ライフサイエンスコーパス: ICA

1 ICA and heat map suggest four components best describe t

2 ICA identified three DMNs.

3 ICA infusions of hypertonic NaCl and mannitol each signi

4 ICA is a mixed agonist of mutant EAG and EAG/ERG chimera

5 ICA is then applied to multi-scale gene clusters to reve

6 ICA of group resting-state functional MR imaging data re

7 ICA z images of DMN components were compared between the

8 ICA-105574 (ICA, or 3-nitro-N-[4-phenoxyphenyl]-benzamid

9 ICA-27243 (1-10 microM) was found to reversibly suppress

10 ICA-27243 enhanced both (86)Rb(+) efflux (EC(50) = 0.2 m

11 00-fold selectivity for human Nav1.3/Nav1.1 (ICA-121431, IC50, 19 nM) or Nav1.7 (PF-04856264, IC50, 2

12 o-n-(4-phenoxyphenyl) benzamide [ICA-105574 (ICA)] has been discovered to activate hERG1 by strong at

13 ICA-105574 (ICA, or 3-nitro-N-[4-phenoxyphenyl]-benzamide) has oppos

14 Complete data were available for 1064 ICAs and 3348 CCAs.

15 Compound 21 (ICA-17043) was advanced into phase 3 clinical trials for

16 In acute ICA occlusion, the absence of AChA infarction or restric

17 hors studied consecutive patients with acute ICA occlusion admitted to an academic medical centre bet

18 After ICA processing, the event-related response was detected

19 All ICAs lack one (or more) of the amino acid ligands in eac

20 We found empirical evidence of alternative ICA-based metrics of connectivity when comparing subject

21 Although ICA greatly attenuates ERG inactivation by shifting its

22 an initially negative study demonstrated an ICA on follow-up, despite the high frequency of risk fac

23 Then, isotope cluster analysis (ICA) was applied to the LC-ToF-MS data allowing specific

24 ims that two independent component analysis (ICA) algorithms, Infomax and FastICA, which are widely u

25 iltering and independent component analysis (ICA) and require no prior assumptions about the spatial

26 e selection, independent component analysis (ICA) and SE to create orthogonal representations that de

27 onents using independent component analysis (ICA) and seed-based correlations.

28 is following independent component analysis (ICA) and voxel-level, brain-wide univariate correlation

29 d by spatial independent component analysis (ICA) and working-memory-load-dependent connectivity betw

30 Independent component analysis (ICA) further identified between-group differences in eng

31 nalysis used independent component analysis (ICA) in 324 healthy controls, 296 SZ probands, 300 PBP p

32 ielded by an independent component analysis (ICA) of EEG data and measured event-related responses by

33 Local independent component analysis (ICA) revealed that this activity contained three distinc

34 We used independent component analysis (ICA) to analyze the component mechanisms contributing to

35 on (SVD) and Independent Component Analysis (ICA) to gene expression traits derived from a cross betw

36 s the use of Independent Component Analysis (ICA) to identify variation likely caused by broad impact

37 we used the independent component analysis (ICA) to reduce "global interference" (heartbeat and cont

38 onnectivity, independent component analysis (ICA) to reveal functional networks with a data-driven ap

39 We applied independent component analysis (ICA) to task-free fMRI data within a local region around

40 Independent component analysis (ICA) was applied to 20 variables indexing obesity and BP

41 Independent component analysis (ICA) was performed to derive resting-state functional MR

42 In addition, independent component analysis (ICA) was used to assess group differences in the express

43 Group independent component analysis (ICA) was used to decompose fMRI scans into 75 brain netw

44 Independent component analysis (ICA), a modern statistical method, allows us to better u

45 with spatial independent component analysis (ICA), called ME-ICA, which distinguishes BOLD (neuronal)

46 multi-scale independent component analysis (ICA), to first infer regulatory signals and then identif

47 Independent component analysis (ICA)-based mapping has shown advantage, as no a priori i

48 clination of independent component analysis (ICA).

49 followed by Independent Components Analysis (ICA) and by classical methods such as free radical scave

50 gies, including KCa3.1 blockers (TRAM-34 and ICA-17043) or KCa3.1-specific small hairpin RNA delivere

51 compared with SR coronary CT angiography and ICA (83% vs 53%, P < .001).

52 ovided with both coronary CT angiography and ICA has poor discriminatory power for ischemia-inducing

53 al networks with a data-driven approach, and ICA-based interhemispheric correlation analysis.

