ライフサイエンスコーパス: HIV infection

1 components underlying ongoing activation in HIV infection.

2 d with bladder cancer and increased risk for HIV infection.

3 l-molecule inhibitors of LIMK for inhibiting HIV infection.

4 g unprecedented insights into the biology of HIV infection.

5 lope proteins (Envs) play a critical role in HIV infection.

6 revent disease progression, it does not cure HIV infection.

7 o optimize clinical outcomes in persons with HIV infection.

8 cells in response to TCR stimulation and/or HIV infection.

9 s one of the earliest pathological events in HIV infection.

10 with men, particularly those with coexistent HIV infection.

11 advances in the prevention and treatment of HIV infection.

12 ing host immune homeostasis with and without HIV infection.

13 PrEP over 48 weeks in U.S. women at risk for HIV infection.

14 molecules inside the target cell that fight HIV infection.

15 or differentiation as well as for productive HIV infection.

16 ed approaches to treatment and prevention of HIV infection.

17 stable correlates of protection from initial HIV infection.

18 sent during pathogenic conditions, including HIV infection.

19 terest in using antibodies to treat and cure HIV infection.

20 nfected with HIV, and 283 were controls with HIV infection.

21 se by women at substantial risk of acquiring HIV infection.

22 development of lung cancer in the setting of HIV infection.

23 hieve greater reductions in the incidence of HIV infection.

24 in ECs than in subjects with typical chronic HIV infection.

25 test (Alere HIV Combo) for the diagnosis of HIV infection.

26 or IFN-I blockade as a potential therapy for HIV infection.

27 rus replication in a murine model of chronic HIV infection.

28 ietic stem cells in conferring resistance to HIV infection.

29 as new NNRTIs for the potential treatment of HIV infection.

30 r their incorporation into the management of HIV infection.

31 s mediate long-range GJ communication during HIV infection.

32 n models to identify correlates of prevalent HIV infection.

33 mong participants without hepatitis C and/or HIV infection.

34 ident a suspected exposure did not result in HIV infection.

35 have a major contribution to host control of HIV infection.

36 e used to eliminate persistent reservoirs of HIV infection.

37 nts, and was more frequent among people with HIV infection.

38 neuropathy is a neurological complication of HIV infection.

39 SF characteristics, compared with absence of HIV infection.

40 istant variants in participants with chronic HIV infection.

41 te relationships between gender identity and HIV infection.

42 ormalities in brain structure in relation to HIV infection.

43 losis immunity at the site of disease during HIV infection.

44 min quotient (QAlb) in patients with primary HIV infection.

45 t of excess adiposity in adults with treated HIV infection.

46 cells and eradicate persistent reservoirs of HIV infection.

47 production and immune activation in chronic HIV infection.

48 ssociated with both human papillomavirus and HIV infection.

49 y place them at a particularly high risk for HIV infection.

50 It is not yet possible to cure HIV infection.

51 -dimer, and HA levels were elevated in acute HIV infection.

52 in part, on their perceived risk of incident HIV infection.

53 ion and is a central obstacle to the cure of HIV infection.

54 ctivate CD4(+) T cells, the target cells for HIV infection.

55 ongitudinal observational studies of primary HIV infection.

56 ipants were not necessarily at high risk for HIV infection.

57 ong three case-control sets of children with HIV infection.

58 learance strategies to eradicate established HIV infection.

59 (9.8) years, 97.0% were male, and 32.2% had HIV infection.

60 e-exposure prophylaxis for the prevention of HIV infection.

61 cs against CNS complications associated with HIV infection.

62 rovirals for use in therapy or prevention of HIV infection.

63 ell as the presence of disability-associated HIV infection.

64 of Gag peptides in the long-term control of HIV infection.

65 ancy to achieve the elimination of pediatric HIV infections.

66 nd to identify predictors of newly diagnosed HIV infections.

67 acquisition of human immunodeficiency virus (HIV) infection.

68 dividuals with human immunodeficiency virus (HIV) infection.

