ライフサイエンスコーパス: HAT

1 onse factor (ARF)-histone acetyltransferase (HAT).

2 or subtraction, as well as H-atom transfer (HAT).

3 se-catalysed, complexation-induced HAT (LBCI-HAT).

4 brucei causes human African trypanosomiasis (HAT).

5 tic) stage of human African trypanosomiasis (HAT).

6 mplex (4) after the initial H atom transfer (HAT).

7 onse factor (ARF)-histone acetyltransferase (HAT).

8 ocess as well as via hydrogen atom transfer (HAT).

9 at underwent intramolecular H-atom transfer (HAT).

10 tive agent of human African trypanosomiasis (HAT).

11 ealization of holographic acoustic tweezers (HAT).

12 nd cardiac CT 6 (2.4%) cases with high-grade HAT.

13 , and the subsequent in vivo experiments for HAT.

14 th significantly increased administration of HAT.

15 2-yl)amino)benzamide] as potential drugs for HAT.

16 viding evidence for early CNS involvement in HAT.

17 n vivo curative activity in a mouse model of HAT.

18 the inflammatory pathogenesis of late-stage HAT.

19 the same electronic-structure changes during HAT.

20 f MQ and ADN, photo-generated through ET and HAT.

21 ission paradox is key to finally eliminating HAT.

22 of the conserved W residue in both MULEs and hATs.

23 T)](2+) (TAP = 1,4,5,8-tetraazaphenanthrene, HAT= 1,4,5,8,9,12-hexaazatriphenylene) by hydroquinone (

24 The excited-state quenching of [Ru(TAP)2(HAT)](2+) (TAP = 1,4,5,8-tetraazaphenanthrene, HAT= 1,4,

25 processes, including hydrogen atom transfer (HAT), a Povarov-type reaction, and atom-transfer radical

26 , MOF (hMOF), a member of the MYST family of HATs, acetylates histone H4 at lysine 16 (H4K16ac).

27 rinsic kinase and histone acetyltransferase (HAT) activities that activates transcription of key prot

28 ken together, our results establish that the HAT activity of MOF is required to sustain MLL-AF9 leuke

29 onal change and significantly increases p300 HAT activity on histone H3K18 residues, which, in turn,

30 Conversely, MYC inhibits BRD4's HAT activity, suggesting that MYC regulates its own tran

31 esponse to small-molecule inhibition of p300 HAT activity.

32 ote transcription through SAGA DUB and Tip60 HAT activity.

33 ue to CBP/p300-allows RNA to stimulate CBP's HAT activity.

34 Loss of the histone acetyltransferase (HAT) activity blocks oogenesis, while loss of the H2B de

35 HAT administration increased from 0.03% of patients (95%

36 ssion analyses to examine temporal trends in HAT administration.

37 electivity and reactivity in metal-catalyzed HAT alkene coupling, and create a firm basis for elucida

38 dation of mechanisms in the growing class of HAT alkene cross-coupling reactions.

39 coupling, an important representative of the HAT alkene reactions.

40 documentation of an unusual form of directed HAT and are of crucial importance for defining the neces

41 kynurenine pathway is activated in clinical HAT and associated with CNS inflammatory responses.

42 The HAT and AT strains of C. jejuni exhibited significantly

43 Consistently, the HAT and AT strains were highly tolerant to oxidants, suc

44 inding of a nucleosome to SAGA displaces the HAT and DUB modules from the core-module surface, allowi

45 We computed the gas-phase energies for HAT and electron affinity (EA) of NACs and established H

46 in organic solutions, can be either PCET or HAT and is governed by the thermodynamics of these inter

47 ht, can be either reduced or oxidized by the HAT and nickel catalysts, respectively, indicating that

48 The enhanced HAT and PET have been confirmed by the escape yields of

49 P and MQ molecules with FeNP, a preferential HAT and PET process is eased.

50 g agent, LiAlH(4), to completely reduce both HAT and PRA-derived products and the relative quantitati

51 gated reacted with hydroxyl radical via both HAT and SPLET in the solvents investigated.