54 separate day, however, exercise capacity and ICA, MCA Vmean and CCA dynamics were preserved.

55 sitybicyclo[2.2.1]heptane-2-carboxamide) and ICA-069673 N-(6-chloropyridin-3-yl)-3,4-difluorobenzamid

56 otal of 230 subjects underwent both CCTA and ICA (59.1% male; mean age: 57 +/- 10 years).

57 obstructive CAD (>50% stenosis) on CCTA and ICA.

58 ned by a stenosis of 50% or larger on CT and ICA.

59 ent both quantitative H(2)(15)O PET/CTCA and ICA.

60 Based on these results, ML213 and ICA-069673 likely bind to different sites and are differ

61 We compared the effects of ML213 and ICA-069673 on homomeric human Kv7.4, Kv7.5, and heterome

62 binding of monoclonal antibodies PAb421 and ICA-9; two antibodies whose contiguous epitopes overlap

63 Folin-Ciocalteu, ORAC, DPPH, ABTS, PFRAP and ICA), inhibitory property against beta-amyloid and alpha

64 higher incidence of intracranial aneurysms (ICA) than the general population.

65 of follow-up invasive coronary angiography (ICA) and revascularization (REV) after coronary computed

66 (MBIR) using invasive coronary angiography (ICA) as a standard of reference.

67 (AF) by using invasive coronary angiography (ICA) as the reference method and to compare the results

68 referred to immediate coronary angiography (ICA) irrespective of their first postresuscitation ECG a

69 Invasive coronary angiography (ICA) with measurement of fractional flow reserve (FFR) b

70 underwent CT, invasive coronary angiography (ICA), FFR, and FFR(CT) between October 2010 and October

71 UC underwent invasive coronary angiography (ICA), whereas 4.6% of patients undergoing CCTA versus 2.

72 PET/CTCA and invasive coronary angiography (ICA).

73 stenosis) on invasive coronary angiography (ICA).

74 ts undergoing invasive coronary angiography (ICA).

75 y referral to invasive coronary angiography (ICA).

76 comparison to invasive coronary angiography (ICA).

77 referred for invasive coronary angiography (ICA).

78 lso underwent invasive coronary angiography (ICA).

79 Isolated congenital anosmia (ICA) is a rare condition that is associated with life-lo

80 antibodies, including islet cell antibodies (ICAs), reflect adaptive immunity, while increased serum

81 Applying ICA to a model problem, construction of custom transcrip

82 min(-1) through an internal carotid artery (ICA) - the major vascular supply of the forebrain.

83 s (CCAs) and in one internal carotid artery (ICA) 2 mm above the flow divider.

84 was measured at the internal carotid artery (ICA) and vertebral artery (VA) and CBF velocity at the m

85 n (REP) through the internal carotid artery (ICA) following small clot embolization.

86 nificant linkage to internal carotid artery (ICA) IMT (two-point log odds [LOD] score 4.1, multipoint

87 id artery (CCA) and internal carotid artery (ICA) IMT and IMT progression.

88 avernous segment of internal carotid artery (ICA) is a relatively rare entity.

89 guish true cervical internal carotid artery (ICA) occlusion from pseudo-occlusion (defined as an isol

90 s) and extracranial internal carotid artery (ICA) stenosis as risk factors for silent cerebral infarc

91 cervical segment of internal carotid artery (ICA) together with a dissecting aneurysm in the cavernou

92 rotid artery (CCA), internal carotid artery (ICA), and bulb segments of the carotid arteries were mea

93 bral blood vessels [internal carotid artery (ICA), basilar artery (BA), middle cerebral artery (MCA)]

94 s injected into the internal carotid artery (ICA).

95 of the intracranial internal carotid artery (ICA; 26 patients: median National Institutes of Health S

96 rtery (CCA) and the internal carotid artery (ICAs) and with incident or progressive plaque in the ICA

97 occlusion (terminal internal carotid artery [ICA] with M1 middle cerebral artery and/or A1 anterior c

98 Isolated congenital asplenia (ICA) is characterized by the absence of a spleen at birt

99 he etiology of isolated congenital asplenia (ICA), a life-threatening human condition, are unknown.

100 novel flow cytometry-based Ig capture assay (ICA) for the identification and sorting of individual Ab

101 tenuated in vivo by infectious center assay (ICA).

