コーパス検索結果 (left1)
  通し番号をクリックするとPubMedの該当ページを表示します
  
   1                                              HA and M2 are strongly coclustered in the plasma membran
     2                                              HA degradation requires either ERManI enzymatic activity
     3                                              HA digestion in wild type NSC cultures or in the SGZ ind
     4                                              HA dose-dependently inhibited TLR2-induced TNF-alpha pro
     5                                              HA is known to swell, fitting a linear elastic model wit
     6                                              HA is synthesized by NSCs and increases in the SGZ with 
     7                                              HA polymers are rationally designed from relatively low-
     8                                              HA was determined by a competition between the coating H
     9  at residues 156, 158, 189, and 193 of MN/10 HA to those in BJ/92 switched the MN/10 antigenic phenot
  
  
  
    13 on The highly concentrated nHA-HC paste (48% HA content) formed oversized particle agglomerates which
    14 ophilia A (AHA) and congenital hemophilia A (HA) are primarily directed to the A2 and C2 domains.    
    15 ixtures (200 mmol/L) high in either acetate (HA), propionate (HP), butyrate (HB) or placebo (PLA) wer
    16  changing, for instance, the pKa of the acid HA versus the concentration or partial pressure of a rea
  
  
  
    20 ime-dependent deposition of hyaluronic acid (HA) and increased expression of markers for alternative 
    21 ing pathological amounts of hyaluronic acid (HA) or chondroitin sulfate (CS) did not directly increas
    22 gional interactions between hyaluronic acid (HA), collagen and the spatial origins of mechanical stre
    23 bolism and the signaling of hyaluronic acid (HA), the major component of the extracellular matrix (EC
    24 on [D-dimer], and fibrosis (hyaluronic acid [HA]) were measured at baseline and through 96 weeks of A
  
  
    27 particles loaded with hydroxycinnamic acids (HA-NCs) have diameter of 224-253nm, encapsulation effici
    28   TOP-PCR adopts homogeneous "half adaptor" (HA), generated by annealing P oligo (carrying a phosphat
  
    30 ood supply to bile duct and lack of adequate HA flow is thought to be a risk factor for biliary compl
  
    32  H3N2 strains, the acute Ab response against HA exhibited an inherent bias toward lambda L chain usag
    33 othelial barrier-associated protein, altered HA production, and induced abnormal urothelial different
    34 18 days of exposure to 3454 m high altitude (HA) without drug intervention (control, CONT) as well as
  
  
  
  
    39 t with this, in wild-type embryos, HYAL2 and HA were readily detected, and HA levels decreased with a
  
  
    42 aman bands associated with the scaffolds and HA with the spatial offset depended on the depth at whic
    43 lucidate the differences in trogocytosis and HA formation mediated by anti-CD20 mAbs RTX and GA101, a
    44 antly increased accumulation of versican and HA, especially in the perivascular and peribronchial reg
  
  
    47 ricted, leukemia-associated minor H antigen, HA-1; (2) a CD8 coreceptor to promote function of the cl
  
  
    50 e effect of lower measured hepatic arterial (HA) flow (<400 mL/min) on biliary complications and graf
    51 that, in several mouse tumour models such as HA-expressing 4T1 mammary carcinoma cells, OVA-expressin
    52  NSC proliferation, and CD44-null as well as HA-disrupted wild type NSCs demonstrate delayed neuronal
  
  
  
    56 ation of both Eley-Rideal (ER) and hot atom (HA) mechanisms when H impinges on adsorbed CO2, and we s
  
    58 riable and no significant difference between HA and FA was found for major chemical groups, that is, 
    59  WTI and is promoted by a cross-talk between HA, CD73/adenosine signaling, and other profibrotic medi
  
  
  
  
  
    65 and microcomputed tomography to characterize HA in mouse models of advanced breast cancer in relevant
    66 rrets with viral vectors expressing chimeric HA, aimed at boosting Ab reactivity against the HA stem 
  
  
    69 ike particle (VLP) vaccines expressing COBRA HA proteins elicited antibodies with hemagglutination in
    70  characterization of 17 prototype H3N2 COBRA HA proteins were screened in mice and ferrets for the el
  
