ライフサイエンスコーパス: Gly

1 stabilizers (cholesterol (CHO) or glycerol (GLY)).

2 to occur exclusively at N-terminal glycines (Gly).

3 le Phe-Gly formed only N-Cl-/ N, N-di-Cl-Phe-Gly.

4 e in water over 10 days except N,N-di-Cl-Phe-Gly.

5 leading to a detection limit of ~3 mg/mL for Gly.

6 t to the inhibitory effects of Z-d-Phe-l-Phe-Gly.

7 y in the M9-glucose medium supplemented with Gly.

8 M Fe(3+)+0.6mM H2O2) and a glycation system (GLY) (0.05-0.2mM Fe(3+)+0.05M glucose) for their ability

9 ation, SPC-CHO-0.5%HC had higher EE than SPC-GLY-0.25%HC (P < 0.05).

10 with GLY had the highest EE (74.54%) for SPC-GLY-0.25%HC (P < 0.05).

11 ibited higher stability than lyophilized SPC-GLY-0.25%HC during storage at 25 degrees C for 28 days.

12 repared films, the use of 0.5% Ca(2+), 0.75% Gly(1) and 7.5% Gly(2) is suggested as the optimum condi

13 ts were randomized to receive once-daily IND/GLY (110/50 mug) for 14 days, followed by 14 days of pla

14 oncogenic RAS mutations (such as at residues Gly(12), Gly(13), and Gln(61)) have the same impact on R

15 RAS mutations (such as at residues Gly(12), Gly(13), and Gln(61)) have the same impact on RAS signal

16 fusion protein by inserting mNeonGreen after Gly-134.

17 avin N5 and strong H-bond formation with the Gly-141 carbonyl.

18 its extracellular ligand-binding repeats at Gly(171) Asp(172).

19 ed through multiple amino acid residues, but Gly-171 and Leu-175 of P2 were more critical.

20 ing residues from RasGRP1/3 (Thr(7), Tyr(8), Gly(19), and Leu(21), respectively) conferred potent bin

21 O prosthetic group created from (189)Ala-Ser-Gly(191) residues and the bound l-phenylalanine and l-ty

22 he use of 0.5% Ca(2+), 0.75% Gly(1) and 7.5% Gly(2) is suggested as the optimum condition.

23 around Gly(3)-Phe(4) and a gamma-turn around Gly(2), providing spectroscopic evidence for the formati

24 inal residues of the chemokine XCL1 (Val(1), Gly(2), Ser(3), and Glu(4)) contribute a large fraction

25 he(11),Leu(16)]hGLP-2-(1-33)-NHEt), and 85 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NH-((CH2)

26 0),D-Phe(11),Leu(16)]hGLP-2-(1-33)-OH), 73 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NH2), 81

27 ),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NH2), 81 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NHEt), an

28 ),D-Thi(11),Phe(16)]hGLP-2-(1-30)-NH2), 72 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-OH), 73 (

29 Analogues 69 ([Gly(2),Nle(10),D-Thi(11),Phe(16)]hGLP-2-(1-30)-NH2), 72

30 hexapeptide and several regions upstream of Gly(215) that comprise residues of the interface surface

31 semitryptic peptide arising from cleavage at Gly(2196)-Leu(2197) We noted that this scissile bond is

32 In contrast, Gly-22 in the motif could be substituted by other small

33 Because Val-17, Gly-22, Leu-25, Asn-26, and Pro-29 are predicted to resi

34 However, the importance of Gly-221 for HABP2 activity is unclear.

35 21A, and G221S mutants to assess the role of Gly-221 in HABP2 catalysis.

36 ructure analysis, we identified Arg(237) and Gly(239) residues on the S2 of the VSD that form direct

37 In addition, substitution of Gly-245, Gly-247, and Gly-250 affects the amount of PutP

38 In addition, substitution of Gly-245, Gly-247, and Gly-250 affects the amount of PutP in the m

39 ition, substitution of Gly-245, Gly-247, and Gly-250 affects the amount of PutP in the membrane.

