ライフサイエンスコーパス: Histoplasma capsulatum

1 lution of infection with the fungal pathogen Histoplasma capsulatum.

2 ith class 5 or 6 organisms than with class 2 Histoplasma capsulatum.

3 omoters of two yeast phase-specific genes in Histoplasma capsulatum.

4 nt of heat shock protein 60 from the fungus, Histoplasma capsulatum.

5 e during primary infection with the pathogen Histoplasma capsulatum.

6 fungal nitric oxide reductase (P450nor) from Histoplasma capsulatum.

7 of both primary and secondary infection with Histoplasma capsulatum.

8 ular genetic studies of the dimorphic fungus Histoplasma capsulatum.

9 sponse against Mycobacterium tuberculosis or Histoplasma capsulatum.

10 are essential for controlling infection with Histoplasma capsulatum.

11 inst many intracellular infections including Histoplasma capsulatum.

12 ell as to the natural CR3 ligands, iC3b, and Histoplasma capsulatum.

13 laboratory evidence of recent infection with Histoplasma capsulatum.

14 recombinant (r) hsp60 protects mice against Histoplasma capsulatum.

15 ith recognition of the worldwide presence of Histoplasma capsulatum.

16 TNF-alpha in CCR5(-/)(-) mice infected with Histoplasma capsulatum.

17 is) infected with the intracellular pathogen Histoplasma capsulatum.

18 charomyces cerevisiae, Candida albicans, and Histoplasma capsulatum.

19 tope in Blastomyces dermatitidis and also in Histoplasma capsulatum.

20 R5 during infection with the fungal pathogen Histoplasma capsulatum.

21 eople harbor latent infections of the fungus Histoplasma capsulatum.

22 control of infection by the dimorphic fungus Histoplasma capsulatum.

23 e human pathogens Coccidioides posadasii and Histoplasma capsulatum.

24 tective immunity in an Ag-specific manner to Histoplasma capsulatum.

25 elevated in the lungs of mice infected with Histoplasma capsulatum.

26 sis influenced host resistance to the fungus Histoplasma capsulatum.

27 role of these agents in host defense against Histoplasma capsulatum.

28 influenced protective and memory immunity to Histoplasma capsulatum.

29 these genes in vivo, mice were infected with Histoplasma capsulatum.

30 ve domain (F3) of heat-shock protein 60 from Histoplasma capsulatum.

31 ion in the lungs of naive mice infected with Histoplasma capsulatum.

32 A monoclonal antibody (MAb) raised against a Histoplasma capsulatum 80-kDa hsp showed cross-reactivit

33 dermatitidis an extracellular pathogen, and Histoplasma capsulatum a facultative intracellular patho

34 Histoplasma capsulatum, a fungal pathogen of humans, swi

35 D-1 in a mouse model of acute infection with Histoplasma capsulatum, a major human pathogenic fungus.

36 CBP is the most abundant protein secreted by Histoplasma capsulatum, a pathogenic fungus that causes

37 We describe a case in which the Histoplasma capsulatum AccuProbe test displayed cross-re

38 We demonstrated the ability of the Histoplasma capsulatum AccuProbe to accurately identify

39 ffers from the epitopes that are shared with Histoplasma capsulatum and Blastomyces dermatitidis.

40 it exerts potent antifungal activity against Histoplasma capsulatum and Cryptococcus neoformans by di

41 f microarrays built with genomic elements of Histoplasma capsulatum and ESTs of Paracoccidioides bras

42 ular evidence suggests a direct link between Histoplasma capsulatum and presumed ocular histoplasmosi

43 nsformation system for the pathogenic fungus Histoplasma capsulatum and used it to examine the effect

44 nt Candida species, Cryptococcus neoformans, Histoplasma capsulatum, and Blastomyces dermatitidis fro

45 ns in North America (Coccidioides posadasii, Histoplasma capsulatum, and Blastomyces dermatitidis), h

46 For the fungus Histoplasma capsulatum, and for other microbial pathogen

47 DCs) with Leishmania donovani promastigotes, Histoplasma capsulatum, and Mycobacterium kansasii impai

48 Rhizopus arrhizus, Blastomyces dermatitidis, Histoplasma capsulatum, and Sporothrix schenckii.

49 s in the lungs of C57BL/6 mice infected with Histoplasma capsulatum, and the elimination of these cel

50 egative for C. immitis, B. dermatitidis, and Histoplasma capsulatum antibodies.

