ライフサイエンスコーパス: Fusobacterium

1 l lineages, such as Aquifex, Thermotoga, and Fusobacterium.

2 ies, e.g., Selenomonas noxia, F. alocis, and Fusobacterium.

3 s (39), Campylobacter (8), Clostridium (96), Fusobacterium (12), Leptotrichia (8), Mobiluncus (8), Pe

4 were B. forsythus (59%), spirochetes (54%), Fusobacterium (41%), P. micros (39%), and P. gingivalis

5 ed organisms for AP were B. forsythus (83%), Fusobacterium (80%), spirochetes (79%), P. gingivalis (5

6 ponding data for RP were B. forsythus (85%), Fusobacterium (83%), P. gingivalis (60%), spirochetes (5

7 c regression was used to compare tertiles of Fusobacterium abundance.

8 n between local cytokine gene expression and Fusobacterium abundance.

9 In this study, a novel adhesin, FadA (Fusobacterium adhesin A), was demonstrated to bind to th

10 s, B. forsythus, and Capnocytophaga species, Fusobacterium alocis, Actinomyces odontolyticus, Actinom

11 We also confirmed previous reports on Fusobacterium and CRC in 10 CRC tumor tissues and 9 matc

12 33, p = 0.06 while it was 0.44, p = 0.01 for Fusobacterium and IL-10.

13 adenocarcinomas were found to retain viable Fusobacterium and its associated microbiome through succ

14 olonization of human colorectal cancers with Fusobacterium and its associated microbiome-including Ba

15 Two main additional taxa, Fusobacterium and Parvimonas, correlated with the clinic

16 Firmicutes, Proteobacteria, Actinobacteria, Fusobacterium, and Bacteroidetes, with the first 3 phyla

17 reviously (Prevotella, Sneathia, Aerococcus, Fusobacterium, and Gemella) as well as several novel tax

18 ed in members of the Haemophilus, Neisseria, Fusobacterium, and Porphyromonas species and the Sphingo

19 s as a potential treatment for patients with Fusobacterium-associated colorectal cancer.

20 elial cells (HOECs) and designated it FAD-I (Fusobacterium-associated defensin inducer).

21 taxa of lower abundance including the genera Fusobacterium, Atopobium, Gluconacetobacter, Hydrogenoph

22 Common anaerobes included fusobacterium, bacteroides, porphyromonas, and prevotell

23 emonstrated greater abundance of Parvimonas, Fusobacterium, Campylobacter, Bacteroides, and Treponema

24 The prevalences of Fusobacterium, Campylobacter, Prevotella, Capnocytophaga

25 eriodontal pathogens belonging to the genera Fusobacterium, Cardiobacterium, Synergistes, and Selenom

26 ra including the Bacteroides fragilis group, Fusobacterium, Clostridium, and Peptostreptococcus.

27 ell Host & Microbe provide insights into the Fusobacterium-CRC relationship.

28 In decreasing order of prevalence, Fusobacterium, enteric rods, Prevotella intermedia/Prevo

29 We found that Fusobacterium (F.) nucleatum was abundant in colorectal

30 ytophaga, Cytophaga, Dialister, Eubacterium, Fusobacterium, Gemella, Mogibacterium, Peptostreptococcu

31 is absent in the nonoral species, including Fusobacterium gonidiaformans, Fusobacterium mortiferum,

32 fied an abundance of bacteria from the genus Fusobacterium in appendixes from patients with AA.

33 ent studies have implicated overabundance of Fusobacterium in association with colorectal adenomas an

34 ults support a link between the abundance of Fusobacterium in colonic mucosa and adenomas and suggest

35 nt studies have reported a high abundance of Fusobacterium in CRC subjects compared to normal subject

36 Most notably, the relative abundance of Fusobacterium increased whereas Streptococcus decreased

37 In situ hybridization analysis revealed that Fusobacterium is predominantly associated with cancer ce

38 ft with the antibiotic metronidazole reduced Fusobacterium load, cancer cell proliferation, and overa

39 from the oral cavity and stomach, including Fusobacterium, Megasphaera, Campylobacter, Capnocytophag

40 The Fusobacterium mortiferum malH gene, encoding 6-phospho-a

41 tibody to maltose 6-phosphate hydrolase from Fusobacterium mortiferum, and the two proteins exhibit a

42 ies, including Fusobacterium gonidiaformans, Fusobacterium mortiferum, Fusobacterium naviforme, Fusob

43 ibody against phospho-alpha-glucosidase from Fusobacterium mortiferum.

