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1 HFOV animals had significantly better lung inflation pat
2 HFOV increased barotrauma risk compared with conventiona
3 HFOV increases mortality for most patients with ARDS but
4 ho were treated with HFOV plus iNO (n = 14), HFOV alone (n = 12), CMV plus iNO (n = 35), and CMV alon
13 24 hrs of treatment, both HFOV plus iNO and HFOV alone resulted in greater improvement in Pao2/Fio2
15 , MPO activity from lung extracts of PLV and HFOV animals was significantly lower than that of CMV an
17 ng samples of animals supported with PLV and HFOV had significantly lower neutrophil counts when comp
18 index was affected by rotating position and HFOV mode of ventilation after 10 mL/kg of perflubron, a
19 uld compare different algorithms of applying HFOV to determine the optimal techniques for achieving o
23 culate that the enhanced lung recruitment by HFOV enhances the effects of low dose iNO on gas exchang
26 tal of 1764 patients were matched to compare HFOV and CMV, whereas 942 patients were matched to compa
27 multicenter, randomized trial that compared HFOV with conventional ventilation immediately after bir
28 stress syndrome patients (n = 148) comparing HFOV with a pressure-control ventilation strategy (Pao(2
29 ently identified randomized trials comparing HFOV with conventional ventilation for adults with ARDS.
32 bjective method (1) to optimize P(aw) during HFOV and (2) to assess the efficacy of treatments and pr
33 directly monitor lung volume changes during HFOV and use the lowest possible airway pressures after
34 pressure-volume curve was constructed during HFOV as mean airway pressure was increased from 10 to 40
37 c effects of varying perflubron doses during HFOV in a long-term study of the lung-protective effects
38 Although heliox improved gas exchange during HFOV in our model, increased tidal volume delivery may l
42 arly HFOV included 1,064 patients (181 early HFOV vs. 883 CMV/late HFOV) with significant hypoxia (ox
45 After adjusting for risk category, early HFOV use was associated with a longer duration of mechan
48 redicting the probability of receiving early HFOV included 1,064 patients (181 early HFOV vs. 883 CMV
50 uding important oxygenation variables, early HFOV was associated with a longer duration of mechanical
51 V: 14.6 vs 20.3 days, P < .001; CMV vs early HFOV: 14.6 vs 15.9 days, P < .001), ICU length of stay (
54 nical ventilation for ARDS to undergo either HFOV with a Novalung R100 ventilator (Metran) or usual v
55 tality at 30 days was 321 of 785 (40.9%) for HFOV patients versus 288 of 767 (37.6%) for control subj
58 ustained improvements in oxygenation at 4 h (HFOV a/AO2 = 0.27 +/- 0.06, CV + PLV a/AO2 = 0.25 +/- 0.
61 ed with CMV (PLV, 4 +/- 0.3 neutrophils/hpf; HFOV, 4 +/- 0.5 neutrophils/hpf; CMV, 10 +/- 0.9 neutrop
63 8.1%, P < .001) were significantly higher in HFOV and early HFOV patients compared with CMV patients.
