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1 zed to mitochondria with a long t (1/2) (>36 h).
2 that tested negative for both viruses (74.1 h).
3 d in ADAM10-cleaved PrP and heparan sulfate (HS).
4 te clearance to levels <=2.5 mmol/L within 4 h.
5 en (100 kPa), which remained stable up to 22 h.
6 B opening, followed by BBB closure within 24 h.
7 germination phases: before 14 h and after 48 h.
8 observed in the lung and heart for up to 24 h.
9 oat through sprouting at 18 degrees C for 96 h.
10 ere observed in UCH-L1, Iba-1 or IL-6 over 6 h.
11 tomatal response can be retriggered within 6 h.
12 plastic, and nitrile for half-life 2.3-17.9 h.
13 ors are established aetiological factors for HS.
14 t sustained physiologic hyperglycemia for 72 h 1) increases absolute insulin secretion but impairs be
15 y large turnover frequency (TOF) up to 12500 h(-1) at -0.95 V versus the reversible hydrogen electrod
16 matically, achieving 103.21 mmol g(cat) (-1) h(-1) with near-unity selectivity for CO generation and
18 CVID-associated immune dysregulation is a T(H)1-mediated inflammatory process driven by the IFN-gamm
19 make dysprosiacarboranes, namely [(C(2) B(9) H(11) )(2) Ln(THF)(2) ][Na(THF)(5) ] (Ln=Dy, 1Dy) and [(
20 ensed phases unambiguously assigned using (1)H, (13)C, (15)N, (29)Si, and (1)H DOSY NMR as well as X-
22 bal transcriptome reversion and normalized T(H)17 cell/IL23 signaling, whereas dupilumab led to a str
24 pressed the development of IL-17-producing T(H)17 cells but increased the generation of those produci
28 -733-dps is stable and shows no loss of C(2) H(2) adsorption capacity following multiple adsorption-d
29 ing of the TiO(2) support during heterolytic H(2) adsorption; evidence for this phenomenon was observ
30 7) for the reactions of diphenyl ether under H(2) and D(2) atmosphere and a positive dependence of th
31 yzing benzene/pyridine solutions of 4a under H(2) and D(2) atmospheres (150 psi), which leads to the
32 2) may be readily separated and sequestered, H(2) and/or O(2) may be used to generate electric power
35 ere and a positive dependence of the rate on H(2) chemical potential in decalin indicate that additio
36 ty holding a single metal, to a binucleating H(2) ema(2-) with bridging sulfurs and carboxamide oxyge
40 that hole-driven scission of the O-H bond in H(2) O is a critical, limiting step in plasmonic photosy
41 of glutathione (GSH) and hydrogen peroxide (H(2) O(2) ) with high specificity on a basis of domino r
42 e development of a unique hydrogen peroxide (H(2) O(2) )-sensing motif and its capacity for providing
43 hat H(2) O(2) upregulated ENaC activity, and H(2) O(2) production was reduced in both the renal corte
45 ly shorter lag times and faster rates of net H(2) oxidation and dark carbon dioxide (CO(2)) fixation
46 produced up to two orders of magnitude less H(2) than their modern counterparts, consistent with Fe-
54 signaling cascade, which leads to increased H(2)O(2) and Ca(2+) levels and F-actin reorganization, b
55 tibody (mAb) that inhibited AQP3-facilitated H(2)O(2) and glycerol transport, and prevented liver inj
57 pecies is used as a strategy to avoid adding H(2)O(2) in the solution during the detection of phenoli
59 membrane side and subsequently terminated by H(2)O(2) oxidation on the anodic membrane side, is cruci
63 al function is maintained in the presence of H(2)S in sulfide spring P. mexicana but not ancestral li
64 ibitor DL-propargylglycine demonstrated that H(2)S is the effector molecule regulating Mtb survival i
65 rophile, Pseudomonas, Enterobacteriaceae and H(2)S producing bacterial counts were obtained in PEF-1
66 d WT and CSE(-/-) macrophages using the slow H(2)S releaser GYY3147 and the CSE inhibitor DL-propargy
68 we summarize recent work that suggests that H(2)S/RSS impacts bacterial survival in infected cells a
69 deficiency could induce higher numbers of T(H) 2 cells in the lung, but those cells release decrease
73 ype 2 innate lymphoid cell activation, and T(h)2 cell differentiation were found in gut mucosa of mic
75 th the longest alkoxy chains examined (OC(12)H(25)), which, although shown by in situ X-ray diffracti
76 nodominant TMEV peptide VP2(121-130) Loss of H-2D(b) on CD11c(+) APCs mitigates the CD8 T cell respon
80 Me) LZn(S)] (2) ((Me) L={(2,6-(i) Pr(2) C(6) H(3) )NC(Me)}(2) CH), was isolated via reaction of [(Me)
81 I) alkynyl [Cu(II)]-C=CAr (Ar = 2,6-Cl(2)C(6)H(3)) forms upon reaction of the alkyne H-C=CAr with the
83 [Na(THF)(5) ] (Ln=Dy, 1Dy) and [(THF)(3) (mu-H)(3) Li](2) [{eta(5) -C(6) H(4) (CH(2) )(2) C(2) B(9) H
84 rmulated as [Cu(81)(PhS)(46)((t)BuNH(2))(10)(H)(32)](3+) (Cu(81)), was successfully synthesized and f
85 )(2) C(2) B(9) H(9) }Dy{eta(2) :eta(5) -C(6) H(4) (CH(2) )(2) C(2) B(9) H(9) }(2) Li] 3Dy and show th
86 nd [(THF)(3) (mu-H)(3) Li](2) [{eta(5) -C(6) H(4) (CH(2) )(2) C(2) B(9) H(9) }Dy{eta(2) :eta(5) -C(6)
87 ation of C(2)H(4) from a binary C(2)H(6)/C(2)H(4) and ternary C(2)H(4)/C(2)H(2)/C(2)H(6) mixture.
