ライフサイエンスコーパス: Gly

1 d displaying a terminal carboxylic acid (DBS-Gly).

2 gamma-aminobutyric acid (GABA) and glycine (GLY).

3 e in water over 10 days except N,N-di-Cl-Phe-Gly.

4 very different distributions of FAA- and PAA-Gly.

5 he evolutionary replacement of Ala(241) with Gly.

6 dons coding for Ser, Arg, Leu, Pro, Thr, and Gly.

7 t to the inhibitory effects of Z-d-Phe-l-Phe-Gly.

8 M Fe(3+)+0.6mM H2O2) and a glycation system (GLY) (0.05-0.2mM Fe(3+)+0.05M glucose) for their ability

9 major C3S (Arg(102)) and disease-linked C3F (Gly(102)) allotypes of C3b were experimentally explained

10 lu(1066)), P2 (Asp(1090)-Cys(1104)), and P3 (Gly(1127)-Cys(1140))).

11 avin N5 and strong H-bond formation with the Gly-141 carbonyl.

12 sly at near-neutral and basic pH and Asn(16)-Gly(17) rather at basic pH.

13 ed through multiple amino acid residues, but Gly-171 and Leu-175 of P2 were more critical.

14 ing residues from RasGRP1/3 (Thr(7), Tyr(8), Gly(19), and Leu(21), respectively) conferred potent bin

15 O prosthetic group created from (189)Ala-Ser-Gly(191) residues and the bound l-phenylalanine and l-ty

16 ergoes self-cleavage between the periplasmic Gly-191 and Thr-192 residues independent of the percepti

17 e is required for an attack on the preceding Gly-191, after which the resulting ester bond is likely

18 around Gly(3)-Phe(4) and a gamma-turn around Gly(2), providing spectroscopic evidence for the formati

19 he(11),Leu(16)]hGLP-2-(1-33)-NHEt), and 85 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NH-((CH2)

20 0),D-Phe(11),Leu(16)]hGLP-2-(1-33)-OH), 73 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NH2), 81

21 ),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NH2), 81 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NHEt), an

22 ),D-Thi(11),Phe(16)]hGLP-2-(1-30)-NH2), 72 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-OH), 73 (

23 Analogues 69 ([Gly(2),Nle(10),D-Thi(11),Phe(16)]hGLP-2-(1-30)-NH2), 72

24 hexapeptide and several regions upstream of Gly(215) that comprise residues of the interface surface

25 However, the importance of Gly-221 for HABP2 activity is unclear.

26 21A, and G221S mutants to assess the role of Gly-221 in HABP2 catalysis.

27 The presence of Gln(180) and Gly(239), as in HLA-A2, led to higher cell surface expre

28 (241) alleles) and CELA3B ( approximately 2% Gly(241) alleles) points to individual variations in com

29 cAtg4.2, including mutation of the conserved Gly-244 residue in the hinge region enabling flexibility

30 In addition, substitution of Gly-245, Gly-247, and Gly-250 affects the amount of PutP

31 In addition, substitution of Gly-245, Gly-247, and Gly-250 affects the amount of PutP in the m

32 ition, substitution of Gly-245, Gly-247, and Gly-250 affects the amount of PutP in the membrane.

33 Substitutions of gly-262 and thr-269 in Hsp90beta with lysines convert Hs

34 ase (the LacY double-Trp mutant Gly-46-->Trp/Gly-262-->Trp) with bound p-nitrophenyl-alpha-d-galactop

35 [BrPhe(22)]sCT(8-32) adopts a type II turn (Gly(28)-Thr(31)), whereas CGRP and AM adopt type I turns

36 included two dipeptides (Gly-Phe (2) and Phe-Gly (3)), as well as a thiolated dipeptide analogue (4)

37 ve the turn where it can form H-bonds to the Gly(3) and C-terminus C horizontal lineO groups.