    72 s with COBRA HA based viruses or using COBRA HA based vaccines to boost preexisting antibodies induce
    73 ies induced by wild-type H1N1 viruses, COBRA HA antigens elicited sera with the broadest HAI reactivi
    74    Overall, priming naive ferrets with COBRA HA based viruses or using COBRA HA based vaccines to boo
    75 , while the stunting of fusion by deacylated HA acting in isolation may be balanced by other viral pr
  
    77 porphyrins in DMF as an example, decreasing [HA] 10-fold lowers etaeff by 59 mV and decreases the TOF
  
    79 RA technology was effectively used to design HA immunogens that elicited antibodies that neutralized 
    80 designed trimers can both capture and detect HA in a paper-based diagnostic format, neutralizes influ
    81 rochemical immunosensor capable of detecting HA with high sensitivity and selectivity was developed. 
  
    83  support for a model in which PEP87 disrupts HA function by displacing native interactions of the neu
  
  
  
    87 o increase bioaccessibility, we encapsulated HAs in lipid-core nanocapsules (NCs) based on a biodegra
  
    89 the elongated 260-loop increases the exposed HA surface and can contribute to antigenic variation in 
  
  
  
    93 clade classifications, an automated tool for HA subtype numbering conversion, linkouts to disease eve
  
  
  
    97 oblasts isolated from control mice generated HA-enriched cable structures in the ECM, providing a sub
  
  
  
  
  
  
   104 overlaps with the pocket occupied by some H3 HA-specific inhibitors, indicating the high relevance of
   105 nt formulations to broaden responses to H5N1 HA based antigens, and show that this broadening is func
   106 T-cell epitopes and low immunogenicity of H7 HA remains unknown due to the lack of animal models repr
  
   108 cantly improved the immunogenicity of the H7 HA in the humanized mouse model, leading to a greater th
  
  
   111 rystal structure of m826 complexed with H7N9 HA indicates that m826 binds an epitope that may be full
   112 higher toward H7N9 NP, as compared with H7N9 HA or NA proteins, and correlated strongly with ADCC-Abs
  
  
  
   116 onjunctival and subcutaneous injection of HC-HA/PTX3 preserved tear secretion and conjunctival goblet
  
  
   119 a mouse model of cGVHD to examine whether HC-HA/PTX3 could attenuate dry eye disease elicited by cGVH
  
   121 performed by high cumulative/high annual (HC/HA) surgeons increased from 38.3% to 58.4% (P < 0.01) wi
  
  
  
  
   126 predicted phenotypic effects, hemagglutinin (HA) clade classifications, an automated tool for HA subt
   127  of the surface glycoproteins hemagglutinin (HA) and neuraminidase (NA) with the cell surface recepto
  
   129 ntified T-cell epitopes in H7 hemagglutinin (HA) which potentially enhance regulatory T cell response
   130 uished, based on variation in hemagglutinin (HA): B/Victoria/2/87-like (B/Vic) and B/Yamagata/16/88-l
   131  tetanus toxoid and influenza hemagglutinin (HA) from H1N1 and newly emergent subtypes such as H5N1 a
  
  
   134 ely on the antigenic match of hemagglutinin (HA) for vaccine strain selection, and most vaccines rely
   135 he influenza envelope protein hemagglutinin (HA), the low pH in the endosome triggers a transition fr
   136 nfected cells and recombinant hemagglutinin (HA), neuraminidase (NA), and nucleoprotein (NP) proteins
   137 s with relatively acid-stable hemagglutinin (HA) proteins are rendered incapable of pH-induced trigge
  
   139 usly acquire mutations in the hemagglutinin (HA) glycoprotein that abrogate binding of human antibodi
   140 to influenza virus target the hemagglutinin (HA) glycoprotein, which is the major antigen on the surf
  
   142 o acid at position 158 of the hemagglutinin (HA) protein substantially affected the systemic replicat
   143 ntibody responses against the hemagglutinin (HA) surface glycoprotein; however, the diversity of HAs 
   144    Key mutations in the virus hemagglutinin (HA) protein or reassortment with other pandemic viruses 
   145 f RIV4 (45 mug of recombinant hemagglutinin [HA] per strain, 180 mug of protein per dose) versus stan
   146 pe and mutant MN/10 or BJ/92 hemagglutinins (HAs) were constructed and probed for reactivity with fer
  
