ライフサイエンスコーパス: GDP dissociation inhibitor

1 /SLY1-20 membranes remained sensitive to Rab GDP dissociation inhibitor.

2 either on membranes or in cytosol, bound to GDP dissociation inhibitor.

3 vating protein and ARF domains, may act as a GDP dissociation inhibitor.

4 of cultured cells is not associated with Rab GDP dissociation inhibitors.

5 horylation of Rab1 disrupts interaction with GDP dissociation inhibitor 1 (GDI1), but not guanine exc

6 beta8 integrin coimmunoprecipitates with Rho-GDP dissociation inhibitor 1 (RhoGDI1), an intracellular

7 calization and phosphorylation status of Rho GDP dissociation inhibitor 1 (RhoGDI1).

8 Rho GDP dissociation inhibitor 2 (RhoGDI2) has been identifi

9 A reduction in Rho GDP Dissociation Inhibitor 2 (RhoGDI2) protein has been

10 t inhibitor of Rho proteins known as the Rho-GDP dissociation inhibitor 2 (RhoGDI2).

11 and Rho1-GDP in vitro and that Msb3 and Rho GDP dissociation inhibitor act independently but opposit

12 acts through its two GoLoco motifs to exert GDP dissociation inhibitor activity over Galpha(i) subun

13 nding domains, and a GoLoco motif, which has GDP dissociation inhibitor activity.

14 in cell survival and proliferation, and Rho GDP dissociation inhibitor alpha (RhoGDIalpha), a member

15 Previous studies revealed that Rho GDP-dissociation inhibitor alpha (RhoGDIalpha) is involv

16 ory subunit/DJ-1 PARK7) and RhoGDIalpha (Rho GDP-dissociation inhibitor alpha).

17 ors of Gbetagamma signaling pathways, act as GDP dissociation inhibitors and negatively regulate the

18 pase substrates poly(ADP-ribose) polymerase, GDP dissociation inhibitor, and PKCdelta was observed wh

19 gration inhibitors Nme1, Nme2, and Nme3, the GDP dissociation inhibitor Arhgdib, and the metalloprote

20 s, including beta-lactate dehydrogenase, Rho GDP dissociation inhibitor beta, ATP synthase, elongatio

21 (TORC1), by its direct association with Rab GDP dissociation inhibitor beta, which likely regulates

22 TP-binding proteins of the rab family by rab GDP dissociation inhibitor completely abolishes formatio

23 The Rho GDP dissociation inhibitor D4-GDI is overexpressed in so

24 inhibition of Pak1 kinase activity and Rac1-GDP-dissociation inhibitor disassociation, and inhibitio

25 cytosol, and this effect was blocked by the GDP dissociation inhibitor for Rho (Rho-GDI).

26 ressing Rho GDIalpha, an endogenous specific GDP dissociation inhibitor for Rho family proteins, usin

27 ieved by expressing Rho GDIalpha, a specific GDP dissociation inhibitor for Rho family proteins, usin

28 that D4-GDI, an abundant hematopoietic cell GDP dissociation inhibitor for the Ras-related Rho famil

29 ates poly(ADP ribose) polymerase and D4-GDI (GDP dissociation inhibitor for the rho family), as well

30 roteins as nucleotide exchange factors or as GDP dissociation inhibitors for Galpha have been propose

31 results suggest that GPR proteins are potent GDP dissociation inhibitors for Gialpha-like Galpha subu

32 orm are kept soluble in the cytoplasm by the GDP dissociation inhibitor (GDI) chaperone.

33 tide exchange factor (GEF, Mon1-Ccz1), a Rab-GDP dissociation inhibitor (GDI) complex (prenylated Ypt

34 s both GTPase-accelerating protein (GAP) and GDP dissociation inhibitor (GDI) functions, and eIF2B is

35 TrkBT1 interacted with Rho GDP dissociation inhibitor (GDI) in vivo, but Flag-TrkBT

36 Rab-GDP dissociation inhibitor (GDI) is an important modulat

37 nction, was perturbed by modest increases in GDP dissociation inhibitor (GDI) levels.

38 The GDP dissociation inhibitor (GDI) solubilizes prenylated

39 is mediated by interaction with the protein GDP dissociation inhibitor (GDI) that binds to prenylate

40 Membrane-bound GDP-Rabs interact with GDP dissociation inhibitor (GDI), resulting in the disso

41 Rush also directly binds to Rab GDP dissociation inhibitor (Gdi), which is involved in t

42 red for Rab localization and function is Rab GDP dissociation inhibitor (GDI), which is proposed to r

43 efore a bi-functional protein that acts as a GDP dissociation inhibitor (GDI).

44 rab4 complexed with its cytosolic chaperone, GDP dissociation inhibitor (GDI).

45 ion and GTP hydrolysis on Cdc42Hs by the Rho GDP-dissociation inhibitor (GDI) is extremely sensitive

46 structure of the bovine alpha-isoform of Rab GDP-dissociation inhibitor (GDI), which functions in ves

47 are maintained in the cytosol by binding to GDP-dissociation inhibitor (GDI).

