ライフサイエンスコーパス: GABA-gated

1 ients required for the inhibitory effects of GABA-gated and serotonin-gated chloride channels on C. e

2 Blocking glycine- and GABA-gated anion currents had opposing effects on sponta

3 e expression of bovine beta1 subunits formed GABA-gated C1- channels.

4 ropic receptor subunits (LCCH3 and GRD) form GABA-gated cation channels when heterologously expressed

5 tes than in the synaptic terminals, and that GABA-gated channels in the dendrites may generate a hype

6 Cl(-) gradient such that Cl(-) flow through GABA-gated channels is reversed and excites rather than

7 Studies of acetylcholine-, glutamate- and GABA-gated channels using rapid agonist application now

8 e an inhibitory chloride conductance through GABA-gated channels, and thereby achieve their sedative-

9 The inhibition of gamma-aminobutyric acid (GABA)-gated chloride currents by the protein kinase C (P

10 A GABA-gated chloride channel subunit from Drosophila mela

11 subunit GluCl alpha (DmGluCl alpha) and the GABA-gated chloride channel subunit Rdl (DmRdl) proteins

12 Resistance to Dieldrin gene, Rdl, encodes a GABA-gated chloride channel subunit that is targeted by

13 ting and readily detoxified modulator of the GABA-gated chloride channel.

14 convulsants and insecticides that block the GABA-gated chloride channel.

15 GABA-gated chloride channels (GABAARs) trafficking is in

16 AR) types C (GABACR) and A (GABAAR) are both GABA-gated chloride channels that are distinguished by t

17 Rho(1) receptor-channels (rho(1)Rs) are GABA-gated chloride channels that exhibit slow kinetics,

18 Chloride influx through GABA-gated chloride channels, the primary mechanism by w

19 uch as voltage-dependent sodium channels and GABA-gated chloride channels.

20 erved here, however, was inconsistent with a GABA-gated chloride conductance mechanism.

21 These results suggest that PS inhibits GABA-gated chloride currents by enhancing receptor desen

22 here is an increase in the peak amplitude of GABA-gated chloride currents compared with wild-type rec

23 Additionally, GABA-gated chloride currents in HEK 293 cells expressing

24 urons, the dileucine motif peptide increases GABA-gated chloride currents of native GABA(A) receptors

25 lls, an effect accompanied by an increase in GABA-gated chloride currents.

26 tudies of presynaptic inhibition mediated by GABA-gated Cl channels and then focus on presynaptic nic

27 nflux of Cl(-) probably occurred through the GABA-gated Cl(-) channel because the effects of H(2)O(2)

28 l's receptive field, while synaptic terminal GABA-gated Cl(-) channels generate the hyperpolarization

29 This would allow dendritic GABA-gated Cl(-) channels to generate the depolarization

30 ral basis of anion selectivity of Drosophila GABA-gated Cl(-) channels, the permeation properties of

31 Chloride influx through GABA-gated Cl(-) channels, the principal mechanism for i

32 In contrast, picrotoxin, which blocks the GABA-gated Cl- channel, did not inhibit the secondary ri

33 dominantly in the retina and forms homomeric GABA-gated Cl- channels that are clearly different from

34 the benzodiazepine (BDZ) lorazepam (LZM) on GABA-gated Cl- current, assessed using whole cell patch

35 ated by reduced diazepam potentiation of the GABA-gated current and GABA potentiation of [3H]flunitra

36 Under control conditions, GABA-gated current deactivated biexponentially, with tau

37 nversely correlated with BDZ potentiation of GABA-gated current, assessed using whole cell patch clam

38 GABA-gated currents (I(GABA)) were measured before and a

39 Isoflurane enhanced GABA-gated currents at anesthetic concentrations but the

40 e with only minimal effects of isoflurane on GABA-gated currents at concentrations associated with lo

41 Inhibition of GABA-gated currents by furosemide, a selective inhibitor

42 In contrast, ethanol had no effect on GABA-gated currents even at lethal concentrations, i.e.

43 s for the effects of isoflurane on NMDA- and GABA-gated currents has revealed both EC50 and Hill slop

44 THDOC (100 nM) significantly potentiated GABA-gated currents in cells transfected with combinatio

45 We report here that NO analogs reduce GABA-gated currents in cultured retinal amacrine cells v

46 d enhanced sensitivity to AP potentiation of GABA-gated currents in DGGCs, but not in CA1 pyramidal c

47 pregnan-20-1 (THDOC)-induced potentiation of GABA-gated currents in transfected HEK 293 cells and in

48 In contrast, GABA-gated currents of the NTS were inhibited by the div

49 THDOC potentiation of GABA-gated currents was greater in cerebellar granule ce

50 significant difference in La3+ modulation of GABA-gated currents was observed between alpha1beta3gamm

51 EC50 and Hill slope for the potentiation of GABA-gated currents were significantly greater than thos

52 which 1-3 mM alcohol preferentially enhanced GABA-gated currents, and low doses of alcohol attenuated

53 e extent of furosemide-induced inhibition of GABA-gated currents.

54 ults indicate that La3+ has a dual action on GABA-gated currents: it decreases desensitization and in

55 eta subunits have been reported to be either GABA-gated or capable of forming anion-selective channel