102 veloped a novel immunochromatographic assay (ICA) with enhanced sensitivity for the visual and quanti

103 ch we refer to as iterative capped assembly (ICA), that adds DNA repeat monomers individually to a gr

104 A >/=50% stenosis at ICA or a fractional flow reserve </= 0.80 was considered

105 (IAA), and islet cytoplasmic autoantibodies (ICA)].

106 removing hERG channel inactivation, because ICA-105574 (2 microM) shifts the midpoint of the voltage

107 chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243) as a selective activator of the neuronal M cu

108 ry of 3-nitro-N-(4-phenoxyphenyl) benzamide (ICA-105574), a potent and efficacious hERG channel activ

109 3-Nitro-n-(4-phenoxyphenyl) benzamide [ICA-105574 (ICA)] has been discovered to activate hERG1

110 the first direct comparison of RSNs between ICAs and graph-based network analyses at a comparable re

111 MnPO-PVN neurones (n = 16) responded to both ICA injection of hypertonic NaCl and Ang II.

112 37 (54.4%) had an abnormal FFR determined by ICA.

113 able to the corresponding RSNs identified by ICA.

114 hERG1 channel (G628C/S631C) was inhibited by ICA and that the addition of the F557L mutation rendered

115 ) nitrate and imidazolate-2-carboxyaldehyde (ICA) and found to have the sodalite-type topology.

116 lex ultrasonography at the internal carotid (ICA) and vertebral arteries (VA).

117 In each case, ICA-069673 induced a negative shift of the activation cu

118 In SH-SY5Y human neuroblastoma cells, ICA-27243 produced membrane potential hyperpolarization

119 Results Cervical ICA pseudo-occlusion occurred in 12 of 37 patients (32.4

120 strate a lack of attenuation in the cervical ICA on the symptomatic side (24 men and 13 women; mean a

121 (32.4%) with nonattenuation of the cervical ICA on the symptomatic side.

122 es to assess whether there was true cervical ICA occlusion.

123 -clamp studies of recombinant hERG channels, ICA-105574 steeply potentiated current amplitudes more t

124 In conclusion, ICA-27243 represents the first member of a novel chemica

125 In contrast, ICA-121431, a small-molecule Nav1.1 inhibitor, accelerat

126 In contrast, ICA-27243 was less effective at activating KCNQ4 and KCN

127 t allele in exon 1 of SCARB1, with decreased ICA IMT compared with subjects homozygous for the common

128 ) without known CAD who underwent diagnostic ICA within 6 mo of HS-SPECT and 86 consecutive patients

129 25% of patients with ADPKD with a documented ICA demonstrated a new ICA on follow-up.

130 missense mutations-cause autosomal dominant ICA by haploinsufficiency.

131 For patients with <50% stenosis, early ICA rates were elevated; over the entirety of follow-up,

132 Although the gene encoding ICA in humans is classified as a pseudogene, an apparent

133 ble logistic regression was used to estimate ICA use.

134 For ICA pseudoaneurysms treated with aspirin and observation

135 ive hazard for death was 2.2 (p = 0.011) for ICA versus no ICA.

136 , the relative hazard for death was 0.61 for ICA versus no ICA (p = 0.047).

137 ing to the postresuscitation ECG blinded for ICA results: (1) ST elevation or presumably new left bun

138 in detecting patients with an indication for ICA after experiencing a cardiac arrest.

139 ds that form the putative binding pocket for ICA in ERG are conserved in EAG.

140 isk for CAD (n = 184) who were scheduled for ICA were randomly assigned for study with SR (n = 91) or

141 This association was less significant for ICA IMT (beta +/- SE: -0.049 +/- 0.023, P = 0.05) and no

142 +/- 0.023, P = 0.05) and not significant for ICA IMT progression (beta +/- SE: -0.013 +/- 0.014, P =

143 ed as a pseudogene, an apparently functional ICA gene has been annotated in mice, rats, cows, pigs, a

144 For the testing group, ICA and seed-based correlation were separately computed

145 The results show that our knowledge-guided ICA approach can extract biologically meaningful regulat

146 Elevated levels of CML in ICA(+) children were a persistent, independent predictor

147 nd ERG channels is related to differences in ICA binding site or to intrinsic mechanisms of inactivat

148 The absolute increase in ICA after CCTA was 21 per 1,000 CCTA patients (95% CI: 1

149 CML was increased in ICA(+) and prediabetic schoolchildren and in diabetic an

150 In all conditions, reductions in ICA and MCA Vmean were associated with declining cerebra

151 sed ED cost and length of stay but increased ICA and revascularization.

