ライフサイエンスコーパス: GC-rich region

1 KLF5's promoter lacks a TATA box and has a GC-rich region.

2 ificantly from the mechanism mediated by the GC-rich region.

3 between positions +52 and +93 base pairs, a GC-rich region.

4 smid pBR322, which contains an AT-rich and a GC-rich region.

5 tential Sp1 binding sites within this highly GC-rich region.

6 box and has several GC boxes within a highly GC-rich region.

7 g more methyl induced CpG-->TpG mutations in GC rich regions.

8 tate replication through telomeres and other GC-rich regions.

9 ing four hypoxia-response elements and three GC-rich regions.

10 gion lacks canonical TATA and CAAT boxes and GC-rich regions.

11 lysis of the VEGF gene promoter identified a GC-rich region (-66 to -47) which was required for E2-in

12 tream of exon 1 consists of a promoter-like, GC-rich region and a number of putative cis active eleme

13 '-upstream region was sequenced, revealing a GC-rich region and TATA-less sequence containing several

14 ve significant enrichment of heritability in GC-rich regions and in higher-frequency SNPs for both sc

15 The SEGS are characterized by GC-rich regions and the absence of long open reading fra

16 man PGHS-1 gene lacks a TATA box, has a very GC-rich region, and contains multiple transcription star

17 consensus element around -45 bp and several GC-rich regions around -60, each of which is responsible

18 s stretch of 78 base pairs, which contains a GC-rich region as well as the TATA box.

19 ion site and another laboratory identified a GC-rich region between the TATA box and transcription in

20 thod not only for amplification of extremely GC-rich regions, but also for routine DNA diagnostics an

21 This contained a GC-rich region composed of two tandemly arrayed Sp-1 sit

22 egion between -62 and -55, which contained a GC-rich region consistent with a consensus sequence for

23 This region contains no TATA box but has GC-rich regions, consistent with the ubiquitous expressi

24 This GC-rich region constitutes a "GC box" capable both of bi

25 ed the essential promoter region to a highly GC-rich region containing four Sp-1 binding sites.

26 ses of the VEGF promoter demonstrated that a GC-rich region containing four Sp1 response elements, lo

27 f the 2.2 kb TF 5' promoter indicated that a GC-rich region containing three copies each of the EGR-1

28 A guanine- and cytosine-rich (GC-rich) region directly upstream of the P1 site has bee

29 Furthermore, disruption of the GC-rich region dramatically decreases transcription fact

30 The nuclear factors Sp1 and Sp3 bound this GC-rich region in N2A, H19-7, and HRP.1 cells.

31 EKLF site within a previously characterized GC-rich region in the p21 proximal promoter but also by

32 family of transcription factors that bind to GC-rich regions in gene promoters.

33 thermophilic organisms: simply screening for GC-rich regions in the AT-rich Methanococcus jannaschii

34 on of this promoter is mediated equally by a GC-rich region located between bp -303 and -271 and by t

35 ugments promoter activity of p21 through the GC-rich region located between nucleotides -84 and -74 w

36 of the p21(WAF1/CIP1) promoter showed that a GC-rich region located between positions -83 and -74, wh

37 CpG islands are GC-rich regions located in the promoter regions of house

38 lated promoter activity occurred through two GC-rich regions located within 633 bp of the transcripti

39 urther point mutation studies found that two GC-rich region mutations disrupted the Satb2 130bp promo

40 The HSK2 promoter contains a GC-rich region, not present in the mouse promoter, and h

41 A relatively GC- rich region of the genome 5' of the alternatives to

42 re CCAAT(N9)CCACG, with N being a strikingly GC-rich region of 9 bp.

43 ags with 100% heavy nucleosides to examine a GC-rich region of a polycytidine string with an unknown

44 howed that WP631 binds preferentially to the GC-rich region of the DNA.

45 A relatively GC-rich region of the genome 5' of exon 1 was distinctly

46 A relatively GC-rich region of the genome just 5' of exon 1 as well a

47 These mutations, clustered around the GC-rich region of the human MnSOD promoter, change the b

48 Sp1-p300 DNA binding complex on the proximal GC-rich region of the survivin promoter.

49 proteins from ZR-75 cells with the proximal GC-rich region of the VEGF gene promoter were investigat

50 e with worker-biased expression are found in GC-rich regions of the bee genome and also experience hi

51 selective manner, methylation alterations at GC-rich regions of the genome in metachronous tumors and

52 ions for the accumulation of Alu elements in GC-rich regions of the human genome.

53 CpG islands are GC-rich regions often located in the 5' end of genes and

54 effects are mediated by interaction with the GC-rich region on the promoter.

55 he promoter of the rat pgp2/mdr1b gene has a GC-rich region (pgp2GC) that is highly conserved in mdr

56 iments demonstrate that the proximal, highly GC-rich region (positions -165 to -139) of the human PDG

57 The binding of EGR1 to the GC-rich region prevented TBP binding to the AT-rich regi

58 moter and that targeted deletion of a single GC-rich region spanning -93 to -58 interrupts Sp1- and D

59 nsity of Alu is two to three times higher in GC-rich regions than in AT-rich regions, while the oppos

60 taining a half-estrogen response element and GC-rich region that interact with ER and Sp1 proteins.

61 These genes tended to cluster in GC-rich regions that have poor coverage in genome sequen

62 onal point mutants were used to identify two GC-rich regions that were responsible for VEGF promoter

63 vealed no classical TATA or CCAAT box in the GC-rich region upstream of cap site.

64 We localized promoter activity to a 452-bp GC-rich region upstream of noncoding exon A, including a

65 A highly GC-rich region upstream of the P1 promoter plays an impo

66 The human bcl-2 gene contains a GC-rich region upstream of the P1 promoter that has been

67 The human BCL-2 gene contains a 39-bp GC-rich region upstream of the P1 promoter that has been

68 nd to lack TATA or CAAT boxes and to contain GC-rich regions, which are features typical of promoters

69 particular: structural variants, variants in GC-rich regions, which have significantly improved cover

70 ellifera, represents a mosaic of GC-poor and GC-rich regions with rates of recombination an order of

71 nitiation sites in brain and thymus within a GC-rich region, with multiple Sp1-binding motifs located