64 ary mechanics were significantly improved in HFOV animals at nearly every time point analyzed from 12
65 It is currently unknown whether initiating HFOV at a lower severity threshold would result in reduc
67 the individual and combined effects of iNO, HFOV, and PLV (perflubron) in 31 extremely premature lam
68 , 61 +/- 13.3 units of MPO activity/lung/kg; HFOV, 43.3 +/- 6.8 units of MPO activity/lung/kg; CMV, 1
70 64 patients (181 early HFOV vs. 883 CMV/late HFOV) with significant hypoxia (oxygenation index >/= 8)
73 ugh enhanced alveolization was not observed, HFOV for 1 to 2 mo resulted in consistently more uniform
75 oderate-to-severe ARDS, early application of HFOV, as compared with a ventilation strategy of low tid
79 ere were significant differences in favor of HFOV in several other measures of respiratory function,
81 suggested that early (2 days) initiation of HFOV is more likely to result in survival than delayed i
82 nventional ventilation before institution of HFOV compared with patients without preexisting lung dis
83 ide useful information on the interaction of HFOV with altered lung mechanics and may contribute to t
85 erol delivery by MDI in a pediatric model of HFOV is negligible, regardless of the operating frequenc
87 e, case reports and observational studies of HFOV in patients failing conventional ventilation strate
88 hypothesized that the combined treatment of HFOV and inhalation of low-dose NO would improve oxygena
97 E, 353 patients (14%) were ever supported on HFOV, of which 210 (59%) had HFOV initiated within 24-48
99 antly lower than that of animals in the PLV, HFOV, and CMV groups (control, 2.2 +/- 2 units of MPO ac
103 study was to compare the effect of prolonged HFOV with low tidal volume (VT) positive pressure ventil
106 esized that two lung recruitment strategies (HFOV and PLV) would have similar effects on gas exchange
113 (SatPC) in alveolar lavage was lower for the HFOV group than for the other ventilation groups at 10 h
114 red with the conventional-therapy group, the HFOV group had significantly higher ratings from teacher
115 curred in 166 of 398 patients (41.7%) in the HFOV group and 163 of 397 patients (41.1%) in the conven
117 mprovement in Pao(2)/Fio(2) (p =.008) in the HFOV group but no significant difference in oxygenation
120 to 240], P<0.001), and more patients in the HFOV group than in the control group received neuromuscu
123 change in Pao /Fio ratio was greatest in the HFOV plus iNO group compared with the other treatment gr
126 s with new-onset, moderate-to-severe ARDS to HFOV targeting lung recruitment or to a control ventilat
127 dolescents who had been randomly assigned to HFOV with follow-up data from those who had been randoml
130 Respiratory therapy procedures relevant to HFOV include setting endotracheal tube cuff leaks, perfo
132 tremely prematurely, those who had undergone HFOV, as compared with those who had received convention
134 a(CO(2)) 55-80 mm Hg), each piglet underwent HFOV with a fixed mean airway pressure, pressure oscilla
136 this Opinion, the clinical experience using HFOV in adults in acute respiratory distress syndrome an
139 from high-frequency oscillatory ventilation (HFOV) and mechanical test lung models with respect to de
140 h as high-frequency oscillatory ventilation (HFOV) and partial liquid ventilation (PLV) also decrease
141 e of high-frequency oscillatory ventilation (HFOV) for acute respiratory failure in children is preva
142 e of high-frequency oscillatory ventilation (HFOV) has increased dramatically in the management of re
143 that high-frequency oscillatory ventilation (HFOV) improves lung function, mechanics, and histopathol
145 e of high-frequency oscillatory ventilation (HFOV) in children with acute respiratory failure have no
147 ALE: High-frequency oscillatory ventilation (HFOV) is theoretically beneficial for lung protection, b
149 that high-frequency oscillatory ventilation (HFOV) reduced mortality among adults with the acute resp
151 idal high-frequency oscillatory ventilation (HFOV) while the lungs are expanded by an imposed airway
152 that high-frequency oscillatory ventilation (HFOV), as compared with conventional ventilation, was as
153 with high-frequency oscillatory ventilation (HFOV), we developed and bench tested a system that permi
158 vs. high-frequency oscillatory ventilation [HFOV]) on perflubron distribution and oxygenation improv
159 Length of mechanical ventilation (CMV vs HFOV: 14.6 vs 20.3 days, P < .001; CMV vs early HFOV: 14
161 rway function (z score for FEF75, -0.97 with HFOV vs. -1.19 with conventional therapy; adjusted diffe
162 e control group (relative risk of death with HFOV, 1.33; 95% confidence interval, 1.09 to 1.64; P=0.0
168 made between patients who were treated with HFOV plus iNO (n = 14), HFOV alone (n = 12), CMV plus iN
169 al piglet model of pneumothorax treated with HFOV, with amplitude adjusted to maintain constant alveo
171 ntial role of adjunctive therapies used with HFOV (e.g., prone ventilation, inhaled nitric oxide, aer
172 n the creation and implementation of written HFOV guidelines (e.g., algorithms) to optimize patient c
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