ライフサイエンスコーパス: ICSI

1 ICSI offers no advantage over IVF in terms of clinical o

2 ICSI was performed in a programmed in vitro fertilizatio

3 r ICSI (total 435 treatment cycles: IVF 224; ICSI 211).

4 Analysis of pregnancies resulting from 987 ICSI cycles; pregnancy outcome data were obtained from t

5 thout male factor infertility (n = 317,996), ICSI use was associated with lower rates of implantation

6 difference between children conceived after ICSI and their naturally conceived peers in terms of phy

7 olled trial comparing clinical outcome after ICSI or traditional IVF in couples with non-male-factor

8 Reports of higher fertilisation rates after ICSI suggest that this technique may be better than the

9 patients fresh tissue provided sperm for an ICSI cycle.

10 productive outcomes for conventional IVF and ICSI cycles during 2008-2012, stratified by the presence

11 ive cohort study using data on fresh IVF and ICSI cycles reported to the US National Assisted Reprodu

12 surgical harvesting of testicular sperm and ICSI.

13 ded, treatment with microdissection TESE and ICSI are effective treatment options for many azoospermi

14 development, the removal of acrosomes before ICSI is recommended for animals with large sperm acrosom

15 m acrosomes, the removal of acrosomes before ICSI is theoretically preferable.

16 spermatozoa were freed from acrosomes before ICSI, regardless of the number of spermatozoa injected.

17 emembranated individually immediately before ICSI by using lysolecithin, a hydrolysis product of memb

18 studied 208 singleton children conceived by ICSI and a control group of 221 normally conceived singl

19 though the production of normal offspring by ICSI has been successful in mice and humans, it has been

20 s not a prerequisite to produce offspring by ICSI, but it resulted in earlier onset of oocyte activat

21 genital malformations following treatment by ICSI were within the range observed with standard in vit

22 the 578 neonates resulting from treatment by ICSI, 15 (2.6%) presented with congenital abnormalities

23 ions in mice produced by natural conception, ICSI and somatic cell nuclear transfer.

24 Among those cycles, ICSI use was associated with a lower multiple birth rate

25 portantly, some patients who repeatedly fail ICSI also fail to induce egg activation and are, therefo

26 ctable in sperm from patients who had failed ICSI.

27 at sperm from patients who repeatedly failed ICSI were unable to induce [Ca(2+)](i) oscillations in m

28 0.8 per 100,000 person-years); and following ICSI using ejaculated sperm and fresh embryos (RR, 1.47

29 creased risks of autistic disorder following ICSI using surgically extracted sperm and fresh embryos

30 son-years); for mental retardation following ICSI using surgically extracted sperm and fresh embryos

31 For ICSI, whether sperm were ejaculated or surgically extrac

32 spermatogenesis who might be candidates for ICSI with sperm obtained directly from the testis.

33 hypothesis, we uncoupled superovulation from ICSI by subjecting female mice to gonadotropin stimulati

34 ency of epimutations in somatic tissues from ICSI-derived mice.

35 (ICSI and cap), the control algorithm guided ICSI to quickly achieve and maintain the target temperat

36 Trends in ICSI use during 1996-2012 with respect to male factor in

37 ; for those without male factor infertility, ICSI use increased from 15.4% (4197/27,191) to 66.9% (42

38 Among cycles with male factor infertility, ICSI use increased from 76.3% (10,876/14,259) to 93.3% (

39 Intracarotid cold saline infusion (ICSI) is potentially much faster than whole-body cooling

40 atios with intracytoplasmic sperm injection (ICSI) (139 defects, 9.9%) were 1.77 (95% CI, 1.47 to 2.1

41 Using intracytoplasmic sperm injection (ICSI) and standard in vitro fertilization (IVF), we foun

42 nceived by intracytoplasmic sperm injection (ICSI) and who developed Angelman syndrome.

43 isation by intracytoplasmic sperm injection (ICSI) are at increased risk of neurodevelopmental delay.

44 outcome of intracytoplasmic sperm injection (ICSI) as a readout, we found that sperm with altered miR

45 to whether intracytoplasmic sperm injection (ICSI) for male infertility was used and whether embryos

46 Intracytoplasmic sperm injection (ICSI) has been used in combination with testicular sperm

47 Intracytoplasmic sperm injection (ICSI) is a more invasive option than conventional in-vit

48 Intracytoplasmic sperm injection (ICSI) is a technique that in vitro fertilization clinics

49 Intracytoplasmic sperm injection (ICSI) is increasingly used in patients without severe ma

50 n 5 min of intracytoplasmic sperm injection (ICSI) or somatic cell nuclear transfer (SCNT), and compl

51 nerated by intracytoplasmic sperm injection (ICSI) revealed that macroH2A is associated exclusively w

52 Intracytoplasmic sperm injection (ICSI) was initially developed as part of in vitro fertil

53 the use of intracytoplasmic sperm injection (ICSI), a type of ART.

54 rated that intracytoplasmic sperm injection (ICSI), a type of assisted reproductive technology (ART),

55 (IVF) with intracytoplasmic sperm injection (ICSI), can be used as an adjunctive measure to allow for

56 Intracytoplasmic sperm injection (ICSI), however, can enable men to achieve fatherhood, an

57 ination of intracytoplasmic sperm injection (ICSI), in vitro fertilization (IVF), sperm removal, rein

58 ved during intracytoplasmic sperm injection (ICSI).