38 characterized by a type II' beta-turn around Gly(3)-Phe(4) and a gamma-turn around Gly(2), providing

39 nized monoclonal antibody KD-247 targets the Gly(312)-Pro(313)-Gly(314)-Arg(315) arch of the third hy

40 ntibody KD-247 targets the Gly(312)-Pro(313)-Gly(314)-Arg(315) arch of the third hypervariable (V3) l

41 g site is located in the vicinity of residue Gly(33), a residue involved in Met(35) oxidation.

42 ted interaction centered on residues Phe-36, Gly-37, Thr-58, Trp-59, and Lys-60.

43 ted peptide (CabTRP Ia, Ala(1)-Pro(2)-Ser(3)-Gly(4)-Phe(5)-Leu(6)-Gly(7)-Met(8)-Arg(9)-NH2).

44 mpact of deletion and replacement mutants of Gly-457 and its two adjacent residues in GAT-1.

45 modeling showed that the stretch surrounding Gly-457 is likely to form a pi-helix.

46 ined by deleting positions on either side of Gly-457.

47 was also partially rescued upon deletion of Gly-457.

48 nenzymatic deamidation, the sequence Asn(45)-Gly(46) being deamidated spontaneously at near-neutral a

49 lactose permease (the LacY double-Trp mutant Gly-46-->Trp/Gly-262-->Trp) with bound p-nitrophenyl-alp

50 rmed the new hydrogen bond interactions with Gly 48 in the flap of the enzyme.

51 ore-lining helix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gati

52 whereas a low response of the corresponding Gly-4934 variants suggested loss of function.

53 Gly-4941 replacement with Lys resulted in channels havin

54 Here, we report that substitution of Gly-4941 with Asp or Lys results in functional channels

55 lix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gating by providi

56 via interactions with residues within TMS1 (Gly(56), Thr(57)), TMS3 (Glu(138)), and TMS6 (Phe(248)),

57 lanine substitution of the conserved central Gly(6)-Gln(7) residues or by random sequence scrambling

58 fied that calpain-1 cleaves hERG at position Gly-603 in the S5-pore linker of hERG.

59 a, Ala(1)-Pro(2)-Ser(3)-Gly(4)-Phe(5)-Leu(6)-Gly(7)-Met(8)-Arg(9)-NH2).

60 n of a highly selective OXTR agonist [Thr(4),Gly(7)]-OXT to hippocampal slices resulted in an acute a

61 Deletion of Gly-720 and Tyr-721 from a highly conserved GYxxO traffi

62 The first new element (Gly-807-Gly-811) is short distance element on the C-term

63 The first new element (Gly-807-Gly-811) is short distance element on the C-terminal sid

64 2)-Ser(3)-Lys(4)-Pro(5)-Asp(6)-Asn(7)-Pro(8)-Gly(9)-NH2) and a tachykinin-related peptide (CabTRP Ia,

65 helial lineage markers (CD45, CD31, CD14 and Gly-A) and the epithelial marker EpCAM.

66 iggers assembly of DBS-CO2H, followed by DBS-Gly; a good degree of kinetic self-sorting is achieved.

67 ergistically transport highly polar glycine (Gly) across vesicle membranes.

68 e tetrapeptide substrates acetyl-Lys-Lys-Cha-Gly-AFC (Ac-KKChaG-AFC) and acetyl-Lys-Thr-Cha-Gly-AFC (

69 y-AFC (Ac-KKChaG-AFC) and acetyl-Lys-Thr-Cha-Gly-AFC (Ac-KTChaG-AFC).

70 h 18 of the 20 common amino acids, including Gly, Ala, Ser, Thr, Asp, and Glu, which are relatively s

71 A translation stress in cis triggered by the gly-ala repeat sequence of Epstein-Barr virus (EBV)-enco

72 RNA foci, inclusions of poly(Gly-Pro), poly(Gly-Ala), and poly(Gly-Arg) dipeptide repeat proteins, a

73 These reactions build up H2N-Pro-Gly-Ala-CONHL and H2N-Cys-His-Asp-CONHL (where L = organ

74 bands from PAGE gels reveal an abundance of Gly/Ala/Ser/Thr repeats exemplified by a prominent, prev

75 GLY, alanine (ALA), and serine (SER) all resulted in rem

76 both the hemiaminal and imine formed between Gly and an aldehyde.

