ライフサイエンスコーパス: ICM

1 ICM and TP transformations were simulated as a cometabol

2 ICM is now recognized as a primary specialty in Spain, S

3 ICM patients had 27 appropriate ICD events, and NICM pat

4 ICM patients remain a clinical conundrum.

5 ICM pretreatment of aged rats with Box-A 24 h before E.

6 ICM pretreatment with Box-A also inhibited aging-induced

7 ICM Web is suitable for interactively investigating nucl

8 ICMs isolated from more advanced blastocysts no longer r

9 Among these, only 2 (ICM) and 5 (NICM) miRNAs are normalized with LVAD.

10 During 46.7 patient-years, 6 (2.2%) ICM patients received an appropriate shock; 5 survived t

11 d systolic and diastolic function in 1 in 20 ICM and 1 in 5 NICM patients.

12 ial ablation could abolish all Epi-LAVA in 4 ICM and 2 ARVC patients, whereas all patients with NICM

13 Among the 679 (ICM) and 570 (NICM) lncRNAs differentially expressed wit

14 Two (0.7%) ICM patients received an inappropriate shock.

15 A total of 74 ICM and 34 NICM were followed for 63 months (1-140) and

16 nate Epi-LAVA at least partially in 15 (83%) ICM, 2 (13%) NICM, and 11 (73%) ARVC patients, contribut

17 thways, however, much more severely affected ICM development (7-8 cells).

18 sion of FGFR2, it is FGFR1, expressed by all ICM cells, that is critical for establishment of a PrE i

19 ion, we noted no effect or conversion of all ICM cells to GATA6-positive PrE.

20 Among ICM patients with AF detected, the median time to AF det

21 l LV endocardial pacing locations vary among ICM patients remain unknown.

22 M both at ICE and TEE, 1 patient (2%) had an ICM at ICE and a negative TEE, and 53 patients (95%) had

23 n of Mek1/2 in ES cells helps to maintain an ICM-like epigenetic state, prolonged suppression results

24 ECG monitoring with an ICM was superior to conventional follow-up for detecting

25 We show that morula compaction and ICM formation depend on PC7 and the related proprotein c

26 Among patients with DCM and ICM, the risk of cardiovascular mortality for DCM +MWHE

27 with TCM compared with patients with DCM and ICM.

28 ected from demethylation in the germline and ICM.

29 METHODS AND ICM and NICM patients who underwent LGE cardiac magnetic

30 Both DCM +MWHE and ICM were predictors of pump failure death as well as sud

31 Scintiscans of ICM-naive and ICM-administered patients were compared.

32 iate WCD therapy in newly diagnosed NICM and ICM patients according to cardiomyopathy etiology in an

33 success rates after VT ablation in NIDCM and ICM patients were similar, the long-term outcomes in NID

34 meres and prevents segregation of the TE and ICM lineages and blastocyst formation.

35 e show that proper development of the TE and ICM lineages is coordinated via combinatorial regulation

36 Proper development of the TE and ICM lineages is dependent upon establishment of specific

37 lastocyst and their allocation to the TE and ICM, suggesting that TE-ICM bias arises separately from

38 a major role in the specification of TE and ICM.

39 s capable of contributing to both the TE and ICM.

40 functionally contribute to establish TE- and ICM-specific transcriptional programs are poorly underst

41 ribution of 173 proteins between the UPB and ICM fractions.

42 ecursor-product relationship between UPB and ICM.

43 .4+/-14.2 years, NICM 49.8+/-12.4 years, and ICM 57.5+/-8.0 years; P<0.001) and more frequently liste

44 While the status of XCI in human embryos and ICMs remains unknown, majority of human female ESCs show

45 A at the facing site, 48 (28%) applications (ICM: 20 of 71 [28%], NICM: 3 of 39 [8%], ARVC: 25 of 63

46 concentration to evaluate the delay between ICM administration and radioiodine therapy in patients w

47 able ventricular tachycardia differs between ICM and NICM.

48 e nor NIS protein expression was affected by ICM.

49 sing cells was not significantly affected by ICM.

50 Three-year monitoring by ICM in cryptogenic stroke patients demonstrated a signif

51 cumented chronic and dilated cardiomyopathy (ICM, n = 61; NICM, n = 93) requiring durable support wit

52 pathy (DCM) and inflammatory cardiomyopathy (ICM).