69 rue in chronic human immunodeficiency virus (HIV) infection.

70 d mortality in human immunodeficiency virus (HIV) infection.

71 patients with human immunodeficiency virus (HIV) infection.

72 lth effects of human immunodeficiency virus (HIV) infection.

73 mian (SIV) and human immunodeficiency virus (HIV) infections.

74 s than 1% reported ever being diagnosed with HIV infection (0.9%, 95% CI 0.4-2.5) and initiated antir

75 es not infected with HIV, 75 were cases with HIV infection, 1118 were controls not infected with HIV,

76 Five participants acquired HIV infection (4 MVC alone, 1 MVC + TDF; overall annuali

77 ( pound1.0 billion discounted), avert 25% of HIV infections (42% of which would be directly because o

78 ngs suggest that within the first year after HIV infection, a relatively weak neutralizing antibody r

79 HIV infection affects 37 million people and about 1.7 mi

80 or sustain disparities in the prevalence of HIV infection, alone or in conjunction with scenarios of

81 rtant to immune control of HIV.IMPORTANCE In HIV infection, although cytotoxic T lymphocytes (CTL) pl

82 for live births, the incidence of perinatal HIV infection among infants born in the United States in

83 study of the natural and treated history of HIV infection among men who have sex with men in the USA

84 he change in community burden of undiagnosed HIV infection among older children and adolescents follo

85 e strongly associated with increased risk of HIV infection among participants with disabilities but n

86 ere syringe sharing (n=35) and prevalence of HIV infection among PWID (n=28).

87 ll as psychosocial and behavioral drivers of HIV infection among transgender women compared with cisg

88 an outbreak of human immunodeficiency virus (HIV) infection among persons who inject drugs (PWID) in

89 hest burden of human immunodeficiency virus (HIV) infection among US women.

90 of undiagnosed human immunodeficiency virus (HIV) infections among persons who inject drugs (PWID) wa

91 Results Among 447,953 people with HIV infection, anal cancer incidence was much higher tha

92 of whom 2,325 (57.4%) were unaware of their HIV infection and 2,816 (69.5%) were HIV viremic.

93 n which individuals presented with untreated HIV infection and active pulmonary TB.

94 be an important resource for information on HIV infection and AIDS.

95 Maternal HIV infection and antiretroviral medication, including m

96 n to its direct morbidity, increases risk of HIV infection and can cause lifelong morbidity in childr

97 ghlight the epidemiological evidence linking HIV infection and CHD.

98 the pathogenesis and factors associated with HIV infection and CHD.

99 athia, and other anaerobes) inflammation and HIV infection and found that high-risk bacteria increase

100 vasive pneumococcal disease in children with HIV infection and in those not infected with HIV.

101 than non-users, the direct impact of METH on HIV infection and its link to the development of neuroco

102 Given the HIV infection and malaria coepidemic in sub-Saharan Afri

103 HIV infection and mortality did not differ significantly

104 ARV) and progestin contraceptives to prevent HIV infection and pregnancy.

105 Our findings indicate that HIV infection and replication rely on a limited set of h

106 e I interferon (IFN) is induced early during HIV infection and that type I IFN-associated gene signat

107 nv identified in our work seem to facilitate HIV infection and therefore may constitute a new therape

108 be preferred to avoid missing cases of acute HIV infection and to decrease the related risks of viral

109 ence, patients present to care with advanced HIV infection and with a low CD4 cell count or re-presen

110 HIV infection and young age were associated with increas

111 e collected from local youth at high risk of HIV infection and, specifically, sexual minority males o

112 p may help to design better analogs to treat HIV infections and other diseases.

113 mon in treated human immunodeficiency virus (HIV) infection and contribute to morbidity and mortality

114 prevalence of human immunodeficiency virus (HIV) infection and pulmonary tuberculosis (PTB).