44 osidase, EC 3.2.1.86) has been purified from Fusobacterium mortiferum.

45 um gonidiaformans, Fusobacterium mortiferum, Fusobacterium naviforme, Fusobacterium russii, and Fusob

46 uggest that in patients aged 15 to 30 years, Fusobacterium necrophorum causes at least 10% of cases o

47 young adults (persons aged 15 to 24 years), Fusobacterium necrophorum causes endemic pharyngitis at

48 After Fusobacterium necrophorum grew in blood cultures, anaero

49 Fusobacterium necrophorum is a gram-negative, rod-shaped

50 Fusobacterium necrophorum was detected in 20.5% of patie

51 a patient with Lemierre's syndrome caused by Fusobacterium necrophorum who developed a right frontal

52 The most commonly implicated pathogen is Fusobacterium necrophorum, a gram-negative anaerobe that

53 Fusobacterium necrophorum, a gram-negative, rod-shaped,

54 Fusobacterium necrophorum, an obligate anaerobic bacteri

55 Fusobacterium necrophorum-positive pharyngitis occurs mo

56 sociated bacteria, Dichelobacter nodosus and Fusobacterium necrophorum.

57 For Fusobacterium nucleatum (100%/100%), there was no differ

58 7.4%), Porphyromonas gingivalis (15.1%), and Fusobacterium nucleatum (14.2%).

59 Further specificity was seen when Fusobacterium nucleatum (a middle colonizer), Aggregatib

60 Effects of Fusobacterium nucleatum (F. nucleatum) biofilm on epithe

61 pic dento-epithelial (OD-E) model exposed to Fusobacterium nucleatum (Fn) biofilm.

62 Fusobacterium nucleatum (Fn) has been associated with co

63 Fusobacterium nucleatum (Fn) is one of the most frequent

64 ction was used for detecting and quantifying Fusobacterium nucleatum (Fn), Aggregatibacter actinomyce

65 ermedia (Pi), Tannerella forsythia (Tf), and Fusobacterium nucleatum (Fn).

66 factor in coaggregated mixed infection with Fusobacterium nucleatum (Fn).

67 ivalis (Pg), Eubacterium saburreum (Es), and Fusobacterium nucleatum (Fn).

68 (Sg)/S. oralis (So)/S. sanguinis (Ss) and Sg/Fusobacterium nucleatum (Fn)/Porphyromonas gingivalis (P

69 l as with Veillonella sp. (early colonizer), Fusobacterium nucleatum (middle colonizer), and Aggregat

70 Endothelial cells were infected with Fusobacterium nucleatum (strain 25586) for periods of 4,

71 alis (Pg); 4) group G-PgFn: oral gavage with Fusobacterium nucleatum + Pg; 5) group I-Pg: heat-killed

72 monas gingivalis, Prevotella intermedia, and Fusobacterium nucleatum activated both TLRs, but TLR4 pl

73 eration sequencing implicated coinfection of Fusobacterium nucleatum and Actinomyces israelii, resolv

74 also significantly associated with pathogens Fusobacterium nucleatum and Aggregatibacter actinomycete

75 mixed infection with the periodontopathogens Fusobacterium nucleatum and Porphyromonas gingivalis.

76 The most frequently found bacteria were Fusobacterium nucleatum and Prevotella denticola.

77 Fusobacterium nucleatum appears to play a role in colore

78 Candida albicans and Fusobacterium nucleatum are well-studied oral commensal

79 these findings by identifying the bacterium Fusobacterium nucleatum as a previously unrecognized che

80 gregatibacter actinomycetemcomitans JP2, and Fusobacterium nucleatum ATCC 10953 were unable to grow a

81 s biofilm (Streptococcus sanguinis DSM20068, Fusobacterium nucleatum ATCC10953, and Porphyromonas gin

82 Attachment of Fusobacterium nucleatum ATCC25586 and Prevotella interme

83 h extraction followed by oral infection with Fusobacterium nucleatum caused BONJ-like lesions and del

84 vivo experiments, the combination of Pam and Fusobacterium nucleatum caused the death of gingival fib

85 ous studies showed that hBD-2 was induced by Fusobacterium nucleatum cell wall extract without the in

86 Gnotobiotic studies revealed that while Fusobacterium nucleatum clinical isolates with FadA and

87 Obligate anaerobes other than Fusobacterium nucleatum coaggregated only poorly with ox

88 for the presence and amount of EBV, CMV, and Fusobacterium nucleatum DNA using real-time polymerase c

89 F together with either Escherichia coli DNA, Fusobacterium nucleatum DNA, or Porphyromonas gingivalis

90 eviously demonstrated that sonic extracts of Fusobacterium nucleatum FDC 364 were capable of inhibiti

91 employed by the Gram-negative oral pathogen Fusobacterium nucleatum for cell death induction of huma

92 s were significantly higher for P. micra and Fusobacterium nucleatum for the screw-retained group.

