ライフサイエンスコーパス: IHC

1 IHC analysis from Finasteride treated patients showed PC

2 IHC analysis of estrogen receptor, progesterone receptor

3 IHC and western blotting revealed reduction in epidermal

4 IHC confirmed increased cytokeratin 14 expression in fem

5 IHC expression of PD-L1 correlated strongly with PD-L1 (

6 IHC for MED15 was performed on 324 tissue samples, and T

7 IHC results were correlated with primary clinical and hi

8 IHC showed seemingly pronounced hyperexpression in subje

9 IHC study of human AD/stroke patients revealed co-locali

10 IHC subtyping was prognostic for IBR but was not predict

11 IHC was used to determine the presence of tumor infiltra

12 IHCs can generate CICR, but to date its physiological ro

13 IHCs lacking all three proteins showed excessive exocyto

14 related to cell death (assessed by caspase-3 IHC and cellular density) or tumor therapy response.

15 Distribution was 2.4% IHC 0, 7.9% IHC 1+, 84.8% IHC 2+, and 2.5% IHC 3+.

16 % IHC 0, 7.9% IHC 1+, 84.8% IHC 2+, and 2.5% IHC 3+.

17 tribution was 2.4% IHC 0, 7.9% IHC 1+, 84.8% IHC 2+, and 2.5% IHC 3+.

18 Distribution was 2.4% IHC 0, 7.9% IHC 1+, 84.8% IHC 2+, and 2.5% IHC 3+.

19 tion is warranted for patients with abnormal IHC test results, normal IHC test results with personal

20 ed in histologically negative LNs by AE1/AE3 IHC and carcinoembryonic antigen RT-PCR.

21 Among IHC 2+ patients, HER2 FISH positivity was 11.8% (FDA), 9

22 Through an IHC analysis of 248 human breast specimens, we found tha

23 aracterized by immunohistochemical analysis (IHC) for succinate dehydrogenase (SDH) subunit B, sequen

24 s confirmed by immunohistochemical analysis (IHC).

25 in expression (immunohistochemical analysis [IHC]), and gene amplification (fluorescent in situ hybri

26 irmed by BN-PAGE analysis of CI assembly and IHC using an alternative, commercially-available CI (NDU

27 blic databases of human breast carcinoma and IHC analysis of mice xenograft tumors demonstrated that

28 The use of histopathology, culture, and IHC plus PCR from full thickness skin biopsy can lead to

29 Pretreatment clinical, histologic, and IHC parameters did not differ significantly in the two t

30 plasm, as found by in situ hybridization and IHC, confirmed the virus specific induction of the HMGB1

31 DESI-MS imaging and IHC experiments confirmed that the spatial distribution

32 Combined MSI, methylation, and IHC analysis may prove useful in Lynch screening in EC.

33 to be highly correlative between RT-QuIC and IHC analysis.

34 tion, region of interest transformation, and IHC slide analysis.

35 w PrP(CWD) burdens, including those that are IHC-negative.

36 els normally coassemble with alpha2delta2 at IHC presynapses.

37 ge complement of synaptic Ca(2+) channels at IHC AZs and are required for normal hearing.

38 yelinated synaptic terminal segments beneath IHCs in the organ of Corti.

39 old effect: It abbreviated signaling between IHC and the auditory nerve and also balanced differences

40 eceptor potentials." Ribbon synapses between IHCs and auditory nerve neurons are responsible for conv

41 breast carcinoma tissue were tested by both IHC and ISH using standardized local methods.

42 By IHC, 76 specimens in the training cohort (54%) had high

43 biopsy specimens were analyzed for COX-2 by IHC.

44 ns of primary breast cancer were analyzed by IHC and ISH; HER2 and chromosome 17 centromere (CEP17) c

45 LNs from 298 patients were analyzed by IHC; 41 (14%) were IHC-positive (42% in N1 position, 58%

46 HLA class I expression in islets assessed by IHC was observed compared with that using quantitative t

47 evaluated for expression of MYC and BCL2 by IHC.

48 Results were confirmed by IHC and semiquantitative evaluation of T-cell infiltrati

49 Gene expression was confirmed by IHC for GAGE, SOX9, AMH, CYP17A1, LIN28, WNT2B, ETV5 and

50 Fibrosis was detected by IHC, hydroxyproline content, and by qPCR for fibrotic ma

51 for PD-L1 protein expression as detected by IHC.