40 Substitutions of gly-262 and thr-269 in Hsp90beta with lysines convert Hs

41 characterized by a type II' beta-turn around Gly(3)-Phe(4) and a gamma-turn around Gly(2), providing

42 MP15 finger residues at this site (Arg(301), Gly(304), His(307), and Met(369)) enable potent activati

43 and with the peptide backbone of Ser-328 and Gly-329 from both subunits.

44 mpact of deletion and replacement mutants of Gly-457 and its two adjacent residues in GAT-1.

45 modeling showed that the stretch surrounding Gly-457 is likely to form a pi-helix.

46 ined by deleting positions on either side of Gly-457.

47 was also partially rescued upon deletion of Gly-457.

48 ore-lining helix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gati

49 whereas a low response of the corresponding Gly-4934 variants suggested loss of function.

50 Gly-4941 replacement with Lys resulted in channels havin

51 Here, we report that substitution of Gly-4941 with Asp or Lys results in functional channels

52 lix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gating by providi

53 lanine substitution of the conserved central Gly(6)-Gln(7) residues or by random sequence scrambling

54 fied that calpain-1 cleaves hERG at position Gly-603 in the S5-pore linker of hERG.

55 has three amino acid substitutions (Cys(27), Gly(608), and Pro(671)) within the full-length molecule.

56 n of a highly selective OXTR agonist [Thr(4),Gly(7)]-OXT to hippocampal slices resulted in an acute a

57 The disease-linked mutation of the hinge Gly(86), leading to abnormally high affinity for the tar

58 helial lineage markers (CD45, CD31, CD14 and Gly-A) and the epithelial marker EpCAM.

59 The method, called SPRINT-Gly, achieved consistent results between ten-fold cross

60 h 18 of the 20 common amino acids, including Gly, Ala, Ser, Thr, Asp, and Glu, which are relatively s

61 nd sterically hindered amino acid junctions (Gly, Ala, Trp, Glu).

62 A translation stress in cis triggered by the gly-ala repeat sequence of Epstein-Barr virus (EBV)-enco

63 apeptide H(2)N-(CH(2))(4)-CO-Pro-Leu-Arg-Phe-Gly-Ala-NH-CH(2)-Fc is the optimal probe for cathepsin B

64 r ion permeation pathway and buttresses the 'Gly-Ala-Ser' (GAS) constriction, thus providing a struct

65 bands from PAGE gels reveal an abundance of Gly/Ala/Ser/Thr repeats exemplified by a prominent, prev

66 GLY, alanine (ALA), and serine (SER) all resulted in rem

67 oyl)-Gly and N-(4-(p-methoxyphenyl)butanoyl)-Gly albumin-binding motifs generated HTK03121 and HTK031

68 eased photosynthesis, and up to 54-fold more Gly alongside several redox-stress-related metabolites.

69 Crystal structures of Gly-AMP, Pro-AMP, betaPro-AMP and Phe-AMP bound to RNase

70 ty of the GlcN-amino acid combinations; GlcN-Gly and GlcN-Ser were best discriminated.

71 The peptides were rich in Glu, Asp, Lys, Gly and Leu, and also exhibited diverse bioactivities, a

72 ng group with N-(4-(p-chlorophenyl)butanoyl)-Gly and N-(4-(p-methoxyphenyl)butanoyl)-Gly albumin-bind

73 6 bearing the N-(4-(p-chlorophenyl)butanoyl)-Gly and N-(4-(p-methoxyphenyl)butanoyl)-Gly motifs, resp

74 types were detected with PyC(2)-Gly, PyC(3)-Gly and PyC(2)-Ala at quantifiable concentrations.

