ライフサイエンスコーパス: IMP dehydrogenase

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1 ave been prepared as potential inhibitors of IMP dehydrogenase.

2 the most potent cofactor type inhibitors of IMP dehydrogenase.

3 nthosine 5'-monophosphate (XMP) catalyzed by IMP dehydrogenase.

4 d as inhibitors of the two isoforms of human IMP-dehydrogenase.

5 Inosine monophosphate (IMP) dehydrogenase 2 (IMPDH2) is a rate-limiting enzyme

6 l functions of the IMPDH homologs aside from IMP dehydrogenase activity.

7 MPA is an inhibitor of IMP dehydrogenase, an enzyme necessary for the de novo b

8 nery render yeast sensitive to inhibitors of IMP dehydrogenase and defective in inducing transcriptio

9 furin, or ribavirin, which are inhibitors of IMP dehydrogenase, as inducers.

10 tive in inducing transcription of one of the IMP dehydrogenase-encoding genes, IMD2.

11 The putative Candida IMP dehydrogenase gene (IMH3) encodes a protein of 521 a

12 An IMP dehydrogenase gene was isolated from Candida albican

13 osyltransferase (DRTase, encoded by bb0426), IMP dehydrogenase (GuaB) and GMP synthase (GuaA) catalys

14 o key enzymes in purine salvage pathways are IMP dehydrogenase (GuaB) and GMP synthase (GuaA), encode

15 ymes, adenylosuccinate synthetase (PurA) and IMP dehydrogenase (GuaB) in these strains.

16 n cells unable to convert IMP to XMP or AMP (IMP dehydrogenase, guaB; adenylosuccinate synthetase, pu

17 ve-site sequence of At IMPDH conforms to the IMP dehydrogenase/guanosine monophosphate reductase moti

18 e conformation of IMP bound to human type II IMP dehydrogenase has been determined by two-dimensional

19 of ribavirin, suggesting that inhibition of IMP dehydrogenase (IMPDH) and reduction of intracellular

20 IMP dehydrogenase (IMPDH) catalyzes the NAD-dependent sy

21 IMP dehydrogenase (IMPDH) catalyzes the oxidation of IMP

22 IMP dehydrogenase (IMPDH) catalyzes the oxidation of IMP

23 IMP dehydrogenase (IMPDH) catalyzes the oxidation of IMP

24 IMP dehydrogenase (IMPDH) catalyzes the oxidation of IMP

25 IMP dehydrogenase (IMPDH) catalyzes the oxidation of ino

26 IMP dehydrogenase (IMPDH) catalyzes the pivotal step in

27 IMP dehydrogenase (IMPDH) catalyzes the rate-limiting st

28 IMP dehydrogenase (IMPDH) catalyzes two very different c

29 IMP dehydrogenase (IMPDH) is an essential enzyme that ca

30 IMP dehydrogenase (IMPDH) is the rate-limiting enzyme fo

31 IMP dehydrogenase (IMPDH) is the rate-limiting enzyme in

32 Previously, we proposed that IMP dehydrogenase (IMPDH) was an essential factor for p5

33 The Bateman domain (CBS subdomain) of IMP dehydrogenase (IMPDH), a rate-limiting enzyme of the

34 e agent mizoribine and a potent inhibitor of IMP dehydrogenase (IMPDH).

35 Mycophenolic acid (MPA), an inhibitor of IMP-dehydrogenase (IMPDH), is used worldwide in transpla

36 ), which is a potent inhibitor of eukaryotic IMP dehydrogenases (IMPDHs).

37 stemin protein degradation in tumor cells by IMP dehydrogenase inhibition or by other small molecules

38 ld temperature, nutrient limitation, and the IMP dehydrogenase inhibitor mycophenolic acid (MPA).

39 tive secretory vacuoles, we hypothesize that IMP dehydrogenase inhibitors induce androgen-independent

40 IMP dehydrogenase is a rate-limiting enzyme involved in

41 itor of the de novo purine synthetic enzyme, IMP dehydrogenase, leads to the rapid disappearance of n

42 IMP dehydrogenase mRNAs are detected in both the yeast a

43 ds with extensive sequence similarity to the IMP dehydrogenases of Saccharomyces cerevisiae and vario

44 Inosine 5'-monophosphate dehydrogenase (IMP dehydrogenase or IMPDH) is a promising target for th

45 phenolic acid (MPA), a specific inhibitor of IMP dehydrogenases, per ml, whereas transformants hostin

46 ar motor switch protein and the guaB-encoded IMP dehydrogenase) were noninfectious, whereas four clon

47 bavirin (RBV) lies in its ability to inhibit IMP dehydrogenase, which lowers cellular GTP.

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