52 nd shows the intersection of metal-catalyzed HAT and thiol radical trapping HAT catalytic cycles to b

53 tioxidant and it can be better understood by HAT and TMC mechanisms as it has low BDE, DeltaHacidity

54 recent advances, the mechanism by which the HAT and transcriptional coactivator p300 mediates tumori

55 the evolutionary relationships between MULE, hAT and Transib elements and the V(D)J recombinase.

56 recombination reaction and the mechanism of hAT and Transib transposases including the importance of

57 d aerotolerance, such as hyper-aerotolerant (HAT) and aerotolerant (AT) strains, were more tolerant t

58 ionalization via 1,5-hydrogen atom transfer (HAT) and enables net incorporation of ammonia at the bet

59 highly conserved histone acetyltransferase (HAT) and histone deacetylase (HDAC) enzymes that were fi

60 ely regulated by histone acetyltransferases (HAT) and histone deacetylases, have been recognized as m

61 mbination of thermal hydrogen-atom transfer (HAT) and proton-coupled electron transfer (PCET) process

62 We found that second hydrogen atom transfer (HAT) and second sequential proton loss electron transfer

63 on via its histone acetyltransferase domain (HAT) and, as a result, activates gene expression by alte

64 Histone acetyltransferases (HATs) and histone deacetylases (HDACs) compete to modula

65 ns, catalysed by histone acetyltransferases (HATs) and histone deacetylases (HDACs), is a major epige

66 stic activity of histone acetyltransferases (HATs) and histone deacetylases (HDACs), is necessary for

67 domain (BRD), CH2 (comprising PHD and RING), HAT, and ZZ domains at 2.4-A resolution.

68 ectron affinity (EA) of NACs and established HAT- and EA-based LFERs for six hydroquinone species.

69 d photocatalytic and hydrogen atom transfer (HAT) approach for the light-mediated epimerization of re

70 Mutation, malfunction, and dysregulation of HATs are associated with a wide range of pathologies or

71 In summary, we provide evidence that both HATs are bona fide tumor suppressors that control MHCII

72 These results point to HAT as implausible for the reaction with nitric oxide ra

73 sics of what makes a surface icephobic ("ice-hating") as well as the relationship between icephobicit

74 In vitro HAT assays suggest that the RING domain, the autoregulat

75 sing steady-state histone acetyltransferase (HAT) assays, we show that an RNA binding region in the H

76 The primary outcome was receipt of HAT at least once during hospitalization.

77 The HAT at unactivated C(sp(3))-H sites is enabled by the ea

78 irst independent, experimental validation of HAT-based LFER, a new approach that enables rate predict

79 ful probe for biological studies of p300/CBP HAT but also a pharmacological lead for further drug dev

80 e iron center modulates not only the rate of HAT but also the rate of ligand rebound.

81 tion step pertains to a diffusion-controlled HAT by (3)O(2) from the 10-OH-9-anthroxyl radical.

82 A kinetic analysis shows that the HAT by chain-carrying HO(2)(*) occurs with a high rate c

83 P on the MQ-ADN complex ((Au)MQ-ADN) assists HAT by limiting the ET channel, on the other hand, FeNP

84 entered radical that forms after the initial HAT by the high valent oxoiron complex depends on the ox

85 in the strength of the O-H bond formed after HAT by the oxoiron unit, the O-H bond derived from 3 bei

86 Hydrogen atom transfer (HAT) by (3)O(2) and HO(2)(*) from arenols (ArOH), arylox

87 tween intermolecular hydrogen-atom transfer (HAT) catalysis and intramolecular [1,5] HAT was observed

88 toredox, enamine and hydrogen-atom transfer (HAT) catalysis-enables an enantioselective alpha-aldehyd

89 with azide ion as a hydrogen atom transfer (HAT) catalyst, provides a direct synthesis of alpha-tert

90 n Y, which acts as a hydrogen atom transfer (HAT) catalyst.