75 (i) the critical spacer length (longer than Gly) and (ii) the presence of Ca(2+) and Mg(2+) in all i

76 GRCl) was tested in the presence of glycine (GLY) and other selected amino acids.

77 m specific tRNA loci (e.g., the nuclear tRNA(Gly) and tRNA(Leu), the mitochondrial tRNA(Val) and tRNA

78 sequence comprising a central block (Pro-Hyp-Gly) and two positively charged domains (Pro-Arg-Gly) at

79 l (PG), dimethyl sulfoxide (DMSO), glycerol (GLY), and methanol (METH; listed in order from least to

80 abolism (2-hydroxybutanoic acid, oxoproline, Gly, and Glu) were altered in UCP3 Tg mice across all tr

81 teins, hyperaccumulation of photorespiratory Gly, and reduced accumulation of many intermediates in c

82 ing every amino acid residue to Val, Ala, or Gly, and then screening the drug resistance phenotypes o

83 tification of three dipeptides, Tyr-Gly, Phe-Gly, and Tyr-Ala, from raw water demonstrates a useful a

84 ndwiched between two neighboring glycines (a Gly-Arg-Gly, or "GRG," sequence).

85 sp at position 177, Gln/Glu at position 180, Gly/Arg at position 239, and Pro/Ser at position 280.

86 ion was also significantly improved with IND/GLY, as evidenced by a 12.4% increase versus placebo (P

87 Although Arg-Gly-Asp (RGD) integrin ligand and matrix softening confe

88 independently of IGF binding through an Arg-Gly-Asp (RGD) integrin-binding motif.

89 C3 harbors an Arg-Gly-Asp (RGD) motif, which is the major integrin-binding

90 migration by targeting integrins, using Arg-Gly-Asp (RGD) peptide-functionalized gold nanorods.

91 Cyclic peptides containing the Arg-Gly-Asp (RGD) sequence have been shown to specifically b

92 ful intermediates for the preparation of Arg-Gly-Asp (RGD)-based cyclopentapeptides (cRGD) with nanom

93 In contrast, the putative Arg-Gly-Asp (RGD)-binding alphaPAT-2/betaPAT-3 integrin was

94 classes of integrins: collagen-binding, Arg-Gly-Asp (RGD)-binding, laminin-binding, and leukocyte in

95 th a higher affinity compared with other Arg-Gly-Asp binding integrins.

96 Additionally, the Gly-Asp insertion impairs bacterial growth in lactose-co

97 ttings drives the expansion of KP expressing Gly-Asp insertion mutants, despite an associated fitness

98 ocal stresses on the cell surface via an Arg-Gly-Asp-coated magnetic bead.

99 d lipid domains increased beta1-integrin-Arg-Gly-Asp-peptide affinity and valency, thus implicating L

100 elial cells, BA increased beta1-integrin-Arg-Gly-Asp-peptide affinity by 18% with a transition from s

101 XAT contains a canonical Gly-Asp-Ser-Leu (GDSL) motif and is encoded by a member

102 is highly preferred for binding to conserved Gly:Asp:Asn residues.

103 0), including a preference for Ser, Arg, and Gly at the +1 and a preference for Arg at the +7 positio

104 homologs which contained either an Ile or a Gly at this location and showed that only the Gly-contai

105 and two positively charged domains (Pro-Arg-Gly) at both N- and C-termini.

106 mologous candidate genes, glycogen synthase (glys), atp-binding cassette transporter (atp), and low-d

107 -Ser, -Val and the three achiral amino acids Gly, beta-Ala, and GABA).

108 e traditional beta-turn motifs such as d-Pro-Gly, both the 2-Abz and d-Phe rings may be further funct

109 GlcN-Gly caramels generated the greatest amount of butterscot

110 Strict L-chiral rejection through Gly-cisPro motif during chiral proofreading underlies th

111 PyC(2)-Gly concentrations were highest in fruits and root veget

112 ly at this location and showed that only the Gly-containing desaturase was capable of very-long-chain

113 ing infection, including the cleavage of Phe/Gly-containing nucleoporin proteins (Nups) within nuclea

114 I viral fusion proteins, including high Ala/Gly content, intermediate hydrophobicity, and few charge

115 ft from high-to-low CO(2) without changes in Gly decarboxylase (GDC) gene or protein expression.

