ライフサイエンスコーパス: GTC

22 Anti-GTC-90 antibodies inhibit the in vitro Golgi transport a

23 0 repeats) of CTG.CAG and CGG.CCG as well as GTC.GAC by primer extensions in vitro using DNA polymera

24 g RNAs and reduced the stability of tRNA(Asp(GTC)) We also demonstrate the importance of m(5)C in pla

25 tivation energies than corresponding [(CAG):(GTC)] duplexes of the same length.

26 under the influence of green tea catechins (GTC), which are suggested to offer chemopreventive and t

27 ecent data suggest that green tea catechins (GTCs) reduce acute UVR effects, but human trials examini

28 Green tea catechins (GTCs) with or without caffeine have been studied in rand

29 nges from +1.02 kcal/mol for GCG/CTC and CCG/GTC to +1.95 kcal/mol for TCC/ATG.

30 we obtained GPSC-derived tubular-like cells (GTCs) that were functional in vitro, as demonstrated thr

31 a combination of myoclonic and tonic-clonic (GTC) seizures.

32 Cog1/ldlBp, Cog2/ldlCp, Cog3/Sec34, and Cog5/GTC-90), three homologues of yeast Sec34/35 complex subu

33 zed include (a) the Golgi transport complex (GTC), identified in an in vitro membrane transport assay

34 kDa), which we term Golgi transport complex (GTC).

35 lished interobserver ground truth consensus (GTC) diagnosis for 499 previously diagnosed cases propor

36 zure or generalized tonic-clonic convulsion (GTC).

37 d respective glutamate transporter currents (GTCs) were induced by photolytic or synaptic glutamate r

38 h the triplet repeat sequences d(GAC)n and d(GTC)n also form hairpins, repeats of the double-stranded

39 nits than with odd numbers, whereas d(GAC).d(GTC) repeats showed no such alternation despite having t

40 RCTs that evaluated GTCs with or without caffeine and that reported BMI, bod

41 Studies that evaluated GTCs without concomitant caffeine administration did not

42 la/Val455, with 3 individuals homozygous for GTC (Val) in both groups.

43 d TM methods and interobserver variance from GTC, following College of American Pathology guidelines.

44 or work implicated the instability of a (GAC*GTC)5 tract in the cartilage oligomeric matrix protein (

45 A transcribed plasmid containing (GAC*GTC)49 repeats led to large deletions (>3 repeats) after

46 We postulate that small instabilities of GAC*GTC repeats are achieved through replicative slippage, w

47 anscription, the genetic instability of (GAC*GTC)49 repeats did not significantly differ from the opp

48 The genetic instability of (GAC*GTC)n (where n = 6-74) was investigated in an Escherichi

49 in, we report the first genetic study on GAC*GTC repeat instability describing two types of mutationa

50 eas large deletion events are found when GAC*GTC repeats are transcribed.

51 Relative to the GAC/GTC class not associated with disease, the order of fold

52 Comparing CAG/CTG loop structures with GAC/GTC structures, having similar hydrogen bonding but diff

53 eviously identified neutral polymorphism GCC/GTC coding for Ala/Val455, with 3 individuals homozygous

54 y used APRs include ACA, ACC, ATC, GCC, GCG, GTC and CAC, some of which were translation enhancers in

55 found to be CTG > GAC approximately = CAG > GTC for 10 repeats.

56 t-negative missense mutation (codon 22 GGC-->GTC; V22G) of the signaling adaptor protein Uncoordinate

57 The frequency of haplotype GTC (-881G/-826T/-297C) was significantly higher among A

58 The haplotype GTC of NFKBIA gene is associated with higher risk of ARD

59 ter adjustment for covariates, the haplotype GTC remained significantly associated with increased ris

60 Crude analysis showed that the haplotype GTC was significantly associated with higher risks of AR

61 A novel full-length GTC TFO was designed to bind simultaneously in parallel

62 ue 433, in the M4 domain) the database lists GTC which encodes a valine, while our putative 'wild-typ

63 50 mg encapsulated green tea extract (540 mg GTC) with 50 mg vitamin C or placebo twice daily for 3 m

64 In mice, GTCs injected after ischemic renal injury homed to the r

65 Protein-binding assays showed that 1 microM GTC TFO inhibited binding of nuclear transcription facto

66 of sequence motifs d(TGTCT(n)G) and d(TGT(n)GTC).

