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1        5-HT1P agonists specifically activate G alpha o, the immunoreactivity of which was found to be
2  Moody, the G protein subunits G alpha i and G alpha o, and the regulator of G protein signaling Loco
3 on sequence within G alpha s, G alpha i, and G alpha o showed no immunoreactivity to the complex or i
4 lpha-subunits (G alpha q/11, G alpha i1, and G alpha o) were not different in depressed suicide and c
5 ists was partially blocked by G alpha i2 and G alpha o antibodies and additively blocked by a combina
6 cted in immunoprecipitates of G alpha i3 and G alpha o antisera but not with antibodies for other G a
7 precipitation of A1-AdoR with G alpha i3 and G alpha o proteins by 287% and 245%, respectively, in 6-
8 precipitation of A1-AdoR with G alpha i3 and G alpha o proteins decreased by 22% and 21%, respectivel
9 ific antisera directed against G alpha q and G alpha o but not G alpha s and G alpha i precipitated s
10 imulated the palmitoylation of G alpha q and G alpha o, and this response was blocked by the alpha 1-
11 a i1, G alpha i2, G alpha i3, G alpha z, and G alpha o, but not with members of other G alpha subfami
12   Individually, anti-G alpha i1/2/3 and anti-G alpha o only partially inhibited the action of NE on K
13 , anti-G beta, anti-G alpha i1/2/3, and anti-G alpha o) were used.
14 ction, but not by anti-G alpha i3 or by anti-G alpha o/G alpha i3 antibody injection, suggesting that
15 ntracellular injection of GDP beta S or anti-G alpha o Fab fragments but were potentiated and prolong
16 eurons; furthermore, it is expressed by both G alpha o+ and G alpha i2+ subsets.
17   Immunohistochemical studies show that both G alpha o and G alpha i2 are enriched in VNO microvilli,
18 nse to 5-HT involves activation of PC-PLC by G alpha o to liberate diacylglycerol, which stimulates P
19 ulates pumping through a mechanism involving G alpha o and G alpha q.
20                                    Moreover, G alpha o and G alpha i2 are highly expressed by separat
21 sequences from other palmitoylated proteins (G alpha o and GAP43) revealed that the presence of palmi
22 th G alpha q, alpha 1b-AR was also linked to G alpha o.
23  VNO, we found that mRNAs encoding only two, G alpha o and G alpha i2, are highly expressed in VNO ne

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