48 rmations bound to a cytosolic protein termed GDP-dissociation inhibitor (GDI).

49 or their function appears to be regulated by GDP-dissociation inhibitors (GDI), three of which have b

50 The GDP-dissociation-inhibitor (GDI) for Rho-like GTP-bindin

51 ns that regulate the Rab GTPase cycle-Gdi1p (GDP-dissociation inhibitor [GDI]) or Gyp1p/Gyp7p (GTPase

52 The GDP dissociation inhibitors (GDIs) represent an importan

53 ffinity to regulatory proteins including Rab GDP dissociation inhibitors (GDIs).

54 Guanosine diphosphate (GDP) dissociation inhibitors (GDIs), such as activators

55 Guanosine diphosphate (GDP)-dissociation inhibitors (GDIs) belong to one of thr

56 The Rho GDP-dissociation inhibitors (GDIs) negatively regulate R

57 GDP-dissociation inhibitors (GDIs) play a primary role i

58 GDP-dissociation inhibitors (GDIs) play a primary role i

59 lls, fails to form detectable complexes with GDP-dissociation inhibitors (GDIs).

60 -synuclein on synaptic vesicles and that the GDP dissociation inhibitor.Hsp90 complex that controls R

61 also demonstrated modulatory roles for Rac1/GDP dissociation inhibitor in glucose-stimulated insulin

62 Purified GDP-dissociation inhibitor inhibited homotypic lysosome

63 G protein binding region of Cavce possesses "GDP dissociation inhibitor-like activity" with the same

64 Here, we report that FeoB harbors a novel GDP dissociation inhibitor-like domain that specifically

65 CARD9 associated with the GDP-dissociation inhibitor LyGDI in phagosomes after bac

66 Ras from the PM, in a process reminiscent of GDP dissociation inhibitor-mediated membrane recycling o

67 sm that does not depend on GTP hydrolysis or GDP dissociation inhibitor-mediated recycling.

68 ficient Rab3a mutant, by a dominant-negative GDP dissociation inhibitor mutant unable to recycle Rab3

69 f Cdc42-guanosine diphosphate (GDP) from Rho GDP dissociation inhibitor or for the membrane recruitme

70 genous Cdc42 from Golgi membranes by the Rho-GDP dissociation inhibitor protein fails to solubilize I

71 s morphogenesis, we overexpressed bovine Rho GDP dissociation inhibitor (Rho GDI alpha), which serves

72 kinase 5 and consequent dissociation of Rho GDP dissociation inhibitor (Rho-GDI) from an ezrin/Rho-G

73 o GTPases activity, by overexpression of Rho GDP dissociation inhibitor (Rho-GDI), inhibited the stra

74 Rho-GDP dissociation inhibitors (Rho-GDI) are repressors of

75 ous Rac1 and two known binding partners, Rho GDP dissociation inhibitor (RhoGDI) and p21-activated ki

76 nts, we found that Rac1 dissociates from Rho GDP dissociation inhibitor (RhoGDI) and translocates to

77 The Rho GDP dissociation inhibitor (RhoGDI) can bind to small GT

78 We have investigated the effects of Rho GDP dissociation inhibitor (RhoGDI) on exocytosis induce

79 Rho GDP dissociation inhibitor (RhoGDI) plays an essential r

80 ned SCN1 and showed that SCN1 is a RhoGTPase GDP dissociation inhibitor (RhoGDI) that spatially restr

81 mechanisms underlying the ability of the Rho-GDP dissociation inhibitor (RhoGDI) to elicit the releas

82 XIAP depends on its interaction with the Rho GDP dissociation inhibitor (RhoGDI) via the XIAP RING do

83 ycling of the Rho GTPases is mediated by Rho GDP dissociation inhibitor (RhoGDI), which forms a stabl

84 ent in the interaction of Cdc42 with the Rho-GDP dissociation inhibitor (RhoGDI).

85 on of both RhoA and Rac1; an increase in Rho GDP-dissociation inhibitor (RhoGDI) binding in the absen

86 ecently shown that reduced expression of the GDP dissociation inhibitor, RhoGDI2, is associated with

87 by the transgenic overexpression of the Rho GDP dissociation inhibitor RhoGDIalpha.

88 volatile anesthetic, halothane, with the Rho GDP dissociation inhibitor (RhoGDIalpha), which binds th

89 uced into the cells was shown to bind to rab GDP dissociation inhibitor, suggesting that this pool of

90 D4-GDI is a Rho GDP dissociation inhibitor that is widely expressed in h

91 Rho-GDIs are a family of Rho GDP-dissociation inhibitors that are critical in modulat

92 b GTPases (by preincubation of vesicles with GDP dissociation inhibitor), together with cytosol immun

93 We then used immunodepleted cytosol and GDP dissociation inhibitor-treated vesicles to determine

94 itro extraction of rab4 (but not rab11) with GDP dissociation inhibitor was severely attenuated in NP

95 ed on Rab5a and phosphorylated EEA-1 and Rab GDP dissociation inhibitor, with the latter causing Rab5