ライフサイエンスコーパス: GC-rich sequence

1 ers of Abflp- and Rap1p-binding sites, and a GC-rich sequence.

2 nts showed that PAGE4 preferentially binds a GC-rich sequence.

3 sting of two LANA binding sites (LBSs) and a GC-rich sequence.

4 could activate the NF2 promoter through the GC-rich sequence.

5 ed that it lacks the TATA box but contains a GC-rich sequence.

6 acent to each other and separated by a 16-bp GC-rich sequence.

7 lex, in the order of AT-rich > random > or = GC-rich sequence.

8 Sp1 bound only to the -18 GC-rich sequence.

9 T-rich sequences suffer greater loss than do GC-rich sequences.

10 collagen promoter through its binding to two GC-rich sequences.

11 reference of 3 toward AT-rich sequences over GC-rich sequences.

12 promote recombination more efficiently than GC-rich sequences.

13 binding transcription inhibitor specific for GC-rich sequences.

14 EAMP), to isolate tumour-specific methylated GC-rich sequences.

15 a typical TATA-less promoter containing many GC-rich sequences.

16 id of either alternating A and T residues or GC-rich sequences.

17 substitution error frequencies in AT- versus GC-rich sequences.

18 proteins whose zinc finger motifs also bind GC-rich sequences.

19 o the A form of DNA containing predominately GC-rich sequences.

20 gous C-terminal zinc finger motifs that bind GC-rich sequences.

21 der to enhance DNA polymerase extension over GC-rich sequences.

22 sented to explain recombination silencing by GC-rich sequences.

23 in multiple exons with highly repetitive and GC-rich sequences.

24 Despite the gene's repetitive and GC-rich sequences, 13% of RPGR gene copies showed mutati

25 ny sequence-specific role, we randomized the GC-rich sequence ((-20)CCGGCTCG(-13)) within the spacer

26 By contrast, GC-rich sequences (60% GC) are found to undergo a revers

27 posase exhibits a target site preference for GC rich sequences and hairpin structures.

28 multiple transcriptional start sites (TSS), GC-rich sequences and a promoter located within -205/+63

29 y upstream of the coding region and contains GC-rich sequences and a typical TATA box whereas the oth

30 acteristic of a housekeeping gene, including GC-rich sequences and absence of a functional TATA eleme

31 RGG box of ICP27 are required for binding to GC-rich sequences and that the N-terminal portion of ICP

32 This suggests that such GC-rich sequences are difficult to sequence and therefor

33 Mutation of a GC-rich sequence at -172 relative to the translational s

34 noglobulin and HIV promoters to identify the GC-rich sequences at each end required for Sp-factor tar

35 The presence of GC-rich sequences at the 5' end of genes may influence t

36 The largest cluster involved GC-rich sequences at the 5' ends of introns that co-occu

37 the transcription factor YY1 embedded within GC-rich sequences between the two tandem CCAAT repeats p

38 nd GC-cluster C, an evolutionarily conserved GC-rich sequence block immediately downstream from the r

39 dies have indicated that Sp2 binds poorly to GC-rich sequences bound by Sp1 and Sp3, and further func

40 promoters have led to the identification of GC-rich sequences capable of binding to Sp1 transcriptio

41 analysis with the wild-type protein bound to GC-rich sequences did not show any discernible folding.

42 In addition, we have identified a GC-rich sequence downstream from the TATA box (the BURE)

43 on hot spots, we inserted 30-nucleotide-long GC-rich sequences downstream of AU-rich homologous recom

44 of protein binding included a region in the GC-rich sequences downstream of the 75-bp repeats (only

45 FI sites emerged with a general accretion of GC-rich sequences downstream of the eukaryotic transcrip

46 TA sequence, whereas Sp1 requires the distal GC-rich sequence elements to stimulate gene expression.

47 nergy calculations show that single-stranded GC-rich sequences exhibit more favorable solvation by ch

48 cts DNA and extends the footprint of CREB to GC-rich sequences flanking the core CRE-like element.

49 the promoter, both MAZ and Sp1 interact with GC-rich sequences flanking the TATA box.

50 at a primary target of MAZ activation is the GC-rich sequences flanking the TATA sequence, whereas Sp

51 rved C-terminal zinc finger motifs that bind GC-rich sequences found in promoters of numerous genes e

52 logous C(2)H(2) zinc finger motifs that bind GC-rich sequences found in the promoters of a large numb

53 th a VEGF promoter construct revealed that a GC-rich sequence from bp -194 to -50 of the VEGF promote

54 pG binding domain column isolates methylated GC-rich sequences from both tumours and surrounding norm

55 -gamma-induced gene revealed protection of a GC-rich sequence (GC box) with the same temporal pattern

56 derivative, DB1242, binds specifically to a GC-rich sequence, -GCTCG-.