116 d ultrastructure, and tissue localization of Gly decarboxylase subunit P (GLDP) in nine Neurachninae

117 rial proteins in mtacp mutants, particularly Gly decarboxylase, affects the recovery of photorespirat

118 ibutions of the activation loop, the Asp-Phe-Gly (DFG) motif, the regulatory spine, and the gatekeepe

119 type I inhibitors assume an active "Asp-Phe-Gly (DFG)-in" and "alphaC-in" conformation.

120 scopy study on the stepwise hydration of the Gly dimer with up to three water molecules.

121 ructural explanation for the role of the His-Gly dipeptide in the structure and function of ASICs.

122 protocols for the preparation of various Xaa-Gly dipeptide surrogates in the form of Xaa-psi[triazole

123 lasmic linker protein 170 (CLIP170) is a CAP-Gly domain-containing protein that is associated with th

124 In the tested conditions, the GLY environment was more effective than the HRGS system

125 the small hydrophobic peptide Z-d-Phe-l-Phe-Gly (FIP) was shown to block MeV infections and syncytiu

126 , and N-Cl-3-I-tyrosyl dipeptides, while Phe-Gly formed only N-Cl-/ N, N-di-Cl-Phe-Gly.

127 played enhanced innervation in mice on a Ser/Gly-free diet.

128 The inhibitors carbobenzoxy (Z)-d-Phe-l-Phe-Gly (fusion inhibitor peptide [FIP]) and 4-nitro-2-pheny

129 The Gly gatekeeper of CDPK1 makes it exquisitely sensitive t

130 dentified a role for one specific tRF-5' tRF-Gly-GCC, or tRF-GG-as a repressor of genes associated wi

131 endent on stretches of rare codons, Leu(UUA)-Gly(GGU)-Val(GUA).

132 work (MOF) based on the tripeptide Gly-l-His-Gly (GHG) for the enantioselective separation of metamph

133 omprising a formamidinylated, N-hydroxylated Gly-Gln dipeptide conjugated to 6'-amino-pseudouridine.

134 cids in all fractions were dominated by Ala, Gly, Glu and Ser.

135 We identify a Lys-Gly-Glu (KGE) integrin-binding motif in the FVIIa protea

136 r protein that binds RNA through RRM and Arg-Gly-Gly (RGG) motifs.

137 omodimers FemA and FemB sequentially add two Gly-Gly dipeptides.

138 proRaxX is cleaved at a Gly-Gly motif, yielding a mature peptide that retains th

139 irulence peptide 1 (vp1), a highly expressed Gly-Gly peptide-encoding gene in chinchilla middle ear e

140 The Arg-Gly-Gly repeats within the low-complexity region are req

141 N-unsubstituted alpha-amino acids, dipeptide Gly-Gly, and also benzylamine were used as the amine com

142 water which combines the selectivity of the Gly-Gly-His (GGH) peptide probe with the sensitivity of

143 which recognizes the pan-opioid sequence Tyr-Gly-Gly-Phe at the N terminus of most endogenous opioid

144 % MS SI restoration for the Z-Gly-Gly-Val and bradykinin peptides were 75-83% while %

145 ethanediyl)]dipyridine, en = ethylendiamine, gly = glycinate, and acac = acetylacetonate, have been s

146 Ser (exSer)-dependent PDAC cells during Ser/Gly (glycine) deprivation.

147 ies, reveal how the flexibility of a Gly-Met-Gly (GMG) motif in the unwound region of transmembrane s

148 phorus limited, which was indicated by a PHO:GLY greater than 154 under the conditions tested in this

149 The Gly -> Arg substitution destabilized CMP-alpha(2)I side-

150 P-alpha(2)I side-chain interactions, and the Gly -> Val change broke the essential Mg(2+) coordinatio

151 tic peptides (CMPs) with previously reported Gly -> Xaa (Xaa = Ala, Arg, or Val) vEDS substitutions w

152 MD simulations suggested that bulkier Gly -> Xaa substitutions differentially disrupt the CMP-

153 cluster consisting of six genes, gtf1, gtf2, gly, gtf3, dGT1 and galT2.