53 omyopathy (NICM) or ischemic cardiomyopathy (ICM) against sudden cardiac death while awaiting re-eval

54 or (ICD) therapy in ischemic cardiomyopathy (ICM) and nonischemic cardiomyopathy (NICM) patients and

55 ure events, both in ischemic cardiomyopathy (ICM) and nonischemic dilated cardiomyopathy (DCM).

56 , its role in human ischemic cardiomyopathy (ICM) has never been analysed.

57 , but the impact of ischemic cardiomyopathy (ICM) has not been specifically investigated.

58 nt of patients with ischemic cardiomyopathy (ICM) have questioned both the added value of revasculari

59 the pathogenesis of ischemic cardiomyopathy (ICM) in animal models, substantial questions remain unan

60 ll (MSC) therapy in ischemic cardiomyopathy (ICM) is controversial.

61 s 161 patients with ischemic cardiomyopathy (ICM) undergoing CRT (n = 258) were followed up for a max

62 myopathy (NICM) and ischemic cardiomyopathy (ICM), myocarditis patients were younger (myocarditis 43.

63 NIDCM compared with ischemic cardiomyopathy (ICM).

64 on as a therapy for ischemic cardiomyopathy (ICM).

65 T) in patients with ischemic cardiomyopathy (ICM).

66 red with those with ischemic cardiomyopathy (ICM).

67 tion heart failure (ischemic cardiomyopathy [ICM]).

68 ty-six patients (18 ischemic cardiomyopathy [ICM], 13 nonischemic dilated cardiomyopathy [NICM], 15 a

69 ed as a means for deiodination of the common ICM diatrizoate.

70 After 11 days, ICM vesicles (chromatophores) and membrane invagination

71 We revealed that TE-deprived ICMs derived from 32-cell blastocysts are still able to

72 OG, GATA6, and the FGF/ERK pathway determine ICM cell fate.

73 analyzed X-chromosome activity in developing ICMs and show that reactivation of gene expression from

74 of appropriate therapies in newly diagnosed ICM was comparable to that observed in prior observation

75 d NICM and 271 patients with newly diagnosed ICM.

76 RNAs, but not miRNAs or mRNAs, distinguishes ICM from NICM.

77 point in the gene regulatory network driving ICM lineage specification.

78 at inhibition of RHO-ROCK signaling enhances ICM and suppresses TE characteristics through activation

79 ed pharmaceuticals and metabolites excluding ICM the elimination by ozonation, PAC, and UV at the sam

80 rganizations to create core competencies for ICM using consensus methodologies to establish common gr

81 ents (11%) had ICE and TEE both positive for ICM, 8 patients (15%) had a negative TEE but a positive

82 to 87.3; p = 0.0002) was similar to that for ICM (adjusted HR: 21.0; 95% CI: 5.06 to 87.2; p < 0.0001

83 deed, prospective sorting of such cells from ICM outgrowths increased the rate of ESC derivation more

84 In group 3, 2 patients (3%) had ICM both at ICE and TEE, 1 patient (2%) had an ICM at IC

85 quantitative real-time PCR and IHC in human ICM and a rat model of coronary obstruction to demonstra

86 6 isoform in failing cardiomyocytes in human ICM in vivo.

87 he role of CD56 in the pathogenesis of human ICM.

88 ses (ICM) in all 44 patients; TEE identified ICM in 32 patients (73%).

89 In ICM patients with primary prophylactic ICD, LGE border z

90 ival in NIDCM was 40.5% compared with 57% in ICM.

91 remodeling was observed in DCM -MWHE and in ICM but not in DCM +MWHE.

92 DNA-encoded genes in DCM versus no change in ICM.

93 sis to quantify free-iodide contamination in ICM.

94 nsport and ATP synthesis are all enriched in ICM, consistent with the spatial proximity of energy cap

95 e area, vLP were observed more frequently in ICM than in NICM in endocardium (4.1% vs. 1.3%; p = 0.00

96 d its relationship with systolic function in ICM.

97 is thought to be mediated by free iodide in ICM formulations, but this hypothesis has never been for

98 of multiple scar quantification measures in ICM and DCM patients being referred for ICD.

99 0 and 147 differentially expressed miRNAs in ICM and NICM, respectively, compared with nonfailing LV.