51 Paracoccidioides brasiliensis and Histoplasma capsulatum are ancestral to most Emmonsia is

52 Blastomyces dermatitidis and Histoplasma capsulatum are dimorphic fungi that often ca

53 Improved methods for the detection of Histoplasma capsulatum are needed in regions with limite

54 rmally dimorphic fungal pathogens, including Histoplasma capsulatum, are soil fungi that undergo dram

55 The success of Histoplasma capsulatum as an intracellular pathogen depe

56 nction of HIF-1alpha in the host response to Histoplasma capsulatum because granulomas induced by thi

57 ribosomal DNA, were used to amplify DNA from Histoplasma capsulatum, Blastomyces dermatitidis, Coccid

58 Fourteen samples grew Histoplasma capsulatum; both systems detected H. capsula

59 r to a triglycosyl IPC (Hc-VI) reported from Histoplasma capsulatum, but differing in the anomeric co

60 nses against intracellular pathogens such as Histoplasma capsulatum, but its mode of action remains e

61 Histoplasma capsulatum can efficiently survive within ma

62 molecular cloning and characterization of a Histoplasma capsulatum cDNA (GH17) that encodes an antig

63 Except with Histoplasma capsulatum, chocolate agar incubated for onl

64 y significant episodes, the isolated fungus (Histoplasma capsulatum, Coccidioides immitis/posadasii,

65 The endemic fungi Histoplasma capsulatum, Coccidioides spp, Blastomyces de

66 esented with a Mycobacterium haemophilum and Histoplasma capsulatum coinfection occurring 21 years af

67 ported that immunization with H antigen from Histoplasma capsulatum did not protect mice against an i

68 The fungus Histoplasma capsulatum displays an Hsp60 on its cell sur

69 dentified a secreted proteolytic activity in Histoplasma capsulatum effective toward DppIV-specific s

70 The YPS3 gene of Histoplasma capsulatum encodes a protein that is both su

71 We report a case of Histoplasma capsulatum endocarditis in which Histoplasma

72 The pathogenic fungus Histoplasma capsulatum escapes innate immune defenses an

73 The fungal pathogen Histoplasma capsulatum evades the innate and adaptive im

74 1990 through 1994, we fortuitously isolated Histoplasma capsulatum from six patients with AIDS whose

75 regulatory T cells (Tregs) using a model of Histoplasma capsulatum fungal infection.

76 library representing 10-fold coverage of the Histoplasma capsulatum G217B genome was used to construc

77 Here, we detail mapping the Histoplasma capsulatum genome comprehensively in fosmids

78 The human fungal pathogen Histoplasma capsulatum grows in a sporulating filamentou

79 The Histoplasma capsulatum H antigen is a major secreted gly

80 ponse to the intracellular pathogenic fungus Histoplasma capsulatum has increased dramatically.

81 Histoplasma capsulatum has not typically been associated

82 human fungal pathogens Candida albicans and Histoplasma capsulatum have been reported to protect aga

83 Ten cases of Histoplasma capsulatum (HC) infection were reported: 9 a

84 Histoplasma capsulatum (Hc) is a facultative intracellul

85 Histoplasma capsulatum (Hc) is a facultative intracellul

86 Histoplasma capsulatum (Hc) is a facultative, intracellu

87 Histoplasma capsulatum (Hc) is a pathogenic fungus that

88 rimary and secondary infection by the fungus Histoplasma capsulatum (HC) is multifactorial, requiring

89 Histoplasma capsulatum (Hc) maintains a phagosomal pH of

90 The intracellular fungal pathogen Histoplasma capsulatum (Hc) resides in mammalian macroph

91 genic fungi Cryptococcus neoformans (CN) and Histoplasma capsulatum (HC) to external gamma-radiation

92 ix proteins, and the intracellular growth of Histoplasma capsulatum (Hc) yeasts were quantified and c

93 e deficient in their capacity to phagocytose Histoplasma capsulatum (Hc) yeasts, and are more permiss

94 Histoplasma capsulatum (Hc), is a facultative intracellu

95 imary and secondary pulmonary infection with Histoplasma capsulatum (Hc).