77 The nonessential amino acids Gly and Glu, and the essential amino acid Ile were more

78 Rates of GLY and GNG increase during exercise in athletes followi

79 peptide libraries Ser-[X]4-Gly-Gly-Gly, with Gly and Ser encoded using unique combinations of codons

80 (i) the critical spacer length (longer than Gly) and (ii) the presence of Ca(2+) and Mg(2+) in all i

81 ion (EGP) occurs via hepatic glycogenolysis (GLY) and gluconeogenesis (GNG) and plays an important ro

82 GRCl) was tested in the presence of glycine (GLY) and other selected amino acids.

83 m specific tRNA loci (e.g., the nuclear tRNA(Gly) and tRNA(Leu), the mitochondrial tRNA(Val) and tRNA

84 sequence comprising a central block (Pro-Hyp-Gly) and two positively charged domains (Pro-Arg-Gly) at

85 }(Ac) wheel with glycolate ligands, {Pd84 }(Gly) , and the next in a magic number series for this cl

86 abolism (2-hydroxybutanoic acid, oxoproline, Gly, and Glu) were altered in UCP3 Tg mice across all tr

87 tively stable, whereas glucose oxidation and GLY are influenced by dietary factors.

88 rminal catalytic domain (CAT), a central Trp-Gly-Arg (WGR) domain and an N-terminal region (NTR).

89 ns of poly(Gly-Pro), poly(Gly-Ala), and poly(Gly-Arg) dipeptide repeat proteins, as well as TDP-43 pa

90 the highest sensitivity and selectivity Leu-Gly-Arg-Met-Gly-Leu-Pro-Gly-Lys was selected to construc

91 sp at position 177, Gln/Glu at position 180, Gly/Arg at position 239, and Pro/Ser at position 280.

92 al exchange of Gln/Glu at position 180 or by Gly/Arg at position 239.

93 Using glycine (Gly) as an example, we demonstrate a novel method to acc

94 minobutyric acid > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp.

95 Although Arg-Gly-Asp (RGD) integrin ligand and matrix softening confe

96 independently of IGF binding through an Arg-Gly-Asp (RGD) integrin-binding motif.

97 C3 harbors an Arg-Gly-Asp (RGD) motif, which is the major integrin-binding

98 migration by targeting integrins, using Arg-Gly-Asp (RGD) peptide-functionalized gold nanorods.

99 Cyclic peptides containing the Arg-Gly-Asp (RGD) sequence have been shown to specifically b

100 Peptides containing the Arg-Gly-Asp (RGD) sequence have high affinity for alphavbeta

101 ful intermediates for the preparation of Arg-Gly-Asp (RGD)-based cyclopentapeptides (cRGD) with nanom

102 We previously demonstrated that Arg-Gly-Asp (RGD)-containing ligand-mimetic inhibitors of in

103 th a higher affinity compared with other Arg-Gly-Asp binding integrins.

104 cription was effectively blocked by RGD (Arg-Gly-Asp) peptide and neutralizing alphavbeta3 antibodies

105 ocal stresses on the cell surface via an Arg-Gly-Asp-coated magnetic bead.

106 li serine O-acetyltransferase uses a similar Gly-Asp-Gly-Ile motif to form the "cysteine synthase" co

107 d lipid domains increased beta1-integrin-Arg-Gly-Asp-peptide affinity and valency, thus implicating L

108 elial cells, BA increased beta1-integrin-Arg-Gly-Asp-peptide affinity by 18% with a transition from s

109 is highly preferred for binding to conserved Gly:Asp:Asn residues.

110 rigin, we addressed internal dynamics of CAP-Gly assembled on polymeric microtubules, bound to end-bi

111 0), including a preference for Ser, Arg, and Gly at the +1 and a preference for Arg at the +7 positio

112 the GG motif constituted of two consecutive Gly at the C-terminus.

113 and two positively charged domains (Pro-Arg-Gly) at both N- and C-termini.

114 -Ser, -Val and the three achiral amino acids Gly, beta-Ala, and GABA).