100 le (NCAM1)] is specifically overexpressed in ICM; it was the aim of the current study to further eluc

101 Appropriate ICD therapy can be predicted in ICM patients with primary prevention ICD by quantifying

102 Although free iodide was present in ICM formulations, in vitro uptake of iodide by NIS-expre

103 Pedagogic research in ICM could usefully focus on the interplay between educat

104 rk and its interaction with Erk signaling in ICM cells.

105 MSC therapy with TESI in ICM patients improves 6MWD and MLHFQ score and reduces m

106 s in structures and processes of training in ICM across Europe, although there has been agreement on

107 der develops, which is fully incommensurate (ICM) in all three crystallographic directions.

108 We note that individual ICM cells can contribute to all three lineages of the bl

109 paired nonischemic (NICM; n=8) and ischemic (ICM; n=8) human failing LV samples collected before and

110 om nonfailing hearts and end-stage ischemic (ICM) or dilated (DCM) cardiomyopathic hearts.

111 key embryonic stem cells (ESCs) and isolated ICMs fail to incorporate into host embryos and develop i

112 osine (5-MeC) immunofluorescence in isolated ICMs, was minimally affected by inhibition of either pat

113 In addition to its ICM activity, IcmF also catalyzes the interconversion of

114 s still attached to the CM, a eukaryote-like ICM budding process was revealed, which results in the f

115 'Free-living' ICM vesicles, which possess all the machinery for conver

116 HMGB1 signaling with an intracisterna magna (ICM) injection of the competitive antagonist to HMGB1, B

117 site housing with Intensive Case Management (ICM) may be an appropriate and less-costly option for ho

118 ent states representing the inner cell mass (ICM) and epiblast embryos.

119 he pluripotent cells of the inner cell mass (ICM) and epiblast of the peri-implantation mouse embryo,

120 generate both the embryonic inner cell mass (ICM) and the supportive trophectoderm (TE).

121 Communication between the inner cell mass (ICM) and the trophoblast layer of the blastocyst is know

122 lastocyst consisting of the inner cell mass (ICM) and trophectoderm (TE).

123 erential expression between inner cell mass (ICM) and trophectoderm (TE).

124 ment, the generation of the inner cell mass (ICM) and trophoblast lineages comprises upregulation of

125 Pluripotent cells in the inner cell mass (ICM) are the descendants of totipotent cells and can dif

126 bryogenesis, cells from the inner cell mass (ICM) can be specified in epiblast (Epi) or primitive end

127 This analysis revealed that inner cell mass (ICM) cells have unrestricted developmental potential.

128 o distinguishes pluripotent inner cell mass (ICM) from differentiating trophectoderm (TE).

129 dpf), and restricted to the inner cell mass (ICM) in 128-256 cell blastocysts (6dpf), approximately 2

130 trophectoderm (TE) from the inner cell mass (ICM) in the mouse blastocyst is determined by position-d

131 toderm (TE) and pluripotent inner cell mass (ICM) is one of the earliest events during mammalian embr

132 e able to contribute to the inner cell mass (ICM) just as diploid ESCs tagged with GFP.

133 trophectoderm (TE) and the inner cell mass (ICM) lineages during preimplantation development.

134 the trophectoderm (TE) and inner cell mass (ICM) lineages in the mouse blastocyst correlates with ce

135 rom both human PSCs and the inner cell mass (ICM) of human blastocysts.

136 However, the inner cell mass (ICM) of mouse preimplantation blastocysts and their in v

137 subset of cells within the inner cell mass (ICM) of the blastocyst does not respond to differentiati

138 tain pluripotency to become inner cell mass (ICM) of the blastocyst.

139 ursors are specified in the inner cell mass (ICM) of the early blastocyst in a 'salt and pepper' mann

140 Cells of the inner cell mass (ICM) of the mouse blastocyst differentiate into the plur

141 m (PrE) lineages within the inner cell mass (ICM) of the mouse blastocyst involves initial co-express

142 is first established in the inner cell mass (ICM) of the mouse blastocyst.

143 t epiblast (EPI) within the inner cell mass (ICM) of the mouse blastocyst.

144 ineage specification in the inner cell mass (ICM) of the mouse blastocyst.