   148 uit is the posterior hypothalamic histamine (HA) system, implicated in supporting wakefulness and hig
  
  
  
  
  
   154 ma is characterized by excessive hyaluronan (HA) accumulation in the tumor microenvironment, elevatin
   155 ceptor for the glycosaminoglycan hyaluronan (HA) demonstrate a number of neurological disturbances in
   156 llular matrix (ECM), enriched in hyaluronan (HA) and its binding partner versican, which promotes mon
  
   158 CE STATEMENT We demonstrate that hyaluronan (HA) with different molecular weights produces opposing n
  
  
  
  
  
  
   165 glycoproteins induce ER stress, resulting in HA degradation via ERAD and consequent inhibition of IAV
  
  
   168 and that primary tumors can further increase HA immaturity even before secondary tumor formation, mim
  
   170 tabolism in Hyal2(-/-) mice causes increased HA, which may promote endothelial-to-mesenchymal transit
   171 able HA content, we confirmed that increased HA leads to mechanically softer hydrogels, consistent wi
   172 abnormalities were associated with increased HA, vimentin-positive cells, and fibrosis in Hyal2(-/-) 
  
  
  
   176 f chimeric VLPs (cVLPs) containing influenza HA and GPI-anchored CCL28 as antigen and mucosal adjuvan
  
  
  
  
   181  levels or engagement of CD44 by its ligand (HA) or a CD44-specific Ab reduced NF-kappaB translocatio
  
  
   184 ers, comprising bundles of small needle-like HA crystals, formed on etched surfaces that were cut per
   185 on of large, randomly distributed plate-like HA crystals that were weakly attached, regardless of rod
  
  
   188 tumor cell dissemination contain less-mature HA (i.e., smaller, less-perfect, and less-oriented cryst
   189 odel of localized breast cancer, metaphyseal HA nanocrystals were also smaller and less perfect than 
   190 ion of 2 amino acid mutations and a modified HA tag at the C terminus of PB1, which is sufficient to 
   191  to control membrane curvature and to modify HA's interaction with M1 protein, while the stunting of 
   192 e data demonstrate that disruption of normal HA catabolism in Hyal2(-/-) mice causes increased HA, wh
  
  
  
  
   197 nes of evidence suggest that the activity of HA neurons is important in the regulation of vigilance d
   198 ed glycosylation site in antigenic site B of HA emerged, and these viruses remain prevalent today.   
   199 zymes that synthesize the building blocks of HA, UDP-Glucuronic acid and UDP-N-Acetyl-Glucosamine, as
  
   201 dol stabilizes the prefusion conformation of HA that inhibits the large conformational rearrangements
  
   203 d both the electrophysiological diversity of HA neurons in brain slices and the effect of their acute
  
  
  
  
   208 und healing is demonstrated by inhibition of HA synthesis in a murine wound model by administering 4-
   209 umbelliferone, a small-molecule inhibitor of HA synthesis, reduced HA accumulation, diminished swelli
   210 raditional vaccines induced robust levels of HA inhibition (HI) titers, but failed to protect against
   211 r dose) versus standard-dose IIV4 (15 mug of HA per strain, 60 mug of protein per dose) to compare th
   212  a fundamental stage in the precipitation of HA, with PHOSPHO1 being identified as the principal enzy
   213  to the fluorescence and color properties of HA and that hydrogen peroxide might whiten HA-AAAs by ox
  
  
   216 t the acute, cell type-specific silencing of HA neurons during wakefulness is sufficient to not only 
   217 H3 numbering) in the major antigenic site of HA was reported to be responsible for the antigenic drif
  
  
   220 little is known about the optimal spacing of HA ligands, which ought to bridge binding sites within o
  
  
   223 This occurs despite the observed tendency of HA to inhibit colonization on bare glass surfaces when s
  
   225 face glycoprotein; however, the diversity of HAs across species and antigenic drift of circulating st
   226 receptor-binding site and the stem region on HA is severely constrained by their functional roles in 
   227  strain selection, and most vaccines rely on HA inhibition titers to determine efficacy, despite the 
  
   229  specific to the HA head and stalk, but only HA stalk-specific antibodies mediated ADCC efficiently a
  