88 (MOF) for highly efficient separation of C(2)H(4) from a binary C(2)H(6)/C(2)H(4) and ternary C(2)H(4
89 lexes, made by the reaction of Rh(eta(2)-C(2)H(4))(2)(acetylacetonate) with the support and anchored
90 efinated through the isolated (N, O)(Ph, C(6)H(4), C) oxaphosphetanes (Channel A), whereas MoBA compo
91 pounds decomposed faster via the isomer (C(6)H(4), O)(C, N, Ph) formed by P-stereomutation involving
93 the subsequent adsorption of thiophene (C(4)H(4)S) depends strongly on the location on the edge of M
94 g our proposed technique was found to be 105 h, 48 h, and 17 h respectively, highly correlated with T
97 ent separation of C(2)H(4) from a binary C(2)H(6)/C(2)H(4) and ternary C(2)H(4)/C(2)H(2)/C(2)H(6) mix
99 Ss) with a molecular weight (MW) of 212 (C(5)H(8)SO(7)), which are abundantly present in both ambient
100 (2) :eta(5) -C(6) H(4) (CH(2) )(2) C(2) B(9) H(9) }(2) Li] 3Dy and show that dicarbollide ligands imp
101 2) [{eta(5) -C(6) H(4) (CH(2) )(2) C(2) B(9) H(9) }Dy{eta(2) :eta(5) -C(6) H(4) (CH(2) )(2) C(2) B(9)
102 ne at 359.0 K was calculated to be Delta(vap)H = 91.27 +/- 0.28 kJ/mol compared to Delta(vap)H(corr)
106 Analogous photoredox catalysis enables C-H activation and H/D exchange in a number of additional
108 -metal-catalyzed, template-directed remote C-H activation reactions of alcohols, carboxylic acids, su
109 and urine samples were collected for up to 4 h after injection to assess metabolite-corrected radioac
110 d into the jugular-vein catheter before or 6 h after MRSA inoculation, while an equal volume of salin
111 ore pPCI or complete ST-segment resolution 1 h after pPCI in patients presenting with ST-segment-elev
112 The median area under the curve (AUC0-24 h) after day 7 and 14 were compared as well as the varia
113 eparate, we compared (13)CO-detect versus (1)H(alpha)-detect experiments, showing that significant se
115 unts, that were characterized by means of (1)H and (13)C NMR spectrometry as well as single-crystal X
116 ia sample of each reaction (as opposed to 24 h and 50 muL, respectively, with the conventional broth
119 30 mg/m(2) administered intravenously over 2 h and oral capecitabine 1000 mg/m(2) twice daily on days
120 ese devices with the optimal flow rate (1 mL/h) and channel length (2 cm) were demonstrated to test t
121 flat dose administered intravenously over 2 h), and fluorouracil bolus 400 mg/m(2) administered intr
122 proposed technique was found to be 105 h, 48 h, and 17 h respectively, highly correlated with TVB-N,
123 erture size returns to control size within 3 h, and the systemic stomatal response can be retriggered
125 n that genetic therapies currently tested in HD are primarily expected to target the cortex, understa
129 lactalbumin (alpha-La), was achieved after 4 h, at E/S ratios of 1/150 U/mg, regardless the initial p
133 lly relied on precious-metal catalysts for C-H bond cleavage and, as a result, display high selectivi
134 ts, which indicated that the gamma-C(sp(3) )-H bond cleavage is the rate-limiting step during the rea
135 inference that hole-driven scission of the O-H bond in H(2) O is a critical, limiting step in plasmon
137 lizes multiple noncovalent interactions like H-bonding, solvent bonding, S-H...pai, C-H...pai, pai-pa
139 volving the intramolecular coupling of two C-H bonds on gem-dialkyl groups has remained an elusive tr
144 ive functionalizations of carbon-hydrogen (C-H) bonds represent a promising pathway toward this goal.