52 n addition, cell of origin was determined by IHC and the Lymph2Cx gene expression assay in a subset o

53 with unresolved HER2 statuses (equivocal by IHC and in situ hybridization) was significantly higher

54 Conclusion COX-2 expression by IHC failed to select patients who could benefit from sel

55 In addition to ALK fusions identified by IHC/FISH in four cases, two previously known fusions inv

56 and signaling pathways were investigated by IHC analysis and immunofluorescence.

57 and tissues were stained for CD31 and KDR by IHC.

58 phatase and tensin homologue (PTEN) loss (by IHC) (30% of all patients), followed by mutations in PIK

59 i-institutional trial, the presence of OM by IHC staining in N2 LNs of patients with NSCLC correlated

60 strongly linked to protein overexpression by IHC in a spot-by-spot analysis (p < 0.0001).

61 issue samples that were negative for PCV2 by IHC analysis identified 45 of 48 that were PCV3 positive

62 that previously tested negative for PCV2 by IHC analysis.

63 f a subset also testing positive for PCV3 by IHC analysis.

64 itive breast cancers that are ER-positive by IHC analyses with low FISH ratio (>/=2 to <5), or with h

65 nt (n = 11), defined by detection of SDHB by IHC; and 2 types of SDH-deficient GIST (n = 84).

66 and diffuse nuclear positivity for STAT6 by IHC.

67 with these molecular findings, beta-catenin IHC showed consistent diffuse and strong nuclear stainin

68 ve to excitatory input from inner hair cell (IHC) ribbon synapses continued until approximately P30.

69 Yet inner hair cell (IHC) ribbons and auditory nerve responses showed signifi

70 lates fluid flow around the inner hair cell (IHC) stereocilia bundle.

71 The inner hair cell (IHC)/auditory nerve fiber (ANF) synapse is the first syn

72 hich innervate exclusively inner hair cells (IHCs) [2-4].

73 eneity of synapses between inner hair cells (IHCs) and SGNs is an attractive candidate mechanism for

74 nt ribbon synapses between inner hair cells (IHCs) and spiral ganglion neurons (SGNs) that carry acou

75 The inner hair cells (IHCs) are the primary sensory receptors adapted for rapi

76 he mature auditory system, inner hair cells (IHCs) convert sound-induced vibrations into electrical s

77 Wrb-deficient mouse inner hair cells (IHCs) displayed normal numbers of afferent synapses, Ca(

78 alian cochlea, the sensory inner hair cells (IHCs) encode auditory information.

79 FICANCE STATEMENT Auditory inner hair cells (IHCs) encode sounds into nerve impulses through fast and

80 Inner hair cells (IHCs) in the cochlea are the mammalian phono-receptors,

81 e normal synaptogenesis in inner hair cells (IHCs) in the newly identified mouse mutant pitch.

82 neous activity of cochlear inner hair cells (IHCs) is initiated by the release of ATP from glia-like

83 nd then diverge to contact inner hair cells (IHCs) or outer hair cells (OHCs), respectively.

84 the onset of hearing, the inner hair cells (IHCs) receive inhibitory efferent input from cholinergic

85 ned exocytosis in auditory inner hair cells (IHCs) remain largely unknown.

86 eveloping auditory system, inner hair cells (IHCs) spontaneously fire Ca(2+) spikes, each of which is

87 Inner hair cells (IHCs) were not significantly affected throughout the ent

88 ) currents of mature du/du inner hair cells (IHCs) were reduced by 30-40%, respectively, and gating p

89 r cells, preferentially in inner hair cells (IHCs), and was lacking from the postsynaptic spiral gang

90 Significance statement: Inner hair cells (IHCs), the auditory sensory cells of the cochlea, releas

91 tivity in immature sensory inner hair cells (IHCs), which is crucial for the refinement of the develo

92 tivity in immature sensory inner hair cells (IHCs), which is crucial for the refinement of the develo

93 pses of sensory cells, the inner hair cells (IHCs).

94 e functional maturation of inner hair cells (IHCs).

95 ncoding at the synapses of inner hair cells (IHCs).

96 nels at the AZs of sensory inner hair cells (IHCs).

97 0.124-0.340) using conventional chromogenic IHC and showed intra-assay heterogeneity (E1L3N coeffici

98 or and stroma was assessed using chromogenic IHC and the AQUA (Automated Quantitative Analysis) metho

99 Using chromogenic IHC, both antibodies showed fair to poor concordance.

100 al guar meal: raw churi (IRC), heated churi (IHC), final churi (IFC) and guar korma (IGK) were studie

101 d -negative cases that combines visual CLIP2 IHC scoring and CLIP2 genomic copy number status.