154 cluster consisting of six genes: gtf1, gtf2, gly, gtf3, dGT1, and galT2 Mature Fap1 glycan possesses

155 05) (85.42%), while liposome stabilized with GLY had the highest EE (74.54%) for SPC-GLY-0.25%HC (P <

156 SIC1 that includes the highly conserved 'His-Gly' (HG) motif.

157 aniline-diglycolic acid-DPhe-Gln-Trp-Ala-Val-Gly-His-Leu-NHEt), showing excellent tumor localizing ef

158 rboxymethyl-piperidine-d-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 ((68)Ga-RM2) is a synthetic bombesin

159 am-positive bacteria lack C-terminal Gly-Tyr-Gly-Ile motifs, suggesting that they do not interact wit

160 lusions: Pharmacologic intervention with IND/GLY improves pulmonary microvascular blood flow and regi

161 highly selective CCK-2R agonist by replacing Gly in a CCK-8 derivative with Glu.

162 Substitution of Tyr for Ala and Gly in ADS1.2 and ADS1.4, respectively, blocked their ab

163 he presence of the proximal l-Ala instead of Gly in the common configuration of the peptide side chai

164 An absolutely conserved Gly in the middle of the alpha1-helix of betaI helps mai

165 he or Leu at the C-terminal P2' position and Gly in the P6 position.

166 ATP and Gly induced common, but also specific, alternative modes

167 Overall, SPRINT-Gly is 18% and 50% higher in Matthews correlation coeffi

168 Glycine (Gly) is used as a model system to evaluate the ability o

169 The experimental results of ligation at Gly junction and regioselective ligation at Glu junction

170 y 1,2-hydroxyl-functionalized l-glycerate (l-gly, l-HOCH(2)(HO)CHCO(2)(-)) was investigated by van't

171 anic framework (MOF) based on the tripeptide Gly-l-His-Gly (GHG) for the enantioselective separation

172 ase to total glycosidase activity ratio (PHO:GLY), led to 230% higher headloss accumulation rate when

173 emonstrate abnormally elevated brain Glu and Gly levels in patients with first-episode psychosis by m

174 Significantly higher Glu and Gly levels were found in both the anterior cingulate cor

175 Glu and Gly levels were measured in vivo in the anterior cingula

176 Glu and Gly levels were positively correlated in patients.

177 uantify in vivo glutamate (Glu) and glycine (Gly) levels in patients with first-episode psychosis as

178 ing the capsule to its host capacity of 24 l-gly ligands via an entropically driven hydrophobic respo

179 conformation, whereas in the CD loop mutant "Gly-loop", the original network of interactions between

180 y the parasite-secreted kinase WNG1 (With-No-Gly-loop) as a critical regulator of tubular membrane bi

181 ny dose level, sIgE/IgG4 against Bet v 1 and Gly m 4.

182 ed only in active group (Bet v 1: P = 0.054, Gly m 4: P = 0.037), and no relevant changes occurred fo

183 s on overlapping and recombinant peptides of Gly-m-Bd-30K by SPOT and cell proliferation assays.