67 of the duplex by pushing out the T-bases of GTC's so that the opposite faces of each phenoxazone are

68 The beneficial effect of GTC on cancer cells could be confirmed by SECM, and the

69 A 5-25-fold higher frequency of GTC(val) to TTC(phe) transversions at codon 157 was foun

70 ons for oligomers containing GTTC instead of GTC are also consistent with the T-base displacement mod

71 Six weeks after ischemic injury, kidneys of GTC-treated mice had less fibrosis and inflammatory infi

72 Loops of GTC compared with CTG melt 9 degrees C lower and slip 6-

73 -90) that allowed us to identify a number of GTC-90 cDNAs.

74 The membrane-associated pool of GTC-90 is localized to the Golgi apparatus.

75 The administration of GTCs with caffeine is associated with statistically sign

76 stematic review and meta-analysis of RCTs of GTCs on anthropometric variables, including body mass in

77 for the CXG TR sequences than for the GAC or GTC TR sequences.

78 Oral GTC (1080 mg/d) with vitamin C over 3 mo did not signifi

79 , while slippage rates decrease in the order GTC > CAG approximately GAC > CTG.

80 bilities (in low salt) increase in the order GTC < CAG < GAC < CTG, while slippage rates decrease in

81 of similar length but opposing orientation (GTC*GAC)53 containing plasmid led to small instabilities

82 antly differ from the opposing orientation, (GTC*GAC)53.

83 A Val1483Ile polymorphism (GTC to ATC; allele frequency of A = 0.10) was associated

84 fter genetic upregulation of Kir4.1, somatic GTCs were found to be decreased.

85 ents but increased the amplitudes of somatic GTCs.

86 tional base pairs at the ends will stabilize GTC/GTC binding sites, and to d(TGTCAATTG) in which two

87 equence information from the 90-kDa subunit (GTC-90) that allowed us to identify a number of GTC-90 c

88 Subcellular fractionation indicates that GTC-90 exists in both membrane and cytosolic pools, with

89 Hydrodynamic properties suggest that GTC is approximately 800 kDa and nonglobular.

90 Current data do not suggest that GTCs alone positively alter anthropometric measurements.

91 lanar phenoxazone chromophore inserts at the GTC site by pushing out the T-base while the terminal G

92 which the planar phenoxazone inserts at the GTC site with a loop-out T base whereas the G base at th

93 TGTC) and d(TGTCTTTTGTCA) in stabilizing the GTC/GTC binding site for juxtaposing the two G bases for

94 with the genomic sequence suggests that the GTC-90 mRNA is alternatively spliced.

95 tosolic pool associated exclusively with the GTC complex.

96 nged codon 104 from ATC (Ile) in hGSTP1*A to GTC (Val) in hGSTP1*B and hGSTP1*C and changed codon 113

97 odons 73(GCC to ACC, Ala to Thr), 76 (GCC to GTC, Ala to Val), 85(GCT to ACT, Ala to Thr), 98(CAC to

98 t inserts ((CTG.CAG), (CGG.CCG), (GAA.TTC), (GTC.GAC), and (GTG.CAC)) of different lengths, orientati

99 ance was determined through assay of urinary GTC metabolite epigallocatechin glucuronide.

100 ease and a common A2M polymorphism, Val1000 (GTC)/Ile1000 (ATC), which occurs near the thiolester act

101 considerable reduction in ACTD affinity when GTC is replaced by GTTC in an oligomer, in line with the

102 placebo-controlled trial to examine whether GTCs protect against clinical, histologic, and biochemic

103 d, followed by interobserver comparison with GTC.