91 tal-catalyzed HAT and thiol radical trapping HAT catalytic cycles to be essential for effective catal

92 ATs, also termed histone acetyltransferases, HATs) catalyze the acetylation of substrate lysine resid

93 , a proxy for the highest astronomical tide (HAT), changes over seasonal and interannual time scales.

94 tate density function theory revealed a high HAT character, yet multiconfigurational nature in the tr

95 gests intermolecular hydrogen atom transfer (HAT) chemistry is at play, rather than classical Norrish

96 base catalyst, and a hydrogen-atom transfer (HAT) co-catalyst.

97 enes by interfering with the function of the HAT complex during infection.

98 PsAvh23 binds to the ADA2 subunit of the HAT complex SAGA and disrupts its assembly by interferin

99 in is similar to that of acyl-CoA-bound p300 HAT complexes and shows that the acetyl-CoA binding site

100 F6L, components or co-activators of the GNAT-HAT complexes for the mouse ESC (mESC) state.

101 etylation, a small-molecule inhibitor of the HAT component MYST blocked the growth of both murine and

102 Heteromeric amino acid transporters (HATs) comprise a group of membrane proteins that belong

103 nolinium salts under hydrogen atom transfer (HAT) conditions, and an expanded scope for the coupling

104 ing sickness (Human African Trypanosomiasis, HAT), contains a kinetoplast with the mitochondrial DNA

105 es encoding the histone acetyl-transferases (HATs) CREB binding protein (CREBBP) and EP300 are recurr

106 nes encoding the histone acetyltransferases (HATs) CREBB-binding protein (CREBBP) and EP300 are commo

107 Our analysis of the HAT cycle indicated that activation of a alpha-amino C(s

108 n-coupled electron transfer-mediated reverse HAT cycle of eosin Y.

109 es that cause human African trypanosomiasis (HAT), depend on ornithine uptake and metabolism by ornit

110 Using this library, we demonstrate that HAT/DESC proteases are dispensable for term development,

111 new congenic mouse strains for the study of HAT/DESC proteases in physiological and in pathophysiolo

112 ngenic mouse strains lacking combinations of HAT/DESC proteases, including a mouse strain deficient i

113 dermal barrier formation is unique among all HAT/DESC proteases.

114 ally expressed in a squamous cell carcinoma (HAT/DESC) cluster of membrane-anchored serine proteases.

115 lpha gene, and inactivating mutations in its HAT domain abolished its ability to regulate ERalpha, su

116 In summary, we identified the p300/CBP HAT domain as a putative therapeutic target in highly th

117 Partial deletion of the HAT domain in the CBP gene, blocked these effects.

118 The structure of the apo-CBP HAT domain is similar to that of acyl-CoA-bound p300 HAT

119 s, we show that an RNA binding region in the HAT domain of CBP-a regulatory motif unique to CBP/p300-

120 The HAT domain of p300/CBP is a potential drug target for ca

121 ain, the autoregulatory loop (AL) within the HAT domain, and the ZZ domain do not directly influence

122 ally disordered AL are autoacetylated by the HAT domain.

123 n of MAML1 to the histone acetyltransferase (HAT) domain of p300 rescues expression of HES4 but not D

124 The BRD, PHD, and HAT domains form an integral structural unit to which th

125 nd that the thermal isomerization rate of C6 HAT drastically increases on metal surfaces, the thermal

126 High-grade HAT/DRT was associated with thromboembolism in 2 cases,

127 me-infected mice; it is an advanced lead for HAT drug development.

128 The pyrrolopyrimidine AEE788 (a hit for anti-HAT drug discovery) associates with three trypanosome pr

129 thine, which is antagonistic to another anti-HAT drug, suramin.

130 f which affect sensitivity to important anti-HAT drugs.

131 o enantiodetermining hydrogen-atom transfer (HAT) during the C-H amination event.

132 this study, we evaluated the feasibility of HAT energy for predicting NAC reduction rate constants.

