.

11 nd congenic mice with a single isolate of H. felis.

12 h either Helicobacter pylori or Helicobacter felis.

13 a after infection of mice with H pylori or H felis.

14 n and IL-8Tg mice infected with Helicobacter felis.

15 urease B (ureB) gene of H. heilmannii and H. felis.

16 re positive for H. heilmannii and two for H. felis.

17 is of the sialome of cat flea Ctenocephaides felis.

18 og (2) genotypes, C. meleagridis (7), and C. felis (1).

19 s, 20 were qPCR positive for FHV-1, 7 for M. felis, 5 for FCV, 1 for C. felis, and 0 for B. bronchise

20 ridis (17 persons), C. canis (6 persons), C. felis (6 persons), and C. suis (1 person) infection.

21 than to that of the California strain of H. felis (84%).

22 ted to that of the Ohio-Florida strain of H. felis (89%) than to that of the California strain of H.

23 The relationship of Helicobacter felis, a bacterium observed in the stomachs of cats, to

24 solates of A. fumigatus, A. viridinutans, A. felis, A. pseudoviridinutans, and A. wyomingensis but wa

25 vitro studies demonstrated that Helicobacter felis activates complement in normal mouse serum but not

26 erum from Rag2(-/-) mice, indicating that H. felis activates complement through the classical pathway

27 After treatment with Helicobacter felis Ag, DC were polarized to secrete interleukin-6 as

28 fection in a host infected with Helicobacter felis alters the natural outcome of T. gondii infection,

29 acteria were closely related to Helicobacter felis, although there was heterogeneity among the sequen

30 ri, Helicobacter heilmannii and Helicobacter felis among others.

31 Cytauxzoon felis, an emerging virulent protozoan parasite that infe

32 ar to those originating from C. psittaci, C. felis and C. caviae.

33 C57BL/6 (-/-)] were orally infected with H. felis and examined longitudinally using routine histolog

34 L/6-T-bet knockout (KO) litter mates with H. felis and examined the bacterial colonization, immune re

35 Chlamydophila felis and feline herpesvirus (FHV) are pathogens commonl

36 NS-GAS mice) were infected with Helicobacter felis and given the CCK2/gastrin receptor antagonist YF4

37 ori and non-Helicobacter pylori organisms H. felis and H. heilmannii and analyzed the association bet

38 and H. pylori and 1(20%) coinfected with H. felis and H. pylori (p = 0.15).

39 and H. pylori and 3(60%) coinfected with H. felis and H. pylori (p = 0.66).

40 that the major protein bands of Helicobacter felis and Helicobacter bizzozeronii, two Helicobacter sp

41 PRIL Tg mice were infected with Helicobacter felis and Helicobacter pylori and compared with noninfec

42 uce protective immunity against Helicobacter felis and Helicobacter pylori infection in mice.

43 C57BL/6 mice were infected with Helicobacter felis and received bacterial eradication therapy after 2

44 currence of high relative copy numbers of C. felis and severe clinical signs in all cats was seen.

45 complex prevents gastric colonization by H. felis and the inflammatory response.

46 ently (e.g., Bartonella henselae, Rickettsia felis), and their mechanisms of transmission and impact

47 r FHV-1, 7 for M. felis, 5 for FCV, 1 for C. felis, and 0 for B. bronchiseptica.

48 re positive for FHV, 97 were positive for C. felis, and 16 were positive for both pathogens.

49 e orally infected with a single strain of H. felis, and 2 and 11 weeks after infection, the mice were

50 argeted mice were infected with Helicobacter felis, and a series of adoptive transfer experiments was

51 virus (FCV), Mycoplasma felis, Chlamydophila felis, and Bordetella bronchiseptica.

