コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 nder the association of Galpha subunits with GPR54.
2 roperties, or protein interaction network of GPR54.
3 le of inducing an LH surge in the absence of GPR54.
4 pocampal neurons, which are known to express GPR54.
7 cociously, and we describe the expression of GPR54 and KiSS-1 in the hypothalamus during the peripube
8 ree were homozygous for an L148S mutation in GPR54, and an unrelated proband with idiopathic hypogona
12 lated by neuronal activity and activation of GPR54 by kisspeptin may in turn contribute to sustain ba
13 We showed previously that the activation of GPR54 by kisspeptin-10 suppressed CXCR4-mediated chemota
14 that the activation of its cognate receptor GPR54 by kisspeptin-10 suppressed the capacity of the pr
15 Activation of the G-protein-coupled receptor GPR54 by kisspeptins during normal puberty promotes the
18 RH) secretion, and mutations or deletions of GPR54 cause hypogonadotropic hypogonadism in humans and
19 S) in the second intracellular loop (IL2) of GPR54 causes idiopathic hypogonadotropic hypogonadism, a
24 itative PCR data showing kisspeptin receptor GPR54 expression in the arcuate nucleus, and the attenua
26 y, we used female mice with deletions in the GPR54 gene [GPR54 knock-outs (KOs)] to test the hypothes
27 ome (KS), whereas mutations in the GNRHR and GPR54 genes cause idiopathic hypogonadotropic hypogonadi
29 ptin fibers, express the kisspeptin receptor GPR54 in the preoptic region, but not in the tuberal reg
39 t study examined how expression of KiSS1 and GPR54 is regulated in rat hippocampus, using in vivo and
41 the cognate ligand for the metastin receptor GPR54, is a peptide known to dramatically reduce metasta
44 and its cognate G protein-coupled receptor, GPR54 (kisspeptin receptor, Kiss-R), are critical for th
46 emale mice with deletions in the GPR54 gene [GPR54 knock-outs (KOs)] to test the hypothesis that kiss
47 e found that hormone-replaced gonadectomized GPR54 KO males and females displayed appropriate gender-
48 Interestingly, adult testosterone-treated GPR54 KO males displayed "female-like" numbers of tyrosi
51 onic GnRH/LH secretion would be disrupted in GPR54 KOs and that such animals would be incapable of sh
53 on the antimetastatic function of KiSS1 and GPR54 largely focused on the autocrine inhibition of cel
55 The activation of ROCK also contributed to GPR54-mediated apoptosis in 293 cells, and its effect wa
56 n histochemistry indicated robust KiSS-1 and GPR54 mRNA expression in the region of the arcuate nucle
57 n intact females, but not in agonadal males, GPR54 mRNA levels in the hypothalamus increased approxim
59 increased plasma LH levels in both Kiss1 and Gpr54 mutant male mice similar to the responses in wild-
61 kisspeptin receptor (KISS1R, formerly called GPR54), neurokinin B (TAC3), and the neurokinin B recept
65 e interaction of kisspeptin and its receptor GPR54 plays a crucial role in governing the onset of pub
67 ns and mice, a loss of function mutations of GPR54 prevents the onset of puberty and leads to hypogon
69 n and luciferase assays, we demonstrate that Gpr54 regulates NFAT2- and Sp1-mediated Bmp7 transcripti
71 ings are consistent with the hypothesis that GPR54 signaling by its cognate ligand in the primate hyp
73 discusses the latest ideas about kisspeptin-GPR54 signaling in the neuroendocrine regulation of repr
75 nts; however, the precise role of kisspeptin-GPR54 signaling in the regulation of gonadotropin secret
77 evelopment by androgens, we assessed whether GPR54 signaling is essential for sexual differentiation
78 KO) mice, we first tested whether kisspeptin-GPR54 signaling is necessary for male and female sexual
82 nduced by SDF-1 indicates that activation of GPR54 signaling may negatively regulate the role of CXCR
83 KOs)] to test the hypothesis that kisspeptin-GPR54 signaling provides the drive necessary for tonic G
86 also been shown in cells that do not express GPR54, suggesting a paracrine mechanism in which kisspep
87 ecapitulates the effects observed with L148S GPR54, suggesting the critical importance of this hydrop
88 GnRH neurons express the kisspeptin receptor GPR54 upon circuit formation, suggesting that the signal
93 the kisspeptins, and their cognate receptor, GPR54, which have been implicated in the regulation of G
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。