115 Rates of EGP and GLY both at rest and during exercise were significantly

116 e traditional beta-turn motifs such as d-Pro-Gly, both the 2-Abz and d-Phe rings may be further funct

117 On the contrary, CAP-Gly bound to EB1 is significantly more rigid.

118 The consequences of replacing a Gly by Ser at each position in the required (Gly-Xaa-Yaa

119 Ga-P03034 ((68)Ga-DOTA-dPEG2-Lys-Arg-Pro-Hyp-Gly-Cha-Ser-Pro-Leu) in B1R-positive (B1R+) HEK293T::hB1

120 Strict L-chiral rejection through Gly-cisPro motif during chiral proofreading underlies th

121 tability and structural measures, such as NH(Gly)-CO(Asn-sc) distances.

122 ing infection, including the cleavage of Phe/Gly-containing nucleoporin proteins (Nups) within nuclea

123 I viral fusion proteins, including high Ala/Gly content, intermediate hydrophobicity, and few charge

124 02090 ((68)Ga-DOTA-dPEG2-Lys-Lys-Arg-Pro-Hyp-Gly-Cpg-Ser-D-Tic-Cpg) derived from 2 potent B1R antagon

125 rgo rearrangements of the N-terminal Asp-Phe-Gly (DFG) motif of the activation loop, with some, inclu

126 protocols for the preparation of various Xaa-Gly dipeptide surrogates in the form of Xaa-psi[triazole

127 CAP-Gly domain of dynactin, a microtubule-associated activat

128 e is due to low plus end affinity of the CAP-Gly domain-containing N-terminus and intramolecular inhi

129 lasmic linker protein 170 (CLIP170) is a CAP-Gly domain-containing protein that is associated with th

130 keleton-associated protein glycine-rich (CAP-Gly) domain of dynactin motor on polymeric microtubules,

131 In the tested conditions, the GLY environment was more effective than the HRGS system

132 f either Nup214 or Nup358, the two major Phe-Gly (FG) repeat nucleoporins localized on the cytoplasmi

133 the small hydrophobic peptide Z-d-Phe-l-Phe-Gly (FIP) was shown to block MeV infections and syncytiu

134 te mutation (FnIII9(R)-->(A)10), (iii) a two-Gly (FnIII9(2G)10) insertion, and (iv) a four-Gly (FNIII

135 ly (FnIII9(2G)10) insertion, and (iv) a four-Gly (FNIII9(4G)10) insertion in the interdomain linker r

136 The inhibitors carbobenzoxy (Z)-d-Phe-l-Phe-Gly (fusion inhibitor peptide [FIP]) and 4-nitro-2-pheny

137 endent on stretches of rare codons, Leu(UUA)-Gly(GGU)-Val(GUA).

138 work (MOF) based on the tripeptide Gly-l-His-Gly (GHG) for the enantioselective separation of metamph

139 omprising a formamidinylated, N-hydroxylated Gly-Gln dipeptide conjugated to 6'-amino-pseudouridine.

140 cids in all fractions were dominated by Ala, Gly, Glu and Ser.

141 in sequences revealed the presence of an Asp-Gly-Glu (DGE) alpha2beta1 integrin-binding motif in the

142 We identify a Lys-Gly-Glu (KGE) integrin-binding motif in the FVIIa protea

143 n-473 is positioned on a short loop (Asn-Gln-Gly-Glu-Pro) instead of an alpha-helix and forms hydroge

144 n which the residue preceding the C-terminal Gly-Gly (diGly) is replaced with a lysine (SUMO(KGG)).

145 irulence peptide 1 (vp1), a highly expressed Gly-Gly peptide-encoding gene in chinchilla middle ear e

146 The Arg-Gly-Gly repeats within the low-complexity region are req

147 N-unsubstituted alpha-amino acids, dipeptide Gly-Gly, and also benzylamine were used as the amine com

148 d phage-displayed peptide libraries Ser-[X]4-Gly-Gly-Gly, with Gly and Ser encoded using unique combi

149 which recognizes the pan-opioid sequence Tyr-Gly-Gly-Phe at the N terminus of most endogenous opioid

150 Among the small peptides 2-31, (H)Gly-Gly-Phe-Leu(OMe) (30) reduced prostaglandin producti

151 % MS SI restoration for the Z-Gly-Gly-Val and bradykinin peptides were 75-83% while %

152 s 0.85 [95% CI, 0.63 to 1.15] for Arg/Gly or Gly/Gly, P = .97).