145 S) cells that resembles the inner cell mass (ICM) of the pre-implantation embryo.

146 trophectoderm (TE) and the inner cell mass (ICM), and for repressing primitive endoderm (PE) develop

147 tivation (XCI) in the mouse inner cell mass (ICM), and reactivation of X-linked genes is thought to f

148 ither trophectoderm (TE) or inner cell mass (ICM), followed by epiblast (EPI) or primitive endoderm (

149 mouse embryo generates the inner cell mass (ICM), which gives rise to the pluripotent epiblast and t

150 Here we show that inner cell mass (ICM)-generated cells expressing Blimp1, a key transcript

151 table human preimplantation inner cell mass (ICM)-like naive states with only WNT, MEK/ERK, and tanky

152 toderm cells from an apolar inner cell mass (ICM).

153 and segregating TE from the inner cell mass (ICM).

154 shares features with human inner cell mass (ICM).

155 group 1, ICE identified intracardiac masses (ICM) in all 44 patients; TEE identified ICM in 32 patien

156 omic analyses of precursor (UPB) and mature (ICM) fractions.

157 biogenesis of ICM in this bacterium mature (ICM) and precursor (upper pigmented band - UPB) membrane

158 Here, mean ICM cell numbers decreased from 18-19 in controls to 11-

159 fect of the use of iodinated contrast media (ICM) administered intravenously.

160 e detection of six iodinated contrast media (ICM) and their phototransformation products (TPs) in sur

161 Iodinated contrast media (ICM) are commonly administered pharmaceutical agents.

162 r treatment, iodinated X-ray contrast media (ICM) have been detected in municipal wastewater effluent

163 ation of the iodinated X-ray contrast media (ICM) iopamidol, iopromide, iohexol, iomeprol, and diatri

164 ments consisted of iodinated contrast media (ICM).

165 In intensive care medicine (ICM), the differences in national training programs were

166 ions of the iodinated X-ray contrast medium (ICM) iomeprol were studied at the stream/groundwater int

167 kelvin), X-ray-emitting intracluster medium (ICM) is the dominant baryonic constituent of clusters of

168 c analysis of the intracytoplasmic membrane (ICM) development process was performed in Rhodobacter sp

169 ate a specialized intracytoplasmic membrane (ICM) system for the conversion of solar energy to ATP.

170 ensive system of intracytoplasmic membranes (ICM) in order to increase the surface area for absorbing

171 re absent from the intra-cloacal mesenchyme (ICM), a cell mass that divides the cloaca into dorsal hi

172 nitoring with an insertable cardiac monitor (ICM) is more effective than conventional follow-up (cont

173 monitoring via insertable cardiac monitors (ICM).

174 m both chromosomes in isolated female monkey ICMs indicating that ex vivo pluripotent cells retain Xa

175 rase (BHMT), which is expressed in the mouse ICM.

176 Mga mutant cells, and the survival of mutant ICM cells as well as ESCs is rescued in culture by the a

177 amily members include isobutyryl-CoA mutase (ICM), which interconverts isobutyryl-CoA and n-butyryl-C

178 a negative TEE, and 53 patients (95%) had no ICM at ICE and TEE.

179 tribute to a methyl pool required for normal ICM development and establishing initial embryonic DNA m

180 prisingly, Myc and E2F targets in Sin3a-null ICMs are downregulated, suggesting a central but non-can

181 he clinical VT only was achieved in 18.3% of ICM and in 22.2% of NIDCM patients.

182 s achieved in 66.7% of NIDCM and in 77.4% of ICM patients.

183 ral anticoagulation prescription in 94.7% of ICM patients with AF detected at 6 months, 96.6% at 12 m

184 Finally, the ability of ICM to perturb iodide uptake in the thyroid may be used

185 intravenous or sublingual administration of ICM led to a reduction in radiotracer uptake by the thyr

186 udy provides evidence that biodegradation of ICM occurs at the field-scale also for predominantly den

187 In order to study the biogenesis of ICM in this bacterium mature (ICM) and precursor (upper

188 (140kD) overexpression in the development of ICM using differential whole transcriptome expression an

189 ents a useful technique for the diagnosis of ICM, thus providing improved imaging of right-sided lead

190 diagnosis of DCM, and 91 had a diagnosis of ICM.

191 t to prospectively investigate the effect of ICM HF etiology on LVAD-associated improvement of cardia

192 er (NIS) were used to quantify the effect of ICM on iodide uptake.

193 and suggest a direct and selective effect of ICM on the thyroid.