145 r-protic solvent combinations to disrupt the H-bonds and hydrophobic interactions holding together th
146 These proteins contain a continuous chain of H-bonds that impart stability, causing difficulty in dig
149 e presented that reveal two mechanisms for C-H borylation, (i) electrophilic aromatic substitution (p
150 ~50 kb on both sides of the lesion within 1 h; but the kinetics and distribution of modification aro
151 d a dramatic increase of the coercive field (H(c) ) by more than 150% with an applied strain of 0.32%
154 )C(6)H(3)) forms upon reaction of the alkyne H-C=CAr with the copper(II) tert-butoxide complex [Cu(II
158 stimulated a ~46% increase in MyoPS rates (%/h) compared with 0 g PRO and was sufficient to maximize
159 91.27 +/- 0.28 kJ/mol compared to Delta(vap)H(corr) = 91.44 kJ/mol for the reference correlation.
160 xhibits 16-fold lower binding affinity than (Hs)CRM1 toward PKI-NES and significant differences in af
161 tate and transient kinetic studies involving H/D and (13)C/(12)C exchange, coupled with operando infr
162 toredox catalysis enables C-H activation and H/D exchange in a number of additional substrates with f
164 , UV-irradiation of ubiquitin did not induce H/D scrambling in the nonfragmented precursor ion popula
166 arkedly increased but arrhythmic over the 24-h day, whereas levels of the other incretin, glucose-dep
168 e-1 knockout) cells, reduced 3-O-S levels of HS diminished both cell surface binding and internalizat
169 d animal models of hidradenitis suppurativa (HS) display issues with fidelity and validity to human d
170 r doping thus offers a pathway for efficient H doping in green solvent-processed metal oxide films an
173 CFU in either 25 g of ground turkey with a 7 h enrichment or 100 g of powdered infant formula with a
175 d stimulate non- HCO3- transporters (e.g. Na-H exchangers) by accelerating CO(2) / HCO3- -mediated bu
177 a indicate that multiple members of the CslF/H family fulfil important functions during grain develop
183 nd stereoselective distal allylic/benzylic C-H functionalization of allyl and benzyl silyl ethers was
185 atalyst system to promote a para-selective C-H functionalization reaction from benzylic electrophiles
186 chieving highly regio- and stereoselective C-H functionalization reactions using a newly developed Rh
187 cals have long been known to enable remote C-H functionalization via 1,5-hydrogen atom abstraction.
188 odel, we altered the structure of osteoblast HS genetically to make it incapable of binding to OPG.
190 volution of H. sapiens in Africa and whether H. heidelbergensis/H. rhodesiensis was a direct ancestor
193 d intravenously over 5 min, followed by a 46 h infusion of fluorouracil 2400 mg/m(2) repeated every 2
194 The first example of enantioselective S-H insertion reactions of sulfoxonium ylides is reported.
196 s of a significant kinetic isotope effect (k(H) /k(D) =5.7) for the reactions of diphenyl ether under
198 85 mg/m(2) administered intravenously over 2 h, l-folinic acid (175 mg flat dose administered intrave
199 ated, although a predicted helix-loop-helix (H-L-H) was suggested to form pores by virtue of its simi
200 utilisation of NADH-dependent enzymes for (2)H-labelling is not straightforward, owing to difficultie
201 PSC were associated with an increase of MI 6 h later by 3.27% [95% confidence interval (CI): 0.27, 6.
204 ective and chemoselective oxidative C(sp(3))-H methylation method that is compatible with late-stage
205 Using an HD mouse striatal cell model and HD mouse organotypic brain slices we found that D(1)R-in
207 MD) and showed the feasibility of MRI and (1)H MR spectroscopy to track disease progression over a wi
208 al ageing in these brain regions using 7T (1)H-MRS and findings indicate that glia-related metabolite
212 haloperidol dose escalation at 2 mg every 4 h, neuroleptic rotation with chlorpromazine at 25 mg eve
219 us spans five US cities and consists of 19.8 h of audio matched on the age and gender of the speaker.