133 The results suggest that HAT energy is a reliable predictor of NAC reduction rate

134 indicate that leptin, acting via an AKT-p300 HAT epigenetic cascade, induces exon-specific Bdnf expre

135 C6 HAT exhibits a half-life of 789 years in solution.

136 weakened rhythmicity, whereas reducing Tip60 HAT expression drastically weakened rhythmicity.

137 identification of large numbers of new DTA (hAT) family elements, which have all the hallmarks of bo

138 The histone acetyltransferase (HAT) family of proteins performs histone acetylation.

139 The hopper hAT-family transposable element isolated from the Orient

140 pronged methodology, involved performing top-hat filtering, second order statistical filtering, and t

141 xamples shown here suggest the future use of HAT for novel forms of displays in which the objects are

142 e FtmOx1 mechanism revealed, instead, direct HAT from C21 to the ferryl complex and surprisingly comp

143 reactions occur: (a) hydrogen-atom transfer (HAT) from a donor to the peroxyl radical; (b) peroxyl ra

144 ng reactions involve hydrogen atom transfer (HAT) from a metal-hydride species to an alkene to form a

145 Hydrogen-atom transfer (HAT) from a substrate carbon to an iron(IV)-oxo (ferryl)

146 ude slower than 3 in hydrogen atom transfer (HAT) from C-H bonds.

147 ing ability of S via hydrogen atom transfer (HAT) from TEMPO-H (2,2,6,6-tetramethylpiperdine-N-hydrox

148 posed to operate via hydrogen atom transfer (HAT) from the substrate to the photoexcited TAC radical

149 at utilizes computed hydrogen atom transfer (HAT) Gibbs free energy instead of E(H)(1) as a predictor

150 s of the mechanisms of the photoredox-nickel-HAT (HAT: hydrogen atom transfer) catalyzed arylation an

151 N5 inhibitor and forebrain tissue from (Gcn5(hat/hat) ) embryos, we demonstrate that GCN5, RARalpha/g

152 on and transcriptional defects seen in (Gcn5(hat/hat) ) mutants can be rescued with gestational RA su

153 ctivity of the acetyltransferase GCN5 ((Gcn5(hat/hat) )), which were previously characterized with re

154 We show that like AD, disruption of Tip60 HAT/HDAC2 balance with concomitant epigenetic repression

155 ibitory scaffolds within the GlaxoSmithKline HAT (Human African Trypanosomiasis) and Chagas chemical

156 the mechanisms of the photoredox-nickel-HAT (HAT: hydrogen atom transfer) catalyzed arylation and alk

157 ect and atom-economical, enabled by a Shenvi-HAT hydrogenation.

158 H iodination via 1,5-hydrogen atom transfer (HAT), (ii) desaturation via I(2) complexation, and (iii)

159 Cardiac CT demonstrated low-grade HAT in 9 (3.6%) cases at 8 weeks; and 13 cases (9.4%) at

160 reased interest in new strategies to perform HAT in a sustainable manner.

161 mising druggable target for the treatment of HAT in both stages 1 and 2 of the disease.

162 of the importance of hydrogen atom transfer (HAT) in biology and chemistry, there is increased intere

163 suppresses autoxidation by H-atom transfer (HAT) in favor of addition, such that the epoxides are th

164 as a modulator of histone acetyltransferase (HAT) in plants.

165 tramolecular 1,5-hydrogen atom transfer (1,5-HAT) in the decay of a PEGylated carbazyl (aminyl) radic

166 kynurenine pathway activation occurs during HAT, including cases prior to the current diagnostic cut

167 Consortium (SGC) and identified the p300/CBP HAT inhibitor A-485, in addition to the well-known BET i

168 Moreover, the Tip60/HAT inhibitor, NU9056, was able to block EtOH-induced H4

169 The histone acetyltransferase (HAT) inhibitor garcinol or vehicle was injected followin

170 We profile the most commonly used HAT inhibitors and confirm that the majority of them are

171 Several histone acetyltransferase (HAT) inhibitors with these liabilities are now routinely

172 It first serves as a HAT initiator and subsequently functions as a silyl radi

173 sited that tyrosine (Tyr or Y) 224 serves as HAT intermediary to separate the C21 radical (C21*) and