152 We assessed internal (ICA) and common carotid artery (CCA) haemodynamics (indi

153 nt) or tandem (extracranial or intracranial) ICA and M1 occlusion subgroup also showed a trend favori

154 xt of acute ischemic stroke with ipsilateral ICA nonattenuation at single-phase CT angiography, even

155 y (269 +/- 11 vs. 336 +/- 14 W), and lowered ICA and MCA Vmean by 12-23% without compromising CCA blo

156 Seed-based analysis showed that many ICA components exhibited strong and significant (P < .05

157 dian 16 mum/year; P < 0.001) and the maximal ICA-IMT increased in 70% (median 25 mum/year; P < 0.001)

158 For the maximal ICA-IMT, cumulative prednisone exposure was associated w

159 ependent component analysis (ICA), called ME-ICA, which distinguishes BOLD (neuronal) and non-BOLD (a

160 In contrast to ML213, ICA-069673 robustly activated Kv7.4 channels but was sig

161 Most ICA procedures (79%) occurred </=3 months of CCTA.

162 ns abolished the activator effects of 30 muM ICA, including L622C in the pore helix, F557L in the S5

163 ted guinea pig ventricular cardiac myocytes, ICA-105574 induced a concentration-dependent shortening

164 PKD with a documented ICA demonstrated a new ICA on follow-up.

165 hazard for death was 0.61 for ICA versus no ICA (p = 0.047).

166 death was 2.2 (p = 0.011) for ICA versus no ICA.

167 of proximal intracranial arterial occlusion (ICA vs MCA-M1 vs MCA-M2) was not.

168 ation in S6 (A653M) switched the activity of ICA from an activator to an inhibitor, revealing its par

169 s on inactivation, greater concentrations of ICA-105574 (3 microM) produced comparatively small hyper

170 (n = 621), there was a strong correlation of ICA with CCTA findings (OR: 9.09, 95% CI: 5.57 to 14.8,

171 of more than 50% compared with detection of ICA were 96.4% and 98.7%, respectively, in the chronic A

172 G1 to identify the molecular determinants of ICA action.

173 Simulated molecular docking of ICA to homology models of hERG1 corroborated the scannin

174 potently blocked the stimulatory effects of ICA-105574.

175 e decorated by the aldehyde functionality of ICA which has allowed its transformation to the alcohol

176 is useful to select patients with no need of ICA.

177 for role of CNGA2 gene with pathogenicity of ICA in humans.

178 ver the entirety of follow-up, predictors of ICA were mild left main, mild proximal CAD, respectively

179 ctivation rates decreased in the presence of ICA-069673 in a subunit-specific manner.

180 tive CAD was associated with higher rates of ICA and REV for 1-vessel (44.3% and 28.0%), 2-vessel (53

181 The odds ratio of ICA for CCTA patients versus UC patients was 1.36 (95% c

182 This study show that reperfusion of ICA can increase RCBF following embolization, but this i

183 ced in the narrowed and dissected segment of ICA, and the dissecting aneurysm of the cavernous segmen

184 ce of coronary CT angiography versus that of ICA in each group.

185 icant CAD when FFR determined at the time of ICA was the reference standard.

186 uminal narrowing) was assessed on CTA and on ICA.

187 In patients with CAD on ICA, the magnitude of reversible defects was greater wit

188 Para-ICA identified five sub-DMNs that were significantly ass

189 Para-ICA identified four ERP components that were significant

190 arallel independent component analysis (para-ICA) to determine which empirically derived gene cluster

191 ) then was subjected to a parallel ICA (para-ICA) to identify imaging-genetic relationships.

192 1-million-SNP array) was examined using para-ICA.

193 s (n = 549) then was subjected to a parallel ICA (para-ICA) to identify imaging-genetic relationships

194 ICA methods, including a single-participant ICA on the basis of a comprehensive template from core s

195 ed by limited trypsin proteolysis of porcine ICA.

196 coronary artery disease (CAD); accurate pre-ICA risk stratification is needed.

197 were determined by radioimmunoprecipitation, ICA was determined by indirect immunofluorescence, and H

198 n, smoking, and a family history of ruptured ICA.

