ライフサイエンスコーパス: HIV Tat protein

1 iously cloned and shown to interact with the HIV Tat protein.

2 creased by treatment of cells with exogenous HIV-tat protein.

3 rming the chemotactic characteristics of the HIV-Tat protein.

4 The human immunodeficiency virus type 1 (HIV) Tat protein, a potent activator of HIV gene express

5 Treatment with HIV-tat protein activated NF-kappa B, degraded I kappa B

6 ences basal HIV gene expression and that the HIV Tat protein activates transcription independently of

7 ndothelium can be mimicked by treatment with HIV-Tat protein alone.

8 in transduction domain (PTD) embedded in the HIV TAT protein (amino acids 47-57) has been shown to su

9 Formation of a specific complex between the HIV Tat protein and the small RNA element TAR is critica

10 f (ARM) of the human immunodeficiency virus (HIV) Tat protein and TAR RNA is essential for Tat activa

11 We found HIV-Tat protein and IL-17-expressing mononuclear cells i

12 the protein transduction domain (PTD) of the HIV/TAT protein and transduced pancreatic islets ex vivo

13 n of NF-kappa B, AP-1, JNK, and apoptosis by HIV-tat protein but has minimal or no role in activation

14 The HIV Tat protein can be endocytosed by surrounding uninfe

15 Our results thus indicate that the HIV-tat protein can activate human vascular EC to induce

16 man histiocytic lymphoma U937 cells with the HIV-tat protein causes activation of JNK and AP-1 in a t

17 se ApiCCT1 has a region of similarity to the HIV Tat protein cell-transduction domain, we tested whet

18 We discovered that HIV-Tat protein could be transported along anatomical pa

19 glutathione peroxidase, NK-lysin/granulysin, HIV Tat protein, H(2)O(2), lipid hydroperoxides, vitamin

20 nstrated that a TAT peptide derived from the HIV TAT protein has the ability to transduce peptides or

21 The human immunodeficiency virus (HIV) Tat protein has a critical role in viral transcript

22 The human immunodeficiency virus (HIV)-Tat protein has been implicated in the neuropathoge

23 duce an elongation block that is overcome by HIV Tat protein in conjunction with P-TEFb.

24 ot only further highlights the importance of HIV Tat protein in HIV/neuroAIDS, but also presents a ne

25 nd in the activation of transcription by the HIV Tat protein in human cells.

26 r these effects, we constitutively expressed HIV-Tat protein in astrocytes.

27 We report here that the HIV Tat protein is strongly immunosuppressive, both imme

28 Treatment of primary monocytes with soluble HIV-Tat protein is associated with increased monocyte me

29 HIV-tat protein, like TNF, activates a wide variety of c

30 Human immunodeficiency virus-1 tat (HIV-tat) protein, like other proinflammatory cytokines (

31 Treatment of primary monocytes with soluble HIV-Tat protein mimicked many of the properties of HIV i

32 , we demonstrated that exposure of HUVECs to HIV Tat protein resulted in induced expression of cell a

33 n or treatment with a CRMP2 peptide fused to HIV TAT protein (TAT-CBD3) blocked neuronal death follow

34 ugated to the protein transduction domain of HIV-TAT protein (TATFLAGVHL-peptide) to facilitate entry

35 l-penetrating peptide (CPP) conjugate of the HIV TAT protein that is fused to an aminoterminal sequen

36 was fused to the polybasic sequence from the HIV Tat protein to facilitate entry into cells.

37 The conjugation of peptides derived from the HIV TAT protein to membrane-impermeant molecules has gai

38 Binding of the HIV tat protein to the TAR (transactivating response reg

39 but continues to synergize normally with the HIV Tat protein to transactivate the HIV long terminal r

40 argeted by the human immunodeficiency virus (HIV) Tat protein to activate elongation of the integrate

41 t study, we have examined the ability of the HIV-Tat protein to alter the migratory and invasive beha

42 tumor-associated Ag (OVA) that contains the HIV TAT protein transduction domain (PTD) was readily en

43 s with versions of these peptides containing HIV-Tat protein transduction and mammalian mitochondrial

44 f class IA PI3K adaptor subunit, fused to an HIV-TAT protein transduction domain (TAT-Deltap85) conce

45 on into mice of dnRas, which was fused to an HIV-TAT protein transduction domain (TAT-dnRas).

46 When fused to the HIV-TAT protein transduction domain and delivered as a p

47 ibitors of transcriptional activation by the HIV Tat protein, we used a combination of in vitro and i

48 Lipopolysaccharide (LPS) and the neurotoxic HIV Tat protein, which cause dopamine neuronal toxicity

49 HIV Tat protein, which is the transactivator of transcri