174 Different pathways have been discerned for HATs involving OH or CH moieties.

175 The catalytic LBCI-HAT is capable of accessing both branch-specific hydrosi

176 Mechanistic experiments indicate HAT is rate-limiting, whereas intramolecular amination i

177 We find that the variability in HAT is significantly correlated with sea-level variabili

178 Human African trypanosomiasis (HAT) is a neglected tropical disease caused by infection

179 is controlled by histone acetyltransferases (HATs/KATs) found in multiprotein complexes that are recr

180 In Western analysis, HAT-L4 expressed in transfected CHO cells appeared as a

181 Here we examined HAT-L4 expression and function in vitro and in vivo.

182 Flow cytometry confirmed HAT-L4 expression on the cell surface with the expected

183 In the skin, HAT-L4 expression was abundant in keratinocytes and seba

184 These results indicate that HAT-L4 is important in epidermal barrier function to pre

185 We generated HAT-L4 knockout mice by disrupting the Tmprss11f gene en

186 HAT-L4 knockout mice were viable and fertile.

187 nd immunostaining experiments indicated that HAT-L4 was expressed in epithelial cells and exocrine gl

188 Human airway trypsin-like protease 4 (HAT-L4) is a type II transmembrane serine protease.

189 In metabolic studies, HAT-L4-deficient adult mice drank water more frequently

190 Compared with wild-type controls, HAT-L4-deficient newborn mice had greater body fluid los

191 ce by disrupting the Tmprss11f gene encoding HAT-L4.

192 g Lewis base-catalysed, complexation-induced HAT (LBCI-HAT).

193 tivates histone acetyltransferase p300 (p300 HAT), leading to changes in histone H3 acetylation and m

194 Increasing Tip60 HAT levels specifically in the mushroom body learning an

195 that the recently described function of the HAT-like 4 protease in epidermal barrier formation is un

196 elieve that this reaction undergoes a direct HAT mechanism catalyzed by eosin Y.

197 that both reactions proceed through a common HAT mechanism.

198 c forms undergo only hydrogen atom transfer (HAT) mechanism with CH(3)OO.

199 3.5), implicating a hydrogen atom transfer (HAT) mechanism.

200 nlisting late-stage, hydrogen atom transfer (HAT)-mediated free radical bond formations (C20-C2 and C

201 regulate transcription independently of the HAT module.

202 core module, the histone acetyltransferase (HAT) module and the histone deubiquitination (DUB) modul

203 covered the H4K16 histone acetyltransferase (HAT) MOF to be important for leukemia cell growth.

204 cardiac CT demonstrates cases with low-grade HAT, not visualized by TEE.

205 tion mechanism to explain the behavior of C6 HAT on these different metal surfaces.

206 d for presence of hypoattenuated thickening (HAT) on the device, which was subclassified as low grade

207 cidic and neutral media 5CQA can take either HAT or RAF pathways.

208 cterized as either a hydrogen-atom transfer (HAT) or a concerted proton-coupled electron transfer (cP

209 ive agent for human African trypanosomiasis (HAT) or sleeping sickness.

210 Human African trypanosomiasis (HAT), or African sleeping sickness, is a fatal disease f

211 Human African trypanosomiasis (HAT), or sleeping sickness, is caused by the protozoan p

212 (H(+)) travel "together" as a true H atom, (HAT), or whether the H(+) and e(-) are transferred in co

213 The MS-CPET and HAT oxidations of TEMPOH at the same driving force occur

214 This likely indicates that HAT-P-26b's atmosphere is primordial and obtained its ga

215 ance as a proxy for metallicity, we measured HAT-P-26b's atmospheric heavy element content ([Formula:

216 udy of the transiting Neptune-mass exoplanet HAT-P-26b.

217 Histone acetyltransferase (HAT) p300 and its paralog CBP acetylate histone lysine s

218 en a pendant phenol is present, it follows a HAT pathway with a pendant quinol.