52 diarrhea, only infections with C. canis, C. felis, and subtype family Id of C. hominis were associat

53 of the H. muris strains, four strains of H. felis, and two strains of Eperythrozoon suis were sequen

54 atusRickettsia amblyommii,"R. montanensis,R. felis, andR. belliiwere frequently identified species, a

55 ins of H. pylori, as well as in Helicobacter felis, another member of the same genus.

56 Sera were also evaluated for H. felis antibody by ELISA.

57 H. felis antral colonization remained stable over time amon

58 th C. hominis and C. parvum; C. canis and C. felis are responsible for only a small number of cases.

59 of recent reports have implicated Rickettsia felis as a human pathogen, paralleling the increasing de

60 d-type mice were colonized with Helicobacter felis, as a model of human H. pylori infection.

61 after challenge with either H. pylori or H. felis, as confirmed by the complete absence of any bacte

62 ygous mice were inoculated with Helicobacter felis at 6 weeks of age and compared at various time poi

63 e-linked immunosorbent assay (ELISA) with H. felis ATCC 49179 antigen were performed with 101 serum s

64 nd for 1 year after oral inoculation with H. felis (ATCC 49179).

65 C. felis became undetectable in some of the cats during or

66 le when paired with the MAT1-1 isolate of A. felis but not with any of the other species.

67 d IL-10(-/-) mice infected with Helicobacter felis by gastric lavage.

68 L/6 x 129SvEv)F1] mice were infected with H. felis by oral gavage and were assessed histologically an

69 H. felis can induce a hypertrophic gastropathy in the C57BL

70 obacter pylori (H. pylori) in domestic cats (Felis cattus) less than 2 years of age has been well des

71 mental and theoretical analysis reveals that Felis catus exploits fluid inertia to defeat gravity and

72 present predominantly in one felid species: Felis catus GHV 1 (FcaGHV1) in domestic cats, Lynx rufus

73 e disease and mortality in the domestic cat (Felis catus) and serves as a natural model for HIV infec

74 It is known that domestic cat (Felis catus) APOBEC3Z3 (A3Z3), the ortholog of human APO

75 direction and retinal disparity in the cat (Felis catus) are all strongly related to the organizatio

76 nce spanning 758,291 bp of the domestic cat (Felis catus) extended and classical class II region.

77 We show that the domestic cat (Felis catus) laps by a subtle mechanism based on water a

78 Urban domestic cat (Felis catus) populations can attain exceedingly high den

79 ated the susceptibility of the domestic cat (Felis catus) to CWD infection experimentally.

80 nal referentiality in a common domestic cat (Felis catus) vocalization, the authors conducted 2 exper

81 and DRB gene homologues of the domestic cat (Felis catus) were cloned and sequenced to compare the pa

82 stic felids, vocalizations by domestic cats (Felis catus) were compared with cries by their closest w

83 entify felid GHVs, we screened domestic cat (Felis catus), bobcat (Lynx rufus), and puma (Puma concol

84 GHVs present in the blood of domestic cats (Felis catus), bobcats (Lynx rufus), and pumas (Puma conc

85 uenced the red and green opsin cDNAs of cat (Felis catus), horse (Equus caballus), gray squirrel (Sci

86 of FIV have been described for domestic cat (Felis catus), puma (Puma concolor), lion (Panthera leo),

87 several closely related to the domestic cat (Felis catus).

88 auses an AIDS-like disease in domestic cats (Felis catus).

89 roduced species, particularly the feral cat, Felis catus, and European red fox, Vulpes vulpes, and ch

90 bp mitochondrial genome of the domestic cat, Felis catus, has been sequenced and conforms largely to

91 comparative gene maps, the feline gene map (Felis catus, Order Carnivora, 2N = 38) displays the high

92 Following H. felis challenge, addition of the adjuvant CpG ODN provid

93 FHV-1), feline calicivirus (FCV), Mycoplasma felis, Chlamydophila felis, and Bordetella bronchiseptic

94 H. felis colonization also was increased in Duoxa(+/-) mice

95 atment did not alter the overall level of H. felis colonization but did result in significant down-re

96 H. felis colonization was significantly greater in the iNOS

97 onounced gastric atrophy after short-term H. felis colonization with a similar extent of preneoplasia

98 H. felis colonized the mucus layer in the stomachs of Duoxa

99 A high percentage of free-ranging pumas (Felis concolor) are infected with feline lentiviruses (p

100 rresponding transmembrane segments of the H. felis CopA pump were identified by hydrophobicity analys

101 ch single-nucleotide polymorphisms in the C. felis cytb gene had been identified.

