ライフサイエンスコーパス: IHNV

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1 VCV-G), elicited protective immunity against IHNV.

2 d at least two functions for M protein in an IHNV infection: down regulation of host transcription an

3 or by a hybrid protein composed of SHRV and IHNV sequences.

4 vaccines, each encoding the G gene of either IHNV (IHNV-G), snakehead rhabdovirus (SHRV) (SHRV-G), or

5 at superinfection restriction does occur for IHNV and that higher virulence did not correlate with a

6 these particles, the kidneys and livers from IHNV survivors were harvested and divided into samples f

7 Furthermore, IHNV infection was shown to produce DNA "laddering" in c

8 es, each encoding the G gene of either IHNV (IHNV-G), snakehead rhabdovirus (SHRV) (SHRV-G), or sprin

9 our data also suggest that LJ001-inactivated IHNV elicited an innate immune response in the rainbow t

10 cells with soluble recombinant FN2 increased IHNV infection, as measured by plaque assay.

11 immobilized on the culture surface inhibited IHNV infection.

12 tissue culture infective doses/ml for IPNV, IHNV, and VHSV, respectively.

13 esent on the cell surface is able to mediate IHNV attachment and cell entry.

14 70 days postvaccination with lethal doses of IHNV.

15 nfection cycle contributes to the fitness of IHNV genotypes that differ in virulence in rainbow trout

16 e, the more virulent of the two genotypes of IHNV we used had advantages in all of the traits quantif

17 Incubation of IHNV with soluble FN2 before addition to cells also incr

18 We demonstrated inhibition of IHNV by LJ001 both in cell culture as well as in live fi

19 wed that LJ001 inhibited the transmission of IHNV from infected fish to healthy fish, which lays the

20 While horizontal transmission of IHNV in a static cohabitation challenge model was reduce

21 ultures were infected with purified standard IHNV, the liver tissues from survivor fish produced up t

22 ections with lower virus-shedding rates than IHNV or where higher viral titers are required to initia

23 hich the NV gene of VHSV was replaced by the IHNV NV gene, which was capable of suppressing apoptosis

24 Sequences for the IHNV nucleoprotein and polymerase genes were detected in

25 ficant inhibition in the accumulation of the IHNV nucleoprotein was observed in cells expressing eith

26 at 70 days postvaccination, only 12% of the IHNV-G-vaccinated fish died compared to 68% for the SHRV

27 allenge, all of the fish vaccinated with the IHNV-G plasmid were negative for Mx, but the SHRV-G- and

28 ing recombinant FN2 were more susceptible to IHNV infection, with a greater percentage of cells exhib

29 These results suggest that the truncated IHNV particles observed in persistently infected fish ar

30 and infectious hematopoietic necrosis virus (IHNV) are members of the genus Novirhabdovirus within th

31 rus infectious hematopoietic necrosis virus (IHNV) as a model to study aquatic enveloped virus diseas

32 Infectious hematopoietic necrosis virus (IHNV) infection in tissue culture cells has previously b

33 Infectious hematopoietic necrosis virus (IHNV) is a rhabdovirus that produces an acute, lethal in

34 of infectious hematopoietic necrosis virus (IHNV) or by a hybrid protein composed of SHRV and IHNV s

35 V), infectious hematopoietic necrosis virus (IHNV), and viral hemorrhagic septicemia virus (VHSV).

36 us, infectious hematopoietic necrosis virus (IHNV), infectivity was significantly inhibited in vitro

37 rus Infectious hematopoietic necrosis virus (IHNV).

38 by infectious hematopoietic necrosis virus (IHNV).

39 ith infectious hematopoietic necrosis virus (IHNV).

40 rus infectious hematopoietic necrosis virus (IHNV).

41 en, infectious hematopoietic necrosis virus (IHNV).

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