153 ethanediyl)]dipyridine, en = ethylendiamine, gly = glycinate, and acac = acetylacetonate, have been s

154 e key amino acid substitutions (Trp --> Pro, Gly --> Ser and Arg --> Leu) are responsible for the evo

155 cluster consisting of six genes, gtf1, gtf2, gly, gtf3, dGT1 and galT2.

156 cluster consisting of six genes: gtf1, gtf2, gly, gtf3, dGT1, and galT2 Mature Fap1 glycan possesses

157 phenylalanine-glycine), and [Mn(II) + (l-Phe-Gly - H) + M](+) complex ions are used to determine coll

158 Carnosine and Gly-His were the best substrates for all UPF0586 ortholo

159 aniline-diglycolic acid-DPhe-Gln-Trp-Ala-Val-Gly-His-Leu-NHEt), showing excellent tumor localizing ef

160 rboxymethyl-piperidine-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 ((68)Ga-RM2) is a synthetic bombesin

161 rboxymethyl-piperidine-d-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 ((68)Ga-RM2) is a synthetic bombesin

162 arboxymethylpiperidine-d-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 (RM2, 1; DOTA:1,4,7,10-tetraazacyclo

163 04158 ((68)Ga-DOTA-dPEG2-Lys-Lys-Arg-Pro-Hyp-Gly-Igl-Ser-D-Igl-Oic) and Z02090 ((68)Ga-DOTA-dPEG2-Lys

164 died peptides of the sequence EGAAXAASS (X = Gly, Ile, Tyr, Trp) through comparison of molecular dyna

165 e O-acetyltransferase uses a similar Gly-Asp-Gly-Ile motif to form the "cysteine synthase" complex wi

166 am-positive bacteria lack C-terminal Gly-Tyr-Gly-Ile motifs, suggesting that they do not interact wit

167 diA-CT(EC536) inserts its C-terminal Gly-Tyr-Gly-Ile peptide tail into the active-site cleft of CysK

168 he presence of the proximal l-Ala instead of Gly in the common configuration of the peptide side chai

169 The replacement of one Gly in the essential repeating tripeptide sequence of th

170 The role of GalT2 and Gly in the Fap1 glycosylation is unknown.

171 An absolutely conserved Gly in the middle of the alpha1-helix of betaI helps mai

172 no acid residues in the P2 position, and for Gly in the P1 position, which is absolutely conserved in

173 ed fluorescence assay suitable for measuring Gly influx, and other fluorescence assays for leakage an

174 This organization of GABA and GLY inputs may be related to functional zones with diffe

175 in alpha3beta1 binding 17-fold, and the four-Gly insertion decreased binding 39-fold compared with Fn

176 haride), [l-Phe-Gly + M + H](+) (where l-Phe-Gly is l-phenylalanine-glycine), and [Mn(II) + (l-Phe-Gl

177 Gly is the only amino acid that has remained intolerant

178 unterpart in charging the mitochondrial tRNA(Gly) isoacceptor, which carries a defective TpsiC hairpi

179 anic framework (MOF) based on the tripeptide Gly-l-His-Gly (GHG) for the enantioselective separation

180 ment of the central hydrophobic residue with Gly (L83G) also conferred no ethidium resistance phenoty

181 - 1.1 mg kg(-1) min(-1) , P < 0.01; Exercise GLY: LCHF, 3.2 +/- 0.7 mg kg(-1) min(-1) , Mixed, 5.3 +/

182 sensitivity and selectivity Leu-Gly-Arg-Met-Gly-Leu-Pro-Gly-Lys was selected to construct calibratio

183 emonstrate abnormally elevated brain Glu and Gly levels in patients with first-episode psychosis by m

184 Significantly higher Glu and Gly levels were found in both the anterior cingulate cor

185 Glu and Gly levels were measured in vivo in the anterior cingula

186 Glu and Gly levels were positively correlated in patients.

187 uantify in vivo glutamate (Glu) and glycine (Gly) levels in patients with first-episode psychosis as

188 Ala, Asp, Ser, and Thr at high rates and for Gly, Lys, Phe, Tyr, and Val at moderate or low rates, re

189 and selectivity Leu-Gly-Arg-Met-Gly-Leu-Pro-Gly-Lys was selected to construct calibration curves.

