ライフサイエンスコーパス: Golgi cisternae

1 the structural organization and function of Golgi cisternae.

2 ed in understanding tubules that connect the Golgi cisternae.

3 cleate) from both the centrosome and the cis-Golgi cisternae.

4 SP-dependent membrane tethering of analogous Golgi cisternae.

5 se two GRASP proteins work together to stack Golgi cisternae.

6 cles were recruited to the region of nascent Golgi cisternae.

7 localized with Sec7-DsRed, a marker of trans-Golgi cisternae.

8 close proximity to ER exit sites and to cis Golgi cisternae.

9 rather than a direct role in the stacking of Golgi cisternae.

10 ype of secretory vesicles derived from trans-Golgi cisternae.

11 eticulum (ER)-derived membranes nucleate new Golgi cisternae.

12 all of the buds that lack ER also lack early Golgi cisternae.

13 ts in the inheritance of both early and late Golgi cisternae.

14 existing Golgi compartments to generate new Golgi cisternae.

15 hat GRASP65 is directly involved in stacking Golgi cisternae.

16 regulate assembly of COPI coat complexes on Golgi cisternae.

17 ickness and alignment with the other stacked Golgi cisternae.

18 ocalization, and in marked disruption of the Golgi cisternae.

19 nt (ERGIC), and ERGIC elements then generate Golgi cisternae.

20 y of SNARE proteins, Sed5p, present in early Golgi cisternae.

21 onation indicate that it is present in early Golgi cisternae.

22 lpha-factor and the accumulation of abnormal Golgi cisternae.

23 reticulum before being transported into the Golgi cisternae.

24 le in calcium homeostasis in the CGN and cis-Golgi cisternae.

25 n the p115-mediated docking of vesicles with Golgi cisternae [12].

26 proportional increase in the number of trans-Golgi cisternae, a switch to larger-sized secretory vesi

27 Margins of trans-Golgi cisternae accumulate the LM8 xylogalacturonan (XGA

28 down or in ARCL2 cells resulted in distended Golgi cisternae, accumulation of abnormal lysosomes and

29 tion of the golgin GMAP-210 causes a loss of Golgi cisternae and accumulation of numerous vesicles.

30 icles bud exclusively from medial- and trans-Golgi cisternae and are confined to the space around the

31 BP-80 protein is present in dilated ends of Golgi cisternae and in "prevacuoles," which are small va

32 Coat protein I (COPI) vesicles arise from Golgi cisternae and mediate the recycling of proteins fr

33 es are segregated from each other within the Golgi cisternae and packaged into separate vesicles.

34 al endocytosis and retrograde transport into Golgi cisternae and perhaps ER.

35 infected cells, F13L-GFP was associated with Golgi cisternae and post-Golgi vesicles containing the L

36 s in transit resulted in condensation of the Golgi cisternae and stacks.

37 nalysis revealed that Cdc42 is active at all Golgi cisternae and that this activity is controlled by

38 ctron microscopy, CALNUC is localized to cis-Golgi cisternae and the cis-Golgi network (CGN).

39 amily has been implicated in the stacking of Golgi cisternae and the regulation of Golgi disassembly/

40 ed with the plasma membrane and occasionally Golgi cisternae and tubulovesicles.

41 were continuously concentrated over stacked Golgi cisternae and tubulovesicular Golgi structures sim

42 level, Golgi fragments showed swollen distal Golgi cisternae and vesicular structures.

43 analogous to early (RER and ERGIC), middle (Golgi cisternae), and late (TGN) secretory pathway compa

44 d secretory vesicles that bud from the trans-Golgi cisternae, and an increase in osmium staining of t

45 e contacts with mitochondria, multiple trans Golgi cisternae, and compartments of the endo-lysosomal

46 Protein I)-coated vesicles and buds, but not Golgi cisternae, and it specifically activates Rab1.

47 34 expressed in HeLa cells was restricted to Golgi cisternae, and its membrane association was sensit

48 ulum and the Golgi complex, between adjacent Golgi cisternae, and possibly in the endocytic pathway.

