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1 cytokine, IL-7, due to reduced expression of IL-7 receptor.
2 feration results from signals other than the IL-7 receptor.
3 found to have mutations in the gene for the IL-7 receptor.
4 al interleukin receptors, including IL-2 and IL-7 receptors.
5 y depends on signaling through both IL-2 and IL-7 receptors.
6 SCs express lowered levels of interleukin-7 (IL-7) receptor.
7 ated CD4(+) T cells expressed high levels of IL-7 receptor a chain but very low levels of TSLP recept
8 nterleukin 2 (IL-2) receptor a-chain (CD25), IL-7 receptor a-chain (CD127) and the IL-33 receptor sub
11 s via a receptor comprising the interleukin (IL)-7 receptor alpha chain and a distinctive subunit, TS
14 cking IL-7 signaling with a mAb that targets IL-7 receptor alpha (IL-7Ralpha) alone or following T ce
18 for thymopoiesis in mice and humans because IL-7 receptor alpha (IL-7Ralpha) mutations result in a s
20 blastic leukemia cell line, using lentiviral IL-7 receptor alpha (IL-7Ralpha) to serve as a model sys
21 in T-cell development caused by mutations in IL-7 receptor alpha (IL7RA) and IL-2 receptor gamma (IL2
22 IL-7 led to transient down-regulation of the IL-7 receptor alpha chain (CD127) in both CD4(+) and CD8
25 e that IL-2 potently decreases expression of IL-7 receptor alpha chain (IL-7Ralpha) mRNA and protein.
26 etal liver but not adult bone marrow (BM) of IL-7 receptor alpha chain (IL-7Ralpha)-deficient mice ca
27 T cells with decreased expression of CD127 (IL-7 receptor alpha chain) and (b) nonalloreactive T cel
28 ow that pDCs expressed the TSLP receptor and IL-7 receptor alpha complexes upon activation and became
29 f the patient, and showed that patients with IL-7 receptor alpha, ADA, and CD3 chain gene mutations c
30 dexamethasone upregulated ILC2 expression of IL-7 receptor alpha, which augmented and sustained signa
33 he survival of naive and memory T cells, and IL-7 receptor alpha-chain (IL-7Ralpha) expression is dyn
34 g many acute viral and bacterial infections, IL-7 receptor alpha-chain (IL-7Ralpha) is expressed on a
35 in the expression of the transcript for the IL-7 receptor alpha-chain (IL-7Ralpha), and these result
38 ys an important role in the transcription of IL-7 receptor alpha-subunit (CD127), enabling responsive
44 ished use of IL-7 but that IL-7 signaling on IL-7 receptor-alpha-positive (IL-7Ralpha(+)) dendritic c
47 ptors - such as c-kit, flt3/flk2, CXCR4, the IL-7 receptor and the IL-15 receptor - are known to prom
48 etermine whether eosinophils have functional IL-7 receptors and to assess the potential contribution
51 eceptor signals, such as those transduced by IL-7 receptors, are required for differentiation of sign
53 like other T cells, require signals from the IL-7 receptor, but unlike other T cells, do not require
59 with the common gamma-chain (gammac) in the IL-7 receptor complex and the unique TSLP-R chain in the
61 SPGs on B-lineage precursors may function as IL-7 receptor components similar to HSPGs known to be im
67 etitively to RAG2(-/-) mice (with ILC2s) and IL-7 receptor-deficient mice (lack ILC2s), and total ILC
70 cells and by permanently upregulating their IL-7 receptor expression, enabling IL-7 to sustain them
71 not inhibit lymphopoiesis by down-regulating IL-7 receptor expression, since this cytokine did not re
74 le negative) thymocytes require interleukin (IL)-7 receptor (IL-7R) signals for survival and prolifer
75 ingly, gene disruption of either IL-7 or the IL-7 receptor (IL-7R) alpha subunit in mice leads to imm
81 active B cells, required the function of the IL-7 receptor (IL-7R), and contributed to maintenance of
82 8(+) T cells normally express high levels of IL-7 receptor (IL-7R, CD127), activated and memory allor
85 murine T-cell line, different regions of the IL-7 receptor initiate the signal transduction pathways
86 (+) subpopulations demonstrates that surface IL-7 receptor is expressed on most CD34(high)CD5(+)CD1a(
87 antiapoptotic function of the interleukin-7 (IL-7) receptor is related to regulation of three members
89 D4 effectors generated from wild-type versus IL-7 receptor-/- mice were transferred to adoptive hosts
90 aused a downregulation of the interleukin-7 (IL-7) receptor, needed for survival of conventional T ce
91 ogeneic bone marrow transplant studies using IL-7 receptor null (IL-7R alpha(-/-)) mice as recipients
94 ith heterodimeric cytokine receptors such as IL-7 receptor or IL-9 receptor, in which JAK1 is appende
95 rs contribute to a dysregulation of the IL-7/IL-7 receptor pathway in T1D and identify a novel hyperg
98 Previously it was known that the IL-2 and IL-7 receptors shared the common cytokine receptor gamma
104 velopmental downregulation of interleukin 7 (IL-7)-receptor signaling in small pre-B cells induced ex
105 ines whose receptors share components of the IL-7 receptor: thymic stromal lymphopoietin (TSLP) and I
106 ly, sIL7Ralpha competes with cell-associated IL-7 receptor to diminish excessive IL-7 consumption and
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