190 Immunoglobulins to Gly m 4, Vig r 1 and Api g 1.01 were detected in <65% of

191 8 > Pru p 1 > Aln g 1 > Api g 1 > Act d 8 > Gly m 4.

192 ny dose level, sIgE/IgG4 against Bet v 1 and Gly m 4.

193 ed only in active group (Bet v 1: P = 0.054, Gly m 4: P = 0.037), and no relevant changes occurred fo

194 ine and M is a given monosaccharide), [l-Phe-Gly + M + H](+) (where l-Phe-Gly is l-phenylalanine-glyc

195 The high-affinity FXR agonist GW4064 blocks Gly-MCA action in the gut, and intestine-specific Fxr-nu

196 anistically, the metabolic improvements with Gly-MCA depend on reduced biosynthesis of intestinal-der

197 y, ceramide treatment reverses the action of Gly-MCA in high-fat diet-induced obese mice.

198 Gly-MCA is a selective high-affinity FXR inhibitor that

199 These data suggest that Gly-MCA may be a candidate for the treatment of metaboli

200 t of mice with glycine-beta-muricholic acid (Gly-MCA) inhibits FXR signalling exclusively in intestin

201 re unresponsive to the beneficial effects of Gly-MCA.

202 examined by measuring its inhibition of NMDA/Gly-mediated current through NMDAR ion channels in mouse

203 cosylation by adding a rhamnose residue, and Gly mediates the final glycosylation step by transferrin

204 cosylation by adding a rhamnose residue, and Gly mediates the final glycosylation step by transferrin

205 The consequent Gly-tRNA(Gly) 'misediting paradox' is resolved by EF-Tu in the ce

206 Since only subsets of Phe/Gly motifs, particularly those within Nup62, Nup98, and

207 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-

208 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly,

209 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N-Cl-Tyr-Ala, and

210 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly, N-Cl-Tyr-Ala, and

211 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-Ala a

212 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-Ala along with thei

213 N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-Ala were identified

214 t the fourth position (ligand 3: H-Dmt-d-Ala-Gly-NMePhe-Pro-Leu-Trp-NH-Bn(3',5'-(CF3)2)) displays bin

215 RS efficiently charged the cytoplasmic tRNAs(Gly) of C. elegans, the mitochondrial form was much more

216 ated three mutant forms (I14X; X = Val, Ala, Gly) of the enzyme that have increased active site flexi

217 rmyl-protected glycine as the ligand (Formyl-Gly-OH) was crucial for the development of this reaction

218 o the effects of the agonist d-Ala2-N-MePhe4-Gly-ol enkephalin (DAMGO).

219 ioid receptor agonist [D-Ala(2), NMe-Phe(4), Gly-ol(5)]-enkephalin produces paradoxical behavioural r

220 r the mu-selectivity of [D-Ala(2),N-MePhe(4),Gly-ol(5)]enkephalin (DAMGO)-related glycopeptides by al

221 Intra-PFC DAMGO (D-[Ala2,N-MePhe4, Gly-ol]-enkephalin; a mu-opioid agonist) and d-amphetami

222 analysis of residue-specific dynamics of CAP-Gly on time scales spanning nano- through milliseconds r

223 g/Arg vs 0.85 [95% CI, 0.63 to 1.15] for Arg/Gly or Gly/Gly, P = .97).

224 nyl)alanine at positions 92 and 96; Z = Val, Gly, or Asn at position 95)).