102 lying microarray technologies for conducting IHC on intact tissue slices and has great potential to b

103 similar to the one obtained by conventional IHC.

104 ased computational method on pan-cytokeratin IHC stainings to quantify tumor fragmentation (TF), a me

105 in and lymph nodes, 96% in asymptomatic deer IHC-positive in brain and lymph nodes and 53% in animals

106 demonstrate that AZs of RIM2alpha-deficient IHCs cluster fewer synaptic CaV1.3 Ca(2+) channels, resu

107 was predicted from pathology record-derived IHC markers by a classifier trained on PAM50 subtyping.

108 n respond to normal sound levels, developing IHCs fire calcium-based action potentials that disappear

109 Whereas the normal-developing IHCs display ribbon size gradients before hearing onset,

110 of depolarization-evoked exocytosis in du/du IHCs reflected their reduced Ca(2+) currents.

111 a2 protein expression was unchanged in du/du IHCs, forming clusters at presynaptic ribbons.

112 Remarkably, each IHC is the sole partner of 10-30 ANFs with a range of sp

113 ly inoculated aged pig were positive by EIA, IHC, and/or WB.

114 and group I-specific mGluR agonists enhances IHC efferent inhibition.

115 utamate released from the IHCs also enhances IHC efferent inhibition via the activation of group I mG

116 icant treatment effect was found for all ER, IHC, and FISH levels, except for the ER-positive/HER2 lo

117 Existing IHC methods use antibodies tagged with fluorophores or e

118 Finally, IHC analysis of CHK2 in prostate cancer patient samples

119 Finally, IHC and immunofluorescence analyses in TNBC specimens in

120 boratory cohort that was highly enriched for IHC 2+ patient samples, AC2013 guidelines led to a large

121 The faster kinetics of low-frequency IHCs allow them to follow the phasic component of sound

122 al role during transmission of activity from IHCs to SGNs before hearing onset.

123 and does not require glutamate release from IHCs.

124 Low-frequency gerbil IHCs (~0.3 kHz) have significantly more depolarized rest

125 th IHC positivity; however, patients who had IHC-positive N2 LNs had statistically significantly wors

126 SGNs must precisely connect with inner HCs (IHCs) while avoiding connections with nearby outer HCs (

127 iggers transmitter release from the immature IHC that in turn generates experience-independent firing

128 Immunohistochemical (IHC) results showed significantly reduced expression of

129 Structural and immunohistochemical (IHC) analyses showed preferential damage of photorecepto

130 Local ER immunohistochemical (IHC) analyses, HER2 fluorescence in situ hybridization (

131 th HPV serology and p16 immunohistochemical (IHC) measures available, both measures were similarly as

132 ults According to their immunohistochemical (IHC) profile, tumors were classified as human epidermal

133 Immunohistochemistry (IHC) analysis of sow tissue samples identified PCV3 anti

134 Immunohistochemistry (IHC) is currently considered the gold standard for diagn

135 Immunohistochemistry (IHC) on tissue sections is widely used for quantifying t

136 Immunohistochemistry (IHC) staining for tumor necrosis factor-alpha (TNF-alpha

137 Immunohistochemistry (IHC) use was mandatory, and SN metastases of any size, i

138 Immunohistochemistry (IHC) was performed on both pre- and posttreatment liver

139 proliferation by Ki-67 immunohistochemistry (IHC).

140 parative histology and immunohistochemistry (IHC) analyses further verified the effects of CypA defic

141 ybridization (ISH) and immunohistochemistry (IHC) combined with light (LM) and electron microscopy (E

142 onfocal microscopy and immunohistochemistry (IHC) to look for new cells in the motor cortex of adult

143 n of chromosome 9, and immunohistochemistry (IHC) using an antibody recognizing PD-L1 on formalin-fix

144 ase chain reaction and immunohistochemistry (IHC), in cellulo by TOP-Flash assay.

145 confirmed by qPCR and immunohistochemistry (IHC).

146 cal of PDNS in sows by immunohistochemistry (IHC) analysis.

147 YSLTR2 was analyzed by immunohistochemistry (IHC) and quantitative reverse transcription-polymerase c

148 ling were evaluated by immunohistochemistry (IHC) and Western blot (WB) analysis in brain samples fro

149 t the protein level by immunohistochemistry (IHC) followed by relative quantification using digital i

150 protein expression by immunohistochemistry (IHC) in 763 tissue biopsies.

