ライフサイエンスコーパス: H1 receptor

1 action (e.g., muscarinic M2 or M3, histamine H1 receptors).

2 e I collagen synthesis via the activation of H1 receptor.

3 ession is dependent on the activation of the H1 receptor.

4 set of these neurons expressed the histamine H1 receptor.

5 of 9.7, consistent with that expected for an H1 receptor.

6 me histamine receptor subtype, the histamine H1 receptor.

7 stamine exerted its effect by activating the H1 receptor.

8 centration evoked by activation of histamine H1 receptors.

9 abolished in mice with deletion of histamine H1 receptors.

10 pharmacology and interaction with histamine H1 -receptors.

11 ains an NO component but does not contain an H1 receptor activation component at the doses tested.

12 ease from human subcutaneous fibroblasts via H1 receptor activation.

13 of active vasodilatation can be explained by H1 receptor activation.

14 duced effects were mimicked by the histamine H1 receptor agonist 2-(2-aminoethyl) thiazole dihydrochl

15 gher doses of histamine were mimicked by the H1 receptor agonist alpha-2-(2-aminoethyl)pyridine (AEP)

16 Rupatadine has dual affinity for histamine H1 -receptors and PAF receptors.

17 es Egr-1 expression in primary HAECs via the H1 receptor and the PKCdelta-dependent ERK activation pa

18 One-week treatment with a histamine H1 receptor antagonist (H1RA) ameliorated the glucose in

19 Furthermore, administering either an H1 receptor antagonist (pyrilamine) or an H2 receptor an

20 of cycling at 60% on randomized control and H1 receptor antagonist days (540 mg oral fexofenadine hy

21 P-selectin upregulation was inhibited by the H1 receptor antagonist diphenhydramine, whereas the H2 r

22 Thus, ingestion of an H1 receptor antagonist markedly reduces vasodilatation a

23 lower concentrations of histamine, while the H1 receptor antagonist mepyramine (3 nM) blocked those o

24 The H1 receptor antagonist pyrilamine (10 microM) blocked ac

25 Noteworthy, the H1 receptor antagonist pyrilamine disrupted IA memory re

26 The histamine H1 receptor antagonist terfenadine prevented scratching

27 Loratadine, a clinically used histamine H1 receptor antagonist, was identified as a selective in

28 ce P combined with 500 microm pyrilamine, an H1 receptor antagonist.

29 been observed with the selective histamine1 (H1) receptor antagonist drug astemizole, a widely prescr

30 ,L was not mediated via effects on histamine H1 receptors, because 1 mumol/L triprolidine, a more sel

31 mine (100 microM) and caffeine (8 mM) during H1 receptor blockade activated ICl(Ca), but not ICat.

32 s intracellular calcium release, mediated by H1 receptors coupling to Gq/G11 proteins.

33 Thus, histamine acts centrally, via H1 receptors, during parturition and may have an excitat

34 rating concentrations to cause uncoupling of H1 receptors from phospholipase C.

35 ith high ligand efficiency for the histamine H1 receptor (H1R) was used to design derivatives to inve

36 CD4+ T-cells from histamine H1 receptor (H1R)-deficient (H1RKO) mice produce signifi

37 The results show that HA acting through H1 receptors (H1R) depolarizes these neurons.

38 nistration increased expression of histamine H1 receptor (HIR) and histidine decarboxylase (HDC) mRNA

39 rward genetic approach, we identified the HA H1 receptor (Hrh1/H1R) as the gene in mice that controls

40 esponse to histamine acting on the histamine H1 receptor in C-fiber nociceptive neurons.

41 uced calcium responses through the histamine H1 receptor in cultured sensory neurons.

42 nfirmed the expression of Galphaq/11-coupled H1 receptors in BCECs.

43 ontribute to postexercise vasodilatation via H1 receptors in the peripheral vasculature.

44 H1-receptor inverse agonists are used effectively for tr

45 of VWF and targeting FURIN and the histamine H1 receptor, known regulators of VWF processing and secr

46 T labeled sites is very similar to histamine H1 receptors labeled with [3H]-mepyramine.

47 These data suggest H1 receptor-mediated vasodilatation contributes to poste

48 o determine the potential contribution of an H1 receptor-mediated vasodilatation to postexercise hypo

49 Histamine (0.1-100 microM) caused an H1 receptor-mediated, dose-dependent depolarization of f

50 urons showed colocalization of expression of H1 receptor mRNA with estrogen receptor (ER)-alpha mRNA

51 ctivation of guanylate cyclase-cGMP to which H1 receptors often are linked .

52 Histamine H1 receptor systems have been shown in animal studies to

53 PATs represent a novel class of ligands for H1 receptors that can modulate tyrosine hydroxylase acti

54 in a population of GABAergic neurons, while H1 receptors were expressed in non-GABAergic cells.

55 , muscarinic acetylcholine M3, and histamine H1 receptors, while demonstrating no direct effect on Gq