194 The thyroid-selective effect of ICM was also observed in humans.

195 The elimination of ICM by the tested post-treatment technologies was 50-65%

196 tor Y-27632 exhibited elevated expression of ICM marker NANOG and reduced expression of CDX2 at the b

197 meric dysfunction are molecular hallmarks of ICM in humans, our results provide strong evidence that

198 states, did not express genes indicative of ICM-derived tissues.

199 plays a pivotal role in the pathogenesis of ICM and may be a target for future immunotherapeutic str

200 Scintiscans of ICM-naive and ICM-administered patients were compared.

201 First, a photodegradation study of ICM in surface water using a sunlight lab-scale simulato

202 A variant in which the two subunits of ICM are fused to a G-protein chaperone, IcmF, has been d

203 ion superior to OMT in improving survival of ICM patients.

204 with midwall fibrosis is similar to that of ICM.

205 in vitro culture, confirming totipotency of ICM cells at this stage.

206 approach for reducing the concentrations of ICMs in wastewater, electrochemical reduction at three-d

207 stroke were randomized to control (n=220) or ICM (n=221) and followed for </=36 months.

208 dy of 5,307 consecutive patients with DCM or ICM, no history of sustained ventricular arrhythmias, wh

209 structure reappears, along with second-order ICM Bragg peaks, which polarized neutron data demonstrat

210 All other ICM did not show significant reactivity, regardless of t

211 ds to the death of proliferating pluripotent ICM cells in vivo and in vitro, and the death of embryon

212 table acquisition of a human preimplantation ICM-like ground state via modulation of WNT signaling, a

213 states without passing through the previous ICM state, in contrast to what is observed in vivo.

214 e interactive chromatin modeling web server (ICM Web) is an interactive tool that allows users to rap

215 Gene expression profiling of 534 single ICM cells identified distinct downstream targets associa

216 ousing (using rent supplements) and off-site ICM services.

217 Some ICM vesicles have no connection with other structures, o

218 METHODS AND About 157 patients with stable ICM and no substantial impairment of kidney function rec

219 ocardial injury even in patients with stable ICM.

220 ound that after this first restriction step, ICM cells still retain fate flexibility, manifested by a

221 cation to the TE and ICM, suggesting that TE-ICM bias arises separately from embryonic-abembryonic bi

222 We demonstrated that ICM reduce thyroid uptake of iodide independently of fre

223 ultrastructural experiments have shown that ICM assembly in Rhodobacter sphaeroides is initiated at

224 owever, TEAD4 is expressed in the TE and the ICM.

225 nt to those two post-treatments, such as the ICM diatrizoate, can be substantially removed only by hi

226 In both the ICM and NIDCM subgroups, procedure failure and incomplet

227 thod that enable us to evaluate directly the ICM heating rate from the dissipation of turbulence.

228 t embryonic stem (ES) cells derived from the ICM generate and shed microvesicles (MVs), a major class

229 y clusters, radiative energy losses from the ICM occur on timescales much shorter than the age of the

230 reduced to a level equivalent to that in the ICM and is non-random, with gain of methylation at speci

231 ises upregulation of Nanog expression in the ICM and its silencing in the trophoblast.

232 Cumulative AF detection rates in the ICM arm increased progressively during this period (3.7%

233 had been detected in 8.9% of patients in the ICM group (19 patients) versus 1.4% of patients in the c

234 ad been detected in 12.4% of patients in the ICM group (29 patients) versus 2.0% of patients in the c

235 mosome inactivation (XCI) takes place in the ICM lineage after implantation or upon differentiation o

236 tion in the TE lineage and repression in the ICM lineage.

237 ecifically enriched in PrE precursors in the ICM prior to cell sorting and prior to overt signs of ce

238 In the ICM subcohort, peri-infarct signal showed only a nonsign

239 chanism to reactivate Xp-linked genes in the ICM that operates independently of loss of Xist RNA and

240 ects on cell numbers and 5-MeC levels in the ICM were completely rescued by methionine (immediate SAM

241 s initially heterogeneously expressed in the ICM where it co-localized with a sub-set of OCT4 express

242 In the ICM, loss of Klf5 resulted in reduced expression of plur

243 proteins, only 43 of which were found in the ICM, reflecting its specialized role within the cell, th

244 gether, our observations suggest that in the ICM, X-linked gene transcription and Xist coating are un

245 zation to enable proper specification of the ICM and TE lineages.

246 ool, and that the lineage composition of the ICM is conserved regardless of its size.

247 omography demonstrates the complexity of the ICM of Rba. sphaeroides.