151 ion of MYC and BCL2 by immunohistochemistry (IHC) is associated with poor outcome in diffuse large B-

152 fection post-mortem by immunohistochemistry (IHC).

153 gh COX-2 expression by immunohistochemistry (IHC).

154 advance over classical immunohistochemistry (IHC) in that it is rapid (4-8 h) and inexpensive, and it

155 yme immunoassay (EIA), immunohistochemistry (IHC), and in vitro real-time quaking-induced conversion

156 Her2 immunohistochemistry (IHC) was performed in addition.

157 studied by histology, immunohistochemistry (IHC), electron microscopy and neurosphere assay the morp

158 ted by histopathology, immunohistochemistry (IHC) staining for acid-fast bacilli (AFB), and mycobacte

159 protein expression in immunohistochemistry (IHC) images provides important diagnostic, prognostic an

160 and the proportion of immunohistochemistry (IHC) 2+ tumors was significantly lower in 2014 than in 2

161 compared to results of immunohistochemistry (IHC) analysis of ante- and postmortem samples.

162 Further experiments of immunohistochemistry (IHC) showed increased expression of cytoplasmic HMGB1 in

163 rn blotting, ELISA, or immunohistochemistry (IHC).

164 Pathologists published immunohistochemistry (IHC) and fluorescent in situ hybridization (FISH) HER2 t

165 y PET/CT and standard, immunohistochemistry (IHC)-based, histopathologic classification of human epid

166 patient cohorts using immunohistochemistry (IHC) (n = 48, n = 59) and expression was validated using

167 f KDR expression using immunohistochemistry (IHC) as the gold standard.

168 e assayed for OM using immunohistochemistry (IHC) for cytokeratin (AE1/AE3) and real-time reverse tra

169 Herein, we utilized immunohistochemistry (IHC) staining and public microarray data analysis showin

170 standardin vitroassay, immunohistochemistry (IHC) analysis.

171 Whereas immunohistochemistry (IHC) and immunoassays are routinely used for clinical an

172 MSI) typing along with immunohistochemistry (IHC) and MLH1 methylation analysis can help identify wom

173 piking, corroborating the notion of impaired IHC vesicle replenishment.

174 ourcing the scoring of protein expression in IHC images is a promising new approach for large scale c

175 and interpretation of protein expression in IHC images.

176 VHC-I had fewer synaptic ribbons (7 vs 17 in IHCs) to which Cav1.3 channels are more tightly organize

177 ximately 25%) of the total Ca(2+) current in IHCs displaying fast inactivation and resistance to 20 m

178 filament disruption increases exocytosis in IHCs and that actin filaments most likely position a fra

179 ion enhanced Ca(2+) influx and exocytosis in IHCs, reversed the spatial gradient of maximal Ca(2+) in

180 Consistent with a selective role of NO-GC in IHCs, NO-GC beta1 mRNA was found in isolated IHCs but no

181 spatial gradient of maximal Ca(2+) influx in IHCs, and increased the maximal firing rate of SGNs at s

182 prevents normal neurotransmitter release in IHCs and colocalization of presynaptic ribbons with post

183 channels are more tightly organized than in IHCs.

184 evation of cGMP was detected in real-time in IHCs but not in OHCs.

185 Within individual IHCs, presynaptic ribbons show a size gradient with larg

186 ory cells was able to increase the intrinsic IHC firing frequency.

187 ory cells was able to increase the intrinsic IHC firing frequency.

188 Here, we introduce IHC microarrays (IHCmuA) for multiplexed staining of int

189 IHCs, NO-GC beta1 mRNA was found in isolated IHCs but not in OHCs.

190 In connexin knockouts, IHCs remained stuck at a pre-hearing stage of developmen

191 mor-infiltrating lymphocytes (TIL) and PD-L1 IHC expression.

192 Patch-clamp recordings from Cabp2(LacZ/LacZ) IHCs revealed enhanced Ca(2+)-channel inactivation.

193 These data suggest that RT-QuIC, like IHC analysis, is a relatively sensitive assay for detect

194 These data suggest that RT-QuIC, like IHC analysis, is an effective assay for detection of PrP

195 onditions mimicking those in vivo, mammalian IHCs are intrinsically specialized.

196 patterns as per the tissue types in matched IHC images.