59 n (IVF) or intracytoplasmic sperm injection (ICSI).

60 (TESE) and intracytoplasmic sperm injection (ICSI).

61 duction of intracytoplasmic sperm injection (ICSI).

62 ess called intracytoplasmic sperm injection (ICSI).

63 ng WT sperm-derived total or small RNAs into ICSI embryos.

64 Compared with conventional IVF, ICSI use was not associated with improved postfertilizat

65 cific instances in which sperm retrieval/IVF/ICSI may be a more appropriate treatment modality as ART

66 nted H19 gene in spermatogonia from juvenile ICSI-derived male mice.

67 The combination model had lower ICSI flow rates than the ICSI model resulting in a 55% r

68 In the ICSI and the combination models (ICSI and cap), the control algorithm guided ICSI to quic

69 One drawback of ICSI is hemodilution and volume loading.

70 of acrosomes may increase the efficiency of ICSI in these animals.

71 Furthermore, when pregnancy outcome of ICSI vs IVF was analyzed in terms of semen origin, no di

72 The ratio of ICSI procedures to diagnoses of male-factor infertility

73 ith insurance coverage had a higher ratio of ICSI use to diagnoses of male-factor infertility than di

74 , uncertain efficacy, and potential risks of ICSI, its use has been extended to include some patients

75 The percentage of IVF cycles with the use of ICSI also increased dramatically (from 11.0% to 57.5%),

76 , to determine temporal trends in the use of ICSI and IVF in the United States, and we examined diffe

77 s, and we examined differences in the use of ICSI between states with and those without mandated insu

78 d each year, suggesting an increasing use of ICSI for conditions other than male-factor infertility.

79 F services is associated with greater use of ICSI for infertility that is not attributed to male-fact

80 Since 1995, the use of ICSI in the United States has increased dramatically, wh

81 1999 to 2004, there was an increasing use of ICSI relative to the percentage of patients with male-fa

82 store-operated Ca(2+) entry had no effect on ICSI-induced egg activation, so Ca(2+) influx through al

83 ion of a single spermatozoon into an oocyte (ICSI) can produce apparently normal offspring.

84 our UK centres were randomly assigned IVF or ICSI (total 435 treatment cycles: IVF 224; ICSI 211).

85 their chance of fathering children by IVF or ICSI reduced by nearly two-thirds.

86 ith reduced incidence of pregnancy by IVF or ICSI, identifying SPTRX3 as a candidate biomarker reflec

87 as 44.3%, with a resultant delivery rate per ICSI cycle of 38.7% (n=382).

88 n 15-60 min after entry, and by 120 min post-ICSI or IVF, sperm were unable to induce oscillations.

89 ts support the current practice of reserving ICSI only for severe male-factor problems.

90 rgical reconstruction versus sperm retrieval/ICSI/IVF are neither randomized nor homogenous.

91 Among fresh IVF cycles in the United States, ICSI use increased from 36.4% in 1996 to 76.2% in 2012,

92 intracytoplasmic sperm injection technique (ICSI) from severely damaged spermatozoa that are no long

93 ies of postchemotherapy microdissection TESE-ICSI to date.

94 We discuss the possibility that ICSI may interfere with the establishment of the materna

95 A follow-up rate of 90% for the ICSI group was achieved at a mean age of 17 months.

96 We examined germ cells from the ICSI mice that exhibited epimutations in their somatic c

97 In the ICSI and the combination models (ICSI and cap), the cont

98 rate was higher in the IVF group than in the ICSI group (95/318 [30%] vs 72/325 [22%]; relative risk

99 Moreover, in the combination model, the ICSI flow rate decreased to zero after 4h, and hypotherm

100 Epimutations were detected in most of the ICSI-derived mice, but not in somatic cells of their off

101 ion model had lower ICSI flow rates than the ICSI model resulting in a 55% reduction of infusion volu

102 and higher hematocrit values compared to the ICSI model.

103 d Ca(2+) transient, whereas BAPTA/AM-treated ICSI or fertilized eggs cultured in Ca(2+)-free medium r

104 from 1996 through 2012, 908,767 (65.1%) used ICSI and 499,135 (35.8%) reported male factor infertilit

105 rain temperature control was developed where ICSI flow rate was varied based on the rate of temperatu

106 rate (per injected oocyte) was achieved with ICSI allowing a 50% clinical pregnancy rate with a live

107 The risk of birth defects associated with ICSI remained increased after multivariate adjustment, a

108 y significant, but the risks associated with ICSI using frozen embryos were significant for mental re

109 e risks of autistic disorder associated with ICSI using surgically extracted sperm were not statistic

110 ooling caps could enhance brain cooling with ICSI and minimize hemodilution and volume loading.

111 For specific procedures, IVF with ICSI for paternal infertility was associated with a smal

112 r absence of sperm, fertilization rates with ICSI, and final outcomes of pregnancy were recorded.

113 was significantly shorter with IVF than with ICSI (22.9 [SD 12.1] vs 74.0 [38.1] min; 95% CI for diff

114 ievable testis sperm, which may be used with ICSI to have healthy offspring.

115 IVF procedures used in Sweden vs IVF without ICSI with fresh embryo transfer, the most common treatme

116 Compared with IVF without ICSI with fresh embryo transfer, there were statisticall

117 mental retardation compared with IVF without ICSI.