219 t tunneling underlies the preference for the HAT pathway.

220 on transfer (ET) and hydrogen atom transfer (HAT) pathways between an anti-tumor drug vitamin-K3 (MQ)

221 we describe a sustainable, net redox-neutral HAT process involving hydrosilanes and alkali metal Lewi

222 dicals with toluene, which indicate that the HAT process is characterized by a significant degree of

223 Consequently, the HAT process performed by 1 occurs on the triplet surface

224 of polar effects in hydrogen atom transfer (HAT) processes is made difficult by the fact that in mos

225 radicals mediate 1,6-hydrogen-atom transfer (HAT) processes to guide gamma-C(sp(3) )-H chlorination.

226 parate the C21 radical (C21*) and Fe(III)-OH HAT products and prevent rebound.

227 shifted from a "Mexican hat" to a "stovepipe hat" profile, with stronger excitation in the core and w

228 with that of 2,6-dimethyl-3-methoxyphenol in HAT promoted by a series of radicals (cumyloxyl, galvino

229 polar effects in the HAT reaction, i.e., in HAT promoted by N-oxyl radicals containing electron-with

230 hen considered on the scale of a wavelength, HAT provides similar manipulation capabilities as HOT wh

231 nvestigations of the hydrogen atom transfer (HAT), radical adduct formation (RAF), sequential proton

232 ith HO, anionic forms of 5CQA conform to the HAT, radical adduct formation, sequential proton loss el

233 In line with our predictions, the ratio of HAT rate constants ( k(H) (mOMe)/ k(H)(H)) is larger in

234 The HAT rate constants are significantly higher than those o

235 nced by the 10(4)-10(7)-fold decrease in the HAT rate constants in acetonitrile following addition of

236 ponent reactions are compared with a related HAT reaction of TEMPOH, with the 2,4,6-tri-tert-butylphe

237 The approach to 1 features an Fe-mediated HAT reaction of the intermediate olefin 2, effecting a t

238 greater contribution of polar effects in the HAT reaction, i.e., in HAT promoted by N-oxyl radicals c

239 is dictated by a 1,5-hydrogen atom transfer (HAT) reaction by a pendent amide.

240 been used to determine the rate constants of HAT reactions (k(H)), but no radical clock is available

241 kinetic study of the hydrogen atom transfer (HAT) reactions from a series of organic compounds to the

242 kinetic study on the hydrogen atom transfer (HAT) reactions from the aliphatic C-H bonds of a series

243 n transfer (SET) and hydrogen atom transfer (HAT) reactions, thus covering all the physiologically re

244 An increase in the HAT reactivity of QINO was observed in the presence of 0

245 n, that Fe(III)-OOH species being formed via HAT reactivity of the partner ferric heme superoxide com

246 Relying on 1,5-HAT reactivity, these methods are limited to beta - or d

247 f substrates via C-H hydrogen atom transfer (HAT), reducing 1 to [(PyPz)Fe(II)(OH2)2](4+) (2).

248 Low-grade HAT resolved spontaneously over time.

249 tected 2 (1.4%) cases with DRT or high-grade HAT, respectively.

250 After the HAT-selection and cloning, we established nine hybridoma

251 ed to study the photoisomerization of the C6 HAT self-assembled monolayers (SAMs) on Au, Ag, and Cu s

252 of free radical scavenging activity, namely HAT, SET-PT and SPLET.

253 alization was studied by dynamically-loading hat-shaped specimens to induce forced shear localization

254 Compound 1 features a hat-shaped structure with the parent wheel-shaped {Mo150

255 the current policy not to treat asymptomatic HAT should be reconsidered.

256 ical approaches, such as a facile remote C-H HAT step, with that of transition-metal-catalyzed chemis

257 into the origin of enantioselectivity in the HAT step.