57 ghly structured and nonstructured downstream GC-rich sequences had a similar "homologous recombinatio

58 51, the absence of TATA and CAAT patterns, a GC-rich sequence in the promoter region, and initiation

59 ditercalinium selectively recognizes certain GC-rich sequences in DNA and to identify some of the fac

60 Mutational analysis of the GC-rich sequences in the major late promoter suggested t

61 KLF10 occupied GC-rich sequences in the promoter region of the EMT-prom

62 BTEB1 bound to GC-rich sequences in the proximal TrbetaA promoter in vi

63 mily an overlapping sequence specificity for GC-rich sequences in the regulatory regions of multiple

64 In addition, upstream insertions of similar GC-rich sequences increased the incidence of homologous

65 e same AT-rich sequence is concatenated to a GC-rich sequence known to undergo a B-to-S transition ra

66 lized a minimal promoter activity to a 21-bp GC-rich sequence located 130 bp upstream of the X protei

67 the transactivation is partly mediated by a GC-rich sequence located in the promoter.

68 uces the translation of p21 via binding to a GC-rich sequence located within the 5' region of p21 mRN

69 g of the transcription factor Sp1 at the two GC-rich sequences located within the -340 to -249 region

70 The GC-rich sequence-mediated recombination silencing mapped

71 upstream stimulating factor 1 (USF-1) and a GC-rich sequence motif which can bind to Sp1 (proximal S

72 ) regulates gene transcription by binding to GC-rich sequence motifs present in the promoters of nume

73 al properties of cytosine also contribute to GC-rich sequences occurring in Z DNA with a higher frequ

74 subset of mammalian ERSEs, N(9) represents a GC-rich sequence of 9 bp that is conserved across specie

75 ed, in their 5' untranslated region (UTR), a GC-rich sequence of approx. 180 bases.

76 To study the effect of GC-rich sequences on the recombination hot spots, we ins

77 ated by comparing the IS6110 and polymorphic GC-rich sequence patterns of M. tuberculosis isolates fr

78 By use of IS6110 and the polymorphic GC-rich sequence (PGRS) as markers, it was found that pa

79 ll except one case shared common polymorphic GC-rich sequence (PGRS) patterns.

80 the probe pTBN12, containing the polymorphic GC-rich sequence (PGRS).

81 ific mycobacterial proteins with polymorphic GC-rich sequence (PGRS).

82 directed mutagenesis experiment identified a GC-rich sequence (position -58 to -46), which could be b

83 Mutations at the GC-rich sequences prevented binding of Sp1, and the indu

84 GTCT), whereas the Mad MH1 domains bind to a GC-rich sequence resembling Mad binding sites previously

85 , which alkylates DNA in the minor groove at GC-rich sequences resulting in an unusual bending toward

86 rine E-cadherin promoter through a conserved GC-rich sequence similar to an EGR-1 binding site as wel

87 l promoter in transfected cells and that the GC-rich sequences, spanning nucleotides -80 to -43, are

88 The GC-rich sequences surrounding the transcription initiati

89 Each repeat unit consists of a 7.3 kb GC-rich sequence that binds the insulator protein CTCF a

90 bind G-quartet structures but instead binds GC-rich sequences that are flexible in structure.

91 Tax binds to GC-rich sequences that immediately flank the CREs.

92 s the Im3lexitropsin bound non-covalently to GC-rich sequences, the triimidazole-BAM conjugate did no

93 The ability of this GC-rich sequence to form a large and stable secondary st

94 actor recognition sites, including multiple "GC-rich" sequences to which Sp1 factor binds and sequenc

95 In addition, we performed polymorphic GC-rich sequence typing (PGRS), spoligotyping, determina

96 promoter as a highly conserved 142-base pair GC-rich sequence upstream from the cap site.

97 ecipitation assays, have identified distinct GC-rich sequences used by KLF14 to regulate this promote

98 ct gene, which appeared to include extremely GC-rich sequences, using current RACE methods.

99 mapped to RNA2, as it was observed when the GC-rich sequence was inserted at downstream locations in

100 On the contrary, when the downstream GC-rich sequence was present only in the RNA3 component,

101 A GC-rich sequence which contains two overlapping Sp1 bind

102 three nontoxigenic strains contained a 17-bp GC-rich sequence which was not present in toxigenic stra

103 s (LBS1/2) and an adjacent 29- to 32-bp-long GC-rich sequence which we termed the replication element

104 BMH-21 binds GC-rich sequences, which are present at a high frequency

105 Pif1 did not promote synthesis through GC-rich sequences, which impede strand displacement.

106 of the Xenopus laevis TrbetaA gene has seven GC-rich sequences, which led us to hypothesize that BTEB

107 onal studies demonstrated that mutation of a GC-rich sequence within the 227-base pair conserved doma

108 ce analysis of the promoter region reveals a GC-rich sequence without a TATA motif and with putative