184 lk allergy with the oral administration of a Gly-m-Bd-30K soy-derived peptide that contains cross-rea

185 cosylation by adding a rhamnose residue, and Gly mediates the final glycosylation step by transferrin

186 nal studies, reveal how the flexibility of a Gly-Met-Gly (GMG) motif in the unwound region of transme

187 The consequent Gly-tRNA(Gly) 'misediting paradox' is resolved by EF-Tu in the ce

188 N-terminal peptidase C39 domain at a double Gly motif.

189 Since only subsets of Phe/Gly motifs, particularly those within Nup62, Nup98, and

190 oyl)-Gly and N-(4-(p-methoxyphenyl)butanoyl)-Gly motifs, respectively, had relatively faster tumor ac

191 t, contrary to previous reports, the Asp(614)Gly mutation in the spike glycoprotein (S) likely reduce

192 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-

193 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly,

194 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N-Cl-Tyr-Ala, and

195 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly, N-Cl-Tyr-Ala, and

196 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-Ala a

197 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-Ala along with thei

198 N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-Ala were identified

199 Rare N-gly-negative subclones were lost or negligible from succ

200 ated three mutant forms (I14X; X = Val, Ala, Gly) of the enzyme that have increased active site flexi

201 nd to the morphine and D-Ala(2), N-MePhe(4), Gly-ol]-enkephalin (DAMGO) nonbiased agonists and to the

202 ivation by morphine or [d-Ala(2),N-MePhe(4), Gly-ol]enkephalin (DAMGO) causes differences in spatiote

203 ermine the effect of lung deflation with IND/GLY on PMBF and regional pulmonary ventilation using mag

204 y charged Arg, Lys, Glu, and Asp residues by Gly or His.

205 between two neighboring glycines (a Gly-Arg-Gly, or "GRG," sequence).

206 ination compounds [Ru(en)(pdto)]Cl2 (1), [Ru(gly)(pdto)]Cl (2), and [Ru(acac)(pdto)]Cl (3), where pdt

207 and quantification of three dipeptides, Tyr-Gly, Phe-Gly, and Tyr-Ala, from raw water demonstrates a

208 The selection and expansion of only N-gly-positive subclones is evidence of the tumor cells' d

209 ble from successive events, in contrast to N-gly-positive subclones, which could additionally migrate

210 triple helix conformation and stabilisation (Gly, Pro, Hyp and Hyl), whilst the Lys content was great

211 Mutations in ClC-Ka that change Ser(cen) to Gly, Pro, or Thr have only minor effects on anion select

212 degrading the neutrophil chemoattractant Pro-Gly-Pro (PGP) and rationalized that the failure of conve

213 we report that the matrikine acetylated Pro-Gly-Pro (PGP) stimulates vascular inflammation through a

214 Examination of aza-Gly-Pro and aza-Phe-Pro analogs 2a and 2b in a murine pr

215 To our knowledge, the peptides Gly-Pro-Ala-Val, Val-Cys, and Phe-Phe have not been prev

216 presence and absence of the fibrin inhibitor Gly-Pro-Arg-Pro.

217 d inactivates the chemotactic tripeptide Pro-Gly-Pro.

218 ely 10% in comparison to benchmark method of Gly-PseAAC.

219 Five PyC types were detected with PyC(2)-Gly, PyC(3)-Gly and PyC(2)-Ala at quantifiable concentra

220 antigens in four patients, glycine receptor (GLY-R) in 5 patients, N-methyl-d-aspartate receptor in 4

221 ase (GAD65, amphiphysin); glycine receptors (GLY-R); water channels (AQP4).

222 nine (Tyr-Ala), and phenylalanylglycine (Phe-Gly), reacted with sodium hypochlorite, and these reacti

223 he molecular pathways leading to enhanced PG/GLY reactivity are described, along with the most impact

224 the dynamics of the major amino acids, e.g., Gly, remained unaltered with respect to parity.