115 ssues are major primary target cells for SIV/HIV infection, and massive depletion of these cells is c

116 e is highly effective against acquisition of HIV infection, and only two cases of infection with a mu

117 criteria (ie, brain metastases, minimum age, HIV infection, and organ dysfunction and prior and concu

118 b induction and maturation in the setting of HIV infection, and point to key roles for both central a

119 e associated with poorer cognitive function, HIV infection, and systemic immune activation.

120 APOL1 renal risk variants in the context of HIV infection, antiretroviral therapy-related nephrotoxi

121 Persons with HIV infection are at increased risk for hepatitis B viru

122 ld be sustainable in the context of vertical HIV infection as repeated testing would not be necessary

123 ralizing antibodies in the immune control of HIV infection as well as for the development of effectiv

124 t disabilities reflects a higher exposure to HIV infection as well as the presence of disability-asso

125 The QAlb rises during primary HIV infection, associates with neuronal injury, and does

126 ns can confer protection in animal models of HIV infection at modest concentrations, inspiring effort

127 costs (in 2015 US dollars), health outcomes (HIV infections averted, change in HIV prevalence, and di

128 pheresis from a 55-year-old man with chronic HIV infection before and after allo-SCT to measure the s

129 42 women were diagnosed with acute HIV infection between Dec 1, 2012, and June 30, 2016, (i

130 s the abnormalities in B cells that occur in HIV infection both in the peripheral blood and lymphoid

131 line of iNKT cells is associated with age or HIV infection, both situations associated with HHV-8-rel

132 ine has identified host factors required for HIV infection but dispensable for cellular survival.

133 In contrast, HIV infection but not frailty was associated with signif

134 loss occurs in human immunodeficiency virus (HIV) infection but paradoxically is intensified by HIV-a

135 -specific CD4+ T cells in blood during early HIV infection, but little is known about responses in th

136 ceptors augments CD8 T cell functionality in HIV infection, but their influence on CD4 T cells remain

137 for preventing human immunodeficiency virus (HIV) infection, but risk compensation (RC) in men who ha

138 ong women with human immunodeficiency virus (HIV) infection, but whether the risk differs by ART regi

139 irus (HCV) and human immunodeficiency virus (HIV) infections, but the independent contributions of HC

140 BNAbs are made during HIV infection by a subset of individuals but currently c

141 This protein plays a key role in HIV infection by facilitating the nuclear import of the

142 ve constructed a model of the recognition of HIV infection by the MHC class I pathway.

143 We assessed predictors of newly diagnosed HIV infections by comparing newly diagnosed with HIV-neg

144 during primary human immunodeficiency virus (HIV) infection by evaluating the cerebrospinal fluid (CS

145 n the USA, we examined the effect of ageing, HIV infection (by disease stage), and their interaction

146 o reduce leukocyte mobilization during early HIV infection, can provide prolonged neuroprotection, wh

147 ith HIV and six controls for every case with HIV infection (case-control sets).

148 In seronegative acute HIV infection, CD8(+) T cell counts increased in the epi

149 Nevertheless, in individuals with aTB and/or HIV infection, circulating ex vivo M. tuberculosis-speci

150 Microbiome diversity was reduced in treated HIV infection compared to HIV SN (p < 0.05).

151 Development of vaccines for HIV infection continues to provide insight into the immu

152 As part of the HIV infection cycle, viral DNA inserts into the genome o

153 syringes, and the proportion of undiagnosed HIV infection declined from 84.3% to 15.0% (P < .001).

154 In this longitudinal study, the incidence of HIV infection declined significantly with the scale-up o

155 A total of 236 (37.5%) of the mothers had HIV infection diagnosed before pregnancy in 2002-2005 co

156 o blockade of IFN-I signaling during chronic HIV infection diminished HIV-driven immune activation, d

157 Chronic HIV infection due to effective antiretroviral treatment

158 dence is markedly elevated among people with HIV infection, especially in MSM, older individuals, and

159 ents with co-infection (hepatitis B virus or HIV infection), evidence of decompensated liver disease,

160 h condomless receptive anal sex, the odds of HIV infection for transgender women were 2.2 times great

161 the course of Human Immunodeficiency Virus (HIV) infection from an almost universally fatal disease

162 By 2016, the mean incidence of HIV infection had declined by 42% relative to the period

163 The search for a cure for HIV infection has highlighted the need for increasingly

164 ease (CHD) and human immunodeficiency virus (HIV) infection has been well recognized for many years.