49 During telophase, Golgi cisternae are regenerated and stacked from a heter

50 and transport continue-even when individual Golgi cisternae are separated and "land-locked" between

51 Before entering mitosis, the stacks of the Golgi cisternae are separated from each other, and inhib

52 localizes with RabE(RAB11), arriving at late Golgi cisternae as they dissipate into exocytic carriers

53 bute to stacking and lateral interactions of Golgi cisternae as well as help it function as a vesicle

54 In mammalian cells, flat Golgi cisternae closely arrange together to form stacks.

55 ipogenesis and is primarily localized to the Golgi cisternae distinct from the trans-Golgi network (T

56 t mediate both formation and stacking of the Golgi cisternae during post-mitotic reassembly.

57 This juxtaposition may indicate that Golgi cisternae form at tER sites.

58 are most readily explained by assuming that Golgi cisternae form at the cis face of the stack, progr

59 an NSF function during cell-free assembly of Golgi cisternae from mitotic Golgi fragments revealed th

60 s essential for the p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments, a process

61 mammalian cells.The different composition of Golgi cisternae gave rise to two different models for in

62 ter incubation demonstrated that the stacked Golgi cisternae generated a heterogeneous population of

63 sicle trafficking between the cis and medial Golgi cisternae has been used previously to identify sev

64 d that CS2 antiserum stains medial and trans-Golgi cisternae in all cell types investigated.

65 EM data showed a dilation of Golgi cisternae in cells expressing the M2 ion channel p

66 the cell, and PtdIns4P is elevated on medial Golgi cisternae in cells lacking Vps74 or Sac1, suggesti

67 Although the dilation of some Golgi cisternae in Cog5-deficient cells resembled that o

68 s coexpressed, but was largely restricted to Golgi cisternae in the absence of F13L-GFP or when the F

69 been shown to play a role in stacking of the Golgi cisternae in vitro.

70 Ypt/Rab family, Ypt1 and Ypt31, to specific Golgi cisternae interferes with addressing this question

71 The stacking of Golgi cisternae involves GRASP65 and GRASP55.

72 This behavior of late Golgi cisternae is consistent with the cisternal maturat

73 Golgi has been explained by the movement of Golgi cisternae, known as cisternal maturation.

74 importance of retrieval-based targeting, few Golgi cisternae-localized proteins have been demonstrate

75 f eicosanoid products, while the location in Golgi cisternae may also reflect its action as a secrete

76 lized to vesicular tubular complexes and cis-Golgi cisternae, mostly in brain, atlastin-2 and -3 are

77 f Ena increases the number of cis- and trans-Golgi cisternae per cell, and Ena overexpression also re

78 APM1 localizes at the margins of Golgi cisternae, plasma membrane, select multivesicular

79 Restacking of the newly formed Golgi cisternae requires dephosphorylation of Golgi stac

80 We are prone to thinking by analogy-Golgi cisternae stack like pancakes, red blood cells loo

81 elevates C1P steady-state levels and alters Golgi cisternae stack morphology.

82 ow three types of direct connections between Golgi cisternae that are normally distinct from one anot

83 ps74 is a sensor of PtdIns4P level on medial Golgi cisternae that directs Sac1-mediated dephosphospho

84 ese tomograms revealed structures within the Golgi cisternae that have not been seen before.

85 Staples and soluble aggregates placed in cis-Golgi cisternae therefore have different fates.

86 mine the narrow central spacing of the trans-Golgi cisternae through zipper-like interactions, thereb

87 anes have been implicated in the adhesion of Golgi cisternae to each other to form their characterist

88 SP domain and mediate homotypic tethering of Golgi cisternae to form extended Golgi ribbons.

89 stacking of Golgi by the ectopic adhesion of Golgi cisternae to mitochondria.

90 pergillus nidulans hyphae, we show that late Golgi cisternae undergo changes in composition to gradua

91 The pericentriolar stacks of Golgi cisternae undergo extensive reorganization during

92 and have been implicated in the stacking of Golgi cisternae, vesicle tethering, and mitotic progress

93 ate that GRASP55 and GRASP65 stack mammalian Golgi cisternae via a common mechanism.

94 GRASP65 links cis-Golgi cisternae via a homotypic, N-terminal PDZ interact

95 rane protein complex localized on cis/medial Golgi cisternae where it may participate in tethering in

96 t intermediate production and consumption by Golgi cisternae, with only a minor contribution of pre-e

97 nsferase was mapped to the medial- and trans-Golgi cisternae, with some being present in the TGN.

98 hondria to invade the stack and even replace Golgi cisternae within a few hours.