197 be required for hearing in young adult mice, IHCs from Cx30 knock-out mice exhibited a comprehensive

198 be required for hearing in young adult mice, IHCs from Cx30 knockout mice exhibited a comprehensive b

199 Moreover, IHC exocytosis is also reduced with mutant mice showing

200 rane capacitance during development of mouse IHCs.

201 es as a function of AZ position within mouse IHCs by combining patch clamp and imaging of presynaptic

202 ne carrier had an MSI-positive tumor with no IHC defect.

203 ients with abnormal IHC test results, normal IHC test results with personal or family history of othe

204 in efferent olivocochlear (OC) neurons, not IHCs or SGNs.

205 Since the amplitude of IHC receptor potentials is invariant during this period,

206 eplaced manual scoring for the assessment of IHC in the majority of diagnostic laboratories and in ma

207 c antagonist, indicating that enhancement of IHC efferent inhibition is mediated by group I mGluRs an

208 s captured well by our mathematical model of IHC electrical activity.

209 disadvantages, namely, the nonspecificity of IHC and immunoassays, and potentially long analysis time

210 roach is crowdsourcing the quantification of IHC images to an undefined crowd.

211 Manual scoring of IHC images represents a logistical challenge, as the pro

212 estimate the specificity and sensitivity of IHC and sPMCA conditional on simultaneously estimated di

213 is of RAMALT and would correspond to that of IHC analysis of postmortem tissues.

214 ty of RT-QuIC would be comparable to that of IHC analysis of RAMALT and would correspond to that of I

215 (8.4%) can be achieved with mandatory use of IHC.

216 markedly reduces the spontaneous activity of IHCs and spiral ganglion neurons in the developing cochl

217 Patch-clamp of IHCs revealed impaired synaptic vesicle replenishment.

218 of the model that predicts the dependence of IHCs firing patterns on the level of activation of two p

219 efflux, causing transient depolarization of IHCs near ATP release sites.

220 The intrinsic membrane filtering of IHCs ensures accurate encoding of the phasic or sustaine

221 ut mice (Cx26(Sox10-Cre)), the maturation of IHCs, which normally occurs at approximately postnatal d

222 out mice (Cx26(Sox10-Cre)) the maturation of IHCs, which normally occurs at around postnatal day 12,

223 cally localized at the presynaptic region of IHCs.

224 included in the analysis, KDR expression on IHC matched well with imaging signal on USMI in 93% of b

225 I signal matches well with KDR expression on IHC.

226 -type IHCs but poorly expressed in Otof(-/-) IHCs, the latter having Ca(2+) currents with considerabl

227 alidated quadruple immunofluorescent OXPHOS (IHC) assay to detect CI deficiency in the diagnostic set

228 We performed p15 and p16 IHC analyses on a random series of nevi and melanomas.

229 Photopic ERG, visual evoked potentials, IHC and cell counting indicated relatively long survivin

230 te mutants should be identified with precise IHC criteria or mutation screening.

231 ssipation in the STS because of the presence IHC stereocilia increased as the stimulating frequency d

232 found that the colocalization of presynaptic IHC ribbons and postsynaptic afferent terminals is great

233 EF-hand Ca(2+) buffers regulate presynaptic IHC function for metabolically efficient sound coding.

234 The aim of this study is to quantify IHC images for labeling of ER status with two different

235 n from the nucleus to the cytoplasm in rats (IHC score = 0; 10 mg/kg po, 6 h) and blood glucose reduc

236 egative feedback loop positioned to regulate IHC activity and maturation of the ascending auditory sy

237 We propose that Np65, by regulating IHC synaptogenesis, is critical for auditory function in

238 Results IHC results were available for 1,922 patient samples (67

239 t fibers with different SRs contact the same IHCs and do not show correlated spike timing at rest.

240 proliferation (BrdUrd flow cytometry, spleen IHC; 6 hours/day 1); and (iii) reduced leukocytes in per

241 spectively, when compared with gold-standard IHC.