258 ical precursor facilitates catalyst-mediated HAT stereoselectivity, enabling the synthesis of several

259 f aerotolerance in C. jejuni and that AT and HAT strains of C. jejuni are more tolerant to oxidants a

260 The AT and HAT strains that were tolerant to stresses, particularly

261 ndant cut-and-paste transposons are from the hAT superfamily.

262 are organized into a hydrophobic, or "water-hating," surface that is considered to form a major site

263 It was found that C6 HAT switches on Au and Cu surfaces when irradiated with

264 experimentally demonstrate a 40-kHz airborne HAT system implemented using two 256-emitter phased arra

265 nger than that for 1-H, which decays via 1,5-HAT (tau1/2 = 48 s, DeltaH(double dagger) = 10.0 +/- 0.3

266 N, indicative of alpha-CH2 deactivation with HAT that predominantly occurs from the most remote methy

267 a fork-associated histone acetyltransferase (HAT) that regulates the stability of stalled forks and t

268 tramolecular 1,5-hydrogen atom transfer (1,5-HAT) that was observed in its constitutional isomer 1-H

269 18 cured 60% of mice in a systemic model of HAT, the compound was unable to clear parasitemia in a C

270 In an effort to develop new HAT therapeutics, we report the structure-activity relat

271 shock, we compared the association of early HAT therapy (within 2 d of hospitalization) with hospita

272 study aims to describe the administration of HAT therapy among U.S. adults with septic shock before a

273 sone, high-dose ascorbic acid, and thiamine (HAT therapy) was published online.Objectives: This study

274 mong 338,597 patients, 3,574 (1.1%) received HAT therapy, 98.7% in the postpublication period.

275 en patients who received and did not receive HAT therapy.Methods: We performed a retrospective cohort

276 /mol) Fe-H bond, which performs irreversible HAT to alkenes in contrast to previous studies on isolab

277 n of the metal catalyst by O(2) and a second HAT to form the unprotected saturated N-heterocycle appe

278 on of the C-H bonds alpha to nitrogen toward HAT to PINO as evidenced by the 10(4)-10(7)-fold decreas

279 * peroxyl adduct to olefinic C27 followed by HAT to the C26* from a Tyr.

280 nses to mossy fibers shifted from a "Mexican hat" to a "stovepipe hat" profile, with stronger excitat

281 ough two successive hydrogen atom transfers (HAT) to 2 equiv of phenoxyl that are generated transient

282 ctivity of TEMPOH by hydrogen atom transfer (HAT) to a single e(-)/H(+) acceptor.

283 al hydrogenation via hydrogen atom transfer (HAT) to alkenes is an increasingly important transformat

284 t a metal hydride hydrogen atom transfer (MH-HAT) to generate a C-centered radical that undergoes add

285 irecting its regioselective H atom transfer (HAT) to the beta carbon of an alcohol.

286 ability of seven histone acetyltransferases (HATs) to catalyze acylations on histones in vitro using

287 nd order (NEVPT2), provided insight into the HAT trajectories of 1 and A.

288 employed an innovative progressive black top hat transformation method to estimate them on a global s

289 We found that the hAT transposase TcBuster from Tribolium castaneum formed

290 sformations, notably hydrogen atom transfer (HAT) triggered processes, which can be promoted through

291 usly uncharacterized interaction between two HAT units is mediated via dimerization of the heavy chai

292 This regioselective HAT was also rendered enantioselective by harnessing ene

293 Receipt of early HAT was associated with higher hospital mortality (28.2%

294 High-grade HAT was considered as definite DRT.

295 patients with early septic shock, receipt of HAT was not associated with mortality benefit.

296 hromboembolism in 2 cases, whereas low-grade HAT was not related to embolic events.

297 fer (HAT) catalysis and intramolecular [1,5] HAT was observed through precise manipulation of the pro

298 onalized with a C6 alkyl thiolate spacer (C6 HAT) was characterized on a number of metal surfaces.

299 inal chemistry, novel inhibitors of p300/CBP HAT with their IC(50) values as low as 620 nM were disco

300 RAF pathways are faster, but HAT yields thermodynamically more stable radical product