225 trinsically disordered proteins, such as Phe-Gly repeat domains, alters drastically when they are con

226 zation and solid-state assays indicated that Gly replacements at four sites within the Fn-binding seq

227 In contrast, Gly replacements N-terminal to the GFPGER sequence, up t

228 Glycoaldehyde (Gly) represents a prototypical system to identify the re

229 examined using various amino acids, and only Gly required the optimization of the Fmoc removal cockta

230 Mutations at a Gly residue (Gly150) that modulate helical mobility redu

231 ond and ligates protein-LPXT to the terminal Gly residue of the nascent cross-bridge of peptidoglycan

232 optimized protocol used to remove Fmoc from Gly residue was proved by the synthesis of Leu-enkephali

233 Replacement of Gly residues C-terminal to GFPGER did not affect integri

234 Gly to Ser mutations within the two Gly residues in the essential GFPGER sequence prevented

235 Peptides carrying multiple Pro and Gly (residues with lowest helical propensity) retain str

236 ants in which Tyr-15 is replaced with Ala or Gly, respectively, are monomeric.

237 opsis, ADS1.2 and ADS1.4, which have Ala and Gly, respectively, in place of the gatekeeping Tyr found

238 ntains an RRM domain at the N terminus and a Gly-rich domain at the C terminus.

239 The N-terminal Gly-rich fragment of rSp0032 and the C-terminal His-rich

240 mbrane and coiled coil regions by a flexible Gly-rich linker.

241 omplexed with AMP-PNP reveals a shift in the Gly-rich loop along with domain closure to position the

242 s (amino acids [aa] 19 to 40) of p17 and the Gly-rich region of the C terminus of hnRNP A1.

243 (TTLL5) glutamylates RPGR(ORF15) in its Glu-Gly-rich repetitive region containing motifs homologous

244 with reduced amino acid diversity, foremost Gly, Ser, and Thr.

245 FmhC pair with FemA and FemB to incorporate Gly-Ser dipeptides into cross-bridges and to confer resi

246 mutation of tyrosine residues in Gly/Ser-Tyr-Gly/Ser motifs of the IDR reduced this effect, depending

247 Systematic mutation of tyrosine residues in Gly/Ser-Tyr-Gly/Ser motifs of the IDR reduced this effec

248 the carbonyl groups from the Thr-Val-Gly-Tyr-Gly signature filter sequence and the permeant ions gene

249 ilation with indacaterol/glycopyrronium (IND/GLY) significantly reduced hyperinflation, which transla

250 To elucidate the significance of N-gly site presence and loss during ongoing SHM, we tracke

251 sulting DNA sequences still encoded for an N-gly site.

252 We observed conservation of N-gly sites in more than 96% of subclone populations withi

253 Ongoing SHM of the N-gly sites resulted in subclones with different amino aci

254 N-gly sites were gained in the earliest identified lymphom

255 ation sites asparagine-X-serine/threonine (N-gly sites) within the V-region that are rarely found in

256 the 2D-IR spectrum allows separation of the Gly spectral signature from that of the dominant protein

257 Whereas a single Gly substitution caused transient breaks ~20% of the tim

258 ent breaks ~20% of the time, two consecutive Gly substitutions break the helix ~65% of the time.

259 glucose homeostasis (GLUT-4, G6PDH, Hk-2 and Gly-Syn-1).

260 In Staphylococcus aureus, a species-specific glyS T-box controls the supply of glycine for both ribos

261 of RPGR (RPGR(ORF15)), carrying multiple Glu-Gly tandem repeats and a C-terminal basic domain of unkn

262 We found that PB-Gly-Taxol bound the target protein beta-tubulin with bot

263 tagging") of LPXTG-containing substrates and Gly-terminated nucleophiles occurs in vitro as well as i

264 should be more compounds produced by PG and GLY than have been reported in e-cigarette aerosols to d

265 solvents propylene glycol (PG) and glycerol (GLY), thereby affording unique product profiles as compa

266 Through a facile Gly to Pro substitution, we have altered backbone dynami

267 Whereas previous studies showed that Gly to Ser mutations within an integrin-binding site cau

268 Gly to Ser mutations within the two Gly residues in the

269 Constructs with Gly to Ser substitutions within and nearby the inserted

270 null effect observed for the small subset of Gly-to-d-Ala substitutions which are not stabilizing.