96 r host defense against the pathogenic fungus Histoplasma capsulatum (Hc).

97 ), Cryptococcus neoformans (cryptococcosis), Histoplasma capsulatum (histoplasmosis), and Talaromyces

98 In other fungi, such as Histoplasma capsulatum, however, more efficient gene dis

99 A real-time PCR assay to detect Histoplasma capsulatum in formalin-fixed, paraffin-embed

100 e examined the immunobiological responses to Histoplasma capsulatum in lungs of gamma interferon (IFN

101 n-4 impairs clearance of the fungal pathogen Histoplasma capsulatum in mice lacking the chemokine rec

102 Histoplasma capsulatum induces a cell-mediated immune re

103 Histoplasma capsulatum induces a cell-mediated immune re

104 tion with heat shock protein 60 (Hsp60) from Histoplasma capsulatum induces a protective immune respo

105 Rising rates of Histoplasma capsulatum infection are an emerging problem

106 emonstrate that CCR5 controls the outcome of Histoplasma capsulatum infection by dictating thymic and

107 mmalian host specifically limits iron during Histoplasma capsulatum infection, and fungal acquisition

108 B6C3F(1) mice were infected by injection of Histoplasma capsulatum into the subarachnoid space.

109 Histoplasma capsulatum is a dimorphic fungal pathogen th

110 Histoplasma capsulatum is a dimorphic fungus that causes

111 Histoplasma capsulatum is a dimorphic fungus that is end

112 Histoplasma capsulatum is a fungal pathogen that causes

113 Histoplasma capsulatum is a fungal pathogen that require

114 Histoplasma capsulatum is a fungal respiratory pathogen

115 Histoplasma capsulatum is a pathogenic fungus that exist

116 Histoplasma capsulatum is a pathogenic fungus with two d

117 Histoplasma capsulatum is a respiratory pathogen that in

118 Histoplasma capsulatum is a significant respiratory and

119 Histoplasma capsulatum is a successful intracellular pat

120 Histoplasma capsulatum is an effective intracellular par

121 Histoplasma capsulatum is an infrequent but serious caus

122 cell-depleted mice infected with the fungus Histoplasma capsulatum is associated with impairment of

123 A fundamental feature of the fungal pathogen Histoplasma capsulatum is its ability to shift from a my

124 Histoplasma capsulatum is the best-studied of the primar

125 the pathogenesis of the respiratory pathogen Histoplasma capsulatum is the conversion from the mold f

126 Histoplasma capsulatum is the most common cause of funga

127 The yeast phase of Histoplasma capsulatum is the virulent form of this ther

128 The phylogeny of 46 geographically diverse Histoplasma capsulatum isolates representing the three v

129 Although more Histoplasma capsulatum isolates were recovered from Plus

130 The zoopathogenic fungus Histoplasma capsulatum, like other eukaryotic aerobic mi

131 ients with deficient cell-mediated immunity, Histoplasma capsulatum may disseminate throughout the bo

132 uconazole (Flu) and amphotericin B (AmB) for Histoplasma capsulatum meningitis, MICs were determined

133 The fungal pathogen Histoplasma capsulatum minimizes detection of beta-gluca

134 ronment in which the primary fungal pathogen Histoplasma capsulatum multiplies and disseminates from

135 Primary infection to Histoplasma capsulatum often results in a self-limited u

136 ve with IS only (three Candida albicans, one Histoplasma capsulatum, one Candida glabrata, and one Fu

137 tion of mice with heat shock protein 60 from Histoplasma capsulatum or a polypeptide from the protein

138 ombinant heat shock protein 60 (rHsp60) from Histoplasma capsulatum or a region of the protein design