248 epresentation, along with a splitting of the ICM peaks along the h direction which indicates that the

249 Below15 K the k component of the ICM structure reappears, along with second-order ICM Bra

250 Although the size of the ICM was unaffected in Fgf4 null mutant embryos, it entir

251 associated with the high variability of the ICM wastewater discharge into the investigated stream.

252 entation appears, and the k component of the ICM wave vector disappears.

253 Since the ICM exists only transiently in vivo, it remains unclear

254 iptional profile stabilizes earlier than the ICM and prior to blastocyst formation.

255 ion of how this energy is transferred to the ICM remains open.

256 thereby allowing their maturation toward the ICM lineage.

257 ive activities of FGFR1 and FGFR2 within the ICM coordinate establishment of two distinct lineages.

258 in a salt-and-pepper distribution within the ICM, subsequently becoming restricted to the nascent PrE

259 g and speed of lineage commitment within the ICM.

260 itive endoderm (PE) specification within the ICM.

261 e segregation of epiblast and PrE within the ICM.

262 equired for lineage establishment within the ICM.

263 Whether this applies to ICM and whether optimal LV endocardial pacing locations

264 Cs in 30 patients with LV dysfunction due to ICM between April 2, 2010, and September 14, 2011, with

265 The DNA cleavage sites were analyzed using ICM Molsoft software and three-dimensional physical mode

266 nd optimal cerebral perfusion pressure using ICM+ software (Cambridge Enterprise, University of Cambr

267 Data were collected and pre-processed using ICM+ software.

268 0.05 versus nonfailing hearts, P<0.05 versus ICM).

269 ation (myocarditis 11% versus NICM 2% versus ICM 4%; P<0.001), biventricular mechanical circulatory s

270 port (myocarditis 19% versus NICM 2%, versus ICM 2%; P<0.001), and extracoroporeal membrane oxygenati

271 s 1A (myocarditis 44% versus NICM 21% versus ICM 21%; P<0.001), with significantly higher need for me

272 tion (myocarditis 5% versus NICM 0.4% versus ICM 1%; P<0.001).

273 [95% confidence interval, 1.63-3.79] versus ICM and hazard ratio, 2.12 [95% confidence interval, 1.4

274 tion, as TE derives from outer cells whereas ICM from inner cells.

275 me of transcriptional stabilization, whereas ICM cells still retain the ability to regenerate TE up t

276 y-seven patients, 63 with NIDCM and 164 with ICM, presenting with sustained VT were ablated with radi

277 e patients referred for ICD therapy (59 with ICM and 65 with DCM) underwent a standardized LGE-CMR pr

278 and increased in number in DCM compared with ICM or nonfailing hearts.

279 d (P<0.001) in DCM hearts in comparison with ICM hearts.

280 mbryos, and associate these differences with ICM/TE differences.

281 Canadian cities, scattered site housing with ICM services compared with usual access to existing hous

282 ntly and similarly improved in patients with ICM and NICM.

283 ntation therapeutic options in patients with ICM and NICM.

284 eriod of 41.4 +/- 29.0 months, patients with ICM had better survival when receiving CRT with a defibr

285 Mean total low voltage area in patients with ICM was 101 +/- 55 cm(2) and 56 +/- 33 cm(2), endocardia

286 Patients with ICM who received MSCs via transendocardial stem cell inj

287 ndocardial pacing varies among patients with ICM, and individual tailoring may improve CRT efficacy i

288 coronary BMC administration in patients with ICM, suggesting that the beneficial effects of BMC appli

289 urthermore, when compared with patients with ICM, the presence of T cells and macrophages was signifi

290 In this early-stage study of patients with ICM, transendocardial injection of allogeneic and autolo

291 questions in the management of patients with ICM.

292 ced myocyte size compared with patients with ICM.

293 to impaired cell retention in patients with ICM.

294 ht assist in the management of patients with ICM.

295 tracoronary BMC application in patients with ICM.

296 6 months, we found that 5% of subjects with ICM and 21% of subjects with NICM achieved left ventricu

297 udden cardiac death in 8.0% among those with ICM but in only 0.4% of those with DCM.

298 ar signal quantification and, for those with ICM, peri-infarct signal quantification.

299 ibrillator therapy, as opposed to those with ICM.

300 to the receptor(s) responding to FGF4 within ICM cells, we combined single-cell-resolution quantitati