271 photorespiratory CO(2) release and impaired Gly-to-Ser turnover after a shift from high-to-low CO(2)

272 unit through sequential additions of Pro-Hyp-Gly triads, we achieved sub-angstrom tuning over the 2D

273 ATP and Gly triggered changes in the expression of the genes inv

274 ing in collagen peptides composed of Pro-Hyp-Gly triplet repeats, allowing for truncation to the smal

275 a subset of tRNAs, including tRNA(Glu), tRNA(Gly), tRNA(Lys), tRNA(Val), tRNA(His), tRNA(Asp), and tR

276 Moreover, DTD's activity on non-cognate Gly-tRNA(Ala) is conserved across all bacteria and eukar

277 architecture can efficiently edit mischarged Gly-tRNA(Ala) species four orders of magnitude more effi

278 The consequent Gly-tRNA(Gly) 'misediting paradox' is resolved by EF-Tu

279 Methods: DOTA-D-Glu-Ala-Tyr-Gly-Trp-(N-Me)Nle-Asp-1-Nal-NH(2) (DOTA-MGS5) radiolabel

280 (177)Lu-DOTA-MG11 ((177)Lu-DOTA-dGlu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH(2)) and (177)Lu-DOTA-PP-F11 ((177

281 -DOTA-PP-F11 ((177)Lu-DOTA-(dGlu)(6)-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH(2)), and whether the use of prote

282 DOTA-PP-F11N ((177)Lu-DOTA-(dGlu)(6)-Ala-Tyr-Gly-Trp-Nle-Asp-Phe-NH(2)) performs better than referenc

283 strin analog (177)Lu-DOTA-(d-Glu)(6)-Ala-Tyr-Gly-Trp-Nle-Asp-PheNH(2) ((177)Lu-PP-F11N) is a suitable

284 between the carbonyl groups from the Thr-Val-Gly-Tyr-Gly signature filter sequence and the permeant i

285 from Gram-positive bacteria lack C-terminal Gly-Tyr-Gly-Ile motifs, suggesting that they do not inte

286 three model dipeptides, tyrosylglycine (Tyr-Gly), tyrosylalanine (Tyr-Ala), and phenylalanylglycine

287 romatic dipeptides, phenylalanylglycine (Phe-Gly), tyrosylalanine (Tyr-Ala), and tyrosylglycine (Tyr-

288 the products derived from vaporizing PG and GLY under mild, single puff conditions.

289 ylalanine (Tyr-Ala), and tyrosylglycine (Tyr-Gly), under chloramination in the presence of Br(-) and

290 At pD 5.8, l-gly uptake is enthalpically inhibited.

291 between 0.004 and 0.022) in response to IND/GLY versus placebo.

292 ctively, in patients with COPD receiving IND/GLY versus placebo.

293 PyC(2)-Gly was found at the highest concentrations and most wid

294 supplemented with varying concentrations of Gly were obtained, and a range of data analysis methods

295 ceptor ligand, analogs H-Tyr-c[D-Lys-Xxx-Tyr-Gly] were synthesized and their biological activity was

296 mming included a higher rate of metabolizing Gly, which provides additional evidence that the metabol

297 the self-assembly of type I collagen via the Gly-X-Y motif, the molecular mechanism by which enamel m

298 ain, which is defined by the presence of the Gly-X-Y triplet repeats, is amongst the most versatile a

299 gth pinholin protein before being triggered (Gly-zipped TMD2/TMD1-TMD1/TMD2 dimer in a line).

300 bundle), for the active dimer (right-handed Gly-zipped TMD2/TMD2 dimer), and for the full-length pin