222 The study enrolled TIA patients within 72 h of onset from the prospective TIA database of the Firs
224 ogether with a number of previously prepared HS oligosaccharides, were printed as a glycan microarray
225 Patients with Parkinson's disease who had 2 h or more of off time per day with predictable morning o
226 flat dose administered intravenously over 2 h) or d,l-folinic acid (350 mg flat dose administered in
227 EACS randomized 1:1 to very early (within 12 h) or standard (48 to 72 h) invasive coronary angiograph
228 otation with chlorpromazine at 25 mg every 4 h, or combined haloperidol at 1 mg and chlorpromazine at
229 RA) that specific microbiota members show 24-h oscillations in their relative abundance and identifie
230 cal parameters to be calibrated at various S(h) over its range of variation, but such calibrations ar
231 d product chemoselectivity make asymmetric C-H oxidation a generally unsolved problem for nonenzymati
232 ghts key advances in scalable biocatalytic C-H oxyfunctionalization reactions developed within the pa
234 me for (177)Lu-DOTATATE was approximately 72 h p.i., whereas 48 h p.i. was better for (177)Lu-PSMA.
236 and serum aldosterone were 6.8 vs. 5.5 ng/mL/h (p = 0.002) and 654 vs. 473 pg/mL (p = 0.01), respecti
237 LOS was observed for patients with EV (51.6 h; P < 0.001) and PeV (66.3 h; P = 0.048) compared to pa
238 ts with EV (51.6 h; P < 0.001) and PeV (66.3 h; P = 0.048) compared to patients that tested negative
240 eractions like H-bonding, solvent bonding, S-H...pai, C-H...pai, pai-pai stacking, charge-transfer co
241 ike H-bonding, solvent bonding, S-H...pai, C-H...pai, pai-pai stacking, charge-transfer complexation,
243 brain tissues of unaffected individuals and HD patients, supporting the lack of deficit in mitochond
246 ear-old, previously healthy male presented 6 h post apparently uncomplicated colonoscopic polypectomy
249 al and human studies, GFAP, was highest at 6 h post-injury, while no substantial changes were observe
250 se of APOBEC3G with a half-life of roughly 6 h postinfection, demonstrating that Vif can concurrently
255 st 40 years ago when one of the authors (K.J.H.) published an organized system to quantify the accura
256 tudy is the longest prospective cohort of an H pylori eradication trial in a Hispanic population.
261 functional groups, providing a variety of N-H pyrroles in good yields and with high regioselectivity
262 n to phenocopy the PYCR1 knockdown in MCF10A H-RAS(V12) breast cancer cells by inhibiting de novo pro
264 echnique was found to be 105 h, 48 h, and 17 h respectively, highly correlated with TVB-N, TVC, pH an
267 adine-an open channel blocker of HCNs-for 24 h resulted in a dose-dependent higher HRV and lower hear
268 eurons, performed at different times over 24 h, revealed significant changes only for RNA-binding mot
269 ens in Africa and whether H. heidelbergensis/H. rhodesiensis was a direct ancestor of our species(13,
270 Sequencing (SIMMS(2)) method in which intact HS saccharides are dissociated in an ion mobility mass s
271 her questions about the mode of evolution of H. sapiens in Africa and whether H. heidelbergensis/H. r
273 he acetal unit considerably outpaces any 1,5-H shift and instead activates 1,5-methoxy migration, giv
274 el addition/intramolecular cyclization/[1,5]-H shift/cleavage of CS(2)/aromatization/nucleophilic acy
275 d antisepsis was remarkably reduced after 25 h shifts (predicted probability 99.4% vs 78.8%), whereas
277 action gas chromatography-mass spectrometry (HS-SPME-GC-MS) method for the quantification of 3-monoch
279 ng us to determine how heparanase recognizes HS substrate and selects a favorable cleavage site.
280 ish were subjected to one of three acute (24 h) temperature treatments: cold stress (18 degrees C), h
281 ithin the first day postinfection, but by 48 h the viral populations were dominated by fewer than thr
283 sanguineous, LVR solution in acute models of HS through mechanisms targeting cell swelling-induced mi
285 tential in decalin indicate that addition of H to the aromatic ring is involved in the rate-limiting
286 id solutions containing hydroxyethyl starch (HES) to correct for intravascular deficits in high-risk
291 simple colorimetric reactions in only 4.5-6 h using only 3 muL of bacteria sample of each reaction (
292 tolerated, although early vomiting (within 1 h) was more frequent after dihydroartemisinin-piperaquin
293 , although a predicted helix-loop-helix (H-L-H) was suggested to form pores by virtue of its similari
294 nucleophilic substitution of hydrogen (S(N)(H)) was first applied for the direct modification of non
295 previously found to be effective in treating HS, was evaluated using a subcutaneous formulation in pa