102 The C. felis cytb genotype cytb1 is associated with increased s

103 69 cats with cytauxzoonosis for which the C. felis cytb genotypes had been characterized previously.

104 design a PCR panel that could distinguish C. felis cytb1 from other cytochrome b genotypes.

105 The PCR panel identified C. felis cytb1 with 100% sensitivity and 98.2% specificity.

106 tovaquone, a ubiquinone analogue, targets C. felis cytochrome b (cytb), of which 30 unique genotypes

107 We characterized the C. felis cytochrome b gene (cytb) in cats with cytauxzoonos

108 C57BL/6 mice inoculated with Helicobacter felis develop gastritis by 4 weeks.

109 felis were monitored for the presence of C. felis DNA on ocular swabs by using real-time PCR and for

110 otor task and sitting quietly in adult cats (Felis domestica).

111 st mite (Dermatophagoides farinae), and cat (Felis domesticus) allergens in home dust samples, and sp

112 The cat isocortex (Felis domesticus) shows a similar structure.

113 now we add the successful cloning of a cat (Felis domesticus) to this list.

114 Infection of IL-10(-/-) mice with H. felis elicited a severe chronic gastritis and a greatly

115 Infection of IL-10(-/-) mice with H. felis elicited severe gastritis.

116 The data suggest that H. pylori and H. felis employ conserved mechanisms of ATPase-dependent co

117 vitro, induction of oxidative defense by H. felis failed to prevent a direct bacteriostatic effect a

118 tion to its annoyance to pets and humans, C. felis felis is responsible for flea bite allergy dermati

119 The cat flea, Ctenocephalides felis felis, is the most important ectoparasite of domes

120 by experimental infection with Helicobacter felis, followed by antibiotic eradication therapy and su

121 mice chronically infected with Helicobacter felis for 2 mo with the SOM analogue octreotide resolved

122 eporter mice were infected with Helicobacter felis for 3 and 8 weeks.

123 ions from male C57BL/6 mice infected with H. felis for 6 months.

124 el(-/-) mice were infected with Helicobacter felis for 6 weeks or 12 months.

125 C57BL/6 wild-type mice were infected with H. felis for either 12 or 18 months.

126 The sequences of two strains of H. felis from cats in California were identical, as were th

127 enzymes DdeI and MnlI for distinguishing H. felis from closely related bacteria was examined.

128 6-bp DNA fragment of the 16S rRNA gene of H. felis from each of four experimentally infected cats at

129 rs from the numt previously described in the Felis genus in: (1) chromosomal location (F2-telomeric r

130 und in the genomes of related species of the Felis genus, previously shown to harbor enFeLVs.

131 elicobacter spp. revealed that all except H. felis grew in serum-free, unsupplemented F-12.

132 ld-type mice were infected with Helicobacter felis (H. felis) to induce gastritis.

133 ther helicobacters (H. canis, H. cineadi, H. felis, H. mustelae, H. nemestrinae, H. pullorum, H. pylo

134 te substantial antigenic homology between H. felis, H. pylori, and H. bizzozeronii.

135 the "H. heilmannii"-like organisms (HHLO) H. felis, H. salomonis, and H. bizzozeronii.

136 , or both, produced a specific fecal anti-H. felis IgA response, with the highest IgA levels occurrin

137 ection with T. gondii alters the specific H. felis immune response, converting a previously resistant

138 ombination developed increased serum anti-H. felis immunoglobulin G (IgG).