165 hich the TIGIT/CD226/PVR-axis is affected by HIV-infection has not been characterized.

166 Individuals with HIV infection have a 1.5 to 2 times higher incidence of

167 Animal models of HIV infection have a strong and well-documented history

168 Purpose People with HIV infection have an elevated risk of anal cancer.

169 uscript, we demonstrate that TNTs induced by HIV infection have functional GJs at the ends of their m

170 ong U.S. patients receiving medical care for HIV infection ("HIV patients").

171 he participants' history of tuberculosis and HIV infection, hospitalizations, and social networks.

172 In human immunodeficiency virus (HIV) infection, host factors, HIV-specific variables, an

173 als, although the precise mechanisms whereby HIV infection impedes successful T cell-mediated control

174 8(+) T cells in elite controllers to inhibit HIV infection.IMPORTANCE The greater ex vivo antiviral i

175 rus-specific CD8 T cells with progression of HIV infection in humans and during chronic lymphocytic c

176 Diagnosis of perinatally acquired HIV infection in infants born in the United States.

177 verall, p21 appears to be a key regulator of HIV infection in myeloid cells.

178 tionship between the processes of ageing and HIV infection in neurocognitive impairment.

179 INTERPRETATION: The higher prevalence of HIV infection in people with disabilities than people wi

180 abeys or mandrills (SIVrcm/mnd-2), increased HIV infection in resting CD4 T cells, but not in macroph

181 intrahost evolutionary patterns during human HIV infection in the absence of antiretroviral therapy.

182 e associated with reduced risk of peripartum HIV infection in the historic U.S. Woman and Infant Tran

183 counted for 687 (38.0%) of infants born with HIV infection in the United States during the overall pe

184 Despite reduced perinatal HIV infection in the United States, missed opportunities

185 fusion to target cells, and also facilitates HIV infection in various indirect ways.

186 g women detected during Fiebig stage I acute HIV infection in whom treatment was initiated immediatel

187 Furthermore, we assessed to which extent HIV infection in women is associated with maternal recto

188 The incidence of HIV infection in young women in Africa is very high.

189 the source and consequences of high rates of HIV infection in young women in South Africa.

190 The rate of new HIV infections in high-prevalence settings in Africa rem

191 ge to care among sex partners of people with HIV infections in Kenya.

192 Although the annual number of new HIV infections in Sub-Saharan Africa has decreased latel

193 Sub-Saharan Africa has decreased lately, new HIV infections in the Middle East and North Africa regio

194 Factors positively associated with HIV infection included being aged 21-30 years and report

195 be a consideration in treatment choices for HIV infection, including the choices of antiretroviral r

196 Overall, we propose that HIV infection increases Cx43 expression in heart, result

197 To investigate whether HIV infection increases the risk of future HFrEF and HFp

198 ecognized that human immunodeficiency virus (HIV) infection increases the risk of developing TB, but

199 HIV infection independently predicted death due to TBM (

200 HIV infection induces remarkable expansion of CD8(+)CD28

201 HIV infection induces significant chronic immune activat

202 LTA4H genotype and HIV infection influence pretreatment inflammatory phenot

203 In chronic HIV infection, inhibitory receptor distribution differed

204 s in antiretroviral therapy have transformed HIV infection into a chronic condition.

205 ted partner services for index patients with HIV infections involves elicitation of information about

206 Ts) used for early infant diagnosis (EID) of HIV infection is <100%, leading some HIV-uninfected infa

207 ment of an efficient vaccine able to prevent HIV infection is a worldwide priority.