93 In previous studies Fusobacterium nucleatum has been shown to induce either

94 report a case of Lemierre's syndrome due to Fusobacterium nucleatum in a previously healthy 19-year-

95 infection with Porphyromonas gingivalis and Fusobacterium nucleatum in mice.

96 inoculation of Porphyromonas gingivalis and Fusobacterium nucleatum in young (4 to 5 mo) and aged (1

97 /+) mouse model of intestinal tumorigenesis, Fusobacterium nucleatum increases tumor multiplicity and

98 ed replication plan of key experiments from 'Fusobacterium nucleatum infection is prevalent in human

99 thelial cells reached its peak 2 h following Fusobacterium nucleatum infection whereas it rapidly dec

100 Fusobacterium nucleatum is a common oral anaerobe involv

101 Fusobacterium nucleatum is a Gram-negative anaerobe asso

102 Fusobacterium nucleatum is a gram-negative anaerobe that

103 Fusobacterium nucleatum is a gram-negative anaerobe ubiq

104 Fusobacterium nucleatum is a Gram-negative oral anaerobe

105 Fusobacterium nucleatum is a gram-negative oral anaerobe

106 Fusobacterium nucleatum is among the most prevalent bact

107 Fusobacterium nucleatum is an oral pathogen that is link

108 Fusobacterium nucleatum is associated with colorectal ca

109 Fusobacterium nucleatum is capable of binding to and inv

110 ristic of the suspected periodontal pathogen Fusobacterium nucleatum is its ability to adhere to a pl

111 agonize TLR4-specific activation by agonist, Fusobacterium nucleatum LPS.

112 Fusobacterium nucleatum might be the cause or consequenc

113 ly significant, Porphyromonas gingivalis and Fusobacterium nucleatum occur in higher concentrations m

114 thogens such as Porphyromonas gingivalis and Fusobacterium nucleatum produce five different short-cha

115 ere we present the crystal structures of the Fusobacterium nucleatum riboswitch bound to FMN, ribofla

116 Chemical mapping on the Fusobacterium nucleatum riboswitch with N-methylisatoic

117 e draft genome sequence and its analysis for Fusobacterium nucleatum sub spp. vincentii (FNV), and co

118 Fusobacterium nucleatum subsp. polymorphum was the most

119 rometry (MALDI-TOF MS) for identification of Fusobacterium nucleatum subspecies.

120 eponema denticola, Tannerella forsythia, and Fusobacterium nucleatum to colonize the periodontium and

121 givalis, whereas phagocytosis of heat-killed Fusobacterium nucleatum was augmented compared with that

122 Fusobacterium nucleatum was present in 17 patients prior

123 omonas gingivalis, Tannerella forsythia, and Fusobacterium nucleatum were analyzed for prediction of

124 , Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum were assessed in anaerobic condi

125 Three native plasmids of Fusobacterium nucleatum were characterized, including DN

126 votella intermedia, Eikenella corrodens, and Fusobacterium nucleatum were determined by real-time pol

127 treptococcus mitis, Veillonella parvula, and Fusobacterium nucleatum) and the same biofilm plus the p

128 i, Actinobacillus actinomycetemcomitans, and Fusobacterium nucleatum) biofilm formation under anaerob

129 inations that resulted in tailing endpoints (Fusobacterium nucleatum, 86% agreement) or in cases of l

130 production of CCL20 and hBDs in response to Fusobacterium nucleatum, a commensal bacterium of the or

131 Using Fusobacterium nucleatum, a Gram-negative anaerobe freque

132 entified a cell wall-associated protein from Fusobacterium nucleatum, a Gram-negative bacterium of th

133 t evidence for the immunosuppressive role of Fusobacterium nucleatum, a gram-negative oral bacterium

134 We previously reported that Fusobacterium nucleatum, a ubiquitous gram-negative bact

135 Key quorum-sensing plaque bacteria, such as Fusobacterium nucleatum, act as bridging species between

136 helial cell response to the common bacterium Fusobacterium nucleatum, an important bridging species t

137 It can be coisolated with Fusobacterium nucleatum, an opportunistic bacterial path

138 Fusobacterium nucleatum, an opportunistic pathogen, is t

139 D-2 mRNA was induced by cell wall extract of Fusobacterium nucleatum, an oral commensal microorganism

140 ophilus aphrophilus, Actinomyces naeslundii, Fusobacterium nucleatum, and A. actinomycetemcomitans, a

141 as Prevotella intermedia, Selenomonas noxia, Fusobacterium nucleatum, and Actinobacillus actinomycete

142 hyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, and Aggregatibacter actinomycet

143 lls stimulated with a periodontal bacterium, Fusobacterium nucleatum, and other stimulants.