139 0 (57%), H. heilmannii in 17/250 (6%) and H. felis in 10/250 (4%), respectively.

140 , paralleling the increasing detection of R. felis in arthropod hosts across the globe, primarily in

141 whole-cell sonicate vaccine of Helicobacter felis in conjunction with cholera toxin as a mucosal adj

142 Cellular stress was induced with IR and H felis in Ikkbeta(Deltastom), Ikkbeta(F/F), and cis-NF-ka

143 The acquisition and persistence of R. felis in mosquitoes was demonstrated by quantitative PCR

144 ed with a Florida isolate of Haemobartonella felis in order to collect organisms and evaluate the imm

145 Challenge with H. felis increased the inflammatory response in the gastric

146 Infection with H. felis induced expression of Duox2 and Duoxa2 in the stom

147 the role of CD73 in regulating Helicobacter felis-induced gastritis and colonization.

148 out mice have increased susceptibility to H. felis-induced gastritis, with enhanced gastric inflammat

149 d p53 hemizygous mouse model of Helicobacter felis-induced gastritis.

150 ced peritonitis, DSS-induced colitis, and H. felis-induced gastritis.

151 n of noggin in mice increased H pylori- or H felis-induced inflammation and epithelial cell prolifera

152 ative of an impaired Th1 component of the H. felis-induced inflammatory response when the influence o

153 of SPEM to the neoplastic process in the H. felis -infected C57BL/6 mouse, we have now studied the a

154 Natural bites from R. felis-infected An. gambiae were able to cause transient

155 lesterol levels were observed between the H. felis-infected and -uninfected iNOS-/- mice in this stud

156 ddition, a group of mosquitoes was fed on R. felis-infected BALB/c mice.

157 Gastritis in H. felis-infected CD73-/- mice was significantly worse than

158 In contrast, H. felis-infected IL-10(-/-) mice develop a severe hyperpla

159 In contrast to wild-type mice, H. felis-infected IL-10(-/-) mice had a marked increase in

160 H. felis-infected IL-10(-/-) mice may provide a model with

161 cter-associated gastric carcinogenesis in H. felis-infected mice on a uniform C57BL/6 background hous

162 ic Pdx1 expression was observed in either H. felis-infected or DMP777-treated mice.

163 nths of age, in comparison with Helicobacter felis-infected wild-type littermates.

164 us metaplasia in the fundic mucosa, while H. felis-infected wild-type mice had severe atrophic and me

165 cant reduction of gastric inflammation in H. felis-infected, as well as immunized/challenged, mice.

166 itude between 12 and 15 months of chronic H. felis infection (P = 0.167).

167 jective of this study was to determine if H. felis infection alters gastric histopathology, proinflam

168 Both H. felis infection and K-ras mutation induced upregulation

169 adjuvant and examined for the presence of H. felis infection and leukocyte infiltration into the gast

170 R is a sensitive technique for monitoring C. felis infection and the response to antibiotic treatment

171 Ure produces a long-lasting inhibition of H. felis infection but that residual bacteria may produce a

172 Chronic H. felis infection did not alter these proportions, but ora

173 infection, but in GECs by IR or long-term H felis infection during progression to dysplasia.

174 Persistent Helicobacter felis infection in (C57BL/6 x 129SvEv)F1 mice induces ch

175 These findings indicate that H. felis infection in cats induces lymphoid follicular hype

176 cilitated diagnosis and discrimination of H. felis infection in cats.

177 n the recent report of high prevalence of R. felis infection in patients with "fever of unknown origi

178 y regulate the epithelial consequences of H. felis infection in the stomach, while c-Rel-mediated sig

179 H. felis infection leads to increased apoptosis and altered

180 ogenesis, and novel experiments involving H. felis infection of bone marrow transplanted irradiated m

181 veloped to detect and quantify Chlamydophila felis infection of cats.