199 method, namely knowledge-guided multi-scale ICA, to identify disease-specific biomarkers.

200 zation of a large Iranian family segregating ICA.

201 Similarly, ICA revealed worse rs-fMRI expression scores across all

202 Since ICA builds full-length constructs from individual monome

203 tly identified across subjects using spatial ICA (independent component analysis).

204 occlusions; carotid T- or L-type and tandem ICA and M1 occlusions showed greater recanalization and

205 Together, our findings indicate that ICA is a mixed agonist of hERG1 channels.

206 We show that ICA generated patterns that clearly characterized the ma

207 Together these findings suggest that ICA binds to the same site in EAG and ERG channels to el

208 with site-directed mutagenesis suggests that ICA binds in a channel-specific orientation to a hydroph

209 The ICA anticodon in the A34 mutant tRNA decoded Cys codons,

210 The ICA provides important added benefits in that phenotypic

211 The ICA represents a fast and versatile tool for single-cell

212 e CA slopes ranging from 0.37 to 2.20 at the ICA and from 0.17 to 3.18 at the VA; no differences in C

213 no differences in CA were found between the ICA and VA.

214 nt (P < .05) correlations, corroborating the ICA results.

215 We envisage the ICA as being a useful tool in Ab repertoire analysis for

216 Except for the ICA assay, a good correlation between phenolic content a

217 Optical signals were restored from the ICA components with artifactual components removed and t

218 Atherosclerotic thickening in the ICA appears to be accommodated for vessels with a maximu

219 In the ICA, lumen area was relatively constant across patients

220 d with incident or progressive plaque in the ICA/carotid bulb, were explored.

221 gion around the bilateral TPJ, iterating the ICA at multiple model orders and in several datasets.

222 Complete sympathetic reinnervation of the ICA was observed at long term survival times, yet TH inn

223 To show the specificity of the ICA, we produced Ag-specific Abs from these cells and su

224 h-type immunoreactions were performed on the ICA, and Pt-Au bimetal nanoparticles (NPs) were accumula

225 tations introduced into EAG to replicate the ICA binding site in ERG did not alter the functional res

226 all short of proving this claim and that the ICA algorithms are indeed doing what they are designed t

227 wave instruments can be improved through the ICA method capable to remove noise, global interference

228 Furthermore, we used the ICA to track Ag-specific plasmablast responses in HIV-va

229 ified visually (for heartbeat) and using the ICA weight matrix (for superficial layers).

230 The ICAs were evaluated for coronary stenosis based on quant

231 These ICA also rupture at an earlier age in patients with ADPK

232 s a valid noninvasive imaging alternative to ICA in selected patients at low to intermediate risk of

233 A as an effective noninvasive alternative to ICA to rule out obstructive coronary artery stenosis.

234 A may be used effectively as a gatekeeper to ICA.

235 Kv7.4 W242L responded to ICA-069673-like wild-type Kv7.4, but a Kv7.4 F143A mutan

236 e whether the inverse functional response to ICA in EAG and ERG channels is related to differences in

237 nt increase in cell discharge in response to ICA injection of Ang II but not hypertonic NaCl.

238 d no change in cell discharge in response to ICA injection of hypertonic NaCl or Ang II.

239 ERG did not alter the functional response to ICA.

240 urones that expressed Fos-ir in responses to ICA hypertonic NaCl infusions was greater in the DC (P <

241 channels displayed intermediate responses to ICA-069673.

242 v7.4 F143A mutant was much less sensitive to ICA-069673.

243 Computed tomography, ICA, FFR, and FFR(CT) were interpreted in blinded fashio

244 Traumatic ICA pseudoaneurysms are safely treated with daily aspiri

245 We retrospectively identified all traumatic ICA pseudoaneurysms diagnosed on head/neck computed tomo

246 natural history and management of traumatic ICA pseudoaneurysms is controversial.

247 2; range, 55-83 years]) scheduled to undergo ICA for suspected ISR were enrolled.

248 ass index range 17 to 39 kg/m(2)) undergoing ICA for CAD evaluation, a CTA was acquired using very lo

249 Among patients undergoing ICA (n = 621), there was a strong correlation of ICA wit

250 est that only a third of patients undergoing ICA have obstructive coronary artery disease (CAD); accu

251 t without a clear noncardiac cause underwent ICA.

252 Eighty-six patients underwent ICA, and 39 had low-likelihood of CAD.

253 They underwent ICA and coronary CT angiography performed with a whole-h

254 oronary CT angiography before they underwent ICA.

