ライフサイエンスコーパス: HGF receptor

1 d competed with HGF for binding to the c-Met HGF receptor.

2 containing the entire coding sequence of the HGF receptor.

3 32D cells transfected with c-Met, the human HGF receptor (32D/c-Met).

4 elial cells through phosphorylation of c-Met/HGF receptor and activation of the ERK2 signaling pathwa

5 HGF receptor and transforming growth factor alpha (TGF-a

6 receptors for fibroblast growth factors, the HGF receptor c-Met binds tightly to HS.

7 ts showing that a selective inhibitor of the HGF receptor c-Met increased lung collagen to WT levels

8 tein because it interacts with both EGFR and HGF receptor c-Met pathways.

9 Pkd1-null mouse cells due to failure of the HGF receptor c-Met to be properly ubiquitinated and subs

10 is of downstream signaling revealed that the HGF receptor c-Met was equally activated in confluent an

11 els of active HGF and phosphorylation of the HGF receptor c-met were increased after muscle injury in

12 All melanocytic cells expressed the HGF receptor c-Met, and autocrine HGF caused constitutiv

13 HGF receptor c-met, fibroblast growth factor (FGF)-3, it

14 PHTx also increased activation of the HGF receptor c-Met, which was detected more then 9 hours

15 ion of HGF and endothelial activation of the HGF receptor c-Met.

16 t to determine how hepatocyte growth factor (HGF) receptor c-Met and epidermal growth factor receptor

17 Bcl-xl and the hepatocyte growth factor (HGF) receptor c-Met are both highly expressed in mesothe

18 engagement of the hepatocyte growth factor (HGF) receptor c-Met by heart-produced HGF during priming

19 n of the oncogenic hepatocyte growth factor (HGF) receptor c-MET in PNETs.

20 Activation of the hepatocyte growth factor (HGF) receptor c-met results in the regulation of cell-ma

21 kidney; (2) similar PTH type I receptor and HGF receptor (c-met) expression levels in the proximal t

22 atocyte growth factor (HGF) levels and renal HGF receptor (c-MET) gene expression.

23 tion of PGE2 as well as expression of Cox-2, HGF receptor (c-Met-R), epidermal growth factor receptor

24 terized mice with pancreatic deletion of the HGF receptor, c-Met (PancMet KO mice), in two models of

25 The HGF receptor, c-Met, was minimally phosphorylated in con

26 with this downregulation, phosphorylation of HGF receptor, c-Met, which is frequently overexpressed i

27 oid cell line 32D transfected with the human HGF receptor, c-Met.

28 einases, decreased hepatocyte growth factor (HGF) receptor, c-met proto-oncogene, and impaired wound

29 The hepatocyte growth factor (HGF) receptor, c-met, transduces the HGF multiple biolog

30 cells express the hepatocyte growth factor (HGF) receptor, c-Met.

31 except in the headfold state (when only the HGF receptor can be detected) and in the heart at the 14

32 ing mutations in the MET proto-oncogene (the HGF receptor) cause familial RCC, we investigated whethe

33 nto G(Alert) and that signalling through the HGF receptor cMet is also necessary.

34 prostate cancer cells induces activation of HGF-receptor/cMet and stimulates hyaluronan/CD44v9 signa

35 Phosphorylated HGF receptor coimmunoprecipitated with Shc, Grb2, and So

36 orting of cells engineered to express HGF or HGF receptor compared with control cell lines, enzyme-li

37 Hepatocyte Growth Factor (HGF) receptor, encoded by the protooncogene c-met, is ov

38 applied to study the distribution of HGF and HGF receptor expression in rabbit lacrimal gland tissue

39 s express Hgf, and selective deletion of the Hgf receptor gene in respiratory epithelium phenocopies

40 hese data provide fundamental information on HGF receptor gene organization, as well as on the genomi

41 ed in vivo expression of VEGF receptor-2 and HGF receptor in retrolental membranes from 16 patients w

42 Activation of the hepatocyte growth factor (HGF) receptor in epithelial cells results in lamellipodi

43 inked to cMet, the hepatocyte growth factor (HGF) receptor, in tumor cells, and this interaction decr

44 The hepatocyte growth factor (HGF) receptor is a tyrosine kinase transmembrane protein

45 sufficient for binding and activation of the HGF receptor, lacks the ability to super-activate the Ra

46 n reaction method was used to detect HGF and HGF receptor messenger RNA in human lacrimal gland tissu

47 ussman and colleagues show that blocking the HGF receptor MET abrogates HGF's rescue of drug sensitiv

48 that hepatocyte growth factor (HGF) and the HGF receptor MET might support some types of enteric neu

49 by HMGB1/TLR-4-dependent down-regulation of HGF receptor MET on MSC, thereby impairing HGF-driven MS

50 The hepatocyte growth factor (HGF) and the HGF receptor Met pathway are important in the pathogenes

51 h factor (HGF) resulted in activation of the HGF receptor MET, reactivation of the mitogen-activated

52 nase domain of the hepatocyte growth factor (HGF) receptor Met, enhance Met downstream signaling, and

53 Janus kinase 1 (Jak1), Shc, Grb2, Sos1, and HGF receptor (met).

54 asis, and dysregulated signaling through the HGF receptor, Met, contributes to tumorigenesis, tumor p

55 resistance mediated by up-regulation of the HGF receptor, MET.

56 The hepatocyte growth factor (HGF) receptor, Met, is a strong prognostic indicator of

57 HGF receptor mRNA is detected in the mesoderm of the hea

58 t the headfold stage, between E7.5 and E8.0, HGF receptor mRNA was detected in myocardial cells befor

59 on products of the expected size for HGF and HGF receptor mRNAs were detected in lacrimal tissue and

60 hrIL-7/HGFalpha cross-linked the IL-7 and HGF receptors on thymocytes, and the in vivo thymocyte-s

61 st that PIPKIgamma, downstream of EGF and/or HGF receptor, participates in breast cancer progression

62 F also triggered a 13-fold increase in c-Met/HGF receptor phosphorylation (P<0.005) and increased ERK

63 ced increase in ERK2 activity, but not c-Met/HGF receptor phosphorylation.

64 ression of Met, the hepatocyte growth factor(HGF) receptor, plays an important role in tumorigenesis.

65 ng directly to the hepatocyte growth factor (HGF) receptor, present on the surface of host cells.

66 The distribution of HGF receptor protein expression in the lacrimal gland su

67 ession of hepatocyte growth factor (HGF) and HGF receptor proteins in lacrimal gland, tears, and corn

68 Both VEGF receptor-2 and HGF receptor proteins were detected mainly in posterior

69 Binding of InlB to the HGF receptor results in mitogen-activated protein (MAP)

70 ice with inducible deletion of MET, we found HGF receptor signaling to regulate intestinal homeostasi

71 hat beta-catenin forms a complex with c-Met (HGF receptor) that undergoes dissociation because of bet

72 Immunohistochemically, HGF, as well as the HGF receptor (the met gene product), localized to signif

73 chial epithelium, and that expression of the HGF receptor, the c-met proto-oncogene protein, is unifo

74 interaction between the signals activated by HGF receptor tyrosine kinase and TGF-beta receptor serin

75 The Met/Hepatocyte Growth Factor (HGF) receptor tyrosine kinase is oncogenically activated

76 The HGF receptor was not different between control and IUGR

77 anchial arches, whilst Met, which encodes an HGF receptor, was expressed by subpopulations of cranial

78 F and InlB elicits similar activation of the HGF receptor, we observed striking differences in downst