182 Helicobacter felis infection of INS-GAS mice led to accelerated (< or

183 s of the antrum and pyloric junction, but H. felis infection of the Apc mutant mouse does not lead to

184 on between hypergastrinemia and Helicobacter felis infection on gastric corpus carcinogenesis in FVB/

185 emia in mice can synergize with Helicobacter felis infection to induce gastric carcinoma.

186 A mouse model of Helicobacter felis infection was used to study possible genetic deter

187 T-bet KO mice respond to H. felis infection with a markedly blunted IL-1beta and TNF

188 as upregulated in myeloid cells with acute H felis infection, but in GECs by IR or long-term H felis

189 Within 4 weeks of H. felis infection, there are striking alterations in the c

190 emia, and possible synergy with Helicobacter felis infection, were investigated in insulin-gastrin (I

191 was observed in BALB/c and C3H/HeJ after H. felis infection, whereas sPLA2 expression was absent in

192 Within 4 weeks of H. felis infection, wild-type mice develop a mild, focal ch

193 with oral doxycycline will not eliminate C. felis infection.

194 a competent immune response to Helicobacter felis infection.

195 odel of Helicobacter pylori and Helicobacter felis infection.

196 ecies has the potential to be a vector of R. felis infection.

197 protection of the gastric mucosa against H. felis infection.

198 ion-mediated protection against Helicobacter felis infection.

199 une-mediated gastric pathology seen after H. felis infection.

200 evaluated histologically for magnitude of H. felis infection.

201 epithelial pathology even 12 months after H. felis infection.

202 not increase the risk of H. heilmannii or H. felis infection.

203 by DMP-777 treatment, L-635 treatment, or H felis infection.

204 to ionizing radiation (IR) and Helicobacter felis infection.

205 the cytokine environment during Helicobacter felis infection.

206 be useful for the serologic diagnosis of H. felis infections in cats.

207 characterized the cat flea (Ctenocephalides felis) innate immune response to R. typhi Initially, we

208 The stomachs of all five H. felis-inoculated cats became colonized, as determined by

209 elopment of gastric atrophy and cancer in H. felis/INS-GAS mice, while the proton pump inhibitor show

210 Cytauxzoon felis is a virulent, tick-transmitted, protozoan parasit

211 t was concluded that gastritis induced by H. felis is associated with increased HbA(1c) levels in the

212 d Helicobacter that is closely related to H. felis, is associated with little or no gastritis, and sh

213 Using the Helicobacter felis mouse model or H. pylori mouse model, both prophyl

214 We have utilized the C57BL/6 Helicobacter felis mouse model to critically analyze the role of the

215 employed the well-characterized Helicobacter felis-mouse model.

216 African black-footed cats (Felis nigripes) are endangered wild felids.

217 Three were strains of H. felis, one was H. bilis, and one was a novel helicobacte

218 own that infection of mice with Helicobacter felis or induction of acute parietal cell loss with the

219 fed with either blood meal infected with R. felis or infected cellular media administered in membran

220 could be specifically attributed to FCV, M. felis, or C. felis were seen, although interpretation in

221 ples from 8 children with C. meleagridis, C. felis, or C. parvum dog genotype were tested for anti-hu

222 R assay, the minimum detectable number of H. felis organisms was determined to be between 50 and 704.

223 tly up-regulated in WT mice infected with H. felis (P < 0.05) but were slightly elevated or were at b

224 h1-associated IgG2c antibody responses to H. felis (P <0.0003); the Th2-associated IgG1 responses wer

225 All the H. heilmannii and H. felis PCR positive patients were also positive for H. py

226 Blood for H. felis purification was repeatedly collected from splenec

227 r to Gastrospirillum hominis or Helicobacter felis (referred to as gastrospirilla).

228 th 7 and 14 days of doxycycline decreased C. felis relative copy numbers and clinical signs rapidly.