144 inae, Mobiluncus mulieris, Prevotella bivia, Fusobacterium nucleatum, and Peptoniphilus species.

145 tella intermedia, Streptococcus intermedius, Fusobacterium nucleatum, and Peptostreptococcus micros,

146 ates were Prevotella sp., Porphyromonas sp., Fusobacterium nucleatum, and Peptostreptococcus sp.

147 Of those, Bergeyella, Fusobacterium nucleatum, and Sneathia sanguinegens had n

148 Aggregatibacter aphrophilus, Fusobacterium nucleatum, and Streptococcus intermedius o

149 gar Candida medium, coaggregation assay with Fusobacterium nucleatum, and sugar assimilation profiles

150 hyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, and Tannerella forsythia.

151 Bacteria, such as Fusobacterium nucleatum, are present in the tumor microe

152 cus anginosus, Porphyromonas gingivalis, and Fusobacterium nucleatum, as well as Campylobacter rectus

153 hyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Campylobacter rectus, and Trepo

154 hyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Campylobacter rectus, Eikenella

155 omonas gingivalis, Campylobacter rectus, and Fusobacterium nucleatum, could cause localized bone reso

156 Fusobacterium nucleatum, Eikenella corrodens, Actinobaci

157 s as potentiators of tumorigenesis-including Fusobacterium nucleatum, enterotoxigenic Bacteroides fra

158 wall extracts of Porphyromonas gingivalis or Fusobacterium nucleatum, Escherichia coli lipopolysaccha

159 monas gingivalis, Prevotella intermedia, and Fusobacterium nucleatum, have recently been shown to sec

160 dentify an anaerobic Gram-negative bacillus, Fusobacterium nucleatum, in a patient with "culture-nega

161 otella intermedia, Campylobacter rectus, and Fusobacterium nucleatum, in subgingival dental plaque of

162 and difficult-to-cultivate species, such as Fusobacterium nucleatum, Leptotrichia (Sneathia) spp., a

163 ella forsythia [previously T. forsythensis], Fusobacterium nucleatum, Parvimonas micra [previously Pe

164 pathogens, including Prevotella intermedia, Fusobacterium nucleatum, Peptostreptococcus micros, and

165 ection protocol using Prevotella intermedia, Fusobacterium nucleatum, Peptostreptococcus micros, and

166 their ability to coaggregate with strains of Fusobacterium nucleatum, Peptostreptococcus micros, Pept

167 , Campylobacter curvus, Eikenella corrodens, Fusobacterium nucleatum, Porphyromonas gingivalis, and P

168 nisms (Actinobacillus actinomycetemcomitans, Fusobacterium nucleatum, Porphyromonas gingivalis, Pepto

169 ctinomycetemcomitans), Campylobacter rectus, Fusobacterium nucleatum, Porphyromonas gingivalis, Prevo

170 ntified virulence mechanisms of oral species Fusobacterium nucleatum, Porphyromonas gingivalis, Strep

171 imens yielded pathogenic bacteria, including Fusobacterium nucleatum, Prevotella heparinolytica, Prev

172 three orange-complex periodontal pathogens (Fusobacterium nucleatum, Prevotella intermedia, and Camp

173 phyromonas gingivalis, Tannerella forsythia, Fusobacterium nucleatum, Prevotella intermedia, and Camp

174 phyromonas gingivalis, Tannerella forsythia, Fusobacterium nucleatum, Prevotella intermedia, and tota

175 same double-labeling techniques to identify Fusobacterium nucleatum, Prevotella intermedia, oral Cam

176 anaerobic pathogens, Prevotella intermedia, Fusobacterium nucleatum, Streptococcus intermedius, and

177 nfections (endodontic pathogens [EP]), i.e., Fusobacterium nucleatum, Streptococcus intermedius, Parv

178 e in corncob formation between S. crista and Fusobacterium nucleatum, this property was examined.