208 Determining whether HIV infection is associated with HF with reduced ejectio

209 In the large majority of cases, HIV infection is established by a single variant, and un

210 HIV infection is limited to these G1-like phase macropha

211 Enteropathy in HIV infection is not eliminated with combination antiret

212 chronic human immunodeficiency virus type 1 (HIV) infection is a key mechanism that leads to the deve

213 Human immunodeficiency virus (HIV) infection is a recognized risk factor for stroke am

214 trol of human immunodeficiency virus type 1 (HIV) infection is typically associated with effective Ga

215 nalysis can estimate the probable country of HIV infection, it can help to inform the design of publi

216 for a functional cure or the eradication of HIV infection, it is necessary to know the sizes of the

217 HIV infection itself should no longer be an exclusion cr

218 HIV infection may be an important factor for this increa

219 , suggesting that its down-regulation during HIV infection may be part of an anti-viral host response

220 and the relationships to viral load in acute HIV infection, measurements of the latent reservoir in c

221 lb was elevated in 106 patients with primary HIV infection (median time of measurement, 91 days after

222 nalysis and the resulting data regarding how HIV infection might change the balance of commensal bact

223 HIV-specific Abs and Abs produced in natural HIV infection modulated normal pDC sensing of HIV.

224 In human immunodeficiency virus (HIV) infection, naturally induced cell-mediated immune r

225 c steatosis in human immunodeficiency virus (HIV) infection need to be identified.

226 MK1) with short hairpin RNA (shRNA) inhibits HIV infection, no specific small-molecule inhibitor of L

227 ation.IMPORTANCE More than 150,000 pediatric HIV infections occur yearly, despite the availability of

228 No new HIV infections occurred, although whether this was due t

229 No new HIV infections occurred.

230 Incident HIV infection of chronically HCV infected subjects resul

231 and nonfunctional Envs contributes little to HIV infection of human lymphoid tissue ex vivo.

232 Here, we demonstrate that while acute HIV infection of human microglia/macrophages results in

233 ent study, we hypothesized that METH impacts HIV infection of neural progenitor cells (NPCs) by a mec

234 myeloid-only mice (MoM), we demonstrate that HIV infection of tissue macrophages is rapidly suppresse

235 We evaluated the effect of maternal HIV infection on transplacental antibody transfer specif

236 or anal intercourse with at least 1 man with HIV infection or unknown serostatus within 90 days.

237 l transduction and autophagy in single-round HIV infection or with nonreplicative HIV-1-derived lenti

238 diac Complications of Vertically Transmitted HIV Infection (P(2)C(2) HIV) study.

239 METHODS AND People with and without HIV infection participating in HSV-2 natural history stu

240 In chronic diseases, such as HIV infection, plasmacytoid dendritic cells (pDCs) are r

241 This suggests that HIV infection plays a role in liver inflammation.

242 f ART at one of the earliest stages of acute HIV infection possible.

243 Human immunodeficiency virus (HIV) infection, present in 15.3% of patients, was associ

244 se progression to AIDS in infants.IMPORTANCE HIV infection progresses much more rapidly in pediatric

245 d may reduce viral reservoirs during chronic HIV infection, providing validation for IFN-I blockade a

246 The main model outcomes were the number of HIV infections, quality-adjusted life-years (QALYs), and

247 -five patients with stage I to III SCCAC and HIV infection received CRT: 45 to 54 Gy radiation therap

248 of brain structure abnormalities in treated HIV infection remain to be identified.

249 As of 2013, the incidence of perinatal HIV infection remained 1.75 times the proposed Centers f

250 uence on CD4 T cell functionality in chronic HIV infection remains poorly described.