242 Upon sound stimulation, IHCs release glutamate to activate AMPA-type receptors o

243 However, surviving IHCs lost synaptic connectivity to remaining SGNs in all

244 51%, credible interval (CI) 97.15-100%) than IHC of obex (brain stem, 76.56%, CI 57.00-91.46%) or ret

245 -QuIC has greater detection sensitivity than IHC in tissues with low PrP(CWD) burdens, including thos

246 We propose that IHC functional differentiation into mature sensory recep

247 We propose that IHC functional differentiation into mature sensory recep

248 We propose that IHCs diversify Ca(2+) channel properties among AZs and t

249 We propose that IHCs use dynamin-dependent endocytosis via CME to suppor

250 Using connexin knock-out mice, we show that IHCs fire spontaneous action potentials even in the abse

251 Using connexin knockout mice, we show that IHCs fire spontaneous APs even in the absence of ATP-dep

252 We show that IHCs of hearing mice express mainly RIM2alpha, but also

253 The IHC assay has clear diagnostic potential to identify pat

254 The IHC examination of human CCA specimen for VDR revealed t

255 The IHC ribbon size gradient is also perturbed.

256 The IHC ribbon synapse structure, synaptic Ca(2+) currents,

257 The IHC signal distribution was consistent with ISH results,

258 The IHC stereocilia stiffness and the gap size between the I

259 dominated by the viscous friction around the IHC stereocilia bundle--the IHC stereocilia increased th

260 pothesis pointed to vesicle depletion at the IHC as responsible for auditory adaptation.

261 y the Neuroplastin gene, is localized at the IHC presynaptic region.

262 pse contribute to synaptic depression at the IHC ribbon synapse and spike rate adaptation in the audi

263 both pre- and postsynaptic mechanisms at the IHC ribbon synapse contribute to synaptic depression at

264 cilia stiffness and the gap size between the IHC stereocilia and the tectorial membrane determine the

265 impedes processes from extending beyond the IHC region.

266 ction around the IHC stereocilia bundle--the IHC stereocilia increased the STS power dissipation by 5

267 The model combining the IHC subtype, ADC ratio, and late enhancement had the hig

268 d synaptic vesicle pool replenishment in the IHC active zone.

269 rating frequency, the active motility of the IHC stereocilia bundle reduced the power dissipation in

270 When the mechano-transduction of the IHC was tuned near the vibrating frequency, the active m

271 To achieve this task, the IHC relies on the recruitment of glutamate-filled vesicl

272 he heminode, which is tightly coupled to the IHC ribbon synapse approximately 20-40 mum away.

273 lts suggest that glutamate released from the IHCs activates group I mGluRs (mGluR1s), probably presen

274 over, endogenous glutamate released from the IHCs also enhances IHC efferent inhibition via the activ

275 fibres with patch clamp recordings from the IHCs to measure efferent synaptic strength.

276 mation to the ascending auditory nuclei, the IHCs firing pattern controlled by the alpha9alpha10 rece

277 lease of acetylcholine and inhibition of the IHCs.

278 em by inhibiting spontaneous activity of the IHCs.

279 te the molecular mechanisms regulating these IHC efferent synapses, we combined electrical stimulatio

280 efferent terminals are sufficiently close to IHC glutamate release sites to allow activation of mGluR

281 ensitivity of RT-QuIC would be comparable to IHC analysis in antemortem tissues and would correlate w

282 lso found that connexin expression is key to IHC functional maturation.

283 lso found that connexin expression is key to IHC functional maturation.

284 , which carry approximately 75% of the total IHC Ca(2+) current with slow inactivation and confer hig

285 The latter was accomplished by triple IHC for gli2+ (marker of Hh signaling), sox-9 (progenito

286 gnal amplification immunohistochemistry (TSA-IHC).

287 their mRNA is highly expressed in wild-type IHCs but poorly expressed in Otof(-/-) IHCs, the latter

288 udy, we evaluated specificity of RK-10 using IHC in over 200 patient tissues, including NSCLC and Hod

289 to the bone marrow, which we assessed using IHC analysis.

290 ons were analyzed for PD-L1 expression using IHC.

291 patients were analyzed by IHC; 41 (14%) were IHC-positive (42% in N1 position, 58% in N2 position).

292 ositive for M. marinum group species, 8 were IHC positive, and 3 were positive by AFB stains.

293 mals with very poor body condition that were IHC-positive in both brain and lymph nodes, 96% in asymp

294 imals at early stages of infection that were IHC-positive only in lymph nodes.

295 on protein (PrP(C) ) were also assessed with IHC and WB analysis.

296 or disease-free survival was associated with IHC positivity; however, patients who had IHC-positive N

297 Use of our in situ assay in conjunction with IHC or immunofluorescence uncovered a surprisingly mosai

298 We recommend that SN evaluation with IHC be further evaluated before being included in future

299 diagnosed at age < 60 years or to women with IHC defects could result in missing a substantial fracti

300 Ns contact OHCs before forming synapses with IHCs.