139 statistically significantly more isolates of Histoplasma capsulatum (P = 0.004), but all of these iso

140 ntiana, Fusarium oxysporum, Fusarium solani, Histoplasma capsulatum, Phialophora spp., Pseudallescher

141 sis, a systemic mycosis caused by the fungus Histoplasma capsulatum, primarily affects immune-suppres

142 The fungus, Histoplasma capsulatum, produces a persistent infection.

143 Host defenses against Histoplasma capsulatum require the action of several cyt

144 The pathogenic fungus Histoplasma capsulatum requires iron for its survival du

145 Protection against the pathogenic fungus Histoplasma capsulatum requires Th1 cytokines.

146 Infection with Histoplasma capsulatum results in a subclinical infectio

147 bility to bind calcium and its prevalence as Histoplasma capsulatum's most abundant secreted protein.

148 Histoplasma capsulatum should be considered in the diffe

149 ct several general DNA binding proteins from Histoplasma capsulatum strain G217B.

150 , yps-3, has been identified in the virulent Histoplasma capsulatum strain, G217B.

151 Many Histoplasma capsulatum strains have alpha-(1,3)-glucan i

152 Many Histoplasma capsulatum strains spontaneously give rise t

153 parasite of macrophages, the yeast phase of Histoplasma capsulatum, survives and proliferates within

154 For the dimorphic fungal pathogen Histoplasma capsulatum, susceptibility to echinocandins

155 FM) is a rare complication of infection with Histoplasma capsulatum that can lead to obstruction of p

156 are consequence of infection with the fungus Histoplasma capsulatum that can lead to occlusion of lar

157 tested a real-time LightCycler PCR assay for Histoplasma capsulatum that correctly identified the 34

158 ermatitidis, the agent of blastomycosis, and Histoplasma capsulatum, the agent of histoplasmosis, are

159 xpressed the gene encoding this protein from Histoplasma capsulatum to study its immunological activi

160 h chitin, in patterns ranging from circular (Histoplasma capsulatum) to punctate (Cryptococcus neofor

161 We cloned the Histoplasma capsulatum URA5 gene (URA5Hc) by using a pro

162 The Histoplasma capsulatum URA5 gene, which has recently bee

163 Detection of the Histoplasma capsulatum urinary antigen (UAg) is among th

164 be of limited use, whereas the detection of Histoplasma capsulatum var. capsulatum antigens may prov

165 We studied an aberrant culture of Histoplasma capsulatum var. capsulatum isolated from syn

166 ther the thermally dimorphic fungal pathogen Histoplasma capsulatum var. capsulatum produced melanin

167 Histoplasma capsulatum var. farciminosum, the causative

168 A sample of 30 clinical isolates of Histoplasma capsulatum was analyzed to determine (i) whe

169 nd ploidy of the dimorphic pathogenic fungus Histoplasma capsulatum was determined by using DNA renat

170 e H antigen of the dimorphic fungal pathogen Histoplasma capsulatum was first described over 40 years

171 )-alpha after intranasal exposure of mice to Histoplasma capsulatum was necessary for control of prim

172 irulence mutants of Francisella novicida and Histoplasma capsulatum, we confirmed the applicability o

173 yces dermatitidis, Sporothrix schenckii, and Histoplasma capsulatum were each ingested by amoebae and

174 ITS) regions of rRNA genes of 24 isolates of Histoplasma capsulatum were examined.

175 Two isolates of Histoplasma capsulatum were recovered from the Isolator

176 esii; and a more diverged pathogenic fungus, Histoplasma capsulatum, were sequenced and compared with

177 t (Y) phase of the dimorphic fungal pathogen Histoplasma capsulatum which are transcriptionally silen

178 ts with disseminated Coccidioides immitis or Histoplasma capsulatum with heterozygous missense mutati

179 can is present in the outermost layer of the Histoplasma capsulatum yeast cell wall and contributes t

180 potent and long-lasting fungistasis against Histoplasma capsulatum yeasts and that all of the fungis

181 During infection of the mammalian host, Histoplasma capsulatum yeasts survive and reside within