179 ms enumerated were Porphyromonas gingivalis, Fusobacterium nucleatum, Veillonella sp., and total anae

180 lla, Salmonella, Haemophilus influenzae, and Fusobacterium nucleatum, which share structural and func

181 activation by another periodontal bacterium, Fusobacterium nucleatum.

182 bserved for Bacteroides thetaiotaomicron and Fusobacterium nucleatum.

183 llowing stimulation of epithelial cells with Fusobacterium nucleatum.

184 Actinomyces israelii with the coisolation of Fusobacterium nucleatum.

185 adA adhesin from the Gram-negative bacterium Fusobacterium nucleatum.

186 olymicrobial oral infections with or without Fusobacterium nucleatum.

187 cus gordonii and the opportunistic commensal Fusobacterium nucleatum.

188 symporter (NSS) family has been cloned from Fusobacterium nucleatum.

189 olic analysis of the dominant oral bacterium Fusobacterium nucleatum.

190 ggregation with the anaerobic oral bacterium Fusobacterium nucleatum.

191 mediated adherence to a peridontal pathogen, Fusobacterium nucleatum.

192 ella parvula, Peptostreptococcus micros, and Fusobacterium nucleatum.

193 , Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum.

194 xed infection with the otherwise stimulatory Fusobacterium nucleatum.

195 inomycetemcomitans, Eikenella corrodens, and Fusobacterium nucleatum/periodonticum were statistically

196 ecrophorum, and F. varium are the species of Fusobacterium observed in AA samples.

197 The mean log abundance of Fusobacterium or cytokine gene expression between cases

198 It is highly conserved among F. nucleatum, Fusobacterium periodonticum, and Fusobacterium simiae, t

199 CC 25586, gene FN1704) that we hereby rename Fusobacterium phospholipase autotransporter (FplA).

200 identified from the 39 defects, belonging to Fusobacterium, Pseudomonas, Streptococcus, Filifactor, a

201 cterium mortiferum, Fusobacterium naviforme, Fusobacterium russii, and Fusobacterium ulcerans.

202 Fusobacterium sequences were enriched in carcinomas, con

203 nucleatum, Fusobacterium periodonticum, and Fusobacterium simiae, the three most closely related ora

204 vimonas micra, Peptostreptococcus sp. OT113, Fusobacterium sp. OT203, Pseudoramibacter alactolyticus,

205 E. corrodens, P. micros, Capnocytophaga and Fusobacterium sp., enteric Gram-negative rods, Enterococ

206 inomycetemcomitans (1.1% of total isolates), FusobActerium species (7.9%), Campylobacter species (2.2

207 eroPack system was most efficient in growing Fusobacterium species (P = 0.0001).

208 monas gingivalis, Bacteroides forsythus, and Fusobacterium species as well as beta-hemolytic streptoc

209 ects had a significantly higher abundance of Fusobacterium species compared to controls (p = 0.01).

210 We assessed the abundance of Fusobacterium species in the normal rectal mucosa of sub

211 Eubacterium species, Campylobacter species, Fusobacterium species, and Peptostreptococcus micros.

212 Furthermore, due to its uniqueness to oral Fusobacterium species, fadA may be used as a marker to d

213 thogens, including Porphyromonas gingivalis, Fusobacterium species, Peptostreptococcus micros, Bacter

214 ly encountered anaerobes were Prevotella and Fusobacterium species.

215 72 isolates), Prevotella spp. (71 isolates), Fusobacterium spp. (21 isolates), Porphyromonas spp. (20

216 Metagenomic analyses indicate that symbiotic Fusobacterium spp. are associated with human colorectal

217 We find that Fusobacterium spp. are enriched in human colonic adenoma

218 ., Cardiobacterium sp., Eikenella corrodens, Fusobacterium spp., Gemella haemoylsans, and Neisseria s

219 e pathogens of noma, such as spirochetes and Fusobacterium spp., were detected in at least one subjec

220 Biochemical analysis of multiple Fusobacterium strains revealed that FplA is expressed as

221 represented 19 novel species of Prevotella, Fusobacterium, Streptococcus, Actinomyces, Capnocytophag

222 m that in humans, with some bacteria such as Fusobacterium switching roles between the two species (a

223 cterium naviforme, Fusobacterium russii, and Fusobacterium ulcerans.

224 hort and found that the overall abundance of Fusobacterium was 415 times greater in CRC versus adjace

225 ses, the correlation for local TNF-alpha and Fusobacterium was r = 0.33, p = 0.06 while it was 0.44,

226 est tertile, subjects with high abundance of Fusobacterium were significantly more likely to have ade