   231 t influence VLP shape, lipid composition, or HA lateral spacing, acylation significantly affected env
   232 ngs did not exhibit increases in versican or HA in these regions and had strikingly reduced numbers o
   233 l region contained smaller and less-oriented HA nanocrystals relative to ones that constitute the dia
   234 ion that occurred in epidemic strains, other HA mutations can confer resistance to antibodies that re
   235 solate with six gene segments (PB2, PB1, PA, HA, NA, and NS) sharing >99% sequence identity with thos
   236      Here, we obtained two anti-A(H1N1)pdm09 HA monoclonal antibodies that failed to neutralize virus
   237 s with bimodal listening experience (CI plus HA in contralateral ear) completed a questionnaire that 
   238  The majority of continuing bimodal (CI plus HA) participants reported adapting to using both devices
   239 ound in the PRF (56.46% +/- 9.26%) and PRF + HA (63.39% +/- 16.52%) groups compared to controls (15.9
   240 effectiveness of autologous PRF versus PRF + HA in treatment of IBDs in patients with chronic periodo
   241 ity magnetic immunocapture to rapidly purify HA-tagged mitochondria from homogenized mammalian cells 
  
  
  
  
   246 -molecule inhibitor of HA synthesis, reduced HA accumulation, diminished swelling, and restored basal
   247 Strikingly, eIF4E inhibition alone repressed HA levels as effectively as directly targeting HA with h
  
   249 s diseases associated with oxidative stress, HAs can be exploited for attractive nutraceutical applic
  
  
  
   253   This work was based on the hypothesis that HA treatment altered the bladder urothelial layer and th
  
  
  
   257 allenge, and antibodies directed against the HA head were the major contributor toward immune protect
   258  aimed at boosting Ab reactivity against the HA stem region, also elicited an Igkappa-biased response
   259   Using recombinant viruses, we identify the HA genomic segment as the mediator of cell death inhibit
  
   261 her, our results indicate that shifts in the HA receptor affinity are just an early adaptation step o
   262 t viruses encoding amino acid changes in the HA stalk domain replicated well in vitro, and viruses in
   263 Arbidol binds in a hydrophobic cavity in the HA trimer stem at the interface between two protomers.  
   264  position towards the N-terminus side of the HA PCS (P2 position) avoided hydrophobic residues, where
   265 glycosylation at positions 158 to 160 of the HA protein and that this N-linked glycosylation enhanced
   266  augment the persistence and function of the HA-1 TCR CD8(+) T cells and includes only memory T cells
   267 9 safety switch to enable elimination of the HA-1 TCR T cells in case of toxicity; and (4) a CD34-CD2
   268 an optokinetic zone spans a ZII+/- pair: the HA zones span the P5+/- and P7+/- ZII stripe pairs, wher
   269 Moreover, our observations indicate that the HA prefusion structure (and perhaps the metastable state
  
   271 infection induced antibodies specific to the HA head and stalk, but only HA stalk-specific antibodies
  
   273 safety and efficacy and supports use of this HA filler for treatment of HIV-associated FLA with durab
  
  
  
  
  
  
   280   Among the four mutations detected, the two HA mutations were analyzed by generating recombinant vir
   281 ating H3N2 strains compared to the wild-type HA antigens that were represented in commercial influenz
   282 cted by antibodies elicited by the wild-type HA from viruses selected as the vaccine candidates.     
  
  
  
  
   287  antibodies that recognize influenza A virus HA can be protective, but the mechanism is not completel
   288 s of Arbidol in complex with influenza virus HA from pandemic 1968 H3N2 and recent 2013 H7N9 viruses.
  
   290 echanical stimulation, high molecular weight HA reduces sensitization, attenuating inflammatory and n
  
  
  
   294 rrets for the elicitation of antibodies with HA inhibition (HAI) activity against human seasonal H3N2
   295 d acute lung injury and, in association with HA, generates an ECM that promotes leukocyte infiltratio
  
   297 ly cocluster, but the association of M1 with HA or NA is dependent upon the means of expression.     
   298 .53 to 1.00; P = .049) and for patients with HA-high tumors (HR, 0.51; 95% CI, 0.26 to 1.00; P = .048
  
   300 s much HONO was formed when NO2 reacted with HA that was photoreduced by irradiation with UV-visible 
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。