255 In 86 patients who underwent ICA, sensitivity of PET was higher than SPECT (78.8% vs.

256 Post-CCTA patterns of follow-up ICA and REV are incompletely defined.

257 During follow-up, ICA rates for patients with no CAD to mild CAD according

258 We used ICA to synthesize 20 TALENs of varying DNA target site l

259 rmed at 3 T to characterize the DMN by using ICA methods, including a single-participant ICA on the b

260 After parcellating the cortex using ICA and segmenting the thalamus based on dominant connec

261 nguage network in brain tumor subjects using ICA on rs-fMRI.

262 ion scores within the planum temporale using ICA.

263 eral extracranial internal carotid artery (V(ICA)) was calculated.

264 ICA) were 30-196 and 36-175; and those for V(ICA) were 18-116 and 15-95, respectively.

265 y (US), and carotid US to determine V(MCA)/V(ICA) and V(tICA)/V(ICA) ratios from angle-corrected and

266 e stepwise approach with use of the V(MCA)/V(ICA) ratio after flow velocity measurements in the MCA r

267 Accuracy of the V(MCA)/V(ICA) ratio calculated on the basis of end-diastolic velo

268 se of MCA velocity measurements and V(MCA)/V(ICA) ratio can increase the accuracy of Doppler US.

269 and 108 cm/sec and a peak systolic V(MCA)/V(ICA) ratio of 3.6 and 3.9 for diagnosis of mild and mode

270 nce ranges for mean angle-corrected V(MCA)/V(ICA) ratio on the left and right sides were 1.2-4.0 and

271 e dependent, contrary to V(ICA) and V(MCA)/V(ICA) ratio, after controlling for hematocrit and hemoglo

272 ers were peak systolic velocity and V(MCA)/V(ICA) ratio.

273 ides reference limits for V(MCA), V(tICA), V(ICA), and velocity ratios obtained from children with SC

274 V(MCA), V(tICA), and V(tICA)/V(ICA) ratio were not age dependent, contrary to V(ICA) an

275 US to determine V(MCA)/V(ICA) and V(tICA)/V(ICA) ratios from angle-corrected and uncorrected velocit

276 ratio were not age dependent, contrary to V(ICA) and V(MCA)/V(ICA) ratio, after controlling for hema

277 vB-ICA-mm placed 68.6% of the eyes with GON in a cluster la

278 vB-ICA-mm represented the SAP fields with patterns that wer

279 pendent component analysis mixture model (vB-ICA-mm) partitioned the SAP fields into the most informa

280 Thirty-two of 191 eyes progressed on vB-ICA-mm by this definition.

281 The vB-ICA-mm can quantitatively identify progression in eyes w

282 The vB-ICA-mm identified a higher percentage of progressing eye

283 .42 visual fields were evaluated with the vB-ICA-mm.

284 er study, it was shown that a model using vB-ICA-mm can separate normal fields from fields with six d

285 These findings should validate vB-ICA-mm as a data-mining technique for new and unfamiliar

286 y involved extracranial stenosis segment was ICA, present in 14 (66.6%) out of 21 extracranial segmen

287 unselected schoolchildren screened, 115 were ICA(+) and were tested for baseline CML and diabetes aut

288 The primary mechanism by which ICA-105574 potentiates hERG channel activity is by remov

289 The reason why ICA family members have lost the ability to bind iron is

290 10 (38.5%), 20 (38.5%), and 26 (54.2%) with ICA, MCA-M1, and MCA-M2 occlusions, respectively, achiev

291 T angiography showed a better agreement with ICA for calcified plaques compared with SR coronary CT a

292 y and were compared with those attained with ICA.

293 The strong association of CCTA with ICA suggests that it may serve as an effective "gatekeep

294 with high diagnostic accuracy compared with ICA ( 3 , 4 ).

295 tion with the two scanners was compared with ICA and intravascular US.

296 tecting coronary stenosis when compared with ICA.

297 exome sequencing of a multiplex kindred with ICA, we identify a heterozygous missense mutation (P236H

298 34), and 40.9% (9 of 22) among patients with ICA, MCA-M1, and MCA-M2 occlusions, respectively.

299 In this first comparison of HS-SPECT with ICA, new automated quantification of combined upright an

300 ysis was performed for cross validation with ICA networks by using Pearson correlation.