225 due in the small subunit with Ser, Val, Gln, Gly, or Asp, and we analyzed the effects of these mutati

226 ination compounds [Ru(en)(pdto)]Cl2 (1), [Ru(gly)(pdto)]Cl (2), and [Ru(acac)(pdto)]Cl (3), where pdt

227 ncorporated species included two dipeptides (Gly-Phe (2) and Phe-Gly (3)), as well as a thiolated dip

228 t the fourth position (ligand 5: H-Dmt-d-Ala-Gly-Phe(4-F)-Pro-Leu-Trp-NH-Bn(3',5'-(CF3)2)) exhibits b

229 plasma with ligands 3, 5, and 7 (H-Tyr-d-Ala-Gly-Phe(4-F)-Pro-Leu-Trp-NH-Bn(3',5'-(CF3)2)) showed tha

230 triple helix conformation and stabilisation (Gly, Pro, Hyp and Hyl), whilst the Lys content was great

231 degrading the neutrophil chemoattractant Pro-Gly-Pro (PGP) and rationalized that the failure of conve

232 we report that the matrikine acetylated Pro-Gly-Pro (PGP) stimulates vascular inflammation through a

233 ntained nuclear RNA foci, inclusions of poly(Gly-Pro), poly(Gly-Ala), and poly(Gly-Arg) dipeptide rep

234 To our knowledge, the peptides Gly-Pro-Ala-Val, Val-Cys, and Phe-Phe have not been prev

235 largely undetectable in the effluent unless Gly-Pro-Arg-Pro (GPRP) was added to block fibrin polymer

236 Binding was attenuated by tirofiban and Gly-Pro-Arg-Pro amide, confirming a role for fibrin in a

237 d inactivates the chemotactic tripeptide Pro-Gly-Pro.

238 antigens in four patients, glycine receptor (GLY-R) in 5 patients, N-methyl-d-aspartate receptor in 4

239 nine (Tyr-Ala), and phenylalanylglycine (Phe-Gly), reacted with sodium hypochlorite, and these reacti

240 he molecular pathways leading to enhanced PG/GLY reactivity are described, along with the most impact

241 the dynamics of the major amino acids, e.g., Gly, remained unaltered with respect to parity.

242 Mutation of Glu-87 to Ala or Gly rendered the protein constitutively active as a kina

243 trinsically disordered proteins, such as Phe-Gly repeat domains, alters drastically when they are con

244 zation and solid-state assays indicated that Gly replacements at four sites within the Fn-binding seq

245 Molecular dynamics simulations showed these Gly replacements interfered with the interaction of a co

246 In contrast, Gly replacements N-terminal to the GFPGER sequence, up t

247 Here, the effect of Gly replacements within and nearby the integrin binding

248 e RetGC1 binding site, insertion of an extra Gly residue between Ser-173 and Leu-174 as well as delet

249 ond and ligates protein-LPXT to the terminal Gly residue of the nascent cross-bridge of peptidoglycan

250 Replacement of Gly residues C-terminal to GFPGER did not affect integri

251 Gly to Ser mutations within the two Gly residues in the essential GFPGER sequence prevented

252 A linker encompassing six extra Gly residues relative to wild-type EmrE failed to give r

253 Peptides carrying multiple Pro and Gly (residues with lowest helical propensity) retain str

254 ntains an RRM domain at the N terminus and a Gly-rich domain at the C terminus.

255 s the editing activity of ORRM4, whereas the Gly-rich domain is required for its interaction with ORR

256 The N-terminal Gly-rich fragment of rSp0032 and the C-terminal His-rich

257 mbrane and coiled coil regions by a flexible Gly-rich linker.

258 (TTLL5) glutamylates RPGR(ORF15) in its Glu-Gly-rich repetitive region containing motifs homologous

259 in cleavage site between gp120 and gp41 with Gly-Ser linkers of various lengths.

260 mutation of tyrosine residues in Gly/Ser-Tyr-Gly/Ser motifs of the IDR reduced this effect, depending

261 Systematic mutation of tyrosine residues in Gly/Ser-Tyr-Gly/Ser motifs of the IDR reduced this effec

262 tics, a series of GLP-2 analogues containing Gly substitution at position 2, norleucine in position 1

263 ImAP41 contains an Asp-to-Gly substitution in helix III and our structures show th

264 glucose homeostasis (GLUT-4, G6PDH, Hk-2 and Gly-Syn-1).