229 ed with Helicobacter pylori and Helicobacter felis, respectively.

230 are caused by host-specific C. canis and C. felis, respectively.

231 cell-deficient TCRbetadelta-/- mice with H. felis resulted in high levels of colonization, but no de

232 on in the body of the stomach, lower anti-H. felis serum IgG antibody responses (although both the wi

233 nfected animalls developed sustained anti-H. felis serum immunoglobulin G antibody responses.

234 enetic linkage (GL) map of the domestic cat (Felis silvestris catus).

235 ment of paw preferences in the domestic cat, Felis silvestris catus, is explored.

236 closest wild relative, the African wild cat (Felis silvestris lybica).

237 979 domestic cats and their wild progenitors-Felis silvestris silvestris (European wildcat), F. s. ly

238 group represents a distinctive subspecies of Felis silvestris.

239 ed by 16S rRNA gene sequencing as Mycoplasma felis (six cases) and Mycoplasma gateae (one case).

240 ed controls (P = 0.0008 and P = 0.002 for H. felis sonicate and CT, respectively).

241 tection induced by oral immunization with H. felis sonicate and CT.

242 e proportions, but oral immunization with H. felis sonicate plus cholera toxin (CT) or with CT alone

243 this sequence data, we designed a set of H. felis-specific primers.

244 E. suis being most similar to that of the H. felis strain from California.

245 ession of the H2O2-inducible katA gene in H. felis that colonized Duoxa(-/-) mice, compared with that

246 One year after infection with H. felis, the wild-type and p53 hemizygous mice showed seve

247 critical regulator of R. typhi burden in C. felis These data suggest that targeting the IMD pathway

248 The untreated cats remained positive for C. felis throughout the trial; clinical signs were most sev

249 control mice were infected with Helicobacter felis to create a model of Helicobacter pylori infection

250 ce were infected with Helicobacter felis (H. felis) to induce gastritis.

251 While bioinformatics analysis of the C. felis transcriptome identified homologs to all of the Dr

252 Four SPF H. felis-uninfected cats served as controls.

253 ori and H. heilmannii was 17(6%) and with H. felis was 10(4%), respectively.

254 R. felis was also found in the cotton used for sucrose feed

255 The 16S rRNA gene of Haemobartonella felis was amplified by using universal eubacterial prime

256 R. felis was detected in mosquito feces up to day 14.

257 cing of PCR products of H. heilmannii and H. felis was done.

258 y cytokine expression, or colonization of H. felis was evaluated in CD73-deficient (CD73-/-) mice or

259 H. felis was inoculated by gastric intubation into SPF C57B

260 The prevalence of H. heilmannii and H. felis was low in our patients with dyspepsia.

261 Furthermore, R. felis was visualized by immunofluorescence in salivary g

262 er bacteria (H. pylori, H. hepaticus, and H. felis) was mediated not by TLR4 but rather by TLR2.

263 SvEv (B6129) mice infected with Helicobacter felis, we conducted a study to characterize H. pylori in

264 rons of Helicobacter pylori and Helicobacter felis were cloned by gene library screening.

265 ), IgG2a, and IgG2c antibody responses to H. felis were determined.

266 . pylori, an H. pylori cagE(-) mutant, or H. felis were killed 2-24 weeks postchallenge.

267 Fifteen cats infected with Chlamydophila felis were monitored for the presence of C. felis DNA on

268 cifically attributed to FCV, M. felis, or C. felis were seen, although interpretation in this cohort

269 rgastrinemic mice infected with Helicobacter felis were studied at multiple stages of gastric dysplas

270 l disease (colitis), and antibody levels (H. felis) were examined.

271 Helicobacter felis, which does not express CagA or VacA, causes chron

272 als immunized intranasally with sonicated H. felis with CT and CpG.

273 e were immunized with sonicated Helicobacter felis with CT and/or CpG ODN adjuvants.