251 Cure of Human Immunodeficiency Virus (HIV) infection remains elusive due to the persistence of

252 HIV DNA-containing cells.IMPORTANCE Cure of HIV infection requires an intervention that reduces the

253 Blocking or reducing GJ communication during HIV infection resulted in aberrant TNT cell-to-cell cont

254 dividuals with human immunodeficiency virus (HIV) infection, resulting in death in approximately 40%

255 esistant to nucleoside analogs used to treat HIV infections reveal that the ground state binding is w

256 e members with human immunodeficiency virus (HIV) infection revealed 19 (18.6%) cases of M. genitaliu

257 tive tract (FRT) is hypothesized to increase HIV infection risk by interfering with barrier protectio

258 , even among US black women at high risk for HIV infection, sample size requirements for an RCT with

259 usceptibility of people with disabilities to HIV infection seems to be shaped by social and environme

260 Older individuals with HIV infection should be targeted for regular screening f

261 duodenum were studied at different stages of HIV infection, starting from the seronegative phase.

262 There was no significant association between HIV infection status and rectovaginal GBS carriage.

263 face the challenge of disclosure of parental HIV infection status.

264 Human immunodeficiency virus type 1 (HIV) infection substantially increases the risk of devel

265 y and motor function with advanced stages of HIV infection suggests that these two domains are most s

266 To be considered for HCT, patients must have HIV infection that is responsive to combination antiretr

267 5, among 573 ART-naive PWUD (18% with recent HIV infection), the overall TDR prevalence was 9.8% (95%

268 During primary HIV infection, the presence of minority drug resistance

269 with advanced human immunodeficiency virus (HIV) infection, the rate of death from infection (includ

270 Of the 404 participants, 311 (77%) had HIV infection; the median CD4+ count was 340 cells per c

271 r already in the seronegative phase of acute HIV infection, thereby inducing microbial translocation

272 HCV infected subjects who developed incident HIV infection to determine if IL-18 increases with coinf

273 ne resistance testing early in the course of HIV infection to guide ART selection among PWUD in our s

274 isease (including hemodialysis patients), or HIV infection; travelers to HBV-endemic regions; and adu

275 integration of fungal diseases into existing HIV infection, tuberculosis infection, diabetes, chronic

276 inistered by injection that prevented simian-HIV infection upon repeat intrarectal challenge in male

277 HIV infection upsets the delicate balance in the normal

278 ll detection rate of people unaware of their HIV infection was 0.5 persons per day, and the detection

279 Maternal HIV infection was also associated with reduced transplac

280 R3(+)CCR6(+)CCR4(-) (Th1*) phenotype, aTB or HIV infection was associated with a contraction of this

281 HIV infection was associated with a lower total frequenc

282 Moreover, HIV infection was associated with increased M. tuberculo

283 ART initiated in early acute HIV infection was associated with normalization of the c

284 In these middle-aged individuals, HIV infection was independently associated with renal im

285 HIV infection was not associated with mortality (HR: 3.0

286 weeks of age, or until weaning occurred and HIV infection was ruled out.

287 New HIV infection was significantly more prevalent among His

288 nodeficiency virus (HIV) on the incidence of HIV infection, we analyzed the association between the i

289 CD4(+) T cell memory inflation occurs during HIV infection, we used HLA-DR7 (DRB1*07:01) tetramers lo

290 eir HIV status, 90% of people with diagnosed HIV infection will receive antiretroviral treatment (ART

291 tedly, but effective depletion of persistent HIV infection will require additional advances.

292 ared with uninfected individuals, those with HIV infection with a recent biomarker of more severe imm

293 compare anal cancer incidence in people with HIV infection with the general population, used Poisson

294 losis deaths worldwide were in children with HIV infections, with 31 000 (36%, 19 000-59 000) in the

295 as this subtype accounts for the majority of HIV infections worldwide, but well-ordered clade C Env t

296 C, which is responsible for the majority of HIV infections worldwide.

297 berculosis and human immunodeficiency virus (HIV) infection worldwide.

298 etermine whether ART initiation during acute HIV infection would attenuate changes in these biomarker

299 eceptors CD4 and CCR5, that are required for HIV infection yet are dispensable for cellular prolifera

300 sion, and T cell exhaustion are hallmarks of HIV infection, yet the mechanisms driving these processe