265 In Staphylococcus aureus, a species-specific glyS T-box controls the supply of glycine for both ribos

266 of RPGR (RPGR(ORF15)), carrying multiple Glu-Gly tandem repeats and a C-terminal basic domain of unkn

267 We found that PB-Gly-Taxol bound the target protein beta-tubulin with bot

268 tagging") of LPXTG-containing substrates and Gly-terminated nucleophiles occurs in vitro as well as i

269 should be more compounds produced by PG and GLY than have been reported in e-cigarette aerosols to d

270 rmining factor; if it is turned away from HN(Gly), the chemostability increases.

271 solvents propylene glycol (PG) and glycerol (GLY), thereby affording unique product profiles as compa

272 tivation and coupling of C-terminal peptidyl Gly thioacids with the N-terminus of an unprotected pept

273 Whereas previous studies showed that Gly to Ser mutations within an integrin-binding site cau

274 Gly to Ser mutations within the two Gly residues in the

275 Constructs with Gly to Ser substitutions within and nearby the inserted

276 The Gly-to-Arg substitution at the 16 position (rs1042713) i

277 We critically examine the effect of Gly-to-d-Ala substitutions on protein stability using ex

278 null effect observed for the small subset of Gly-to-d-Ala substitutions which are not stabilizing.

279 n of glutamic acid decarboxylase (GAD)67 and GLY transporter 2 (T2) in axonal terminals to better und

280 ing in collagen peptides composed of Pro-Hyp-Gly triplet repeats, allowing for truncation to the smal

281 Moreover, DTD's activity on non-cognate Gly-tRNA(Ala) is conserved across all bacteria and eukar

282 architecture can efficiently edit mischarged Gly-tRNA(Ala) species four orders of magnitude more effi

283 The consequent Gly-tRNA(Gly) 'misediting paradox' is resolved by EF-Tu

284 polar mixture composed of Leu-Val, Leu-Tyr, Gly-Tyr, and Ala-Tyr dissolved in DMSO-d6/GL (8:2, v/v)

285 from Gram-positive bacteria lack C-terminal Gly-Tyr-Gly-Ile motifs, suggesting that they do not inte

286 EC536) CdiA-CT(EC536) inserts its C-terminal Gly-Tyr-Gly-Ile peptide tail into the active-site cleft

287 entified as Val-Glu-Leu-Tyr-Pro, Ala-Phe-Val-Gly-Tyr-Val-Leu-Pro and Glu-Lys-Ser-Tyr-Glu-Leu-Pro.

288 three model dipeptides, tyrosylglycine (Tyr-Gly), tyrosylalanine (Tyr-Ala), and phenylalanylglycine

289 the products derived from vaporizing PG and GLY under mild, single puff conditions.

290 s indicate that the structure adopted by CAP-Gly varies, particularly around its loop regions, permit

291 ceptor ligand, analogs H-Tyr-c[D-Lys-Xxx-Tyr-Gly] were synthesized and their biological activity was

292 mming included a higher rate of metabolizing Gly, which provides additional evidence that the metabol

293 displayed peptide libraries Ser-[X]4-Gly-Gly-Gly, with Gly and Ser encoded using unique combinations

294 the self-assembly of type I collagen via the Gly-X-Y motif, the molecular mechanism by which enamel m

295 ain, which is defined by the presence of the Gly-X-Y triplet repeats, is amongst the most versatile a

296 ir triple-helical structures and distinctive Gly-Xaa-Yaa repeating sequence, where Xaa is often proli

297 Gly by Ser at each position in the required (Gly-Xaa-Yaa)6 Fn-binding sequence are probed here, using

298 neral surface (regardless of the presence of Gly-zw) becomes greater than that of bulk phase.

299 med via adsorption of zwitter-ionic glycine (Gly-zw) onto the surface of sodium montmorillonite (Na-M

300 atic attraction between the -NH3(+) group of Gly-zw, and the negatively charged Na-MMT surface, provi