ライフサイエンスコーパス: G-gamma

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1 G gamma(13) contains a C-terminal asparagine-proline-try

2 G gamma(13) is a divergent member of the G gamma subunit

3 G gamma(13) was observed to associate with all five G be

4 th different G beta subunits, only G beta(1)/G gamma(13), G beta(3)/G gamma(13), and G beta(4)/G gamm

5 units, only G beta(1)/G gamma(13), G beta(3)/G gamma(13), and G beta(4)/G gamma(13) pairings were fou

6 ma(13), G beta(3)/G gamma(13), and G beta(4)/G gamma(13) pairings were found to form stable dimers de

7 tein signaling (RGS) proteins that contain a G gamma-like (GGL) domain.

8 ansfected with D1A receptor and G beta 1 and G gamma 2 cDNAs.

9 cting either tagged or untagged G beta 1 and G gamma 2 with excess G alpha(oA) cDNA.

10 alpha subunits but only a single G beta and G gamma subunit suggesting that the specific response to

11 yeast STE4 and STE18 genes encode G beta and G gamma subunits, respectively, that the G betagamma com

12 Using Ras- and G gamma-specific peptide substrates and competition assa

13 d by immunohistochemical staining using anti-G gamma c antibodies.

14 Multiple G beta/G gamma(13) pairings were also functional in cellular as

15 uence identity with the corresponding bovine G gamma c isoform (85%) and human rod G gamma 1 (63%).

16 ina, these results imply that this divergent G gamma subunit can act in signal transduction pathways

17 Human G gamma c subunit shares a high degree of sequence ident

18 We report here the characterization of human G gamma c and its gene structure.

19 the two factors (beta thalassaemia and Xmn I-G gamma site) on chromosome 11p, there is a third major

20 n gamma subunit (G gamma c, previously named G gamma b), which may play a key role in coupling the co

21 We propose that GpgA is the only A. nidulans G gamma-subunit and is required for normal vegetative gr

22 s (labeled by antibodies against G alpha(o), G gamma 13, or mGluR6).

23 Coupled with our detection of G gamma(13) mRNA in mouse and human brain and retina, th

24 However, upon cellular co-expression of G gamma(13) with different G beta subunits, only G beta(

25 udy, we investigated the functional range of G gamma(13) assembly with G beta subunits using multiple

26 terol enrichment did not alter expression of G-gamma-5 mRNA, as assessed by reverse transcriptase pol

27 ght, contains three G alpha, one G beta, one G gamma subunits and phosducin-like protein BDM-1 that h

28 GFP mutants to the N-terminus of G beta 1 or G gamma 2 does not qualitatively impair their ability to

29 adA (G alpha), SfaD (G beta), and a presumed G gamma.

30 native structure without its partner protein G gamma.

31 (NPW) tripeptide, a hallmark of RGS protein G gamma-like (GGL) domains which dimerize exclusively wi

32 a single gene named gpgA encoding a putative G gamma-subunit.

33 bovine G gamma c isoform (85%) and human rod G gamma 1 (63%).

34 tron splice sites similar to that of the rod G gamma 1 gene (GNGT1).

35 nas a cone-specific G-protein gamma subunit (G gamma c, previously named G gamma b), which may play a

36 Collectively, these data indicate that G gamma(13) forms functional G beta gamma dimers with a

37 In both cases, the G gamma subunit is ineffective by itself, but overexpres

38 Nucleotide sequence analysis of the G gamma c gene (GNGT2) reveals a structure consisting of

39 The elucidation of the G gamma c gene structure would facilitate the identifica

40 G gamma(13) is a divergent member of the G gamma subunit family considered to be a component of t

41 amma-globin genes, 5' flanking region of the G gamma-globin gene, and A gamma-globin gene IVS-II.

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